scholarly journals Study of Optic Nerve Sheath Diameter in Normal Nepalese Adults Using Ultrasound

2018 ◽  
Vol 3 (1) ◽  
pp. 357-360 ◽  
Author(s):  
Bidur KC ◽  
Amit Thapa
Keyword(s):  
Optic Nerve ◽  
Optic Nerve Sheath Diameter ◽  
Cross Sectional Study ◽  
Optic Nerve Sheath ◽  
P Value ◽  
Cross Sectional ◽  
Non Invasive ◽  
Normal Limits ◽  
Nerve Sheath ◽  
Significant Difference

Introduction: Though invasive intracranial devices are gold standard to calculate intracranial pressure (ICP); these are not without any complications. Non-invasive measurement of ICP by Ultrasonography could be a safe and portable technique.Objectives: The objective of the study was to measure and compare values of optic nerve sheath diameter of both eyes in healthy Nepalese adults.Methodology: A prospective cross-sectional study of healthy adult Nepalese volunteers was performed using a 7.5 MHz linear Ultrasound probe on the closed eyelids; optic nerve sheath diameter (ONSD) was measured 3 mm behind the globe in each eye.Results: Optic nerve sheath diameter (ONSD) of both eyes was measured in 100 healthy volunteers of age ranged from 15 to 75 years with a mean of 30.21 ± 14.05 years. There were 18 (18%) male and 82 (82%) female. ONSD for right eye ranged from 3.20 to 4.90 mm with mean of 4.10 ± 0.50 mm and left eye from 3.20 to 4.80 mm with mean of 4.22 ± 0.49 mm. P value for right and left eye ONSD (P = 0.06) and male and female (P = 0.12 and 0.85 for right and left ONSD respectively) were within normal limits. ONSD has no correlation with age (P = 0.27 and 0.27 for right and left ONSD respectively).Conclusion Mean of optic nerve sheath diameter (ONSD) is 4.10mm and 4.22 mm for right and left eye respectively. There is no statistical significant difference in mean of ONSD between right and left eye. BJHS 2018;3(1)5 : 357-360

scholarly journals PERBEDAAN OPTIC NERVE SHEATH DIAMETER (ONSD) PADA RESPONDEN NORMAL DAN NYERI KEPALA

Biomedika ◽  
2019 ◽  
Vol 11 (2) ◽  
pp. 96-104
Author(s):  
Sulistyani Sulistyani ◽  
Rivan Danuaji
Keyword(s):  
Optic Nerve ◽  
Normal Volunteer ◽  
Optic Nerve Sheath Diameter ◽  
Optic Nerve Sheath ◽  
Cross Sectional ◽  
Average Value ◽  
Normal People ◽  
Nerve Sheath ◽  
Significant Difference ◽  
Transorbital Sonography

Nyeri kepala merupakan penanda adanya gangguan intrakranial. Nervus optikus merupakan saraf kranialis yang mudah dipengaruhi langsung adanya gangguan intrakranial. Kalimatnya Jumping. Kelainan nervus optikus dapat diketahui dengan adanya pelebaran optic nerve sheath diameter (ONSD). ONSD dapat diukur dengan transorbital sonografi yang bersifat nonimvasif. Penelitian ini bertujuan membedakan diameter ONSD pada orang yang nyeri kepala dan orang normal. Penelitian ini menggunakan pendekatan observasional analitik dengan metode cross sectional. Responden diambil dari pasien rawat inap dan responden normal. Hasil penelitian didapatkan rata – rata nilai ONSD pada pasien nyeri kepala adalah 0,52 ± 0,86 dan pada responden normal adalah 0,40 ± 0,57 (p < 0,05). Terdapat perbedaan signifikan nilai ONSD pada pasien normal dan nyeri kepala. Penelitian ini membuktikan bahwa terdapat gangguan intrakranial pada orang dengan nyeri kepala dan dapat digunakan sebagai deteksi dini.Kata Kunci: Optic Nerve Sheath Diameter (ONSD), Responden Normal, Nyeri KepalaHeadache is a sign of intracranial disorders. The optic nerve is a cranial nerve that is easily affected directly by intracranial disorders. The sentence is Jumping. Optic nerve abnormalities can be identified by the widening of the optic nerve sheath diameter (ONSD). ONSD can be measured by transorbital sonography which is nonimvasive. This study aims to distinguish the ONSD diameter in people with headaches and normal people. This research uses an analytic observational approach with cross sectional method. Respondents were taken from inpatients and normal respondents. The results showed that the average value of ONSD in headache patients was 0.52 ± 0.86 and in normal respondents was 0.40 ± 0.57 (p <0.05). There is a significant difference in the value of ONSD in normal patients and headaches. This research proves that there are intracranial disorders in people with headaches and can be used as early detection.Keyword: Optic nerve sheath diameter , headache , normal volunteer 

scholarly journals Effects of sevoflurane and propofol on the optic nerve sheath diameter in patients undergoing laparoscopic gynecological surgery: A Randomized controlled clinical studies

