scholarly journals Preregistered replication of “Sick body, vigilant mind: The biological immune system activates the behavioral immune system”

2020 ◽  
Author(s):  
Joshua M. Tybur ◽  
Benedict C Jones ◽  
Lisa Marie DeBruine ◽  
Joshua Ackerman ◽  
Vanessa Fasolt

The tendency to attend to and avoid cues to pathogens varies across individuals and contexts. Researchers have proposed that this variation is partially driven by immunological vulnerability to infection, though support for this hypothesis is equivocal. One key piece of evidence finds that recently ill participants – who may have a reduced ability to combat subsequent infection – allocate more attention to faces with infectious disease cues than do participants who have not recently been ill. The current manuscript reports a direct replication of this study using a sample of 402 individuals from the University of Michigan, the University of Glasgow, and VU Amsterdam – over four times the sample size of the original study. No effect of illness recency on attentional bias for disfigured faces emerged. Though not supporting the original finding, this replication provides suggestions for future directions for research on the psychological underpinnings of pathogen avoidance.

2020 ◽  
Vol 31 (11) ◽  
pp. 1461-1469 ◽  
Author(s):  
Joshua M. Tybur ◽  
Benedict C. Jones ◽  
Lisa M. DeBruine ◽  
Joshua M. Ackerman ◽  
Vanessa Fasolt

The tendency to attend to and avoid cues to pathogens varies across individuals and contexts. Researchers have proposed that this variation is partially driven by immunological vulnerability to infection, though support for this hypothesis is equivocal. One key piece of evidence (Miller & Maner, 2011) shows that participants who have recently been ill—and hence may have a reduced ability to combat subsequent infection—allocate more attention to faces with infectious-disease cues than do participants who have not recently been ill. The current article describes a direct replication of this study using a sample of 402 individuals from the University of Michigan, the University of Glasgow, and Vrije Universiteit Amsterdam—more than 4 times the sample size of the original study. No effect of illness recency on attentional bias for disfigured faces emerged. Though it did not support the original finding, this replication provides suggestions for future research on the psychological underpinnings of pathogen avoidance.


2018 ◽  
Vol 12 (2) ◽  
pp. e12371 ◽  
Author(s):  
Joshua M. Ackerman ◽  
Sarah E. Hill ◽  
Damian R. Murray

2011 ◽  
Vol 22 (12) ◽  
pp. 1467-1471 ◽  
Author(s):  
Saul L. Miller ◽  
Jon K. Maner

Activation of the behavioral immune system has been shown to promote activation of the biological immune system. The current research tested the hypothesis that activation of the biological immune system (as a result of recent illness) promotes activation of the behavioral immune system. Participants who had recently been ill, and had therefore recently experienced activation of their biological immune system, displayed heightened attention to (Study 1) and avoidance of (Study 2) disfigured individuals—cognitive and behavioral processes reflecting activation of the behavioral immune system. These findings shed light on the interactive nature of biological and psychological mechanisms designed to help people overcome the threat of disease.


Author(s):  
Julian M. Saad ◽  
James O. Prochaska

AbstractThe understanding that immunity could be strengthened in the general population (e.g., through vaccine interventions) supported global advances upon acute infectious disease epidemics in the eighteenth, nineteenth, and twentieth centuries. However, in the twenty-first century, global populations face chronic disease epidemics. Research demonstrates that diseases largely emerge from health risk behavior. The understanding of how health behavior, like the biological immune system, can be strengthened in the general population, could support advances in the twenty-first century. To consider how health behavior can be strengthened in the general population, the authors present a theoretical model of population health behavior. The model operationalizes health behavior as a system of functions that, like the biological immune system, exists in each member of the population. Constructs are presented that operationalize the specific decisions and habits that drive health behavior and behavior change in the general population. The constructs allow the authors to present parallels (1) among existing behavior change theories and (2) between the proposed system and the biological immune system. Through these parallels, the authors introduce a model and a logic of population-level health behavior change. The Adaptive Behavioral Immune System is an integrative model of population health behavior.


