Treatment Non-Compliance in Patients with Schizophrenia

2020 ◽  
Vol 8 (1) ◽  
pp. 3-8
Author(s):  
Sandip Subedi ◽  
Kamala Paudel ◽  
Dev Kumar Thapa

INTRODUCTION: Non-compliance to medication in Schizophrenia is a common problem.  It leads to frequent recurrence of Psychosis which has negative impact on individuals and their families. Understanding and reducing non-adherence is therefore a key challenge to quality care for patients with Schizophrenia. This study was conducted with the aim of determining the incidence and factors associated with medication non-compliance among patients suffering from schizophrenia. MATERIAL AND METHODS: This cross-sectional study included 94 schizophrenic subjects who visited psychiatric OPD of tertiary level hospital. Disproportionate stratified random sampling method was applied to collect the data. Socio-demographic data sheet, data sheet to collect the various factors of compliance and the 8-item Morisky Medication Adherence Scale (MMAS-8) were used for data collection by interview method.  RESULTS: The prevalence of non-compliance was 89.4%. With regards to association between noncompliance and demographic characteristics, there was high non-compliance rate in age below 40 years (54.2%), male (52.1%), married (64.8%) and low economic status (52%). Medication non-compliance were high in patients with medication side effects dizziness (60.6%), sedation (66%), longer duration of illness (92.8%) & having 1-3 pills (47.8%). CONCLUSION: Medication Non-Compliance in Schizophrenia was high. Measures that can increase compliance like psycho-educational programmes on compliance and the active involvement of the relatives and significant others in the management of patients of mentally ill patients are recommended.

2019 ◽  
Vol 8 (2) ◽  
pp. 20-25
Author(s):  
K. Paudel ◽  
S. Subedi

 Introduction: Non-adherence to appropriately prescribed medication for psychiatric disorders prevents patients from realizing the full benefits of their treatment and negatively impacts on individuals, their families and the healthcare system. Understanding and reducing non-adherence is therefore a key challenge to quality care for patients with psychiatric disorders. This finding highlights the prevalence, consequence of non-adherence and barriers to adherence. Therefore, the main objective of this study was to determine the incidence and factors associated with medication non-compliance among patients suffering from schizophrenia and bipolar affective disorders. Material and Method: This cross-sectional study included 94 schizophrenia and 76 bipolar affective disorder subjects who were visited psychiatric OPD of tertiary level hospital and disproportionate stratified random sampling method. An anonymous socio-demographic as well contributing factor questionnaire pre tested, semi structured pro forma by interview method and a clinical proforma designed by Morisky, the 8-item Morisky Medication Adherence Scale (MMAS-8) were used for data collection. Results: The prevalence of non-compliance was 88%, the independent predictors of non-compliance were; seeking for traditional/spiritual treatment, weight gain as side effects of drugs , increased number of medication (p=0.038), beginning of medication start (p=0.057), unemployment (p=0.059), low level of insight/education (p=0.044), male as gender (p=0.016). Conclusion: Based on the outcome of the study, we recommend the development of psycho-educational programmes on compliance and the active involvement of the relatives and significant others in the management of patients of mentally ill patients.


2019 ◽  
Vol 13 (2) ◽  
pp. 155798831983437
Author(s):  
Lesław Rusiecki ◽  
Romuald Zdrojowy ◽  
Jana Gebala ◽  
Małgorzata Sobieszczańska ◽  
Ryszard Smoliński ◽  
...  

