scholarly journals Role of clean intermittent self-catheterization in prevention of recurent urethral stricture after optical internal urethrotomy

2020 ◽  
Vol 1 (1) ◽  
pp. 14-17
Author(s):  
Pushupati Nath Bhatta ◽  
Akash Raya ◽  
Mohammad Shahid Alam ◽  
Rishikant Aryal ◽  
Deepak Kumar Dutta
Keyword(s):  
Urethral Stricture ◽  
Controlled Study ◽  
Control Group ◽  
Internal Urethrotomy ◽  
Medical College ◽  
National Medical ◽  
Group 2 ◽  
Optical Internal Urethrotomy ◽  
Group 1

Introduction: Urethral stricture is one of the common urological problem. There are different option to treat urethral stricture but, irrespective of the treatment the chances of recurrence is still high. Clean intermittent self-catheterization (CISC) was introduced by Lapides has greatly reduced the chances of recurrence. So, the objectives of this randomized clinical trial was to compare the chances of recurrence in optical internal urethrotomy (OIU) patients with or without CISC. Materials and methods: A randomized controlled study conducted in the department of surgery, urology division at National medical college, Birgunj from June 2019 to June 2020. Total 97 cases of age 20-80 years with stricture up to 1-2 cm were included. All cases were randomized in two groups. Group 1 (optical internal urethrotomy with clean intermittent self-catheterization) Group 2 (optical internal urethrotomy without clean intermittent self-catheterization). Results: Among total 97 cases 4 cases from group 1 and 7 cases of group 2 lost their follow-up which were excluded from the study. Total 86 patient completed the study, 43 in treatment group 1 and 43 in control group 2. Mean age of patient was 42.58±16.147 years in group 1 and 32.07±9.917 years in group 2. Majority of patient 56 (65%) were of age 20-40 years. Recurrence of stricture was seen in 9 (20.93%) cases in group 1 and 20 (46.51%) cases in group 2. Conclusions: The study concluded that clean intermittent self-catheterization is a simple and effective way of reducing the chances of recurrence after internal optical urethrotomy.

scholarly journals Effect of anterior capsular polishing on the incidence of YAG capsulotomy

2016 ◽  
Vol 11 (3) ◽  
Author(s):  
Muhammad A Ahad ◽  
Mohammad Rashad Qamar ◽  
Sameh K Hindi ◽  
Martin N Kid
Keyword(s):  
Outcome Measure ◽  
Early Postoperative Period ◽  
Controlled Study ◽  
Control Group ◽  
Anterior Capsule ◽  
Main Outcome Measure ◽  
Group I ◽  
Group 2 ◽  
One Year ◽  
Group 1

Purpose: To study the effect of anterior capsule polishing during phacoemulsification on the incidence of post operative YAG laser capsulotomy. Method: A retrospective controlled study of 159 patients who underwent uncomplicated phacoemulsification with anterior capsular polishing between October 1998 and March 2000. 169 age matched patients who underwent phacoemulsification but without anterior capsule polishing served as controls. Main outcome measure: Incidence of visually significant YAG capsulotomy, which improved the Snellen acuity for more than 1 line or at least 1 line with subjective improvements in symptoms. Results: 2.51 % of patients with anterior capsular polishing (Group 1) had YAG capsulotomy compared to 7.1% of patients in control group at one year. However, after two years, 11.3% of patients in Group I had YAG capsulotomy compared to 12.4% in Group 2. Conclusion: Anterior capsular polishing during cataract surgery may delay the opacification of posterior capsule during the early postoperative period. But does not decrease the incidence of YAG capsulotomy after two years.

scholarly journals Comprehensive rehabilitation of patients with movement disorders with spastic forms of cerebral palsy

2021 ◽  
Vol 6 (6-2) ◽  
pp. 82-91
Author(s):  
O. V. Bugun ◽  
A. V. Mashanskaya ◽  
A. V. Atalyan ◽  
V. I. Mikhnovich ◽  
T. A. Belogorova ◽  
...  
Keyword(s):  
Cerebral Palsy ◽  
Motor Skills ◽  
Exercise Therapy ◽  
Movement Disorders ◽  
Intervention Group ◽  
Controlled Study ◽  
Spastic Cerebral Palsy ◽  
Control Group ◽  
Group 2 ◽  
Group 1

