Longitudinal sex and stress hormone profiles among reproductive age and post-menopausal women after severe TBI: A case series analysis

Brain Injury ◽  
2016 ◽  
Vol 30 (4) ◽  
pp. 452-461 ◽  
Author(s):  
Prerna Ranganathan ◽  
Raj G. Kumar ◽  
Kendra Davis ◽  
Emily H. McCullough ◽  
Sarah L. Berga ◽  
...  
Keyword(s):  
Case Series ◽  
Reproductive Age ◽  
Stress Hormone ◽  
Series Analysis ◽  
Menopausal Women ◽  
Severe Tbi ◽  
Post Menopausal

scholarly journals STUDY OF SERUM LIPID PROFILE IN REPRODUCTIVE AND POST MENOPAUSAL WOMEN.

2019 ◽  
Vol 3 (9) ◽  
Author(s):  
Dr. Chanchal Shrivastav ◽  
Dr. Akshay Berad ◽  
Dr. Paras Arvindbhai Parekh
Keyword(s):  
Risk Factors ◽  
Cardiovascular Disease ◽  
Heart Disease ◽  
Cardiovascular Risk ◽  
Lipid Profile ◽  
Serum Lipid ◽  
Reproductive Age ◽  
Age Group ◽  
Menopausal Women ◽  
Post Menopausal

According to WHO estimates, 16.7 million people around the globe die of cardiovascular disease each year. Economic transition, urbanization, industrialization and globalization bring about life style changes that promote heart disease. High blood pressure, high cholesterol and obesity are likely to become more prevalent in developing countries. Increased energy intake and sedentary lifestyle are also responsible for heart disease. The presence of one or more cardiovascular risk factors like high levels of TC, LDL, TG, glucose, insulin, BMI and a decreased HDL have been found to increase the progression of prehypertension to hypertension. Prehypertension increases the risk of MI and CAD. The present study was   undertaken to know serum lipid profile changes in reproductive and postmenopausal women. Total 60 Subjects of age group 20-45years (reproductive), 46-60years (postmenopausal) female volunteered for our study. During the study period, BMI, Lipid profile, parameters were recorded in all the subjects. In BMI, TC, LDL, VLDL, TG, is gradually increased, HDL is gradually decreased from reproductive age women to post menopausal women. Dyslipidemia occurs due to multifactorial reasons like physical activity, life style, diet, smoking, alcohol consumption, ethnicity and genetic makeup. Post-menopausal women are at increased risk of developing cardiovascular disease due to change in the lipid pattern and loss of cardioprotective effect of estrogen. Predicting the factors affecting the lipid profile in post-menopausal women, adopting strategies to control these mechanisms by modifying the relative risk factors during menopausal transition may improve the cardiovascular risk profile in these women. Keyword:  Lipid profile, Menopause, Reproductive age group.

scholarly journals A rare case report of gestational trophoblastic disease in peri menopausal women

2020 ◽  
Vol 9 (11) ◽  
pp. 4716
Author(s):  
Nagashree U. ◽  
Wahida Suresh
Keyword(s):  
Early Recognition ◽  
Gestational Trophoblastic Disease ◽  
Reproductive Age ◽  
Trophoblastic Disease ◽  
Menopausal Women ◽  
Rare Case Report ◽  
Abnormal Bleeding ◽  
Post Menopausal ◽  
Reproductive Age Group

Benign gestational trophoblastic disease (GTD) generally occurs in reproductive age group women; but is extremely rare in peri and post-menopausal women. We report a case of molar pregnancy in a 48-year-old lady with complaints of bleeding per vaginum with severe pain abdomen. The intention was to highlight the need to include GTD as a possible cause of abnormal bleeding per vaginum in peri and post-menopausal women. So early diagnosis and management with proper follow up is possible. It stresses the need for early recognition to avoid high malignant sequelae.

scholarly journals ASYMPTOMATIC LABIAL FUSION DIAGNOSED DURING LABOUR -(A CASE REPORT)

2020 ◽  
pp. 35-36
Author(s):  
Anshu Baser ◽  
Bhoomika Jain ◽  
Sushil Kumar
Keyword(s):  
Reproductive Age ◽  
Age Group ◽  
Women Of Reproductive Age ◽  
Labia Minora ◽  
Labial Fusion ◽  
Menopausal Women ◽  
History Of ◽  
Post Menopausal ◽  
Prepubertal Age ◽  
Reproductive Age Group

Labial fusion is when the labia minora of the vulva fuse together. This most commonly occurs in prepubertal age group(0.6%-5%).(1) This condition rarely occurs in adults and even in adults it is seen in post menopausal women and may result in urinary incontinence.(2) It is extremely rare in women of reproductive age group and only a few cases have been reported so far.(3) We here report a case of a 25 year old female with asymptomatic labial fusion with no history of voiding difficulty, dyspareunia who presented to us at term in labour.

