scholarly journals Treatment Non-Compliance In Patients Suffering From Schizophrenia And Bipolar Affective Disorder (BPAD): A Comparative Study

2019 ◽  
Vol 8 (2) ◽  
pp. 20-25
Author(s):  
K. Paudel ◽  
S. Subedi
Keyword(s):  
Psychiatric Disorders ◽  
Affective Disorder ◽  
Quality Care ◽  
Bipolar Affective Disorder ◽  
Cross Sectional Study ◽  
Cross Sectional ◽  
Active Involvement ◽  
Interview Method ◽  
Adherence Scale ◽  
Bipolar Affective Disorders

 Introduction: Non-adherence to appropriately prescribed medication for psychiatric disorders prevents patients from realizing the full benefits of their treatment and negatively impacts on individuals, their families and the healthcare system. Understanding and reducing non-adherence is therefore a key challenge to quality care for patients with psychiatric disorders. This finding highlights the prevalence, consequence of non-adherence and barriers to adherence. Therefore, the main objective of this study was to determine the incidence and factors associated with medication non-compliance among patients suffering from schizophrenia and bipolar affective disorders. Material and Method: This cross-sectional study included 94 schizophrenia and 76 bipolar affective disorder subjects who were visited psychiatric OPD of tertiary level hospital and disproportionate stratified random sampling method. An anonymous socio-demographic as well contributing factor questionnaire pre tested, semi structured pro forma by interview method and a clinical proforma designed by Morisky, the 8-item Morisky Medication Adherence Scale (MMAS-8) were used for data collection. Results: The prevalence of non-compliance was 88%, the independent predictors of non-compliance were; seeking for traditional/spiritual treatment, weight gain as side effects of drugs , increased number of medication (p=0.038), beginning of medication start (p=0.057), unemployment (p=0.059), low level of insight/education (p=0.044), male as gender (p=0.016). Conclusion: Based on the outcome of the study, we recommend the development of psycho-educational programmes on compliance and the active involvement of the relatives and significant others in the management of patients of mentally ill patients.

Treatment Non-Compliance in Patients with Schizophrenia

2020 ◽  
Vol 8 (1) ◽  
pp. 3-8
Author(s):  
Sandip Subedi ◽  
Kamala Paudel ◽  
Dev Kumar Thapa
Keyword(s):  
Negative Impact ◽  
Economic Status ◽  
Demographic Data ◽  
Quality Care ◽  
Compliance Rate ◽  
Cross Sectional Study ◽  
Data Sheet ◽  
Cross Sectional ◽  
Active Involvement ◽  
Adherence Scale

INTRODUCTION: Non-compliance to medication in Schizophrenia is a common problem.  It leads to frequent recurrence of Psychosis which has negative impact on individuals and their families. Understanding and reducing non-adherence is therefore a key challenge to quality care for patients with Schizophrenia. This study was conducted with the aim of determining the incidence and factors associated with medication non-compliance among patients suffering from schizophrenia. MATERIAL AND METHODS: This cross-sectional study included 94 schizophrenic subjects who visited psychiatric OPD of tertiary level hospital. Disproportionate stratified random sampling method was applied to collect the data. Socio-demographic data sheet, data sheet to collect the various factors of compliance and the 8-item Morisky Medication Adherence Scale (MMAS-8) were used for data collection by interview method.  RESULTS: The prevalence of non-compliance was 89.4%. With regards to association between noncompliance and demographic characteristics, there was high non-compliance rate in age below 40 years (54.2%), male (52.1%), married (64.8%) and low economic status (52%). Medication non-compliance were high in patients with medication side effects dizziness (60.6%), sedation (66%), longer duration of illness (92.8%) & having 1-3 pills (47.8%). CONCLUSION: Medication Non-Compliance in Schizophrenia was high. Measures that can increase compliance like psycho-educational programmes on compliance and the active involvement of the relatives and significant others in the management of patients of mentally ill patients are recommended.

scholarly journals Treatment Non-Compliance in Bipolar Affective Disorder Patients: A Study from a Tertiary Care Centre in Nepal

2020 ◽  
Vol 3 (1) ◽  
Author(s):  
Sandip Subedi ◽  
Kamala Paudel
Keyword(s):  
Affective Disorder ◽  
Bipolar Affective Disorder ◽  
Tertiary Care ◽  
Previous Treatment ◽  
Cross Sectional Study ◽  
Contributing Factors ◽  
Tertiary Care Centre ◽  
Cross Sectional ◽  
Duration Of Illness ◽  
Adherence Scale

