scholarly journals Adverse events following Sinopharm (Vero Cell), the inactivated COVID-19

2021 ◽  
Vol 8 (2) ◽  
pp. 18-24
Author(s):  
Sushant Aryal ◽  
Ranjan Prasad Devbhandari ◽  
Shrijana Shrestha ◽  
Ashis Shrestha ◽  
Piyush Rajbhandari ◽  
...  
Keyword(s):  
Adverse Events ◽  
Vero Cell ◽  
Vaccine Recipient ◽  
Phone Call ◽  
Cell Vaccine ◽  
Study Cohort ◽  
Cross Sectional ◽  
Phone Calls ◽  
Ethical Approval ◽  
Dose Vaccine

Introduction: Various types of COVID 19 vaccine are being used globally to control the current pandemic. Post-licensure surveillance of vaccine is essential to ensure the safety. This study aimed to determine Adverse Events Following Immunization (AEFIs) of China Sinopharm (Vero cell), the inactivated COVID-19 vaccine. Method: This is a cross sectional observational study conducted at Patan hospital, Patan Academy of Health Sciences (PAHS) after the approval from IRC. Vaccine recipient between April 7 to April 13 and May 16 to May 25 were contacted through a phone call after 72 h of vaccination to record the AEFIs. Pattern and distribution of AEFIs were analyzed. Ethical approval was taken from PAHS IRC. Result: A total of 6142 individual got the first dose of the vaccine and out of them we were able to contact 4574 through phone calls. Of the 4574, only 941 were included for the follow up phone call after the second dose of the vaccine. A total of 1336 AEFIs were reported in 868(19%) first dose vaccine recipients while 147 AFEIs were reported in 105(11.2%) second dose vaccine recipients.  The frequently reported AEFIs were pain at injection site, lethargy, headache, muscle ache and fever. All the AEFIs were mild to moderate in severity. Most of the AEFIs started within 24 h and resolved within 72 h. Conclusion: The Sinopharm (Vero cell) vaccine was found to have mild to moderate AEFIs in our study cohort and no case of severe AEFI was identified.

scholarly journals Comprehensive Cervical Cancer Prevention in Tanzania (CONCEPT) study: Cohort profile

BMJ Open ◽  
2020 ◽  
Vol 10 (9) ◽  
pp. e038531
Author(s):  
Bariki Mchome ◽  
Patricia Swai ◽  
Chunsen Wu ◽  
Johnson Katanga ◽  
Crispin Kahesa ◽  
...  
Keyword(s):  
Cervical Cancer ◽  
Cancer Prevention ◽  
Cervical Cancer Prevention ◽  
Eastern Africa ◽  
Phone Call ◽  
Hiv Positive ◽  
Study Cohort ◽  
Cross Sectional ◽  
Concept Study

PurposeCervical cancer is a major cause of death among women in Eastern Africa, and the distribution of human papillomavirus (HPV) according to HIV status is inadequately characterised in this region. In order to guide future cervical cancer preventive strategies that involve HPV testing, the Comprehensive Cervical Cancer Prevention in Tanzania (CONCEPT) study was established in 2015. The CONCEPT cohort aims to investigate the natural history of HPV and determine acquisition and persistence patterns of high-risk (HR) HPV among HIV-positive and HIV-negative women. Further, the influence of lifestyle and sexual/reproductive factors will be investigated. The main objective of this article is to describe how the CONCEPT cohort was established.ParticipantsWomen aged 25–60 years were enrolled from cervical cancer screening clinics in Dar-es-Salaam and Moshi, Tanzania. Data were collected at baseline, at 14 months (first follow-up) and at 28 months (second follow-up). Biological samples included two cervical swabs for careHPV DNA testing, cytology, Hybrid Capture 2, genotyping and blood samples for HIV. Visual inspection with acetic acid was performed, and sociodemographic, lifestyle and sexual/reproductive characteristics were collected through a standardised questionnaire.Findings to date4043 women were included in the cohort from August 2015 to May 2017. At baseline, 696 (17.1%) women were HR HPV positive, and among these, 31.6% were HIV positive; 139 women (3.4%) had high-grade squamous intraepithelial lesions. 3074 women (81%) attended the first follow-up. The majority attended after receiving a phone call reminder (35%) or from home via self-samples (41%). At first follow-up, 438 (14.4%) were HR HPV positive and 30.4% of these were HIV positive.Future plansA second follow-up is underway (17 December 2018–October 2020). We plan to integrate our data with a previous cross-sectional HPV study from Tanzania to increase the power of our findings. Researchers interested in collaborating are welcomed, either by extracting data or jointly requesting further investigation from the cohort.

