scholarly journals Changes in white blood cell, red blood cell and platelet parameters following short term aerobic exercise in students of Nnamdi Azikiwe University, Nigeria

2020 ◽  
Vol 4 (2) ◽  
pp. 73-78
Author(s):  
Okeke Chizoba O ◽  
◽  
Mama Emmanuel I ◽  
Akosile Christopher O ◽  
Ani Kenneth U ◽  
...  
Keyword(s):  
Blood Cell ◽  
White Blood Cell ◽  
Red Blood Cell ◽  
Hematological Parameters ◽  
Significant Negative Correlation ◽  
Short Term ◽  
Distribution Width ◽  
Post Exercise ◽  
Post Test ◽  
Ethical Approval

Background: Haematological changes have been associated with physical activity (exercise) and these changes have been found to involve leucocytes, red blood cells and thrombocytes depending on variables such as the duration and intensity of the exercise. Objective: This experimental pre-post test study was designed to assess the changes in white blood cell, red blood cell and platelet parameters following short term exercise. Method: A total of 30 participants with an average age of 23.8 ± 1.98 years participated in the standard treadmill exercise (Bruce protocol) for 30 minutes on voluntary basis. Blood samples were collected from the subjects before exercise, immediately after exercise and 24 hours after exercise. Hematological parameters were analyzed using hematology auto-analyzer. Height, weight, body mass index and blood pressure of the participant were measured. Ethical approval was obtained from the Ethics committee of Faculty of Health Sciences and Technology and informed consent of the participants were obtained. Statistical Package for Social Sciences version 21 was used for statistical analysis. Results: The platelet count significantly increased post-exercise compared to pre-exercise and decreased 24hours post-exercise compared to postexercise value. Conversely, the Platelet distribution width (PDW) significantly decreased at post-exercise compared to pre-exercise, and significantly increased at 24hours post exercise compared to post-exercise value. Moreover, there was a significant increase in Mean platelet volume (MPV) at 24hours post-exercise compared to post exercise and a significant decrease in Plateletcrit (PCT) at 24hours post-exercise compared to post-exercise. At post-exercise and 24hours post-exercise, the total lymphocyte count was significantly higher in females while the granulocyte count was significantly higher in males. Also at 24 hours post exercise the MCHC was significantly higher in females compared to males. At post-exercise, there was a significant positive correlation between BMI and MCH (r=0.512, P=0.004) and BMI and MCHC (r=0.553, P=0.003) while there was a significant negative correlation between BMI and MPV (r=-0.367, P=0.046). Conclusion: Short term exercise causes significant alterations in platelet parameters than other hematological parameters.

scholarly journals Red blood cell profile in patients with mild, moderate and severe COVID-19

2021 ◽  
Vol 15 (2) ◽  
pp. 26-31
Author(s):  
Khushbhun Nahar Layla ◽  
Shahanara Yeasmin ◽  
Afrina Binte Azad ◽  
Masba Uddin Chowdhury ◽  
Nasrin Sultana ◽  
...  
Keyword(s):  
Blood Cell ◽  
Red Blood Cell ◽  
Hematological Parameters ◽  
Hemoglobin Concentration ◽  
Significant Negative Correlation ◽  
Mean Corpuscular Hemoglobin ◽  
Rt Pcr ◽  
Distribution Width ◽  
Significant Difference ◽  
Bonferroni Test

Background and objectives: Coronavirus disease 2019 (COVID-19) pandemic has affected millions of people world-wide. It is caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Increasing evidence has shown abnormalities of different hematological parameters with the severity of the diseases. The present study was undertaken to determine the red blood cell (RBC) profile in different categories of COVID-19 patients. Materials and methods: The study was conducted from January 2020 to December 2020. Reverse transcriptase-polymerase chain reaction (RT-PCR) positive COVID-19 patients were enrolled. Patients were categorized into mild, moderate and severe COVID-19 cases. Blood samples were analyzed by Automated Hematology Analyzer for hemoglobin concentration, total erythrocyte count and RBC indices. ANOVA followed by Bonferroni test, Chi square test, Spearman’s rho correlation coefficient test were performed as applicable using SPSS version 25.0. Results: A total of 100 RT-PCR positive COVID-19 patients were included in the study. There were 25, 38 and 37 mild, moderate and severe cases respectively. The mean age of the study participants was 44.68 + 13.16 years (range: 18 to 65 years). There were 67 (67%) males and 33 (33%) females. No significant difference in hemoglobin (Hb), hematocrit (HCT), total RBC count, red blood cell distribution width (CDW) was observed among the three groups. Significant negative correlation of mean corpuscular volume (MCV) and mean corpuscular hemoglobin (MCH); rs-0.362 & -0.255 respectively) was observed with disease severity. Conclusion: The study showed low MCV and MCH were significantly related with the severity of the COVID-19 illness. Therefore, comprehensive analysis of the RBC profile would be helpful to understand the disease course. Ibrahim Med. Coll. J. 2021; 15(2): 26-31

scholarly journals Reference intervals for hematology test parameters from apparently healthy individuals in southwest Ethiopia