Author(s):  
Daniel J. Wallace ◽  
Janice Brock Wallace

In medical school, students learn about the human body by organ system. They spend a few weeks on the heart, then the lung, followed by the gastrointestinal tract. Eventually the whole body is covered. One of the fascinating developments in the last decade has been the functional linkage and new connections of seemingly diverse body systems. Fibromyalgia research finally hit its stride when important studies connected the nervous system, the endocrine (hormone) system, and the immune system. This enabled physicians to devise improved strategies to help fibromyalgia patients. Basic background information provided in this chapter will be expanded upon in later parts of the book when we review treatments. Within the brain is a small region known as the hypothalamus. It makes releasing hormones that travel down a short path to the pituitary gland, which makes stimulating hormones. The stimulating hormones send signals to tissues where hormones are manufactured for specialized functions. Table 3 and Figure 9 show how thyroid, cortisol, insulin, breast milk, and growth hormone are made along the hypothalamic-pituitary axis and the hypothalamic-pituitary-adrenal (HPA) axis. We have already mentioned that emotional stress can bring on or aggravate fibromyalgia. At the National Institutes of Health and the University of Michigan, studies have firmly established some of the factors important in this relationship. The role of corticotropin-releasing hormone (CRH), the precursor or ancestor of the steroid known as cortisol, has been the focus of much of this work. Even though CRH levels are normal in fibromyalgia, CRH responses (stress responses) to different forms of stimulation are blunted. CRH has many important interactions other than leading to the production of steroids. Its expression can be increased by stress, serotonin, and estrogen. Endorphins promote the secretion of CRH. Decreased sympathetic nervous system activity in the adrenal glands and substance P, as well as nitric oxide, can turn off CRH production. Rats with abnormally low stress responses develop many of the features we associate with fibromyalgia. How do these interrelationships translate into a fibromyalgia patient’s feeling of being unwell? The answer is not clear. However, these studies suggest that fibromyalgia patients do not respond normally to acute stress and do not release enough adrenalin.


2019 ◽  
Vol 17 (1) ◽  
pp. 147470491982685 ◽  
Author(s):  
Tingting Ji ◽  
Joshua M. Tybur ◽  
Mark van Vugt

Researchers have proposed that intergroup prejudice is partially caused by behavioral immune system mechanisms. Across four studies (total N = 1,849), we used both experimental (pathogen priming) and individual differences (pathogen disgust sensitivity [PDS]) approaches to test whether the behavioral immune system influences prejudice toward immigrants indiscriminately (the generalized out-group prejudice hypothesis) or specifically toward immigrants from a pathogen-rich ecology (the origin-specific out-group prejudice hypothesis). Internal meta-analyses lend some support to both hypotheses. At the experimental level, pathogen primes had no effect on attitudes toward origin-unspecified immigrants or immigrants from a pathogen-rich ecology. At the individual differences level, PDS has a unique negative effect on comfort with immigrants from pathogen-rich ecologies but not on comfort with immigrants from unspecified ecologies. However, pathogen disgust sensitivity was negatively related to the decision to allow entry to both origin-unspecified immigrants and immigrants from a pathogen-rich ecology.


2019 ◽  
Author(s):  
TCU Hill Lab

Disgust and the immune system function as protections against the persistent threat of pathogen presence. However, the degree to which individuals invest in pathogen-avoidance (i.e., disgust) versus pathogen-management (i.e., the immune system) strategies should vary based on one’s ability to exercise control over their contact with potential sources of infection. We test this hypothesis across four studies. Findings reveal that when perceived or experimentally manipulated ability to control pathogen exposure was low, individuals exhibited decreased disgust sensitivity. Moreover, lower perceived control over pathogen exposure predicted higher basal immunological activity, which in turn predicted decreased behavioral efforts to avoid potentially pathogenic stimuli. Findings further reveal that inhibiting basal inflammatory activity (via aspirin administration) leads to a compensatory increase in disgust sensitivity, providing evidence for a causal relationship between these two variables. By providing novel insights into how one’s control over pathogen exposure influences disgust sensitivity and immune system activity, the current research poses an important contribution to the literature on disgust, pathogen avoidance, and the immune system.