Background: Treatment Non-compliance is a major challenge in the treatment of Bipolar Affective Disorder as it can give rise to lots of unwanted consequences. Therefore, understanding various reasons for non-compliance and taking steps to reduce it is a key step in minimizing the unwanted consequences. Thus, This study was done to identify the pattern of non-compliance in patients with Bipolar Affective Disorder. Methods: This was a cross-sectional study including 76 patients who attended Psychiatry OPD of Universal College of Medical Sciences. Socio-demographic datasheet, Datasheet for various factors related to non-compliance, Morisky 8-Item Medication Adherence Scale (MMAS-8) and Descriptive summaries of socio-demographic and contributing factors for all patients were used to record the data. Results: Out of a total of 76 patients, males (55.2%) were slightly higher than Females. The mean age of participants was 35.78±12.25 years.  About 76.8% of the patients were non-compliant. High non-compliance was seen in age below 40 years (48.7%), male (52.6%) and duration of illness up to 15 years (78.9%), having up to 3 pills (44.7%) and having previous treatment history (60.5%). Conclusion: Treatment non-compliance was very high in patients with BPAD. Appropriate measures need to be taken care of to reduce non-compliance.

COMPARING SOCIOEMOTIONAL COGNITION AND QUALITY OF LIFE IN REMITTED BIPOLAR AFFECTIVE DISORDER

2021 ◽  
pp. 18-22
Author(s):  
Nimitha K J ◽  
Rajmohan V ◽  
T M Raghuram
Keyword(s):  
Quality Of Life ◽  
Affective Disorder ◽  
Psychosocial Functioning ◽  
Emotional Regulation ◽  
Economic Status ◽  
Bipolar Affective Disorder ◽  
Cross Sectional Study ◽  
Social Emotional ◽  
Cross Sectional

BACKGROUND-Bipolar affective disorder (BPAD) is characterized by abnormalities in social cognition and emotional regulation are detrimental to psychosocial functioning and quality of life. OBJECTIVES- To understand the sociodemographic background, clinical characteristics in BPAD in remission and its relation with social emotional cognition and its impact on quality of life and functioning of the patient. METHODS-A cross sectional study with a sample size of 100 consenting patients based on convenience sampling who are diagnosed to have BPAD in remission. Sociodemographic questionnaire and clinical details of the patient were noted. SECT (cog state battery) was applied to all patients under calm and similar environment. RESULTS-Results showed there is a signicant difference in SECTspeed, response and stimuli based on the nature of rst and last episode, SECT score based on severity of episodes, SECT speed and stimuli based on education, SECT responses based on occupation. Middle socio-economic group had the best psychological QoL followed by high socio-economic group and it was worst in low socio-economic group. Physical and psychological domain has signicant difference based on residence. WHO QoL social quality of life had signicant difference between ECT treatments in the past, with people receiving ECT having a higher score on the social QoLscore. There was no signicant correlation seen between SEC sub scores and QoLdomain scores. CONCLUSION-The study concluded the QoLwas signicantly associated with socio-economic status, semi urban residence and ECT. There was no correlation between SEC and QoLscore in remitted bipolar.

scholarly journals Affective and Psychotic Disorders in War-Torn Eastern Part of the Democratic Republic of the Congo: A Cross-Sectional Study

2020 ◽  
Vol 2020 ◽  
pp. 1-7
Author(s):  
Bives Mutume Vivalya ◽  
Germain Manzekele Bin Kitoko ◽  
Adelard Kalima Nzanzu ◽  
Martial Mumbere Vagheni ◽  
Rock Kasereka Masuka ◽  
...  
Keyword(s):  
Psychotic Disorders ◽  
Democratic Republic ◽  
Bipolar Affective Disorder ◽  
Traumatic Events ◽  
Cross Sectional Study ◽  
Traumatic Experiences ◽  
Cross Sectional ◽  
Lack Of Information ◽  
Republic Of The Congo ◽  
Bipolar Affective Disorders

Background. There is lack of information about prevalence of affective and psychotic disorders triggered by traumatic events among people living in war-affected regions. This study is aimed at determining the prevalence rate of affective and psychotic disorders and the associated factors in a war-torn eastern part of Democratic Republic of the Congo. Methods. This epidemiological cross-sectional descriptive study was carried out from 1st January 2019 to 31st December 2019 at Cepima and Muyisa health centers. This study enrolled 344 patients that had experienced traumatic events in Eastern Democratic Republic of the Congo from the 1119 participants, of whom 229 had positive bipolar affective disorder and 115 patients had psychotic disorders. Results. The results revealed that bipolar affective disorders were two times more than psychotic disorders. Sexual abuse, sudden death of a relative, kidnapping, the physical torture, and childhood trauma were the psychological factors correlated to the occurrence of bipolar affective and psychotic disorders. Conclusions. It was concluded that the traumatic experiences were precursors for the occurrence of bipolar affective and psychotic spectrum disorders.