2018 ◽  
Vol 6 ◽  
pp. 205031211880762 ◽  
Author(s):  
Lealem Gedefaw Bimerew ◽  
Tesfaye Demie ◽  
Kaleab Eskinder ◽  
Aklilu Getachew ◽  
Shiferaw Bekele ◽  
...  
Keyword(s):  
Platelet Count ◽  
Blood Cell ◽  
White Blood Cell ◽  
Red Blood Cell ◽  
Hematological Parameters ◽  
Age Groups ◽  
Reference Interval ◽  
Reference Intervals ◽  
Southwest Ethiopia ◽  
Apparently Healthy

Background: Clinical laboratory reference intervals are an important tool to identify abnormal laboratory test results. The generating of hematological parameters reference intervals for local population is very crucial to improve quality of health care, which otherwise may lead to unnecessary expenditure or denying care for the needy. There are no well-established reference intervals for hematological parameters in southwest Ethiopia. Objective: To generate hematological parameters reference intervals for apparently healthy individuals in southwest Ethiopia. Methods: A community-based cross-sectional study was conducted involving 883 individuals from March to May 2017. Four milliliter of blood sample was collected and transported to Jimma University Medical Center Laboratory for hematological analysis and screening tests. A hematological parameters were measured by Sysmex XS-500i hematology analyzer (Sysmex Corporation Kobe, Japan). The data were analyzed by SPSS version 20 statistical software. The non-parametric independent Kruskal–Wallis test and Wilcoxon rank-sum test (Mann–Whitney U test) were used to compare the parameters between age groups and genders. The 97.5 percentile and 2.5 percentile were the upper and lower reference limit for the population. Results: The reference interval of red blood cell, white blood cell, and platelet count in children were 4.99 × 1012/L (4.26–5.99 × 1012/L), 7.04 × 109/L (4.00–11.67 × 109/L), and 324.00 × 109/L (188.00–463.50 × 109/L), respectively. The reference interval of red blood cell, white blood cell, and platelet count in adults was 5.19 × 1012/L (4.08–6.33 × 1012/L), 6.35 × 109/L (3.28–11.22 × 109/L), and 282.00 × 109/L (172.50–415.25 × 109/L), respectively. The reference interval of red blood cell, white blood cell, and platelet count in geriatrics were 5.02 × 1012/L (4.21–5.87 × 1012/L), 6.21 × 109/L (3.33–10.03 × 109/L), and 265.50 × 109/L (165.53–418.80 × 109/L), respectively. Most of the hematological parameters showed significant differences across all age groups. Conclusion: Most of the hematological parameters in this study showed differences from similar studies done in the country. This study provided population-specific hematological reference interval for southwest Ethiopians. Reference intervals should also be established in the other regions of the country.

scholarly journals Red Blood Cell Variables in Children and Adolescents regarding the Age and Sex

2019 ◽  
Author(s):  
Jasmina PLUNCEVIC GLIGOROSKA ◽  
Serjoza GONTAREV ◽  
Beti DEJANOVA ◽  
Lidija TODOROVSKA ◽  
Daniela SHUKOVA STOJMANOVA ◽  
...  
Keyword(s):  
Blood Cell ◽  
Children And Adolescents ◽  
Red Blood Cell ◽  
Hematological Parameters ◽  
Hemoglobin Concentration ◽  
Female Group ◽  
Distribution Width ◽  
Hematological Indices ◽  
Significant Difference ◽  
Age And Sex

Background: This study aimed to assess the basic red blood cell variables and hematological indices in children and adolescents and analyze the differences regarding age and sex. Methods: Overall, 320 young participants, age 8 to 18 yr, were enrolled at Laboratory of Sport’s Medicine, Medical Faculty, Skopje, Macedonia in 2016. Capillary blood samples were drawn and following hematologic parameters were measured: the red blood cell count (RBC), hemoglobin concentration (Hb), hematocrit level (Hct) and hematological indexes: mean corpuscular volume (MCV), mean hemoglobin concentration (MCH), mean corpuscular hemoglobin concentration (MCHC) and red cell distribution width (RDW). Results: RBC variables in male group showed high statistical level of significance between age different groups (P=0.001) for all studied parameters except MCHC (P=0.423) and RDW (P=0.174). ANOVA test and multivariate tests in female group showed that there was no significant difference for all hematological parameters between age different groups. Regarding the sex differences, male participants had significantly higher red blood count (P<0.001), hemoglobin content (P<0.001) and hematocrit (P<0.001). Conclusion: Hematological parameters in adolescent as inhomogeneous population are not quantified sufficiently, especially hematological indices. RBC variables, regardless of the age, differ very much between male and female examinees, in favor of the male examinees. Hematological indices were insignificantly higher in males. Regarding the age of examinees, RBC variables showed significant inter-groups differences only within male adolescents. While with girls, ages span 8 to 18 yr, we did not find significant differences for most of the hematological variables.