EVALUATION OF SERUM TSH IN PREMENOPAUSAL AND POST MENOPAUSAL WOMEN IN A TERTIARY CARE HOSPITAL

2021 ◽  
pp. 30-33
Author(s):  
Elvis Vishal Saurabh Saurabh Dadel ◽  
Tarique Aziz ◽  
Asha Premlata Omega Oraon
Keyword(s):  
Statistical Analysis ◽  
Postmenopausal Women ◽  
Tertiary Care ◽  
Premenopausal Women ◽  
Reproductive Age ◽  
P Value ◽  
Care Hospital ◽  
Menopausal Women ◽  
Post Menopausal ◽  
Serum Tsh

Objective- To evaluate and compare the level of TSH in premenopausal women (reproductive age group) and post-menopausal women. Material And Methods- The study was carried out on 100 premenopausal and 100 post-menopausal women attending Out Patient Departments at RIMS, Ranchi, during the period of January 2018- October 2019. Study Design: - Observational Study. Statistics- Statistical analysis was done using SPSS software. The data were represented by counts, percentage and mean ± standard deviation. Statistical analysis of TSH was done by t-test to compare these parameters in premenopausal and post-menopausal women. A p-value of <0.05 was considered statistically signicant. Result- In the present study, we found that the mean serum TSH level in postmenopausal women 2.72 (± 1.06) uIU/ml was comparatively higher than premenopausal women 2.29 (±1.12) uIU/ml and the difference between the two was statistically signicant (p<0.001). Conclusion- Thyroid hormones play an important role in maintaining normal reproductive behaviour by directly effecting on gonadal function and indirectly interacting with sex hormone binding protein. Alteration of thyroid hormone level leads to menstrual irregularities and infertility. The present study clearly demonstrated that there was signicant increase in TSH levels in post-menopausal women and was statistically signicant. Thus, it proved that postmenopausal women are more prone to subclinical hypothyroidism.

scholarly journals Borderline Papillary Serous Tumour of the Peritoneum

2018 ◽  
Vol 8 (2) ◽  
pp. 69-72 ◽  
Author(s):  
Md Mustafizur Rahman ◽  
Md Abul Kalam Azad ◽  
Nadim Ahmed ◽  
Nazmin Rahman ◽  
Muhammad Raquib Hussain
Keyword(s):  
Ovarian Tumour ◽  
Reproductive Age ◽  
Borderline Tumour ◽  
Medical College ◽  
Menopausal Women ◽  
Rare Lesion ◽  
Ovarian Pathology ◽  
Post Menopausal ◽  
Upper Abdomen ◽  
Reproductive Age Group

Primary borderline serous peritoneal tumour is a rare lesion found in the absence of ovarian pathology, in the presence of minimal ovarian involvement or in association with benign ovarian tumour. It is thought to arise from the mullerian system, which is embryologically derived from the coelomic and sub-coelomic mesenchyme, and therefore shares histologic similarities with ovarian serous tumours. Such tumours are mostly found in women of reproductive age group although cases have been reported for post-menopausal women. We report a case of a primary peritoneal borderline tumour diagnosed in a middle aged patient with lump and pain the upper abdomen in Shaheed Suhrawardy Medical College & Hospital.J Shaheed Suhrawardy Med Coll, December 2016, Vol.8(2); 69-72

scholarly journals Assessing the Concordance Between Urogenital and Vaginal Microbiota: Can Urine Specimens Be Used as a Proxy for Vaginal Samples?

2021 ◽  
Vol 11 ◽  
Author(s):  
Sarah E. Brown ◽  
Courtney K. Robinson ◽  
Michelle D. Shardell ◽  
Johanna B. Holm ◽  
Jacques Ravel ◽  
...  
Keyword(s):  
Vaginal Microbiota ◽  
Reproductive Age ◽  
Urine Samples ◽  
Kappa Statistics ◽  
Rrna Gene ◽  
State Type ◽  
Menopausal Women ◽  
Significant Difference ◽  
Post Menopausal ◽  
Tract Infections

BackgroundThe vaginal microbiota play a key role in defense against reproductive tract infections; however, many population-based women’s health studies do not collect vaginal samples. Molecular examinations of urine samples have revealed common vaginal bacteria. We sought to assess the extent that community state type assignments of archived random-catch and clean-catch urine samples agreed with the paired vaginal samples in both reproductive-age and peri/post-menopausal women.ResultsUsing archived samples, we evaluated the microbiota concordance among women in three studies: two with paired mid-vaginal/random-catch urine (N=91 reproductive-age participants and N=13 peri/post-menopausal participants), and one with paired mid-vaginal/clean-catch urine (N=99 reproductive-age participants). Microbiota composition was characterized by sequencing amplicons of the 16S rRNA gene V3-V4 regions and assigned to community state types. Similarity of paired samples was gauged using agreement of community state types and Yue-Clayton θ indices. Analysis of Composition of Microbiomes II indicated which taxa were differently relatively abundant in paired vaginal and urine samples. In reproductive-age women, random-catch and clean-catch urines were 89.0% and 86.9% concordant on five community state types with paired mid-vaginal swabs, and Kappa statistics indicated almost perfect agreement (κrandom-catch=.85, κclean-catch=.81, p&lt;0.0001). A small number of pairs of samples were discordant (23/190, 12%), and discordant pairs tended to be between samples classified to L. iners-dominated and/or low-Lactobacillus states. Concordance and agreement remained similar when dichotomizing the microbiota to Lactobacillus-dominated versus low-Lactobacillus microbiota, as well as when evaluating separately the three subtypes of the low-Lactobacillus community state type IV. Median similarity of paired urine/vaginal samples was high (θrandom-catch=.85, θclean-catch=.88), and a comparison of the random-catch and clean-catch similarity scores showed no significant difference (p=.80). Concordance and similarity were lower for peri/post-menopausal women, but agreement remained substantial (76.9% concordant, κrandom-catch= 0.64, θrandom-catch=.62). Taxonomic-level analysis confirmed these findings.ConclusionsRandom-catch and clean-catch urine samples showed substantial agreement on bacterial composition to paired mid-vaginal samples, indicating that the genitourinary microbiota may be a reliable proxy for assessing the overall composition of the vaginal microbiota via community state types. This data suggests that urine samples can, with proper interpretation, be utilized as a surrogate for developing preliminary data and hypothesis-generating studies.

