scholarly journals Pseudopelade of Brocq: a clinico-therapeutic challenge!

2014 ◽  
Vol 11 (3) ◽  
pp. 273-275
Author(s):  
S Jain
Keyword(s):  
Lupus Erythematosus ◽  
Scalp Hair ◽  
Young Male ◽  
Clinical Syndrome ◽  
Definitive Diagnosis ◽  
Discoid Lupus Erythematosus ◽  
Pathological Features ◽  
Therapeutic Challenge ◽  
Lichen Planopilaris ◽  
Specific Disease

Pseudopelade of Brocq is a clinical syndrome comprising of scarring alopecia and fibrosis in which distinct pathological features are absent. It is not a specific disease, rather a pattern of cicatricial alopecia. However, if a definitive diagnosis of DLE (discoid lupus erythematosus), LPP (Lichen planopilaris) or any other condition can be made on the basis of clinical, histopathological or immunofluorescent features, then this term cannot be used. Here we report the case of a 20 year old young male who presented to us with complaints of loss of scalp hair for 2 years which were associated with mild itching. The condition is as such rare in prevalence and hence we report the same in view of its unique presentation. DOI: http://dx.doi.org/10.3126/hren.v11i3.9652 Health Renaissance 2013;11(3):273-275

scholarly journals Focal alopecia in parietal area in adult women — assessment of usefulness of trichoscopy in making a proper diagnosis

2020 ◽  
Vol 3 (2) ◽  
pp. 86-96
Author(s):  
Dominik Mikiel ◽  
Adriana Polańska ◽  
Aleksandra Dańczak‑Pazdrowska ◽  
Ryszard Żaba ◽  
Zygmunt Adamski
Keyword(s):  
Hair Loss ◽  
Lupus Erythematosus ◽  
Diagnostic Method ◽  
Skin Surface ◽  
Control Group ◽  
Discoid Lupus Erythematosus ◽  
Adult Women ◽  
Lichen Planopilaris ◽  
Non Invasive ◽  
Parietal Area

Introduction. Focal alopecia in the parietal area is one of the types of hair loss that can be found in dermatological practice. Trichoscopy is a non-invasive and easily accessible diagnostic method widely used in scalp disorders.Aim. The aim of this study was to assess the usefulness of trichoscopy in the non-invasive diagnosis of focal hair loss in adult women.Material and Methods. The study included 40 adult women. The study group consisted of 30 patients including 10 patients with alopecia areata (AA), 10 patients with discoid lupus erythematosus (DLE) and 10 with classical form of lichen planopilaris (LPP). The control group consisted of 10 healthy volunteers. Four groups of structures observed in trichoscopic examination were evaluated: hair follicle openings, hair shafts, vessels, perifollicular and interfollicular skin surface. Results. Among patients with AA the most frequently observed trichoscopic structures were: yellow dots in 100% (10/10), broken hairs in 90% (9/10), hairs resembling exclamation marks in 90% (9/10). DLE patients most often presented white / white-pink structureless areas and prominent, interfollicular scaling in 100% (10/10) and 90% (9/10) of cases, respectively. On the other hand, in the group of patients with LPP, the most frequent findings were: fine perifollicular scaling in 100% (10/10) and linear, slightly branched vessels arranged concentrically around the follicular openings - both features observed also in 100% (10/10) of cases.Conclusion. Trichoscopy as a non-invasive diagnostic method may be helpful in differentiating non-scarring and scarring alopecia in the parietal area in women. Moreover, there are some trichoscopic features typical for AA, DLE and LPP, which allow for differentiation and facilitate the diagnosis of these entities.

scholarly journals Trichoscopy in common scalp alopecia: an observational study

2020 ◽  
Vol 6 (3) ◽  
pp. 361
Author(s):  
Krishnendra Varma ◽  
Ujjwal Singh ◽  
Manu Kataria
Keyword(s):  
Observational Study ◽  
Lupus Erythematosus ◽  
Seborrheic Dermatitis ◽  
Daily Practice ◽  
Common Finding ◽  
Discoid Lupus Erythematosus ◽  
Diagnostic Dilemma ◽  
Lichen Planopilaris ◽  
Medical College ◽  
One Year