PERIPHERAL NON_ ENZYMATIC ANTIOXIDANTS LEVELS IN SCHIZOPHRENIA AND BIPOLAR ILLNESS A COMPARATIVE CROSS-SECTIONAL STUDY

2021 ◽  
Vol 5 (8) ◽  
Author(s):  
Rajendra Kumar Acharya ◽  
Rahul Gupta ◽  
Sanjay Gehlot
Keyword(s):  
Oxidative Stress ◽  
Uric Acid ◽  
Affective Disorder ◽  
Bipolar Affective Disorder ◽  
Cross Sectional Study ◽  
Enzymatic Antioxidants ◽  
Sectional Study ◽  
Cross Sectional ◽  
Bipolar Illness ◽  
Nonenzymatic Antioxidants

Background: Nervous tissue is extremely sensitive to oxidative damage Recent studies show an elevated level of oxidative stress indicators in Schizophrenia. Current studies on oxidative stress in Schizophrenia mainly focus on enzymatic antioxidants, while limited studies have been carried out on non-enzymatic antioxidants Some studies discovered that plasma non-enzymatic antioxidants (uric acid, bilirubin, and albumin) in Schizophrenia are lower than those of healthy controls. Aim: To compare levels of nonenzymatic antioxidants in Schizophrenia and bipolar illness. Material and Methods: The present study is a hospital_ based cross-sectional study conducted among 100 patients with Schizophrenia and Bipolar Affective disorder included as per inclusion and exclusion criteria and undergone psychiatric assessment as per diagnostic criteria. Results: S. albumin, S.bilirubin, S.uric acid were found to be low in Schizophrenia but statistically, the significant difference was evaluated for S.uric acid. Conclusion: S. uric acid lower significant levels in Schizophrenia as compared to bipolar affective disorder shows the more impaired peripheral antioxidant scavenging system in Schizophrenia. However, pure peripheral antioxidant system dysfunction could not be ascertained in Schizophrenia through this study. Keywords: nonenzymatic antioxidants, Schizophrenia, bipolar illness.

scholarly journals Assessing Caregiver Burden in Caregivers of Patients with Schizophrenia and Bipolar Affective Disorder in Kathmandu Medical College

2018 ◽  
Vol 15 (3) ◽  
pp. 258-263 ◽  
Author(s):  
Rachana Sharma ◽  
Subhash Chandra Sharma ◽  
Sudarshan N Pradhan
Keyword(s):  
Affective Disorder ◽  
Bipolar Affective Disorder ◽  
Cross Sectional Study ◽  
Subjective Feeling ◽  
Cross Sectional ◽  
Term Care ◽  
Psychological Burden ◽  
Medical College ◽  
Duration Of Illness

Background: Schizophrenia and bipolar affective disorder are chronic psychiatric illness that requires long term care. This study tends to measure psychological burden and factors associated with it among caregivers of these two illnesses.Methods: This is a cross- sectional study that included participants by purposive sampling method. Self designed performa was used to collect the socio-demographic details of the caregivers. Modified caregiver strain index was used to assess the overall stress. Beck`s depression inventory and Beck`s anxiety inventory was used to assess depression and anxiety respectively.Results: Hundred caregivers, 50 each of schizophrenia and bipolar affective disorder were enrolled. Seventy-two percent of caregivers were found to have higher level of stress. Twenty-five percent had depression and 29% anxiety related problems. Stress was found to be significantly associated with being in debt, longer duration of illness, education level, marital status, subjective feeling of psychological stress and self- acknowledgement of need of professional help. Caregivers of both group experienced similar level of stress.Conclusions: Psychological burden is seen to be high in caregivers of patients of Schizophrenia and Bipolar Affective Disorder.

Do treatment and illness beliefs influence adherence to medication in patients with bipolar affective disorder? A preliminary cross-sectional study

2010 ◽  
Vol 25 (4) ◽  
pp. 216-219 ◽  
Author(s):  
R. Hou ◽  
V. Cleak ◽  
R. Peveler
Keyword(s):  
Affective Disorder ◽  
Bipolar Affective Disorder ◽  
Cross Sectional Study ◽  
Illness Beliefs ◽  
Sectional Study ◽  
Cross Sectional ◽  
Adherence To Medication ◽  
Suitable Target ◽  
Predictors Of Adherence

AbstractAdherence to medication is essential for achieving good outcomes for patients with bipolar affective disorder. This study tested whether treatment and illness beliefs are important predictors of adherence to medication. Results indicate that beliefs are predictive, and may be a suitable target for modification in efforts to change behaviour.

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