scholarly journals Determining a threshold measurement of Endometrial Thickness for Asymptomatic Postmenopausal Women: A single-centre case series

2021 ◽  
Author(s):  
Amy Stewart ◽  
Gurjot Gill ◽  
Emma Readman ◽  
Sonia Grover ◽  
Samantha Mooney
Keyword(s):  
Postmenopausal Women ◽  
Endometrial Hyperplasia ◽  
Endometrial Thickness ◽  
Case Series ◽  
Retrospective Case ◽  
Endometrial Sampling ◽  
Pathology Classification ◽  
Menopausal Women ◽  
The Mean ◽  
Post Menopausal

Objective: To determine the endometrial thickness at which endometrial sampling is indicated in asymptomatic post-menopausal women referred with thickened endometrium on ultrasound. Design: Retrospective case series Setting: Mercy Hospital for Women, Melbourne Population: Post-menopausal women without bleeding, undergoing hysteroscopy for thickened endometrium Methods: Logistic regression was used to examine the association between a range of variables and pre-malignant or malignant pathology and endometrial thickness Main outcome measures: The primary outcome was endometrial malignancy/pre-malignancy and its relation to endometrial thickness. Secondary outcomes focused on identifying additional predictors which may influence endometrial malignancy such as ultrasound findings, years since menopause, age, obesity, diabetes, and tamoxifen use. Results: A total of 404 postmenopausal women met the inclusion criteria for this study. The mean (SD) age of patients at presentation was 65 (9.09) years and the mean BMI was 29.86 kg/m2 (6.52). Of these women, nine (2.2%) were diagnosed with endometrial carcinoma and 7 (1.7%) had endometrial hyperplasia with atypia. The most common histopathological finding was of a benign endometrial polyp (153, 37.9%). When including hyperplasia with or without atypia in histopathology of interest, a cut-off of ≥9mm provides the greatest sensitivity (83.3%) and specificity (63.8%) for a diagnosis of pre-malignant or malignant pathology (classification accuracy of 64.8%; AUROC: 0.7358, 95%CI: 0.6439, 0.8278) in this cohort. Conclusions: Using an endometrial thickness of ≥9mm can be safely used as a cut-off for endometrial sampling in post-menopausal women without bleeding. Funding: Norman Beischer Medical Research Foundation, 2018 NBMRF Grant Keywords: Endometrial thickness, Post-menopausal, endometrial hyperplasia

scholarly journals Acute Haemoperitoneum: an unusual presentation of choriocarcinoma

2015 ◽  
Vol 9 (2) ◽  
pp. 112-115
Author(s):  
Nazlima Nargis ◽  
Md Iqbal Karim ◽  
Abu M Khuldhon
Keyword(s):  
Armed Forces ◽  
Reproductive Age ◽  
Unusual Presentation ◽  
Medical Emergency ◽  
Emergency Laparotomy ◽  
Medical College ◽  
Menopausal Women ◽  
Diagnostic Technology ◽  
Epithelial Tumour ◽  
Post Menopausal

Introduction: Choriocarcinoma is a highly malignant epithelial tumour arising from the trophoblastic tissue. It commonly occurs in women of reproductive age, rarely in post-menopausal women and in women under 20 years of age. Methods: The case was initially diagnosed as an unusual presentation of choriocarcinoma with acute haemoperitoneum due to perforation of uterus with lung metastasis. The patient an 18 yr old woman came with acute abdominal pain and signs of haemoperitoneum. Emergency laparotomy followed by hysterectomy was done. Subsequently patient took chemotherapy and improved. Conclusion: Acute haemoperitoneum is a medical emergency. So this case report emphasizes the need of sophisticated diagnostic technology for early diagnosis and successful management of the patient. Clinician should give more attention to unusal presentation of choriocarcinoma. DOI: http://dx.doi.org/10.3329/jafmc.v9i2.21850 Journal of Armed Forces Medical College Bangladesh Vol.9(2) 2013

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