<p class="abstract"><strong>Background:</strong> Many patients of alopecia are encountered in daily practice with diagnostic dilemma. Trichoscopy is a sensitive, non-invasive tool which aids in clinical diagnosis.</p><p class="abstract"><strong>Methods:</strong> An observational study performed in adult patients with alopecia attending R.D. Gardi Medical College, Ujjain, over a period of one year. Trichoscopy was performed using a Dinolite digital microscope with both polarized and non polarized modes.<strong></strong></p><p class="abstract"><strong>Results:</strong> 269 patients of alopecia (257 non cicatricial, 12 cicatricial) aged 18-50 years were enrolled. The diagnosis was made after detailed history and clinical examination. 173 (64.3%) males and 96 (35.7%) females. 45.4% patients were diagnosed to have alopecia areata in which yellow dots were the most common trichoscopic finding observed in 88.5% patients. 37.2% patients were diagnosed with androgenetic alopecia with hair diameter diversity &gt;20% observed in all the patients. 9.3% patients were diagnosed to have telogen effluvium with short vellus hair seen in 64% patients. 3.7% of the patients were diagnosed to have seborrheic dermatitis with arborizing vessels being the most common finding seen in 90% patients. 2.9% patients were diagnosed with lichen planopilaris in which loss of follicles and peritubular white casts were seen in all the cases. 0.9% patients were diagnosed to have discoid lupus erythematosus with hyperkeratotic follicular plugging seen in all the cases. Overall yellow dots were the most common trichoscopic findings seen in 61% cases.</p><p class="abstract"><strong>Conclusions:</strong> Trichoscopy is a reliable diagnostic tool in hair and scalp disorders. Hence trichoscopic evaluation should be done in every case of alopecia.  </p><p class="abstract"> </p>

scholarly journals Eyelid discoid lupus erythematosus

2021 ◽  
Vol 12 (e) ◽  
pp. e28-e28
Author(s):  
Mehdi Khallaayoune ◽  
Siham Belmourida ◽  
Fatima Azzahra Elgaitibi ◽  
Mariame Meziane
Keyword(s):  
Lupus Erythematosus ◽  
Early Recognition ◽  
Delayed Diagnosis ◽  
Young Male ◽  
Lower Eyelid ◽  
Direct Immunofluorescence ◽  
Discoid Lupus Erythematosus ◽  
Erythematous Plaque ◽  
Lower Lip ◽  
Systemic Involvement

Discoid lupus erythematosus (DLE) most commonly affects the face and scalp. Palpebral involvement is rare and not evocative when presenting as the prime manifestation of the disease. We report hereby the case of a young male patient with isolated palpebral and labial DLE. A 34-year-old patient with no medical history was referred from ophthalmology for an erythematous plaque of the eyelid resisting usual treatment of blepharitis. Skin examination revealed a congestive erythema on the right lower eyelid with eyelash fall (Fig. 1). There was also an atrophic cheilitis of the lower lip with slight erosions (Fig. 2). Scalp, oral mucosa and the rest of the integument were not affected. Skin biopsy of the eyelid revealed marked orthokeratosis with slight basal vacuolization and perivascular lymphoplasma cells infiltrate. Direct immunofluorescence displayed a positive lupus band (Fig. 3). Work-up for systemic involvement was negative. Ophthalmologic assessment found no intraocular involvement. Hydroxychloroquine 200mg twice a day with clothing and chemical photoprotection were implemented allowing significant improvement after 3 months (Fig. 4). Palpebral involvement of DLE is uncommon compared to the other suggestive locations including scalp, nose, cheekbones, ears, neckline and hands. An isolated involvement does not suggest DLE at first sight and often leads to delayed diagnosis while scarring and lid deformities might be expected if left untreated [1]. Most commonly it presents as erythematous telangiectasic scaly plaques on the external third of lower eyelid. Blepharitis-like, madarosis, periorbital edema or cellulitis presentations have also been reported [2]. Differential diagnosis may arise with several chronic palpebral dermatoses, as carcinomas, eczema, blepharoconjunctivitis, or seborheic dermatosis. Assessment for intraocular involvement such as keratitis should always be performed [3]. Early recognition and treatment are essential to avoid eyelid complications as ectropion, entropion, and trichiasis. Photoprotection and antimalarials are the mainstay treatment showing remarkable efficacy.