Impairment of social functioning and low economic status may lead to the development of cardiovascular disease (CVD). This study aimed to evaluate the relationship between socioeconomic status (SES) and erectile dysfunction (ED) in patients with clinically significant CVD. A total of 808 male patients with ischemic heart disease (IHD) were recruited. Socioeconomic and demographic data as well as occupational data and the presence of modifiable risk factors were collected. Erection quality was assessed using the International Index of Erectile Function 5 (IIEF-5), while physical activity was evaluated using a modified Framingham questionnaire. Relationships among the presence of socioeconomic factors (marital status, education, income, occupational status, nature of work conducted, and demographic data), intensity of ED, and time from diagnosis of IHD were assessed. ED was diagnosed in 618 men (76.49% overall; severe in 23.14%, moderate to severe in 13.11%, moderate in 32.20%, mild in 31.55%). Patients with ED were older (61 ± 8.6 vs. 53 ± 9.1 years; p < .0001), were less active (6.97 ± 2.18 vs. 8.31 ± 2.34 Metabolic Equivalent [METs]; p < .0001), and had more modifiable risk factors (3.4 ± 1.1 vs. 3.2 ± 1.0; p < .0300). Higher education was associated with a lower probability of the occurrence of ED (OR = 0.7546; 95% CI [0.6221, 0.9153]). In patients with newly diagnosed IHD, SES correlated significantly with the presence of ED ( p = .009). Education in patients suffering from CVD has a significant relationship with both the occurrence and degree of ED. Economic status was significantly linked to the presence and degree of ED only in patients with IHD diagnosed less than 2 months before entering the study.


Author(s):  
Elisabet Sánchez-Rodríguez ◽  
Alexandra Ferreira-Valente ◽  
Filipa Pimenta ◽  
Antonella Ciaramella ◽  
Jordi Miró

Research has shown that the confinement measures implemented to curb the spread of COVID-19 can have negative effects on people’s lives at multiple levels. The objective of this cross-sectional study was to better understand the mental, physical, and socio-economic status of adults living in Spain during the late stages of the state of emergency caused by COVID-19. Five hundred and forty-four individuals responded to an online survey between 3 June and 30 July 2020. They were asked to report data about their mental and physical health, financial situation, and satisfaction with the information received about the pandemic. Means, percentages, t-test, ANOVAs, and logistic regressions were computed. A third of the participants reported symptoms of anxiety, depression, and stress, and worries about their health and the future. Participants also described mild levels of fatigue and pain during lockdown (66%), and a reduction in household income (39%). Respondents that were female, younger, single, and with lower levels of education reported experiencing a greater impact of the COVID-19 pandemic. The data showed that the negative effects of lockdown were present in the late stages of the state of emergency. The findings can be used to contribute to the development of programs to prevent or mitigate the negative impact of confinement measures.


PLoS ONE ◽  
2022 ◽  
Vol 17 (1) ◽  
pp. e0262325
Author(s):  
Nazish Imran ◽  
Fauzia Naz ◽  
Muhammad Imran Sharif ◽  
Sumbul Liaqat ◽  
Musarrat Riaz ◽  
...  

Background COVID-19 has posed unique challenges for adolescents in different dimensions of their life including education, home and social life, mental and physical health. Whether the impact is positive or negative, its significance on the overall shaping of adolescents’ lives cannot be overlooked. The aim of the present study was to explore impacts of the pandemic on the adolescents’ everyday lives in Pakistan. Methods Following ethical approval, this cross-sectional study was conducted through September to December, 2020 via an online survey on 842 adolescents with the mean age of 17.14 ± SD 1.48. Socio-demographic data and Epidemic Pandemic Impact Inventory-Adolescent Adaptation (EPII-A) was used to assess the multi-dimensional effects of the pandemic. Results Among the 842 participants, 84% were girls. Education emerged as the most negatively affected Pandemic domain (41.6–64.3%). Most of the adolescents (62.0–65.8%) had reported changes in responsibilities at home including increased time spent in helping family members. Besides, increase in workload of participants and their parents was prominent (41.8% & 47.6%). Social activities were mostly halted for approximately half (41–51%) of the participants. Increased screen time, decreased physical activity and sedentary lifestyle were reported by 52.7%, 46.3% and 40.7% respectively. 22.2–62.4% of the adolescents had a direct experience with quarantine, while 15.7% experienced death of a close friend or relative. Positive changes in their lives were endorsed by 30.5–62.4% respondents. Being male and older adolescents had significant association with negative impact across most domains (p<0.05). Conclusions Results have shown that COVID-19 exert significant multidimensional impacts on the physical, psycho-social, and home related domains of adolescents that are certainly more than what the previous researches has suggested.