Until now, there is no radical method of treating children with cerebral palsy, which allows us to consider scientific research in this direction reasonable and promising.The aim of the research: to study the effect of exercises on the mini-simulator “Kinesioplatform-swing” with biofeedback on the indicators of motor skills in children with spastic cerebral palsy.Materials and methods. We conducted an open, non-randomized, prospective, comparative, controlled study in pairs (each participant in the main group corresponds to a participant in the control group). The study involved 53 patients aged 4–12 years with cerebral palsy: the intervention group (group 1: n = 27 (13 boys, 14 girls)) and the control group (group 2: n = 26 (11 boys, 15 girls)), comparable in terms of gender, age and severity of movement disorders. Characteristics of the medical intervention: group 1 – botulinum toxin type A (BTA, for exercising against the background of relative muscular normotonus) + exercise therapy + exercises on the mini-simulator “Kinesioplatform-swing” with biofeedback (BFB); group 2 – BTA + exercise therapy. Duration of the study: 2019–2020. The difference between groups in terms of motor skills on the day of hospitalization and after completion of the training program (10 sessions each) was determined. Motor skills were assessed according to the GMFM-66/88 (Gross Motor Function Measure) table using the “Scales for measuring global motor functions”.Results. The inclusion of additional exercises on the mini-simulator “Kinesioplatformswing” with biofeedback in the rehabilitation of patients with movement disorders with spastic cerebral palsy (BTA + exercise therapy) in comparison with the control group. However, the question of the long-term effects of such training remains open and requires further study.

scholarly journals Internal urethrotomy versus plasmakinetic energy for surgical treatment of urethral stricture

2015 ◽  
Vol 87 (2) ◽  
pp. 161 ◽  
Author(s):  
Levent Ozcan ◽  
Emre Can Polat ◽  
Alper Otunctemur ◽  
Efe Onen ◽  
Oğuz Ozden Cebeci ◽  
...  
Keyword(s):  
Surgical Treatment ◽  
Urethral Stricture ◽  
Maximum Flow ◽  
Clinical History ◽  
Internal Urethrotomy ◽  
Urethral Strictures ◽  
Cold Knife ◽  
Group 2 ◽  
Stricture Recurrence ◽  
Group 1

Purpose: we aimed to compare the longterm outcome of surgical treatment of urethral stricture with the internal urethrotomy and plasmakinetic energy. Material and Methods: 60 patients, who have been operated due to urethral stricture were enrolled in our clinic. None of the patients had a medical history of urethral stricture. The urethral strictures were diagnosed by clinical history, uroflowmetry, ultrasonography and urethrography. The patients were divided two groups. Group 1 consisted of 30 patients treated with plasmakinetic urethrotomy and group 2 comprised 30 men treated with cold knife urethrotomy. Results: There were no statistically significant differences between two groups in terms of patient age, maximum flow rate (Qmax) and quality of life score (Qol) value. A statistical difference between the two groups was observed when we compared the 3rd-month uroflowmetry results. Group 1 patients had a mean postoperative Qmax value of 16,1 ± 2,3 ml/s, whereas group 2 had a mean postoperative Qmax value of 15,1 ± 2,2 ml/s (p < 0.05). In the cold knife group, 3 of 11 (27,7%) recurrences appeared within the first 3 months, whereas in the plasmakinetic group zero recurrences appeared within the first 3 months in our study. The urethral stricture recurrence rate up to the 12 month period was statistically significant for group 1 (n = 7, 23%) compared with group 2 (n = 11, 37%) (p < 0.05). Conclusion: We believe that plasmakinetic surgery is better method than the cold knife technique for the treatment of urethral stricture.

The effect of transcutaneous electrical nerve stimulation on the viability of random skin flaps in rats

2002 ◽  
Vol 10 (4) ◽  
pp. 151-154 ◽  
Author(s):  
Richard Eloin Liebano ◽  
Lydia Masako Ferreira ◽  
Miguel Sabino Neto
Keyword(s):  
Nerve Stimulation ◽  
Transcutaneous Electrical Nerve Stimulation ◽  
Skin Flap ◽  
Control Group ◽  
Skin Flaps ◽  
Electrical Nerve Stimulation ◽  
Flap Viability ◽  
Group 2 ◽  
Group 1

The aim of this study was to determine the role of transcutaneous electrical nerve stimulation (TENS) in the viability of random skin flaps. In 30 Wistar-EPM rats, a random 10×4 cm skin flap was raised and a plastic barrier was interposed between the flap and its bed. Immediately after surgery and for two subsequent days, the rats in group 1 (the control group) were anesthetized for 1 h with the electrodes positioned in the base of the flap and without the administration of the electric stimulus. The rats in group 2 (the treatment group) were submitted to TENS for 1 h immediately after the surgery and for two subsequent days. The percentage of necrotic area (averages of 43.11% in the rats in group 1 and 23.52% in the rats in group 2) was calculated on the seventh postoperative day in both groups. Statistical analysis proved that TENS was more efficient in increasing random skin flap viability than was the method used in the control group.

scholarly journals Treatment of Short Segment Anterior Urethral Stricture: Optical Internal Urethrotomy (OIU) Alone and OIU with Triamcinolone

