scholarly journals Dose-response association between daily objective physical activity and C-reactive Protein in a representative national sample of adults with self-reported diagnosed arthritis or fibromyalgia

2019 ◽  
Author(s):  
Celia Kingsbury ◽  
Antony Karelis ◽  
Gabriel Hains-Monfette ◽  
Paquito Bernard
Keyword(s):  
Physical Activity ◽  
Dose Response ◽  
High Sensitivity ◽  
National Sample ◽  
Additive Models ◽  
Step Count ◽  
Response Patterns ◽  
C Reactive Protein ◽  
Reactive Protein ◽  
Education Levels

Objective: Examine the transversal association between objectively measured physical activity (PA) and sedentary time (SED-time) with high sensitivity C-Reactive Protein (hsCRP) levels in adults with arthritis and fibromyalgia. We also investigated the dose of PA that was associated with lower clinical levels of hsCRP (< 3 mg/L).Design: Observational designSetting: Canadian Health Measures Survey (CHMS) cycle 1 to 3 (2007 – 2012)Participants: CHMS respondents with self-reported diagnosed arthritis or fibromyalgia from the CHMS cycle 1 to 3 (2007 – 2012)Main Outcome Measure: Generalized adjusted additive models were used to explore the shape of the association between hsCRP, daily PA, step count and SED-time. HsCRP was measured with blood samples. PA, number of steps and SED-time were objectively assessed using an Actical accelerometer. Results: Daily moderate to vigorous PA and step count were significantly associated with lower hsCRP levels, but daily LPA and SED-time were not associated with hsCRP levels, even after controlling for age, sex, daily smoking, body mass index (BMI), household income, level of education levels, marital status, work year and accelerometer wear time and season of accelerometer. Non-linear dose-response patterns were observed between daily moderate to vigorous PA as well as step count with hsCRP levels. Optimal and specific doses of daily minutes of moderate to vigorous PA and daily steps were independently related to lower hsCRP in adults with arthritis and fibromyalgia.Conclusions: Daily MVPA and step count were associated with hsCRP levels that were below the clinical threshold. Given the positive outcomes of PA on health, adults with arthritis and fibromyalgia may benefit from these specific recommendations.

scholarly journals Dose response association of objective physical activity with mental health in a representative national sample of adults: a cross-sectional study

2018 ◽  
Author(s):  
Paquito Bernard ◽  
Isabelle Doré ◽  
Romain Ahmed Jérôme ◽  
Gabriel Hains-Monfette ◽  
Kingsbury ◽  
...  
Keyword(s):  
Mental Health ◽  
Physical Activity ◽  
Dose Response ◽  
Sedentary Time ◽  
Generalized Additive Models ◽  
National Sample ◽  
Additive Models ◽  
Curvilinear Relationship ◽  
Cross Sectional ◽  
Representative National Sample

Although higher physical activity (PA) levels are associated with better mental health, previous findings about the shape of the dose–response relationship between PA and mental health are inconsistent. Furthermore, this association may differ according to sedentary levels. We investigated the cross-sectional dose-response associations between objectively measured PA and mental health in a representative national sample of adults. We also examined whether sedentary time modified the PA - mental health associations. Based on 2007-2013 Canadian Health Measures Survey data, PA and sedentary time were measured using accelerometry among 8150 participants, aged 20 to 79 years. Generalized additive models with a smooth function were fitted to examine associations between minutes per day of moderate and vigorous PA (MVPA), light PA (LPA), daily steps (combined or not with sedentary time) and self-rated mental health. A significant curvilinear relationship between average daily minutes of MVPA and mental health was observed, with increasing benefits up to 50 minutes/day. For LPA, a more complex shape (monotonic and curvilinear) was found. For daily steps, inverted U-shaped curve suggested increasing benefits until a plateau between 5000 and 16000 steps. The MVPA-LPA combination was significantly associated with mental health but with a complex pattern. The tested PA-sedentary time combinations showed that increasing sedentary time decreased the positive PA-mental health associations. Non-linear dose-response patterns between the PA modalities and self-reported mental health were observed. Optimal doses of daily minutes of MVPA, LPA, MVPA combined with LPA and daily steps are independently associated with better mental health in adults. The results also suggest that PA-mental health associations could be hampered by daily sedentary time.

scholarly journals Kadar High Sensitivity C-Reactive Protein Berkaitan dengan Lingkar Pinggang pada Lansia

2021 ◽  
Vol 8 (1) ◽  
pp. 21
Author(s):  
Deny Yudi Fitranti ◽  
Bunga Syifarahmi ◽  
Martha Ardiaria ◽  
Nurmasari Widyastuti
Keyword(s):  
Physical Activity ◽  
Vitamin D ◽  
International Physical Activity Questionnaire ◽  
High Sensitivity ◽  
C Reactive Protein ◽  
Cross Sectional ◽  
Reactive Protein ◽  
Consecutive Sampling ◽  
Hs Crp ◽  
Activity Questionnaire

