scholarly journals Alterations of bone tissue metabolism in celiac disease

2020 ◽  
Vol 1 (10) ◽  
pp. 90-95
Author(s):  
E. A. Semenova ◽  
L. S. Оrеshkо ◽  
A. V. Shomin
Keyword(s):  
Celiac Disease ◽  
Bone Tissue ◽  
Clinical Case ◽  
Economic Importance ◽  
Point Of View ◽  
Secondary Osteoporosis ◽  
Skeletal System ◽  
Atypical Form ◽  
Tissue Metabolism

The problem of osteopenia and early osteoporosis in celiac disease has a great socio-economic importance and is an important area of medicine, primarily from the point of view of a diagnostic search and treatment. This article presents a clinical case of the atypical form of celiac disease with a lesion of skeletal system, osteopenia and secondary osteoporosis without symptoms of intestinal dyspepsia and obvious signs of malabsorption. The basic mechanisms for the development of osteopenic complications in celiac disease are described, and recommendations for follow-up and treatment of such patients are presented.

scholarly journals Trefoil System for the Treatment of Mandibular Edentulism: A Case Report with 30 Months Follow-Up

2020 ◽  
Vol 2020 ◽  
pp. 1-6
Author(s):  
Andrea E. Borgonovo ◽  
Simone L. M. Galbiati ◽  
Dino Re
Keyword(s):  
Case Report ◽  
Clinical Case ◽  
Good Health ◽  
Point Of View ◽  
Health Conditions ◽  
Good Level ◽  
Surgical Guides ◽  
Fixed Prosthesis ◽  
Functional Point

The purpose of this work is to describe a clinical case of full-arch mandible rehabilitation with a fixed prosthesis on three implants. The chosen protocol is the Trefoil system by Nobel (Nobel Biocare, Zurich, Switzerland) that allows to realize a mandibular fixed rehabilitation on three particularly designed fixtures through the use of prefabricated surgical guides and a preassembled bar on which the prosthesis is built. Both surgical and prosthetic procedures were completed without complications, and after 30 months, the rehabilitations are in good health conditions. The patient is able to maintain a good level of hygiene and is satisfied with the work from an aesthetic and functional point of view.

Circulating matrix metaloproteinases as biomarkers in colorectalcancer

2020 ◽  
Vol 99 (9) ◽  
Keyword(s):  
Colorectal Cancer ◽  
Tumor Markers ◽  
Point Of View ◽  
Tissue Inhibitors ◽  
Natural Tissue

The aim of this research is to offer comprehensive point of view related to perspective tumor markers called matrix metaloproteinases and their natural tissue inhibitors. Those markers are potentially useable mainly in postoperative follow-up in patients with colorectal cancer.

Thyroidectomy in a patient with a giant multinodular nontoxic cervical retrosternal goiter

2020 ◽  
pp. 97-99
Author(s):  
U. V. Kukhtenko ◽  
O. A. Kosivtsov ◽  
L. A. Ryaskov ◽  
E. I. Abramian
Keyword(s):  
Surgical Treatment ◽  
Clinical Case ◽  
Clinical Signs ◽  
Disease Relapse ◽  
Cardiac Pathology ◽  
Nontoxic Goiter ◽  
Retrosternal Goiter

A clinical case of successful surgical treatment of a patient with a giant cervical retrosternal nontoxic goiter with severe cardiac pathology is presented. Thyroidectomy from cervical access without sternotomy was performed. At the follow-up examination 5 months after the operation, instrumental and clinical signs of disease relapse were not detected.

scholarly journals Rationale for Timing of Follow-Up Visits to Assess Gluten-Free Diet in Celiac Disease Patients Based on Data Mining

Nutrients ◽  
2021 ◽  
Vol 13 (2) ◽  
pp. 357
Author(s):  
Alfonso Rodríguez-Herrera ◽  
Joaquín Reyes-Andrade ◽  
Cristina Rubio-Escudero
Keyword(s):  
Data Mining ◽  
Celiac Disease ◽  
Cultural Context ◽  
Gluten Free Diet ◽  
Gluten Free ◽  
Adherence To Diet ◽  
And Gender ◽  
Few Data

The assessment of compliance of gluten-free diet (GFD) is a keystone in the supervision of celiac disease (CD) patients. Few data are available documenting evidence-based follow-up frequency for CD patients. In this work we aim at creating a criterion for timing of clinical follow-up for CD patients using data mining. We have applied data mining to a dataset with 188 CD patients on GFD (75% of them are children below 14 years old), evaluating the presence of gluten immunogenic peptides (GIP) in stools as an adherence to diet marker. The variables considered are gender, age, years following GFD and adherence to the GFD by fecal GIP. The results identify patients on GFD for more than two years (41.5% of the patients) as more prone to poor compliance and so needing more frequent follow-up than patients with less than 2 years on GFD. This is against the usual clinical practice of following less patients on long term GFD, as they are supposed to perform better. Our results support different timing follow-up frequency taking into consideration the number of years on GFD, age and gender. Patients on long term GFD should have a more frequent monitoring as they show a higher level of gluten exposure. A gender perspective should also be considered as non-compliance is partially linked to gender in our results: Males tend to get more gluten exposure, at least in the cultural context where our study was carried out. Children tend to perform better than teenagers or adults.