scholarly journals Lichen planopilaris versus discoid lupus erythematosus: A trichoscopic perspective

2013 ◽  
Vol 5 (4) ◽  
pp. 204 ◽  
Author(s):  
BalachandraS Ankad ◽  
SavithaL Beergouder ◽  
VishnuM Moodalgiri
Keyword(s):  
Lupus Erythematosus ◽  
Discoid Lupus Erythematosus ◽  
Lichen Planopilaris

scholarly journals Value of CD123 immunohistochemistry and elastic staining in differentiating discoid lupus erythematosus from lichen planopilaris

2020 ◽  
Vol 12 (2) ◽  
pp. 62
Author(s):  
Mojgan Akbarzadeh-Jahromi ◽  
FatemehSari Aslani ◽  
Mozhdeh Sepaskhah ◽  
Zahra Bagheri
Keyword(s):  
Lupus Erythematosus ◽  
Discoid Lupus Erythematosus ◽  
Lichen Planopilaris

scholarly journals Diagnostic Accuracy of Trichoscopy in Inflammatory Scalp Diseases: A Systematic Review

Dermatology ◽  
2021 ◽  
pp. 1-10
Author(s):  
Joanna Golińska ◽  
Marta Sar-Pomian ◽  
Lidia Rudnicka
Keyword(s):  
Systematic Review ◽  
Contact Dermatitis ◽  
Lupus Erythematosus ◽  
Seborrheic Dermatitis ◽  
Pemphigus Vulgaris ◽  
Discoid Lupus Erythematosus ◽  
Pemphigus Foliaceus ◽  
Lichen Planopilaris ◽  
Systemic Analysis ◽  
Scalp Diseases

<b><i>Background:</i></b> The common inflammatory scalp diseases, such as psoriasis, seborrheic dermatitis, lichen planopilaris, discoid lupus erythematosus, contact dermatitis, or pemphigus may share similar clinical features. <b><i>Objective:</i></b> To identify and systematically review the available evidence on the accuracy of trichoscopy in inflammatory scalp disorders. <b><i>Methods:</i></b> A systematic review was performed according to Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. A total of 58 articles were included in the analysis. <b><i>Results:</i></b> The following trichoscopy features were found to show the highest specificity for the respective diseases: in psoriasis: diffuse scaling, simple and twisted red loops, red dots and globules, and glomerular vessels; in seborrheic dermatitis: atypical vessels, thin arborizing vessels, and structureless red areas; in discoid lupus erythematosus: follicular plugs and erythema encircling follicles; in lichen planopilaris: milky red areas or fibrotic patches; in contact dermatitis: twisted red loops; in pemphigus foliaceus: white polygonal structures and serpentine vessels; in pemphigus vulgaris: red dots with whitish halo and lace-like vessels; and in dermatomyositis: lake-like vascular structures. <b><i>Limitations:</i></b> Different nomenclature and variability in parameters, which were analyzed in different studies. <b><i>Conclusion:</i></b> This systemic analysis indicates that trichoscopy may be used with high accuracy in the differential diagnosis of inflammatory scalp diseases.

scholarly journals Primary Cicatricial Alopecia among Lybian patients: A Clinicopathological and Epidemiological study

2020 ◽  
Vol 2 (4) ◽  
pp. 275-278
Author(s):  
Fauzia Musbah ◽  
Keyword(s):  
Early Diagnosis ◽  
Lupus Erythematosus ◽  
Clinicopathological Characteristics ◽  
Study Data ◽  
Descriptive Statistics ◽  
Discoid Lupus Erythematosus ◽  
Lichen Planopilaris ◽  
Chi Squared ◽  
Folliculitis Decalvans ◽  
The Relationship