2019 ◽  
Vol 48 (1) ◽  
pp. 31-38
Author(s):  
Mohammad Humayun Kabir Bhuiyun ◽  
Abu Masud Al Mamun ◽  
Towhid Belal ◽  
Rezawanul Haque Rabbani ◽  
Md Khairul Islam ◽  
...  
Keyword(s):  
Triamcinolone Acetonide ◽  
Urethral Stricture ◽  
Therapeutic Modality ◽  
Control Group ◽  
Internal Urethrotomy ◽  
Triamcinolone Injection ◽  
Group A ◽  
Group B ◽  
Optical Internal Urethrotomy

Optical urethrotomy has been considered standard therapy for anterior urethral stricture since its introduction in 1976. Now optical internal urethrotomy (OIU) with intralesional triamcinolone injection is a safe and effective, minimally invasive therapeutic modality. The aim of the study is to compare the outcome of OIU alone and OIU with intralesional triamcinolone injection in the treatment of anterior urethral stricture. This Quasi Experimental study was carried out among 50 male patients with bulbar urethral stricture in the Department of Urology, Dhaka Medical College Hospital, Dhaka, over a period of six months. The age range of the patients were 32-46 years and patients were divided equally into two groups, OIU with and without intralesional triamcinolone acetonide injection as Group- A (experimental group, 25 patients) and Group- B (control group, 25 patients). Post-operative evaluation was done on the basis of history and uroflowmetry. Retrograde urethrography and micturating cystourethrography were done only in patient who developed obstructive voiding problems or flow rate below 10 ml/second. Follow up was done at regular interval on 7th day, 3rd month and 6th month. Post-operative outcomes were compared between two groups. Post-operative infection was significantly higher among those OIU with intralesional Triamcinolone acetonide injection (8%) than patients without intralesional Triamcinolone acetonide injection (4%). Per operative extravasations of urine were significantly higher among those without intralesional Triamcinolone acetonide injection (4%) than subjects with intralesional Triamcinolone acetonide injection. Extravasation not influenced by steroid but this patient subsequently suffered recurrence of stricture. In Group-A, pre and post-operative Q-max were 10.25±2.21 and 22.11±2.96 ml/sec respectively. In Group-B, pre and post-operative follow up Q-max were 10.37±2.55 and 19.54±2.65 mi/sec respectively. In Group-A, pre and post-operative voiding time was 85.20±4.20 and 27.10±3.36 sec respectively. In Group-B, pre and post-operative follow up voiding time were 86.37±4.55 and 31.45±2.55 sec respectively. Post-operative recurrences of stricture were significantly higher among those without intralesional Triamcinolone acetonide injection (24%) than subjects with intralesional Triamcinolone acetonide injection (12%). Post-operative it seems that triamcinolone injection after OIU is safe method to prevent the recurrence of urethral stricture Bangladesh Med J. 2019 Jan; 48 (1): 31-38

scholarly journals PREVENTION OF POST OPERATIVE INFECTIONS IN EMERGENCY CAESAREAN SECTIONS: ROLE OF SURGICAL BUNDLE AND VAGINAL CLEANING

2021 ◽  
pp. 1-4
Author(s):  
Asma Nagori ◽  
Deeba Khanam ◽  
Shaheen Shaheen ◽  
Meher Rizvi
Keyword(s):  
Caesarean Section ◽  
Prophylactic Antibiotic ◽  
Surgical Site Infections ◽  
Infectious Complications ◽  
Medical College ◽  
Antibiotic Regime ◽  
The Difference ◽  
Group 2 ◽  
Group 1

Introduction: Caesarean section (CS) is one of the commonest surgical procedures performed in obstetrics. Postoperative infectious complications including surgical site infections (SSI) are a cause of significant morbidity after CS as compared to vaginal delivery. Aim: To assess the role of application of surgical bundle and vaginal cleaning before caesarean section in preventing postoperative infectious complications. Design: Prospective randomised interventional study. Place and duration of study: Department of Obstetrics and Gynaecology, Jawaharlal Nehru Medical College and hospital,Aligarh from November 2016 to October 2018. Methodology: Total of 216 patients undergoing emergency CS in the hospital was enrolled in the study. Patients were kept in 2 groups. In group 1, women undergoing emergency C-Section whom conventional preoperative preparation was done using savlon-povidone iodine as skin antiseptic and a 7 day postop prophylactic antibiotic regime was administered.In group 2,surgical bundle and vaginal cleaning was done but postop prophylactic antibiotic regime was reduced to 3 day Results:Overall,SSIs were most common infectious morbidity in both groups with highest incidence in group 1(14.7%) and lower in group 2(7.01%), and the difference was statistically significant. Rates of endometritis, UTI and URTI were similar among 2 groups.Duration of hospital stay was lower for group 2 (6.43+_3.29days).No Significant association was noted between haemoglobin levels <8g/dl and number of >4 vaginal examinations with risk of development of SSI (p<0.05). Conclusion:Bundled approach including vaginal cleaning has decreased the incidence of SSIs after emergency CS but larger clinical studies are needed to prove the definite role

scholarly journals A report on the clinical efficacy of a new Bougie-internal urethrectomy