scholarly journals Hemispheric Dominance and Laterality in Mobile Phone Use in Adults: An Observational Study

2019 ◽  
pp. 1-9
Author(s):  
N. C. Onyeagwara ◽  
A. L. Okhakhu
Keyword(s):  
Mobile Phone ◽  
Cell Phone ◽  
Phone Call ◽  
Hemispheric Dominance ◽  
Cross Sectional ◽  
Survey Tool ◽  
Mobile Phone Use ◽  
Phone Calls ◽  
Right Hand ◽  
The Right

Aims: Mobile/cell phone use has become an important socio-medical means of communication. The reason people use a particular ear to answer phone calls more frequently may be associated with hemispheric dominance/ handedness. We aim to determine association between hemispheric and or auditory dominance in laterality in mobile phone use.    Study Design:  This was a three month prospective cross-sectional study involving all consenting medical and paramedical respondents. Place and Duration of Study: Hospital community in the University of Benin Teaching Hospital (UBTH), Benin City , between 15th March to 15th June 2018. Method: A modification of the Edinburgh handedness inventory (EHI) was the survey tool. Information retrieved included social demographics, hand most commonly used for activities like writing and picking of phone calls and ear used for phone conversation and the reasons. Data was analyzed using SPSS 19.0 Results: Of the 300 questionnaires distributed, 234 (78%) were completed by the respondents. There were 120(51.3%) males and114 (48.7%) females.  Age ranged from 18 - 80years. A total of 201(85.9%) were right handed, 16(6.8%) left handed and 14(6.0%) ambidextrous. One hundred and fifty four (66%) routinely use their right hand to pick phone calls, 50(21.4%) left and 27 (11.5%) use both hands. A total of 141(60%) receive calls with the right ear, 60 (25.6%) with left, and 31(13.2%) had no preference.  Reasons advanced for the use of any particular ear included convenience 173 (73.9%), and better acuity 35(15%). Forty two (17.9%) agreed that the use of cell phone made them aware of their poor hearing in a particular ear. Using Pearson’s two tailed test of significance the probability of a right hander using the right hand to pick a phone call and placing it on the right ear is 0.99 or 99%, Vis a Vis left hander. Conclusion: There appears to be an association between hemispheric dominance and laterality when using the mobile phone.

scholarly journals Effects of the COVID-19 pandemic on the follow-up and treatment of patients with idiopathic pulmonary fibrosis: a cross-sectional, multicentre phone call survey

BMJ Open ◽  
2021 ◽  
Vol 11 (8) ◽  
pp. e050578
Author(s):  
Funda Coskun ◽  
Ismail Hanta ◽  
Aykut Cilli ◽  
Guven Ozkaya ◽  
Ahmet Ursavas ◽  
...  
Keyword(s):  
Idiopathic Pulmonary Fibrosis ◽  
Pulmonary Fibrosis ◽  
Significant Proportion ◽  
Phone Call ◽  
Drug Discontinuation ◽  
Blood Testing ◽  
Cross Sectional ◽  
Routine Blood ◽  
Phone Calls ◽  
Anxiety Depression