<p>Proses penuaan mempengaruhi peningkatan distribusi lemak abdominal dengan indikator lingkar pinggang (LP) dan rasio lingkar pinggang panggul (RLPP). Penimbunan lemak abdominal menyebabkan disfungsi jaringan adiposa sehingga mempengaruhi biomarker proinflamasi yaitu kadar serum <em>high-sensitivity C-reactive Protein</em> (hs-CRP). Penelitian bertujuan untuk mengetahui hubungan LP dan RLPP dengan kadar hs-CRP lansia wanita. Rancangan penelitian <em>cross sectional</em> pada 53 subjek dipilih secara <em>consecutive sampling</em>. Antropometri yang diukur adalah LP dan RLPP. Pengukuran kadar serum hs-CRP dianalisis dengan metode <em>enyme-linked immunosorbent assay</em> (ELISA). Wawancara yang dilakukan yaitu data diri, asupan, aktivitas fisik, dan riwayat konsumsi obat. Data asupan diperoleh dengan metode <em>food recall</em> 3x24 jam. Aktivitas fisik diperoleh menggunakan <em>International Physical Activity Questionnaire</em> (IPAQ). Analisis data digunakan uji korelasi <em>Spearman</em>. Hasil penelitian menunjukkan bahwa persentase LP pada lansia wanita yang berisiko sebesar 90,6%, RLPP yang berisiko sebesar 98,1%, dan kadar hs-CRP tinggi sebesar 30,2%. Terdapat hubungan positif antara LP dengan kadar serum hs-CRP (r=0,417 ; p=0,002). Dalam penelitian ini RLPP, aktivitas fisik, asupan energi, karbohidrat, protein, lemak, serat, vitamin A, vitamin C, vitamin D,vitamin E, dan selenium tidak berkorelasi dengan kadar hs-CRP. Simpulan penelitian ini adalah LP berkorelasi positif dengan kadar serum hs-CRP, namun RLPP tidak berkorelasi dengan kadar serum hs-CRP</p>

scholarly journals Amount of physical activity necessary for a normal level of high-sensitivity C-reactive protein in ELSA-Brasil: a cross-sectional study

2020 ◽  
Vol 138 (1) ◽  
pp. 19-26
Author(s):  
Ciro Oliveira Queiroz ◽  
Francisco Pitanga ◽  
Paulo Andrade Lotufo ◽  
Maria Del Carmen Bisi Molina ◽  
Estela Maria Leão de Aquino ◽  
...  
Keyword(s):  
Physical Activity ◽  
Normal Level ◽  
High Sensitivity ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
C Reactive Protein ◽  
Cross Sectional ◽  
Reactive Protein

scholarly journals Physical Activity and High-Sensitivity C-Reactive Protein

2009 ◽  
Vol 36 (1) ◽  
pp. 56-62 ◽  
Author(s):  
Darcy S. Majka ◽  
Rowland W. Chang ◽  
Thanh-Huyen T. Vu ◽  
Walter Palmas ◽  
Dominic F. Geffken ◽  
...  
Keyword(s):  
Physical Activity ◽  
High Sensitivity ◽  
C Reactive Protein ◽  
Reactive Protein

Homocysteine and C-Reactive Protein Levels Are Associated With Frailty in Older Spaniards: The Toledo Study for Healthy Aging

2019 ◽  
Vol 75 (8) ◽  
pp. 1488-1494 ◽  
Author(s):  
Nuria Álvarez-Sánchez ◽  
Ana Isabel Álvarez-Ríos ◽  
Juan Miguel Guerrero ◽  
Francisco José García-García ◽  
Leocadio Rodríguez-Mañas ◽  
...  
Keyword(s):  
Physical Activity ◽  
Healthy Aging ◽  
High Sensitivity ◽  
Inflammation Markers ◽  
C Reactive Protein ◽  
Physical Decline ◽  
Protein Levels ◽  
Reactive Protein ◽  
Risk Of Death ◽  
Age Related

Abstract High-sensitivity C-reactive protein (hsCRP) and homocysteine (Hcy) are inflammation markers but are also related to cardiovascular diseases, disability, or higher risk of death. Although inflammation is considered to be associated with frailty, data regarding the association between hsCRP or Hcy and frailty are controversial or scarce, especially with respect to their association with prefrailty. Thus, our objective was to study the association of hsCRP and Hcy with prefrailty and frailty in 1,211 Spanish men and women aged 65–98 years from the Toledo Study for Healthy Aging (TSHA) cohort, classified according to Fried’s criteria. Hcy was independently associated with frailty (odds ratio [OR] = 1.06; 95% confidence interval [CI]: 1.01–1.12), whereas hsCRP was independently associated with both prefrailty (OR = 1.03; 95% CI: 1.01–1.06) and frailty (OR = 1.07; 95% CI: 1.02–1.12). Furthermore, both markers were positively correlated with the number of Fried’s criteria that were met and were independently associated with the criteria of exhaustion (Hcy: OR = 1.03, 95% CI: 1.00–1.06), weakness (hsCRP: OR = 1.03, 95% CI: 1.01–1.05), and low physical activity (hsCRP: OR = 1.04, 95% CI: 1.02–1.06). Thus, our results highlight the importance of inflammation in age-related physical decline and, in particular, its association with fatigue, low strength, and decreased physical activity.

Sign in / Sign up

Export Citation Format

Share Document