2021 ◽  
Vol 10 (s1) ◽  
Author(s):  
Irma Permata Sari ◽  
S. Setyowati ◽  
Titin Ungsianik

Background: Adolescent pregnancy leads to a variety of complex problems. Adolescents with an unwanted pregnancy potentially face a stigma or rejection by parents and friends as well as facing threats to be a victim of domestic violence. Violence experienced by pregnant adolescents has a negative impact on the health status of the mother and their fetus. This study aimed to identify the factors triggering domestic violence on pregnant adolescents in Jakarta.Design and Methods: The design of the study was cross-sectional study with convenience sampling (n = 230). The tools used for data collection were questionnaires.Results: The results of the bivariate analysis showed that the factors associated with domestic violence suffered by pregnant adolescents were the partner's violence history (p=0.000), partner's behaviors (p=0.000), economic status (p=0.002) and family's support (p=0.03). The partner's behavior was the most influential factor that contributed 73.96 times the potential occurrences of domestic violence against pregnant adolescents (p=0.000; OR=73.96).Conclusions: The involvement of the partner during the pregnancy process is necessary for understanding and comprehension of the changes which may possibly occur due to the partner’s pregnancy.


2019 ◽  
Author(s):  
Seyed Mansour Gatmiri ◽  
Marjan Bordbar ◽  
Firoozeh Raisi ◽  
Anahid Nourian

There has been little attention to sexual dysfunction (SD) in women undergoing hemodialysis (HD), therefore few studies are found in this field. The aim of this study was to determine the incidence of SD, assess its association with biochemical factors, employment and educational status, economic situation, depression, anxiety, and medication. End stage renal disease (ESRD) married women aged 18 to 60 years presenting to Tehran University of Medical Sciences (TUMS) hospitals’ (Imam Khomeini, Sina, and Baharloo) from April to September 2017 were included in the study. Female Sexual Function Index (FSFI) questionnaire was used to evaluate SD. Patients were divided into two groups with SD (scores≤28) and without SD (scores˃28). Hospital Anxiety and Depression Scale (HADS) questionnaire was used to investigate anxiety and depression; patients with scores equal to or more than 11 were implied as depressed or anxious. Demographic data, duration of dialysis, ESRD causes and biochemical tests were also collected. Thirty patients (81.1%) out of 37 showed SD who were older, had lower educational and economic status, had higher hemoglobin levels and used erythropoietin products and Venofer® (iron sucrose injection) less; most of these patients were housewives. The incidence of SD among patients was high. Erythropoietin and Venofer use was less frequent in patients with SD compared to the other group. This suggests that these two products have a role in treatment of SD rather than the treatment of anemia. © 2019 Tehran University of Medical Sciences. All rights reserved. Acta Med Iran 2019;57(4):244-252.


Author(s):  
Ram K. Panika ◽  
Rakesh K. Mahore

Background: Lymphatic filariasis is a vector borne parasitic disease caused by lymphatic dwelling nematode parasite. It is one of the world's leading causes of permanent and long-term disability with an estimated 5.1 million disability adjusted life years (DALYs) are lost due to this disease. The National Health Policy 2002 aims at Elimination of Lymphatic filariasis by 2015 through Annual Mass Drug Administration (MDA) of single dose of DEC. Objective was to assess coverage and compliance of MDA Program and awareness about lymphatic filariasis in Chhatarpur district of Madhya Pradesh.Methods: Cross-sectional Study was conducted. Total 120 households were surveyed in four selected clusters of Chhatarpur district of MP.Results: Out of total 835 persons only 94.37% persons were eligible and 47 (5.62%) were not eligible for MDA for MDA. Coverage rate was 90.22% and compliance rate was 75.24%. The main reason for non-compliance was not having the concerned disease 34.38 % followed by fear of side effect (24.90%). Only 37.5% among the surveyed families were aware about MDA. Majority of respondent 21 (46.66%) acquired knowledge from health workers.Conclusions: The compliance of MDA program was low and the awareness about the lymphatic filariasis in the study population was limited in Chhatarpur district. Poor compliance of MDA is attributed to inadequate consumption of drugs due to poor awareness among eligible population. For elimination of lymphatic filariasis active involvement of community is very essential. It can be made possible through behavior change communication and health education of people.


Author(s):  
Ananta Kumar ◽  
Pracheth R.