2021 ◽  
Author(s):  
Weilian Geng ◽  
Changxing Chen ◽  
Xingfeng Sun ◽  
Shaoqiang Huang
Keyword(s):  
Optic Nerve ◽  
Optic Nerve Sheath Diameter ◽  
Optic Nerve Sheath ◽  
Controlled Study ◽  
Anesthesia Induction ◽  
Gynecological Surgery ◽  
Time Points ◽  
Randomized Controlled ◽  
Nerve Sheath ◽  
Significant Difference

Abstract Background The results of studies on changes in intracranial pressure in patients undergoing laparoscopic surgery are inconsistent. Meanwhile, previous neurosurgery studies have suggested that propofol and sevoflurane have inconsistent effects on cerebral blood flow and cerebrovascular self-regulation. The purpose of this study is to compare changes in the optic nerve sheath diameter in patients undergoing laparoscopic gynecological surgery under anesthetic maintenance with propofol versus sevoflurane. Methods This study included 110 patients undergoing laparoscopic gynecological surgery with an estimated operative time of more than 2 hours under general anesthesia. The study was a randomized controlled study. The optic nerve sheath diameter（ONSD）at various time points was measured by ultrasound, including when the patients entered the operating room (Tawake), after successful anesthesia induction and endotracheal intubation (Tinduction), when the body position was adjusted to the Trendelenburg position and the CO2 pneumoperitoneum pressure reached 14 mmHg, which was recorded as T0. Then, measurements were conducted every 15 minutes for the first 1 hour and then once every hour until the end of the surgery（T15,T30,T45 ,T1h ,T2h…）, after the end of surgery and the tracheal tube was removed (Tend), and before the patients were transferred to the ward (Tpacu).Results A significant difference in optic nerve sheath diameter was found between two groups at T15, T30, T45 (4.64±0.48mm and 4.50±0.29mm, respectively, p=0.031;4.77±0.45mm and 4.62±0.28mm, respectively, p=0.036;4.84±0.46mm and 4.65±0.30mm, respectively, p=0.012), while there was no significant difference at Tawake and other time points. Conclusion During laparoscopic gynecological surgery lasting more than 2 hours, the optic nerve sheath diameter was slightly larger in the propofol group than that in the sevoflurane group in the first 45 minutes. No significant difference was observed between the two groups 1 hour after surgery. Trial registration clinicaltrials.gov，NCT03498235. Retrospectively registered 1 March2018,https://register.clinicaltrials.gov/prs/app/action/SelectProtocol?sid=S0007UMM&selectaction=Edit&uid=U00040C5&ts=39&cx=c7i8icThe manuscript adheres to CONSORT guidelines.

Ultrasound Nomograms of the Fetal Optic Nerve Sheath Diameter

2018 ◽  
Vol 40 (04) ◽  
pp. 476-480 ◽  
Author(s):  
Karina Krajden Haratz ◽  
Yaakov Melcer ◽  
Zvi Leibovitz ◽  
Hagit Feit ◽  
Tally Lerman-Sagie ◽  
...  
Keyword(s):  
Optic Nerve ◽  
Optic Nerve Sheath Diameter ◽  
Quadratic Equation ◽  
Optic Nerve Sheath ◽  
Specific Reference ◽  
Intraobserver Variability ◽  
Cross Sectional ◽  
Mean Values ◽  
Nerve Sheath ◽  
The Mean

Abstract Objective To construct prenatal age-specific reference intervals for sonographic measurements of the optic nerve sheath diameter (ONSD) during gestation in normal fetuses. Materials and Methods Prospective cross-sectional study of fetuses assessed in antenatal ultrasound units between 2010 and 2014. The examination was based on a technique for the sonographic assessment of ONSD previously published by our group. The mean values and SDs of the ONSD were modeled as a function of the gestational week by curve estimation analysis based on the highest adjusted R2 coefficient. Repeatability tests were performed to assess intraobserver variability and interobserver agreement. Results During the study period 364 healthy fetuses were enrolled. The mean values for the ONSD varied from 0.6 mm at 15–16 weeks to 2.8 mm at 37–38 weeks. The ONSD grows in a linear fashion throughout gestation, with a quadratic equation providing an optimal fit to the data (adjusted R2 = 0.957). Conclusion Sonographic age-specific references for the fetal ONSD are presented. This data may assist in the decision-making process in fetuses with a suspected increase in intracranial pressure, or anomalies affecting the development of optic stalks, such as optic hypoplasia and septo-optic dysplasia.

