scholarly journals Neurological and Cardiac Manifestations of Children with Dengue Presenting to a Tertiary Care Institute: An Observational Study

2020 ◽  
Vol 40 (3) ◽  
pp. 224-231
Author(s):  
Jayashree Nadkarni ◽  
Amit Agrawal ◽  
Kiran Shrivastava
Keyword(s):  
Observational Study ◽  
Tertiary Care ◽  
Clinical Manifestations ◽  
Central India ◽  
Neurological Dysfunction ◽  
Tertiary Referral Centre ◽  
Echocardiographic Evaluation ◽  
Atypical Manifestations ◽  
Cardiac Manifestations ◽  
And Control

Introduction: Dengue is a common arboviral infection in tropical areas of world with increased incidence in the past few years. Spread of disease has led to increased recognition of various atypical manifestations apart from the classical features. This study was conducted to find out the neurological and cardiac manifestations of dengue in children. Methods: This observational study was conducted in a tertiary referral centre in Central India. Cases were classified based on the WHO 2009 Dengue guidelines for the diagnosis, treatment, prevention and control. The neurological and cardiac manifestations of dengue were studied and compared with those cases without manifestations. Results: In this study, a total of 75 dengue cases were included and out of them, five (6.75%) cases presented with CNS abnormalities. The most common neurological manifestations were fever with seizures, altered sensorium, vomiting and headache. Hepatomegaly, hypotension, coagulopathy, and leucocytosis (> 11,000 cells/mm3) were significantly associated with neurological dysfunction (p < 0.05). Ten children out of 75 (13.33%) had cardiac manifestations. They included bradycardia in five cases, tachycardia and signs of CCF in three cases and shock in two cases. Echocardiographic evaluation showed mild pericardial effusion in one patient. Conclusions: Dengue poses a huge burden to healthcare system with its various atypical manifestations. A better understanding of neurological and cardiac clinical manifestations of dengue will reduce morbidity and mortality in such cases.

scholarly journals The clinical profile of dengue infection cases presenting in a tertiary care institute: an observational study

2018 ◽  
Vol 5 (6) ◽  
pp. 2294
Author(s):  
Kiran Shrivastava ◽  
Sakshi Ojha ◽  
Jayashree Nadkarni
Keyword(s):  
Observational Study ◽  
Early Recognition ◽  
Dengue Infection ◽  
Tertiary Care ◽  
Central India ◽  
Febrile Illness ◽  
Viral Disease ◽  
Clinical Profile ◽  
Tertiary Referral Centre ◽  
Atypical Symptoms

Background: Dengue is a mosquito-borne viral disease that has rapidly spread in all regions of WHO in recent years. It is an acute febrile illness, caused by infection with any of 4 related positive-sense, single-stranded RNA viruses of the genus Flavivirus, dengue viruses 1, 2, 3, or 4. Objective of study was to study the clinical profile of dengue viral infection in the paediatric age group.Methods: This observational study was conducted in a tertiary referral centre in Central India. Cases were classified based on the WHO 2009 Dengue guidelines for diagnosis, treatment, prevention and control and the clinical and laboratory parameters were analyzed for demographic and other correlates.Results: 75 patients met all the inclusion criteria and were analyzed. Most children were in age group 6-10 years. Fever, bleeding, rash, abdominal pain and vomiting were the common symptoms. We noted some atypical symptoms also.Conclusions: When infected, early recognition and prompt supportive treatment in dengue infection can substantially lower the risk of medical complications and death.

scholarly journals AN OBSERVATIONAL STUDY OF ATYPICAL ECLAMPSIA AND ITS MANAGEMENT IN TERTIARY CARE CENTER OF CENTRAL INDIA

2021 ◽  
Vol 9 (02) ◽  
pp. 659-662
Author(s):  
Aarti Jeenwal ◽  
◽  
Anupama Dave ◽  
Ranjana Patil ◽  
Pooja Gangwar ◽  
...  
Keyword(s):  
Health Care Providers ◽  
Gestational Hypertension ◽  
Care Center ◽  
Tertiary Care ◽  
Clinical Manifestations ◽  
Central India ◽  
Care Providers ◽  
Prodromal Symptoms ◽  
Atypical Form ◽  
Atypical Presentations