scholarly journals Changes in Age at Diagnosis and Nutritional Course of Celiac Disease in the Last Two Decades

Nutrients ◽  
2020 ◽  
Vol 12 (1) ◽  
pp. 156 ◽  
Author(s):  
Mónica Villanueva ◽  
Amaya Oyarzún ◽  
Bárbara Leyton ◽  
Mónica González ◽  
Elizabeth Navarro ◽  
...  
Keyword(s):  
Celiac Disease ◽  
Nutritional Status ◽  
Gastrointestinal Symptoms ◽  
Failure To Thrive ◽  
Age At Diagnosis ◽  
Pediatric Hospitals ◽  
Geographical Variations ◽  
Number Of Patients ◽  
Antiendomysial Antibodies

The frequency of celiac disease (CD) has increased along time, with relevant changes reported in geographical variations, clinical presentation and nutritional repercussions. In recent years, some celiac patients are presenting overweight/obesity, but it is unclear how frequent this is and to what extent undernutrition remains a concern. This is relevant because CD tends to be overlooked in overweight patients. With this in mind, we assessed age at diagnosis, clinical characteristics and nutritional status of 155 celiac patients diagnosed between 1994–2017 in four pediatric hospitals in Santiago, Chile. Since 2003, the number of patients diagnosed has increased (p < 0.0033), coinciding with antitransglutaminase and antiendomysial antibodies becoming available to public health systems. In 2000, 4.5% of patients were asymptomatic at diagnosis, suggesting that active search is not routinely applied. Gastrointestinal symptoms plus failure to thrive were significantly more frequent under 2 years (p = 0.0001). Nutritional status has improved at diagnosis and during follow up, but undernutrition remains more frequent in children <2 and <5 years (p < 0.002 and p < 0.0036, respectively). Overweight at diagnosis was reported in 2002 and obesity in 2010. After initiating treatment, since 2010, patients changing from undernourishment to overweight has sometimes been observed after only 6 months on a gluten-free diet.

scholarly journals Application of Deamidated Gliadin Antibodies in the Follow-Up of Treated Celiac Disease

PLoS ONE ◽  
2015 ◽  
Vol 10 (8) ◽  
pp. e0136745 ◽  
Author(s):  
Luc de Chaisemartin ◽  
Tchao Meatchi ◽  
Georgia Malamut ◽  
Fahima Fernani-Oukil ◽  
Frédérique Hosking ◽  
...  
Keyword(s):  
Celiac Disease ◽  
Gliadin Antibodies

DIRECTIONS FOR ENHANCING THE DEVELOPMENT OF CITRUS FRUIT GROWING IN AZERBAIJAN

2021 ◽  
Vol 1 (10) ◽  
pp. 167-173
Author(s):  
Nurida Аlish Gasimova ◽  
Keyword(s):  
Citrus Fruit ◽  
Economic Importance ◽  
Point Of View ◽  
Raw Material ◽  
Current State ◽  
Citrus Production ◽  
Fruit Growing

The increase in citrus production is of particular economic importance both from the point of view of meeting the demand of the population for these products, and from the point of view of its use as an industrial raw material. The article studies and analyzes the current state of citrus cultivation in Azerbaijan, the possibilities of increasing their production; relevant suggestions and recommendations are made.

scholarly journals Descriptive Study of the Different Tools Used to Evaluate the Adherence to a Gluten-Free Diet in Celiac Disease Patients

Nutrients ◽  
2018 ◽  
Vol 10 (11) ◽  
pp. 1777 ◽  
Author(s):  
Luis Rodrigo ◽  
Isabel Pérez-Martinez ◽  
Eugenia Lauret-Braña ◽  
Adolfo Suárez-González
Keyword(s):  
Celiac Disease ◽  
Multidisciplinary Approach ◽  
Descriptive Study ◽  
Duodenal Mucosa ◽  
Gluten Free Diet ◽  
Gluten Free ◽  
Autoimmune Process ◽  
Duodenal Biopsies

Celiac disease (CD) is a genetically conditioned autoimmune process that appears in susceptible people. It can affect people of any age, and slightly predominates in females. It has a fairly homogenous global distribution, with an average prevalence of 1–2%, the frequency having increased in recent decades. The only effective treatment is a strict and permanent gluten-free diet (GFD), although the level of compliance is poor, at about 50% of cases. To monitor the effectiveness of the GFD, several procedures involving various approaches are employed: (a) Periodic visits by expert Nutritionists; (b) Clinical follow-up; (c) Serological time controls of specific antibodies; (d) Serial endoscopies with collection of duodenal biopsies; (e) Use of structured questionnaires; and (f) Determination of gluten peptides derived from gluten in faeces and/or urine. All of these procedures are useful when applied, alone or in combination, depending on the cases. Some patients will only need to consult to their doctors, while others will require a multidisciplinary approach to assess their compliance with the GFD. In children, normalization of duodenal mucosa was achieved in 95% of cases within two years, while it is more delayed in adults, whose mucosa take longer time (3–5 years) to heal completely.

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