scholarly journals The relationship between computed tomography measurement of the optic nerve sheath diameter and elevated intracranial pressure in non-trauma patients

2016 ◽  
Vol 20 (1) ◽  
Author(s):  
Daniël Luyt ◽  
Delmé Hurter ◽  
Gina Joubert
Keyword(s):  
Computed Tomography ◽  
Optic Nerve ◽  
Intracranial Pressure ◽  
Digital Images ◽  
Optic Nerve Sheath Diameter ◽  
Optic Nerve Sheath ◽  
Trauma Patients ◽  
Cross Sectional ◽  
Nerve Sheath ◽  
The Brain

Background: The early detection and treatment of raised intracranial pressure (ICP) is critical in the prevention of mortality and morbidity as a result of secondary ischemic brain injury. Measuring the optic nerve sheath diameter (ONSD) on computed tomography (CT) to predict raised ICP may be useful in cases where routine CT investigations of the brain are indicated and invasive ICP monitoring is not available, or a lumbar puncture (LP) is contraindicated.Objective: The purpose of this study was to determine if the ONSD can be measured on digital images obtained by routine CT investigations of the brain, to identify patients with non-traumatic causes of elevated ICP, and to provide the observer with a non-invasive, objective measurement to predict elevated ICP.Method: We conducted a cross-sectional, retrospective analysis of anonymised patient data, comparing the ONSD on CT imaging with the opening pressure manometry during LP on patients who presented with focal neurology or with a Glasgow coma scale score of less than 15. The study sample consisted of 67 patients, ≥18 years of age, treated at the emergency department of the Kimberly Hospital Complex from 01 March 2013 to 31 December 2014.Results: An ONSD measurement of ≥4.8 mm identified patients with an elevated ICP with a sensitivity of 92.9% and a specificity of 97.6%, using a 95% confidence interval. Raising the ONSD cut-off value to ≥5.0 mm decreased the sensitivity to 85.7% but increased the specificity to 100%, eliminating all patients with a normal ICP.Conclusion: The ONSD can be measured on digital images obtained by routine CT investigations of the brain to predict elevated ICP in non-trauma patients, ≥18 years of age, with acceptable sensitivity and specificity.

scholarly journals How accurate is ultrasound of the optic nerve sheath diameter performed by inexperienced operators to exclude raised intracranial pressure?

2015 ◽  
Vol 19 (1) ◽  
Author(s):  
G. J. Du Toit ◽  
D. Hurter ◽  
M. Nel
Keyword(s):  
Optic Nerve ◽  
Intracranial Pressure ◽  
Lumbar Puncture ◽  
Predictive Value ◽  
Optic Nerve Sheath Diameter ◽  
Optic Nerve Sheath ◽  
Ultrasound Measurement ◽  
Raised Intracranial Pressure ◽  
Cross Sectional ◽  
Nerve Sheath

Background: It has been well documented that ultrasound measurement of the optic nerve sheath diameter performed by an experienced operator shows good correlation with raised intracranial pressure, irrespective of the cause. Objective: To establish the accuracy of this technique performed by inexperienced operators.Method: A prospective analytical cross-sectional study was conducted. All patients ≥18 years of age who presented at our medical casualty and emergency departments with suspected meningitis were enrolled in the study. All patients were evaluated with the use of optic nerve sheath diameter ultrasound with or without computed tomography brain scan prior to lumbar puncture. Lumbar puncture opening pressure measurements were compared with the ultrasound measurements.Results: A total of 73 patients were enrolled in the study, of whom 14 had raised intracranial pressure. The study had a sensitivity of 50% (95% confidence interval (CI) 26.8%–73.2%) and specificity of 89.8% (95% CI 79.5%–95.3%) with a positive predictive value of 54.8% (95% CI 29.1%–76.8%) and negative predictive value of 88.3% (95% CI 77.8%–94.2%). The likelihood ratio of a positive test was 4.92 (95% CI 1.95–11.89) and that of a negative test 0.56 (95% CI 0.29–0.83). Cohen’s kappa value was 0.41 which indicates a moderate agreement. The receiver operating characteristic (ROC) curve had an area under the curve (AUC) of 0.73 (95% CI 0.51–0.95). Conclusion: Ultrasound measurement of the optic nerve sheath diameter can be used to exclude raised intracranial pressure, even in the hands of inexperienced operators.