Background: Medication adherence is regarded as a critical determinant of control of hypertension. The objective of the study was to determine the prevalence and factors associated with medication adherence among hypertensive adults, residing in a rural area of Dakshina Kannada district.Methods: A cross-sectional study was conducted from August to November 2015. A pre-designed, pre-tested proforma was used to collect information. The study participants were enquired about the medication adherence using the Morisky medication adherence scale (MMAS-8). Medication adherence was graded as high (zero score), medium (1-2 score) and low (3-8 score).Results: A total of 193 hypertensive adults fulfilling the inclusion criteria were included. Low medication adherence was observed in 56 (29.01%) of the study participants. Majority (67.88%), had medium adherence, while a very low percentage (3.11%) had high medication adherence, as per the MMAS-8. Low adherence was found to be higher among participants belonging to low socio-economic status (39.44%) when compared to other classes. This association was statistically significant (p=0.0025). Those having diabetes had higher rates of poor adherence (66.67%) when compared to non-diabetics (13.24%), which was statistically significant (p<0.0001). Consuming ≥3 medications was another factor found to be significantly associated with low medication adherence (p<0.0001).Conclusions: We conclude that 29.01% of the study participants had low medication adherence. Low socio-economic status (Class IV+V), presence of diabetes mellitus and number of medications were the factors found to be significantly associated with low medication adherence.


2016 ◽  
Vol 86 (5-6) ◽  
pp. 242-248 ◽  
Author(s):  
Genc Burazeri ◽  
Jolanda Hyska ◽  
Iris Mone ◽  
Enver Roshi

Abstract.Aim: To assess the association of breakfast skipping with overweight and obesity among children in Albania, a post-communist country in the Western Balkans, which is undergoing a long and difficult political and socioeconomic transition towards a market-oriented economy. Methods: A nationwide cross-sectional study was carried out in Albania in 2013 including a representative sample of 5810 children aged 7.0 – 9.9 years (49.5% girls aged 8.4 ± 0.6 years and 51.5% boys aged 8.5 ± 0.6 years; overall response rate: 97%). Children were measured for height and weight, and body mass index (BMI) calculated. Cut-off BMI values of the World Health Organization (WHO) and the International Obesity Task Force (IOTF) were used to define overweight and obesity in children. Demographic data were also collected. Results: Upon adjustment for age, sex, and place of residence, breakfast skipping was positively related to obesity (WHO criteria: OR = 1.5, 95% CI = 1.3–1.9; IOTF criteria: OR = 1.9, 95% CI = 1.4–2.5), but not overweight (OR = 1.1, 95% CI = 0.9–1.3 and OR = 1.1, 95% CI = 0.9–1.4, respectively). Furthermore, breakfast skipping was associated with a higher BMI (multivariable-adjusted OR = 1.05, 95% CI = 1.02–1.07). Conclusions: Our findings point to a strong and consistent positive relationship between breakfast skipping and obesity, but not overweight, among children in this transitional southeastern European population. Future studies in Albania and other transitional settings should prospectively examine the causal role of breakfast skipping in the development of overweight and obesity.


2017 ◽  
Vol 3 (2) ◽  
pp. 320-323
Author(s):  
Samar Hossain ◽  
Sharma Priyanka ◽  
Talib Hossain ◽  
Surendra Mohan Mathur

Objective: The last two decades have witnessed an increase in health care costs due to obesity and related issues among children and adolescents. Childhood obesity is a global phenomenon affecting all socio-economic groups, irrespective of age, sex or ethnicity. The study was done to find the the prevalence of obesity and overweight and their association with socioeconomic status (SES) and the risk factors. Materials and Methods: School based cross sectional study carried out over a period of 4 months in three schools of East Delhi. The study was carried out in 629 school children of 10–18 years of age and belonging to different socioeconomic statuses in schools in East Delhi. The obesity and overweight were considered using an updated body mass index reference. A pre-tested questionnaire was used to determine the Socio-economic status and life style factors. Results: The prevalence of overweight among children was higher in middle socioeconomic status groups as compared to high socioeconomic class in both boys and girls whereas the prevalence of obesity was higher in high Socio economic status group as compared to middle socioeconomic group. The prevalence of obesity as well as overweight in low SES group was the lowest as compared to other group. Conclusion: The findings of this study suggest that the prevalence of overweight and obesity varies remarkably with different socioeconomic development levels.


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