SOME MOLECULAR ASPECTS OF PLANT PEROXIDASE BIOSYNTHETIC STUDIES

2020 ◽  
Author(s):  
Lungwani Muungo

The early history of research on peroxidase is most capably reviewed bySaunders et al (67). The first color reaction of biological material withguaiacum as substrate was noted in 1809, but the term peroxidase was usedfor the first time nearly a century later for an enzyme isolated from horseradish.In fact, peroxidase is widely distributed in the plant kingdom and also occurs in the animal kingdom. Many of the spectral aspects of this hemoproteinand its reaction products have been described in the above-mentioned textand elsewhere (e.g. 23). Different types of peroxidases were recognized, andan ever-increasing number of functions were ascribed to them, particularly inplant physiology (31). Therefore, while the basic chemical reactions ofperoxidase (E. C . 1.1 1.1. 7) are well established, namely that of the peroxidaticcycle involving H202 and a large array of hydrogen donors (23), the questionsof how its many isozymes function (31) and how its action in differentiation iscontrolled (68) remain largely unanswered. I do not review all publications onthese topics here. A comprehensive tabulation has appeared recently (31).Instead, I offer a critical review of certain aspects of peroxidase in terms ofstructure and biosynthesis.

1989 ◽  
Vol 84 ◽  
pp. 177-185
Author(s):  
R.W.V. Catling ◽  
R.E. Jones

Two vases, a cup and an oinochoe, from Arkesine in south-west Amorgos are published for the first time. It is argued that both are probably Middle Protogeometric, one an import from Euboia, the other from the south-east Aegean; chemical analysis supports both attributions. Their implications for the early history of Amorgos are discussed.


The Library ◽  
2020 ◽  
Vol 21 (1) ◽  
pp. 89-97
Author(s):  
Karen Thomson

Abstract In the standard scholarly work, The Library of Isaac Newton published by CUP in 1978, John Harrison makes two significant assumptions about the library’s early history which are incorrect. This paper highlights the necessary revisions, including the unnoticed role played by Mrs Jane Musgrave, Jane Austen’s godmother, in the library’s preservation. It also proposes for the first time a plausible reason why John Huggins, Warden of the Fleet Prison, bought the library from the executors immediately after Newton’s death.


2020 ◽  
Vol 20 (1) ◽  
Author(s):  
Michiru Sawahata ◽  
Noritaka Sakamoto ◽  
Hideaki Yamasawa ◽  
Yuki Iijima ◽  
Hirotoshi Kawata ◽  
...  

Abstract Background The number of reports on sarcoidosis complicated by hypersensitivity pneumonitis (HP) is limited, and most describe cases complicated by chronic bird-related HP. Here, we present for the first time a case with Propionibacterium acnes-associated sarcoidosis complicated by acute bird-related HP. Case presentation A 62-year-old man with a past medical history of sarcoidosis was admitted to our department, and chest computed tomography showed diffuse ground-glass opacities, which appeared as he rapidly increased the number of pigeons he kept for a competition. Random transbronchial lung biopsy revealed well-formed non-caseating epithelioid granulomas, which contained positively stained substances on immunohistochemistry using the PAB antibody, a specific monoclonal antibody against P. acnes lipoteichoic acid. Poorly formed non-caseating granulomas without positively stained substances were also detected. Conclusion We describe the successful identification of this exceptionally rare case of sarcoidosis complicated by acute bird-related HP in which two morphologically and immunohistologically different types of granulomas were present in the same lung.


Science ◽  
1941 ◽  
Vol 93 (2413) ◽  
pp. 305-306 ◽  
Author(s):  
C. B. DAVENPORT

2015 ◽  
Vol 2 (4) ◽  
pp. 210-213
Author(s):  
Gina Lupașcu ◽  
Georgiana Radu ◽  
Cristina Veronica Andreescu ◽  
Alexandra Bolocan

Selman Waksman is an important name that introduced for the first time the idea of some natural compounds with visible effects in treatment of diseases called- antibiotics. Its continuous and irrational utilization has been proven to make the body resistant to a future need of the antibiotic administered. This aspect did not stop the studies to shown the importance of this biosynthesized medicines in prophylaxis of surgery. During the years there were identified a lot of these natural compounds with positive results in different types of surgery. The purpose of this article is to bring to attention the evolution of antibiotics during the years, especially in surgery field, how its usage influenced the prophylaxis and which are the main principles to be respected in administration of antibiotics.


2021 ◽  
Vol 17 (8) ◽  
pp. 20210221
Author(s):  
Pedro Andrade ◽  
Miguel Carneiro

Pterins are one of the major sources of bright coloration in animals. They are produced endogenously, participate in vital physiological processes and serve a variety of signalling functions. Despite their ubiquity in nature, pterin-based pigmentation has received little attention when compared to other major pigment classes. Here, we summarize major aspects relating to pterin pigmentation in animals, from its long history of research to recent genomic studies on the molecular mechanisms underlying its evolution. We argue that pterins have intermediate characteristics (endogenously produced, typically bright) between two well-studied pigment types, melanins (endogenously produced, typically cryptic) and carotenoids (dietary uptake, typically bright), providing unique opportunities to address general questions about the biology of coloration, from the mechanisms that determine how different types of pigmentation evolve to discussions on honest signalling hypotheses. Crucial gaps persist in our knowledge on the molecular basis underlying the production and deposition of pterins. We thus highlight the need for functional studies on systems amenable for laboratory manipulation, but also on systems that exhibit natural variation in pterin pigmentation. The wealth of potential model species, coupled with recent technological and analytical advances, make this a promising time to advance research on pterin-based pigmentation in animals.


Radiocarbon ◽  
1997 ◽  
Vol 40 (2) ◽  
pp. 583-589 ◽  
Author(s):  
Alexander L. Alexandrovskiy ◽  
Johannes Van Der Plicht ◽  
Nikolay Krenke ◽  
Olga Chichagova ◽  
Nikolai Kovaliukh ◽  
...  

For the first time, a series of 14C dates has been obtained for samples from the archaeological excavations in Red Square, the historical center of Moscow. The remains of burned dwellings from the bottom of the cultural layer were dated as well as dispersed charcoal from the underlying plough soil. The results correspond to a 200-yr time interval and prove that arable activity at the site began as early as the late 11th century ad. The field belonged to Moscow itself or to rural settlements nearby. The oldest dwelling was built ca. the late 12th–early 13th century ad.


1977 ◽  
Vol 36 ◽  
pp. 421-445 ◽  
Author(s):  
J.B. Zirker

Coronal holes are regions of depressed density and temperature in the inner corona that coincide with open magnetic field lines. They were recognized for many years on eclipse photographs, but real understanding of their importance began to emerge only after data from rocket and satellite observations were analyzed. Wilson (1976) has summarized the early history of research on coronal holes.


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