Surface modification of PBT nonwoven fabrics used for blood filtration and their blood compatibility study

2012 ◽  
Vol 40 (5) ◽  
pp. 317-325 ◽  
Author(s):  
Ye Cao ◽  
Jiaxin Liu ◽  
Rui Zhong ◽  
Qing Yu ◽  
Hong Wang
Keyword(s):  
Surface Modification ◽  
Blood Compatibility ◽  
Compatibility Study ◽  
Nonwoven Fabrics

scholarly journals Chemical Modification as a Method of Improving Biocompatibility of Carbon Nonwovens

Materials ◽  
2021 ◽  
Vol 14 (12) ◽  
pp. 3198
Author(s):  
Justyna Frączyk ◽  
Sylwia Magdziarz ◽  
Ewa Stodolak-Zych ◽  
Ewa Dzierzkowska ◽  
Dorota Puchowicz ◽  
...  
Keyword(s):  
Surface Modification ◽  
Cellular Response ◽  
Fiber Surface ◽  
Thermal Conversion ◽  
Cartilage Tissue ◽  
Polar Component ◽  
Nonwoven Fabrics ◽  
Biological Compatibility ◽  
Starting Point

It was shown that carbon nonwoven fabrics obtained from polyacrylonitrile fibers (PAN) by thermal conversion may be modified on the surface in order to improve their biological compatibility and cellular response, which is particularly important in the regeneration of bone or cartilage tissue. Surface functionalization of carbon nonwovens containing C–C double bonds was carried out using in situ generated diazonium salts derived from aromatic amines containing both electron-acceptor and electron-donor substituents. It was shown that the modification method characteristic for materials containing aromatic structures may be successfully applied to the functionalization of carbon materials. The effectiveness of the surface modification of carbon nonwoven fabrics was confirmed by the FTIR method using an ATR device. The proposed approach allows the incorporation of various functional groups on the nonwovens’ surface, which affects the morphology of fibers as well as their physicochemical properties (wettability). The introduction of a carboxyl group on the surface of nonwoven fabrics, in a reaction with 4-aminobenzoic acid, became a starting point for further modifications necessary for the attachment of RGD-type peptides facilitating cell adhesion to the surface of materials. The surface modification reduced the wettability (θ) of the carbon nonwoven by about 50%. The surface free energy (SFE) in the chemically modified and reference nonwovens remained similar, with the surface modification causing an increase in the polar component (ɣp). The modification of the fiber surface was heterogeneous in nature; however, it provided an attractive site of cell–materials interaction by contacting them to the fiber surface, which supports the adhesion process.

Improving Blood Compatibility of Cardiovascular Devices by Surface Modification

2007 ◽  
pp. 801-804
Author(s):  
Nan Huang ◽  
Ping Yang ◽  
Yong Xiang Leng ◽  
Jun Ying Chen ◽  
Jin Wang ◽  
...  
Keyword(s):  
Surface Modification ◽  
Blood Compatibility ◽  
Cardiovascular Devices

Surface Modification of Copolyether-Urethane Catheters with Poly(Ethylene Oxide)

1989 ◽  
Vol 12 (6) ◽  
pp. 390-394 ◽  
Author(s):  
E. Brinkman ◽  
A. Poot ◽  
T. Beugeling ◽  
L. Van Der Does ◽  
A. Bantjes
Keyword(s):  
Surface Modification ◽  
Ethylene Oxide ◽  
Blood Compatibility ◽  
Angle Measurements ◽  
Fold Reduction ◽  
Contact Angle Measurements ◽  
Platelet Deposition ◽  
Poly Ethylene Oxide ◽  
Poly Ethylene

Pellethane 2363 80A catheters were modified with poly(ethylene oxide) in order to improve their blood compatibility. Contact angle measurements showed that Pellethane 2363 80A surfaces had increased wettability after this modification. The results of in vitro blood compatibility tests showed that surface modification with poly(ethylene oxide) resulted in a five-fold reduction of platelet deposition. Activation of coagulation was not affected.

Facile Surface Modification of Nitinol with Dopamine-Conjugated Hyaluronic Acid for Improving Blood Compatibility

2016 ◽  
Vol 6 (10) ◽  
pp. 780-787 ◽  
Author(s):  
Eugene Lih ◽  
So Yoon Chi ◽  
Tae Il Son ◽  
Yoon Ki Joung ◽  
Dong Keun Han
Keyword(s):  
Surface Modification ◽  
Hyaluronic Acid ◽  
Blood Compatibility

Facile surface modification of glass with zwitterionic polymers for improving the blood compatibility

2018 ◽  
Vol 5 (6) ◽  
pp. 065401 ◽  
Author(s):  
Lingling Zhang ◽  
Xiaojuan Chen ◽  
Pingsheng Liu ◽  
Jing Wang ◽  
Haomiao Zhu ◽  
...  
Keyword(s):  
Surface Modification ◽  
Blood Compatibility ◽  
Zwitterionic Polymers

AFM and Fractal Analysis of Biomaterial Microtopography

1998 ◽  
Vol 4 (S2) ◽  
pp. 926-927
Author(s):  
S. Jo ◽  
T. Li ◽  
K. Park
Keyword(s):  
Surface Modification ◽  
Self Assembly ◽  
Blood Compatibility ◽  
Carbon Chain ◽  
Atomic Force ◽  
Covalent Grafting ◽  
Biomaterial Surfaces ◽  
Poly Ethylene ◽  
Glass Surfaces

Although significant advances have been made in the development of biocompatible materials, currently available biomaterials still present a number of problems for in vivo applications. One of the attempts to improve the biocompatibility, especially blood-compatibility, of biomaterials has been surface modification. Typically, poly(ethylene glycol) (PEG), albumin, heparin, and phospholipid molecules are grafted to the surface to prevent protein adsorption and cell adhesion. We have been modifying biomaterial surfaces by covalent grafting of PEG and albumin. The control and modified surfaces were examined using an atomic force microscope (AFM). In this study, we examined the surface topography changes by surface modification using PEO grafting to glass as a model system.Glass surfaces were modified with PEO using (N-triethoxysilylpropyl)-Omonomethoxy PEG urethane (PEG-Si), a PEG derivative containing a hydrophobic carbon chain and triethoxysilyl group at one end of the PEG chain. The presence of the hydrophobic carbon chain allowed self-assembly on the surface and triethoxysilyl resulted in covalent bonding to glass surfaces

Sign in / Sign up

Export Citation Format

Share Document