scholarly journals Hematological and histo-architectural damages in the kidney and liver of Nile tilapia on exposure to kinalux

2015 ◽  
Vol 26 (2) ◽  
pp. 173-178 ◽  
Author(s):  
MTA Nannu ◽  
GM Mostakim ◽  
MH Khatun ◽  
MK Rahman ◽  
MI Sadiqul
Keyword(s):  
Blood Cell ◽  
White Blood Cell ◽  
Red Blood Cell ◽  
Oreochromis Niloticus ◽  
Nile Tilapia ◽  
Hematological Parameters ◽  
Lethal Concentration ◽  
Median Lethal Concentration ◽  
Nile Tilapia Oreochromis Niloticus ◽  
Parallel Control

Study was conducted to assess the histo-architectural damages of kidney and liver and hematological parameters in Nile tilapia (Oreochromis niloticus) after sub-lethal exposure to kinalux. Fish was exposed to two sub-lethal concentrations (10% and 50%, 0.052 and 0.259ppm of median lethal concentration, respectively) of kinalux for 90 days and a parallel control was run simultaneously. Kidney and liver of exposed individuals exhibited some remarkable changes in their histology in comparison to control. Significant changes also occurred in the number of red blood cell (RBC) and white blood cell (WBC). Duration of exposure appears to have a profound effect on kidney and liver as with increasing duration of exposure histo-architectural damages become more severe.Progressive Agriculture 26 (2): 173-178, 2015

High red blood cell distribution width is associated with a risk of short-term mortality in hospitalized surgical, but not clinical patients

2020 ◽  
Vol 39 ◽  
pp. 150-156
Author(s):  
Nayara Cristina da Silva ◽  
Isaías Valente Prestes ◽  
Wander Antônio Gontijo ◽  
Geórgia das Graças Pena
Keyword(s):  
Blood Cell ◽  
Red Blood Cell ◽  
Cell Distribution ◽  
Short Term ◽  
Distribution Width ◽  
Short Term Mortality ◽  
Red Blood Cell Distribution

scholarly journals Application of innovative hemocytometric parameters and algorithms for improvement of microcytic anemia discrimination

2015 ◽  
Vol 7 (2) ◽  
Author(s):  
Margreet Schoorl ◽  
Marianne Schoorl ◽  
Johannes Van Pelt ◽  
Piet C.M. Bartels
Keyword(s):  
Iron Deficiency ◽  
Blood Cell ◽  
Iron Deficiency Anemia ◽  
Red Blood Cell ◽  
Hematological Parameters ◽  
Deficiency Anemia ◽  
Zinc Protoporphyrin ◽  
Distribution Width ◽  
New Algorithms ◽  
Rbc Count

Hemocytometric parameters like red blood cell (RBC) count, mean red blood cell volume (MCV), reticulocyte count, red blood cell distribution width (RDW-SD) and zinc protoporphyrin (ZPP) are frequently established for discrimination between iron-deficiency anemia and thalassemia in subjects with microcytic erythropoiesis. However, no single marker or combination of tests is optimal for discrimination between iron-deficiency anemia and thalassemia. This is the reason why many algorithms have been introduced. However, application of conventional algorithms, only resulted in appropriate classification of 30-40% of subjects. In this mini-review the efficacy of innovative hematological parameters for detection of alterations in RBCs has been considered. It refers to parameters concerning hemoglobinization of RBCs and reticulocytes and the percentages microcytic and hypochromic RBCs, for discrimination between subjects with iron-deficiency anemia (IDA) or thalassemia as well as a combination of both. A new discriminating tool including the above mentioned parameters was developed, based on two precondition steps and discriminating algorithms. The percentage microcytic RBCs is considered in the first pre-condition step. MCV, RDW-SD and RBC count are applied in the second precondition step. Subsequently, new algorithms, including conventional as well as innovative hematological parameters, were assessed for subgroups with microcytic erythropoiesis. The new algorithms for IDA discrimination yielded results for sensitivity of 79%, specificity of 97%, positive and negative predictive values of 74% and 98% respectively. The algorithms for beta-thalassemia discrimination revealed similar results (74%, 98%, 75% and 99% respectively). We advocate that innovative algorithms, including parameters reflecting hemoglobinization of RBCs and reticulocytes, are integrated in an easily accessible software program linked to the hematology equipment to improve the discrimination between IDA and thalassemia.

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