ObjectiveTo learn about the attitudes and behaviours of patients with idiopathic pulmonary fibrosis (IPF) in relation to the difficulties experienced during the COVID-19 pandemic.DesignA cross-sectional, multicentre phone call survey.SettingFour university hospitals in Turkey.ParticipantsThe study included patients with IPF receiving antifibrotics for at least 3 months and with doctor appointment and/or scheduled routine blood analysis between March and May 2020 (the first 3 months after the official announcement of the COVID-19 pandemic in Turkey).InterventionsPhone calls (a 5 min interview) were performed in June 2020. A questionnaire and the Hospital Anxiety-Depression Scale were applied.Main outcome measuresPatients’ preferences for disease monitoring, patients’ attitudes and behaviours towards IPF, drug continuation, COVID-19 diagnosis and anxiety/depression status.ResultsThe study included 115 patients with IPF (82 male; mean age, 68.43±7.44 years). Of the patients, 73.9% had doctor appointment and 52.2% had scheduled routine blood testing; 54.5% of patients with doctor appointment self-cancelled their appointments and 53.3% of patients with scheduled routine blood testing did not undergo testing. Of the patients, 32.2% were on nintedanib and 67.8% were on pirfenidone; self-initiated drug discontinuation rate was 22.6%. The percentage of patients communicating with their physicians was 35.7%. The route of communication was by phone (34.8%). The frequency of depression and anxiety was 27.0% and 38.3%, respectively. The rates of drug discontinuation (35.1% vs 16.7%, p<0.05) and depression (37.8% vs 21.8%, p=0.07) were higher in nintedanib users than in pirfenidone users. Only two (1.7%) patients had COVID-19 diagnosis.ConclusionsDuring the COVID-19 pandemic, a significant proportion (>50%) of patients self-cancelled their appointments and nearly a quarter of patients discontinued their medications. Providing a documentation of the problems experienced by patients with IPF about management of the necessary requirements during the COVID-19 pandemic, this study may be a model for patients with chronic diseases.

Do mothers pick up a phone? A cross-sectional study on utilizations of MCH voice messages in Lagos, Nigeria (Preprint)

2021 ◽  
Author(s):  
Kazuya Ogawa ◽  
Yoshito Kawakatsu ◽  
Nobuhiro Kadoi ◽  
Olukunmi Omobolanle Balogun ◽  
Adefunke Oyeniyi Adesina ◽  
...  
Keyword(s):  
Intervention Program ◽  
Cross Sectional Study ◽  
Phone Call ◽  
Cross Sectional ◽  
The Core ◽  
Phone Calls ◽  
Message Service ◽  
Voice Message ◽  
The Voice ◽  
Core Message

BACKGROUND Voice messages have been employed as the effective and efficient means for increasing health service utilizations and health promotion in low- and middle-income countries. Yet, unlike SMS, voice message services require their users to pick up a phone call at the time of its delivery. Furthermore, voice messages are difficult for the users to review their contents afterwards. While recognizing that voice messages are more friendly to specific groups (eg, illiterate or less literate populations), there should be several challenges in successfully operationalizing its intervention program. OBJECTIVE This study is aimed at estimating the extent to which voice message service users pick up the phone calls of voice messages and complete listening up to or beyond the core part of voice messages. METHODS A voice message service program composed of 14 episodes on maternal, newborn and child health was piloted in Lagos, Nigeria, during the period from 2017 to 2019. A voice message call of each of 14 episodes was delivered to the mobile phones of the program participants, per day for 14 consecutive days. A total of 513 participants in the voice message service chose one of five locally spoken languages as the language to be used for voice messages. Two multilevel logistic regression models were created: (1) Model 1 for testing whether a voice message call is picked up; and (2) Model 2 for testing whether a voice message call having been picked up is listened to up to the core messaging part. RESULTS The greater the voice message episode number became, the smaller proportion of the participants picked up the phone calls of voice message (aOR: 0.98; 95% CI: 0.97-0.99; P=.01). Only 854 of 3765voice message calls having been picked up by the participants (22.7%) were listened to up to their core message parts. It was found that the level of sequentiality between picking up a phone call of a voice message and listening up to the core message part was low. This indicates discontinuity between these two actions. CONCLUSIONS The participants were likely to stop picking up the phone as the episode number of voice messages progressed. In view of discontinuity and independence between picking up a phone call and listening up to the core message part, we should not assume that those picking up the phone would automatically complete listening to the entire or core voice message.