scholarly journals Optic Nerve Sheath Diameter Assessment Used As a Non-Invasive Tool To Dynamically Monitor Intracranial Pressure

2021 ◽  
Author(s):  
Guo-Biao Wu ◽  
Jun Tian ◽  
Xiao-Bing Liu ◽  
Zhi-Yong Wang ◽  
Jian-Ying Guo
Keyword(s):  
Optic Nerve ◽  
Intracranial Pressure ◽  
Supine Position ◽  
Dynamic Test ◽  
Optic Nerve Sheath Diameter ◽  
Optic Nerve Sheath ◽  
Strongly Correlated ◽  
Non Invasive ◽  
Nerve Sheath ◽  
Good Agreement

Abstract Objective: This study aimed to detect whether optic nerve sheath diameter (ONSD) can be used to dynamically monitor intracranial pressure (ICP). Methods: Adult patients being monitored for invasive ICP on day one after hospital admission were included. For each patient, ONSD was first measured in the supine position, then at the 30° head-up position. The dynamic test was conducted in 16 patients. The ONSD was measured in the supine position once a day for three continuous days (day one to day three after admission).Results: The ONSD and ICP values obtained in the supine position on admission were strongly correlated (r of 0.799). When patients changed their position from supine to the 30° head-up position, the ICP and ONSD values decreased correspondingly. However, the change in ICP did not correlate well with the change in ONSD (r of 0.358). In the dynamic test, a good agreement between ICP and ONSD only existed in three (18.75%) patients. In addition, three patients had completely different profiles for ICP and ONSD.Conclusions: The results suggest that the changes in ONSD and ICP values were not correlated well after dynamic observation. Measurement of ONSD may not be a suitable tool to dynamically monitor ICP.

scholarly journals Normal Values of Optic Nerve Sheath Diameter on Computed Tomography and effect of Raised Intracranial Pressure on Head Injury Patients in North Central Nigeria

2021 ◽  
pp. 10-18
Author(s):  
Ukamaka Dorothy Itanyi ◽  
Adebukola Morenike Leslie ◽  
James Nwabueze Chukwuegbo
Keyword(s):  
Optic Nerve ◽  
Head Injury ◽  
Intracranial Pressure ◽  
Optic Nerve Sheath Diameter ◽  
Optic Nerve Sheath ◽  
Radiology Department ◽  
P Value ◽  
Raised Intracranial Pressure ◽  
North Central ◽  
Nerve Sheath

Aim: To establish a local nomogram of Computed Tomographic measurement of Optic Nerve Sheath Diameter and determine the values that can objectively predict raised intracranial pressure. Study design:  observational retrospective study Place and duration of study:  Department of Radiology of University of Abuja teaching hospital, Abuja from March 2016 to February 2020. Methodology: We included  images of 356 patients referred to the Radiology department for brain CT. Data was grouped into three:(A) 200 non head injury patients as control,(B) head injury patients without radioclinical signs of raised ICP ,(C) head injury patients with at least one radiologic sign of  raised ICP.ONSD  obtained in axial scans at 3mm retrobulbar region at constant  window width and level of 250/50 were analysed using SAS software version 9.3 and statistical level of significance set at 0.05. Result: Mean ONSD of 200 normal patients was 4.4mm± 0.5 with no significant correlation with age and side. Mean ONSD of 118 head injury patients with CT signs of raised ICP was 6.0mm±0.7 while mean ONSD of 38 head injury patients without CT signs of raised ICP was 4.3mm±0.7. ONSD was slightly higher in patients with significant midline shift compared with patients without shift but no correlation with degree of shift. The ONSD value above which raised ICP can be predicted with the highest sensitivity and specificity was >5.2mm with Receiver Operating Characteristic curve (ROC) demonstrating an area under the curve of 0.9796 (p-value < 0.0001) with specificity of 93.5% and sensitivity of 90.7%. Conclusion: There is a positive correlation between ONSD measurement on CT and intracranial pressure. This measurement is therefore recommended as an additional indirect radiological marker of raised ICP. Normal mean ONSD in a North-Central Nigerian population is 4.4mm± 0.5 with 5.2mm proposed as the upper limit of normal.

Sign in / Sign up

Export Citation Format

Share Document