Background: Eclampsia is development of convulsions and/or unexplained coma at more than 20 weeks gestation and /or less than 48 hours after delivery.In case if eclampsia occurs before 20 weeks or after 48 hours postpartum or in absence of typical signs of hypertension and/or proteinuria, it is called atypical eclampsia. Diagnosis and management of these cases is a challenge for obstetricians. Method: An observational Prospective study conducted in the Department of Obstetrics and Gynecology, M.G.M. Medical College and M.Y.H. Hospital Indore, from Jan 2019 - Dec 2019. Data was collected regarding the relationship of the patients first seizure to delivery interval, prodromal symptoms, use of magnesium sulfate, antihypertensive therapy and follow up medical care. Results: Total 284 eclampsia patient were admitted in the year, of which 59 (20.7%) of these patient showed atypical feature.Moratlity in eclampsia patient in the year was 34 out of the total 96 maternal death i.e. 35.41% in year. Out of these 34eclamptic deaths, death due to atypical eclampsia was 09 i.e. 26.47%.Main cause of mortality in both eclampsia and atypical form was Pulmonary edema. Conclusion: We recommend that health care providers in obstetric practice should have a high index of suspicion for the potential atypical clinical manifestations of eclampsia, irrespective of gestational age at the time of onset or the number of days after delivery, prodromal symptoms, gestational hypertension or pre eclampsia or proteinuria. Obstetricians should be aware of atypical presentations, maintain a high level of suspicion, and be ready to take immediate steps.

scholarly journals Study of Clinical Findings and Treatment Outcomes of Rhino-OrbitalCerebral Mucormycosis at a Tertiary Care Center in Central India

2021 ◽  
Vol 8 (40) ◽  
pp. 3464-3469
Author(s):  
Kavita Anand Dhabarde ◽  
Pallavi Madhusudan Doble ◽  
Nehali Sureshchandra Pant ◽  
Nisha Vilas Rahul
Keyword(s):  
Treatment Outcomes ◽  
Care Center ◽  
Tertiary Care ◽  
Clinical Manifestations ◽  
Arterial Occlusion ◽  
Central India ◽  
Clinical Findings ◽  
Tertiary Care Center ◽  
Ocular Movements

BACKGROUND Mucormycosis is a potentially lethal angioinvasive fungal infection. Increasing incidence of rhino-orbital-cerebral mucormycosis in setting of corona virus disease-19 (COVID-19) during second wave in India and elsewhere has become a matter of immediate concern. This study was done to assess the clinical findings and treatment outcomes of rhino-orbital-cerebral-mucormycosis presenting to a tertiary care center in central India. METHODS This is a longitudinal study. We observed 38 COVID-19 associated mucormycosis cases. Their demographic data, clinical manifestations, underlying systemic conditions, microbiological and radiological reports, medical treatments and surgical interventions were recorded and analysed. RESULTS Common ocular presenting features were ophthalmoplegia (68 %), proptosis (44 %), periorbital swelling (13 %), diminution of vision (37 %), central retinal arterial occlusion (2.5 %), optic atrophy (2.5 %). Visual acuity at 1 month after surgery was compared with that at presentation and was found unchanged in 27 patients, improved in 3 patients and deteriorated in 6 patients. Functional outcome was evaluated in terms of ocular movements, and it was found that ocular movements were same as presentation in 30 patients, improved in 3 patients and deteriorated in 3 patients at follow up one month after surgery. Radiological outcome was evaluated, and it was found that residual disease was present in 4 patients and absent in 32 patients. Mortality was found in 2 patients at 1 month follow-up period. CONCLUSIONS Early diagnosis, blood sugar levels control, urgent systemic antifungal therapy and sinus debridement surgery are lifesaving in cases of COVID-19 associated mucormycosis. KEYWORDS Mucormycosis, COVID-19, Diabetes Mellitus, Ophthalmoplegia, Orbital Apex Syndrome, Orbital Cellulitis, Proptosis

A Retrospective Observational Study of Poisoning Cases Admitted in a Tertiary Care Teaching Institute in a Tribal Area of Central India

2019 ◽  
Vol 13 (4) ◽  
pp. 113
Author(s):  
Manu D. Sharma ◽  
Lohit S. Vaishnao ◽  
Mahek S. Kewalramani ◽  
Ruchi P. Aggrawal ◽  
Ashutosh S. Jawade ◽  
...  
Keyword(s):  
Observational Study ◽  
Tertiary Care ◽  
Central India ◽  
Retrospective Observational Study ◽  
Care Teaching ◽  
Tribal Area
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