scholarly journals Adverse events following the first dose of ChAdOx1 nCoV-19 (COVISHIELD) vaccine in the first phase of vaccine roll out in Nepal

2021 ◽  
Vol 8 (1) ◽  
pp. 9-17
Author(s):  
Shrijana Shrestha ◽  
Ranjan Prasad Devbhandari ◽  
Ashis Shrestha ◽  
Sushant Aryal ◽  
Piyush Rajbhandari ◽  
...  
Keyword(s):  
Adverse Events ◽  
Past History ◽  
Symptom Relief ◽  
Age Groups ◽  
Previous History ◽  
Phone Call ◽  
Self Medication ◽  
Phone Calls ◽  
History Of ◽  
Frontline Healthcare Workers

Introduction: Nepal started the first phase of COVID-19 vaccination for frontline healthcare workers in January 2021 with the ChAdOx1 nCoV-19 (COVISHIELD) vaccine. We conducted active surveillance of Adverse Effect Following Immunization (AEFI) after the first dose of the vaccine administered at one of the sentinel sites for vaccination, Patan Academy of Health Sciences (PAHS). Method:  All the 5591 first dose ‘COVISHIELD’ vaccine recipients between 27 Jan -5 Feb 2021 at PAHS, were approached through phone calls to collect data on AEFI.  Incidence of common AEFIs in different age groups, gender and those with previous history of COVID-19 were analyzed. Presence of any Adverse Events of Special Interest (AESI) were evaluated. Result: Out of 5591 vaccines recipient, 3991 (71.3%) responded to the phone call and AEFI was noted in 3394 (85.04%) of them. Minor AEFI was seen in 3391 (84.9%), severe Minor AEFI in 1 (0.02%) and Serious AEFI in 2 (0.05%). Out of 807 vaccine recipients with previous history of COVID-19, 709 (87.9%) had AEFI while of the 3184 with no past history of COVID-19, 2685 (84.3%) had AEFI. However, some of the systemic AEFIs were noted more frequently in those with past COVID-19 infection. A total of 1886 (55.6%) took self-medication for symptom relief, 278 (8.2%) took leave from work while 26 (0.76%) visited health facility for the AEFIs. Conclusion:  Most AEFIs following the first dose of COVISHIELD vaccine were mild and resolved within a few days. Except for one case of anaphylaxis, no other AESI were encountered.

Post-Hospital Syndrome (PHS) and Potentially Preventable Hospitalizations(PPH) in Adults. MonashWatch adult cohort patient telehealth journeys (Preprint)

2018 ◽  
Author(s):  
Associate Professor Martin ◽  
Narelle Hinckley ◽  
Keith Stockman ◽  
Donadl Campbell
Keyword(s):  
Adverse Outcomes ◽  
Phone Call ◽  
Post Discharge ◽  
Patient Journey ◽  
Preventable Hospitalizations ◽  
Acute Admission ◽  
Avoidable Hospitalizations ◽  
Self Rated Health ◽  
Phone Calls ◽  
Potentially Preventable Hospitalizations