Introduction: Cicatricial alopecias are a group of disorders characterized by hair follicle destruction with the consequence of permanent hair loss. The current study was conducted to evaluate the epidemiological and clinicopathological characteristics of cicatricial alopecia in Libyan community. Methods: Thirty-one patients with confirmed diagnosis of cicatricial alopecia by biopsy and tricoscopy during Jan 2018 to Dec 2019 were included in this study. Data were collected by filling a pre-designed questionnaire by all included patients. Descriptive statistics were used for analyzing the results. Chi-squared test was performed to test the relationship between different variables using SPSS 22. Results: Out of 31 cases, 16.1% of patients suffered from lichen planopilaris (LPP), 25.8% discoid lupus erythematosus (DLE), 6% Folliculitis decalvans, 6.45% pseudopelade of brocq, and 16.12% Frontal fibrosing alopecia. Conclusions: Cicatricial alopecia was found to affect mainly middle-aged individuals, particularly females. Early diagnosis and treatment can decrease the burden of this concern.

scholarly journals Pili Torti: A Feature of Numerous Congenital and Acquired Conditions

2021 ◽  
Vol 10 (17) ◽  
pp. 3901
Author(s):  
Aleksandra Hoffmann ◽  
Anna Waśkiel-Burnat ◽  
Jakub Żółkiewicz ◽  
Leszek Blicharz ◽  
Adriana Rakowska ◽  
...  
Keyword(s):  
Lupus Erythematosus ◽  
Cleft Lip ◽  
Genetic Diseases ◽  
Growth Factor Receptor ◽  
Rare Condition ◽  
Hair Shaft ◽  
Discoid Lupus Erythematosus ◽  
Lichen Planopilaris ◽  
Netherton Syndrome ◽  
Pili Torti

Pili torti is a rare condition characterized by the presence of the hair shaft, which is flattened at irregular intervals and twisted 180° along its long axis. It is a form of hair shaft disorder with increased fragility. The condition is classified into inherited and acquired. Inherited forms may be either isolated or associated with numerous genetic diseases or syndromes (e.g., Menkes disease, Björnstad syndrome, Netherton syndrome, and Bazex–Dupré–Christol syndrome). Moreover, pili torti may be a feature of various ectodermal dysplasias (such as Rapp–Hodgkin syndrome and Ankyloblepharon-ectodermal defects-cleft lip/palate syndrome). Acquired pili torti was described in numerous forms of alopecia (e.g., lichen planopilaris, discoid lupus erythematosus, dissecting cellulitis, folliculitis decalvans, alopecia areata) as well as neoplastic and systemic diseases (such as cutaneous T-cell lymphoma, scalp metastasis of breast cancer, anorexia nervosa, malnutrition, cataracts, and chronic graft-vs-host disease). The condition may also be induced by several drugs (epidermal growth factor receptor inhibitors, oral retinoids, sodium valproate, and carbamide perhydrate). The diagnosis of pili torti is based on trichoscopic or microscopic examination. As pili torti is a marker of numerous congenital and acquired disorders, in every case, the search for the signs of underlying conditions is recommended.

Hair disorders

2018 ◽  
Author(s):  
David de Berker
Keyword(s):  
Hair Loss ◽  
Alopecia Areata ◽  
Lupus Erythematosus ◽  
Inflammatory Diseases ◽  
Whole Body ◽  
Discoid Lupus Erythematosus ◽  
Lichen Planopilaris ◽  
Small Areas ◽  
The Family ◽  
Scalp Diseases

This chapter discusses inflammatory scalp diseases and hair shedding (telogen effluvium and pattern hair loss). Inflammatory diseases of the scalp can affect all epidermal surfaces or focus upon the follicle, with relative sparing of the interfollicular skin. Eczema and psoriasis are examples of the former; other diseases, such as lichen planopilaris or discoid lupus erythematosus, are examples of the latter. Some follicular diseases, such as the family of diseases based on alopecia areata (alopecia areata (small areas of hair loss), alopecia totalis (whole scalp), and alopecia universalis (whole body)), cause barely visible follicular inflammation which results in hair loss but no scarring. Some patients present with hair shedding or change of hair pattern as their primary complaint, with no scalp disease; this is telogen effluvium. Others present with an altered pattern of scalp hair without conspicuous shedding; this is pattern hair loss.

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