2020 ◽  
Vol 15 (3) ◽  
Author(s):  
Mitch Brown ◽  
Donald F. Sacco

To reduce disease transmission through interpersonal contact, humans have evolved a behavioral immune system that facilitates identification and avoidance of pathogens. One behavioral strategy in response to pathogenic threat is the adoption of interpersonal reticence. However, reticence may impede status acquisition. This program of research tested whether activating pathogen-avoidant motives through priming fosters reticence related to status, namely disinterest in pursuing a group leadership position (Study 1) or disinterest in accepting a group leadership position bestowed onto them (Study 2). Individuals high in germ aversion were particularly interested in pursuing leadership as a form of status, with disease salience unexpectedly heightening status motives among those low in germ aversion. Furthermore, those high in perceived infectability reported reluctance for high-status positions, although disease salience heightened interest in accepting such positions. We contextualize findings by identifying dispositional and situational factors that foster individuals to invoke motivational tradeoffs.


Author(s):  
Amelia Díaz ◽  
Ángela Beleña ◽  
Jesús Zueco

Background: The study of the immune system has been approached using two separate paths, the biological immune system and the behavioral immune system. Recently, Gangestad and Grebe proposed a unique integrated compensatory immune system, where both systems work together and one of them could compensate for the other when necessary. However, few studies have confirmed the existence of this integrated compensatory immune system. Our study represents an attempt to explore the existence of this unique immune system, investigating if the behavioral immune system variables increase when the biological immune system weakens with age. Material and Methods. The cross-sectional design study was made up of a final sample of 1108 participants (45.2% men and 54.2 women) aged 18–64 years. The younger group (18–21 years) was made up of students, whilst the older groups (22 to 64 years) were composed by their relatives and acquaintances, following the snow ball process. The participants completed the Perceived Vulnerability to Disease Questionnaire that assesses perceived infectability and germ aversion. Correlations, analyses of variance (ANOVAs), and independent group comparisons were performed. These analyses showed the relationships between the variables studied, the effects of age and gender in perceived infectability and germ aversion, and the differences that perceived infectability and germ aversion presented in different age-groups separated by gender. Results: A pattern emerged where germ aversion increases as both men and women get older, but perceived infectability decreases up to the age of 50, and then it increases in women from that age onward. Gender differences are only significant in younger participants, with women having higher scores than men in both variables. Conclusion: The results partially support the existence of a unique integrated compensatory biological/behavioral immune system.


2020 ◽  
Author(s):  
Anastasia Makhanova ◽  
Melissa A. Shepherd

People possess psychological processes that help them avoid pathogens, which is particularly important when novel infectious diseases (e.g., COVID-19) spread through the population. Across two studies we examined whether trait pathogen avoidance (operationalized as perceived vulnerability to disease; PVD) was linked with responses to COVID-19 and preventative behaviors. In Study 1, PVD was positively associated with stronger reactions to the threat of COVID-19, including increased anxiety, perceptions that people should alter their typical behavior, as well as reported importance of engaging in proactive and social distancing behaviors. In Study 2, PVD was again associated with increased anxiety, as well as more vigilant behavior when grocery shopping, fewer trips to the store, and fewer face-to-face interactions. These associations remained significant when controlling for the Big-5 personality traits. Although the two subscales of PVD (germ aversion and perceived infectability) were often parallel predictors, several differences between the subscales emerged. Germ aversion may be more associated with behaviors whereas perceived infectability with vigilance.


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