BACKGROUND Monash Watch (MW) aims to reduce avoidable hospitalizations in a cohort above a risk ‘threshold’ identified by HealthLinks Chronic Care (HLCC) algorithms using personal, diagnostic, and service data, excluding surgical and psychiatric admissions. MW conducted regular patient monitoring through outbound phone calls using the Patient Journey Record System (PaJR). PaJR alerts are intended to act as a self-reported barometer of health perceptions with more alerts per call indicating greater risk of Potentially Preventable Hospitalizations (PPH) and Post Hospital Syndrome (PHS). Most knowledge of PPH and PHS occurs at a macro-level with little understanding of fine-grained dynamics. OBJECTIVE To describe patterns of self-reported concerns and self-rated health 10 days before and after acute hospital admission in the telehealth intervention cohort of MonashWatch in the context of addressing PPH and PHS. METHODS Participants: 173 who had an acute admission of the of the 232 HLCC cohort with predicted 3+ admissions/year, in MW service arm for >40 days. Measures: Self-reported health and health care status in 764 MW phone call records which were classified into Total Alerts (all concerns - self-reported) and Red Alerts (concerns judged to be higher risk of adverse outcomes/admissions -acute medical and illness symptoms). Acute (non-surgical) admissions from Victorian Admitted Episode database. Analysis: Descriptive Timeseries homogeneity metrics using XLSTAT. RESULTS Self-reported problems (Total Alerts) statistically shifted to a higher level 3 days before an acute admission and stayed at a high level for the 10 days post discharge; reported acute medical and illness symptoms (Red Alerts) increased 1 day prior to admission and but remained at a higher level than before admission. Symptoms of concern did not change before admission or after discharge. Self-rated health and feeling depressed were reported to worsen 5 days post discharge. Patients reported more medication changes up to 2 days before acute admission. CONCLUSIONS These descriptive findings in a cohort of high risk individuals suggest a prehospital phase of what is termed PHS, which persisted on discharge and possibly worsened 5 days after discharge with worse self-rated health and depressive symptoms. Further research is needed. The role and place of community and hospital in such a cohort needs further investigation and research into PPH and PHS.

scholarly journals Adverse Events in Home-Care Nursing Agencies and Related Factors: A Nationwide Survey in Japan

2021 ◽  
Vol 18 (5) ◽  
pp. 2546
Author(s):  
Noriko Morioka ◽  
Masayo Kashiwagi
Keyword(s):  
Adverse Event ◽  
Patient Safety ◽  
Adverse Events ◽  
Home Care ◽  
Process Of Care ◽  
Related Factors ◽  
Cross Sectional ◽  
Home Care Nursing ◽  
Number Of Patients ◽  
Care Nursing

Despite the importance of patient safety in home-care nursing provided by licensed nurses in patients’ homes, little is known about the nationwide incidence of adverse events in Japan. This article describes the incidence of adverse events among home-care nursing agencies in Japan and investigates the characteristics of agencies that were associated with adverse events. A cross-sectional nationwide self-administrative questionnaire survey was conducted in March 2020. The questionnaire included the number of adverse event occurrences in three months, the process of care for patient safety, and other agency characteristics. Of 9979 agencies, 580 questionnaires were returned and 400 were included in the analysis. The number of adverse events in each agency ranged from 0 to 47, and 26.5% of the agencies did not report any adverse event cases. The median occurrence of adverse events was three. In total, 1937 adverse events occurred over three months, of which pressure ulcers were the most frequent (80.5%). Adjusting for the number of patients in a month, the percentage of patients with care-need level 3 or higher was statistically significant. Adverse events occurring in home-care nursing agencies were rare and varied widely across agencies. The patients’ higher care-need levels affected the higher number of adverse events in home-care nursing agencies.

Patient Education and Sacubitril/Valsartan: A Randomized Comparative Trial

2021 ◽  
pp. 001857872199980
Author(s):  
Christopher Giuliano ◽  
Bradley St. Pierre ◽  
Jamie George
Keyword(s):  
Controlled Trial ◽  
Comparative Trial ◽  
Text Messages ◽  
Phone Call ◽  
Secondary Outcome ◽  
Short Term ◽  
Phone Calls ◽  
Video Education ◽  
Pharmacist Education

Objective: To compare video to pharmacist education for patients taking sacubitril/valsartan. Methods: We conducted a randomized controlled trial comparing video to pharmacist education with a second randomized intervention of education delivered through text or phone call at 14 days. The primary outcome compared the change in short term knowledge between groups and the secondary outcome was long term knowledge at 1 month. Results: Forty-three patients were included. Scores improved significantly ( P < .05) in the pharmacist group from 54.1% to 85.9% and from 64.3% to 86.1% in the video education group, although there was no difference between groups (31.8% vs 22.9%, P = .13). At 30 days, scores were significantly higher than baseline (difference 16.5%, P < .05) although did decrease from the posttest (difference 7.4%, P < .05). There was no difference at 30 days between those that received text messages versus phone calls (−10% vs −5.5%, respectively; P = .36). Conclusion: We saw improvements in both short term and long term knowledge for patients receiving education through pharmacist or video education. Neither approach was more effective than the other. Clinicians can use either approach based on patient preference.

scholarly journals Mediterranean Diet and Healthy Eating in Subjects with Prediabetes from the Mollerussa Prospective Observational Cohort Study

Nutrients ◽  
2021 ◽  
Vol 13 (1) ◽  
pp. 252
Author(s):  
Mireia Falguera ◽  
Esmeralda Castelblanco ◽  
Marina Idalia Rojo-López ◽  
Maria Belén Vilanova ◽  
Jordi Real ◽  
...  
Keyword(s):  
Glucose Tolerance ◽  
Mediterranean Diet ◽  
Healthy Eating ◽  
Dietary Patterns ◽  
Normal Glucose Tolerance ◽  
Healthy Eating Index ◽  
Study Cohort ◽  
Cross Sectional ◽  
Normal Glucose ◽  
Multivariable Analyses

We aimed to assess differences in dietary patterns (i.e., Mediterranean diet and healthy eating indexes) between participants with prediabetes and those with normal glucose tolerance. Secondarily, we analyzed factors related to prediabetes and dietary patterns. This was a cross-sectional study design. From a sample of 594 participants recruited in the Mollerussa study cohort, a total of 535 participants (216 with prediabetes and 319 with normal glucose tolerance) were included. The alternate Mediterranean Diet score (aMED) and the alternate Healthy Eating Index (aHEI) were calculated. Bivariable and multivariable analyses were performed. There was no difference in the mean aMED and aHEI scores between groups (3.2 (1.8) in the normoglycemic group and 3.4 (1.8) in the prediabetes group, p = 0.164 for the aMED and 38.6 (7.3) in the normoglycemic group and 38.7 (6.7) in the prediabetes group, p = 0.877 for the aHEI, respectively). Nevertheless, women had a higher mean of aMED and aHEI scores in the prediabetes group (3.7 (1.9), p = 0.001 and 40.5 (6.9), p < 0.001, respectively); moreover, they had a higher mean of aHEI in the group with normoglycemia (39.8 (6.6); p = 0.001). No differences were observed in daily food intake between both study groups; consistent with this finding, we did not find major differences in nutrient intake between groups. In the multivariable analyses, the aMED and aHEI were not associated with prediabetes (odds ratio (OR): 1.19, 95% confidence interval (CI): 0.75–1.87; p = 0.460 and OR: 1.32, 95% CI: 0.83–2.10; p = 0.246, respectively); however, age (OR: 1.04, 95% CI: 1.02–1.05; p < 0.001), dyslipidemia (OR: 2.02, 95% CI: 1.27–3.22; p = 0.003) and body mass index (BMI) (OR: 1.09, 95% CI: 1.05–1.14; p < 0.001) were positively associated with prediabetes. Physical activity was associated with a lower frequency of prediabetes (OR: 0.48, 95% CI: 0.31–0.72; p = 0.001). In conclusion, subjects with prediabetes did not show a different dietary pattern compared with a normal glucose tolerance group. However, further research is needed on this issue.

Sign in / Sign up

Export Citation Format

Share Document