2015 ◽  
Vol 9 (7-8) ◽  
pp. 447 ◽  
Author(s):  
Choe Sung Hyn ◽  
Kim Han Jong ◽  
Choe Un Chol
Keyword(s):  
Clinical Efficacy ◽  
Urethral Stricture ◽  
Endoscopic Treatment ◽  
Internal Urethrotomy ◽  
Recurrence Rates ◽  
Flow Rates ◽  
Urethral Stricture Disease ◽  
Endoscopic Urethrotomy ◽  
Group 2 ◽  
Group 1

Introduction: We compare the clinical efficacy of the new bougieinternal urethrectomy (BIU) with internal urethrotomy and urethroplasty to treat urethral stricture disease. Methods: We prospectively studied 186 people with urethral stricture disease. Of these, 84 were identified for urethroplasty and 102 for internal urethrotomy (endoscopic urethrotomy). Among the 84 identified for urethroplasty, 52 received BIU (Group 1) and the remaining 32 received urethroplasty. Among the 102 identified for internal urethrotomy, 58 received BIU (Group 2) and the remaining 44 received the internal urethrotomy. After surgery, we evaluated the clinical efficacy of the BIU (operative invasions, voiding flow rates, complications, sequelae) compared with the endoscopic treatment and urethroplasty.Results: Patient age ranged from 20 to 70 years. The follow-up period was 2 years. In the BIU Group 1, the BIU Group 2, and the internal urethrotomy (endoscopic treatment), the length of strictures were 2.9 ± 1.5, 2.8 ± 1.3, 1.6 ± 0.7, and 1.5 ± 0.6, respectively. In the BIU Group 1, the urethroplasty, the BIU Group 2, and the internal urethrotomy (endoscopic treatment), the amount of bleeding was 34.1 ± 17.1, 172.2 ± 29.8, 28.5 ± 9.8, and 49.7 ± 13.6 mL, respectively. In the BIU Group 1, the urethroplasty, the BIU Group 2, and the internal urethrotomy, the recurrence rates were 5.8%, 86%, 6.8% and 25%, and the average flow rates were 18.1 ± 4.8, 13.1 ± 3.9, 18.2 ± 3.6, 10.1 ± 3.1 mL/s, respectively. There was no sequealae (sexual dysfunction, penile change) in both BIU groups.Conclusions: The new BIU could be considered first-line treatment in all patients with indications for visual internal urethrotomy and urethroplasty.

scholarly journals The Effect of Periarticular Injection of Methylprednisolone Acetate in Patients with Primary Osteoarthritis of the Proximal Interphalangeal Joints: A Case Controlled Study

2018 ◽  
Vol 2018 ◽  
pp. 1-4 ◽  
Author(s):  
George Habib ◽  
Fahed Sakas ◽  
Suheil Artul ◽  
Fadi Khazin
Keyword(s):  
Matched Control ◽  
Controlled Study ◽  
Control Group ◽  
Methylprednisolone Acetate ◽  
Periarticular Injection ◽  
Primary Osteoarthritis ◽  
Group 2 ◽  
Approach Group ◽  
Control Study ◽  
Group 1

Backgrounds. Primary osteoarthritis of the proximal interphalangeal joints (PIPJ) is a common entity. It could be associated with local pain that has no effective treatment. Local subcutaneous periarticular injection of methylprednisolone acetate (MPA) was evaluated in a prospective case-control study. Methods. Patients with painful osteoarthritis of the PIPJ for more than 1 month not responding to nonsteroidal meds were prospectively recruited. Radiographic, demographic, clinical, and lab parameters were documented. Visual analogue scale (VAS) was documented regarding the level of PIPJ pain prior to the injection. Patients had local subcutaneous periarticular injection at the medial and lateral sides of each painful PIPJ of one hand, of 8 mg (0.2 ml) of MPA mixed with 0.1 ml of lidocaine 1% (group 1) at each side. Age- and sex-matched control group were given 0.3 ml of normal saline using the same approach (group 2) at each side. VAS was evaluated 1, 4, and 10 weeks following the injection and compared to baseline levels using Wilcoxon’s ranks signed test. Results. Eighteen and sixteen patients were recruited in group 1 and group 2, respectively. There were 11 females in group 1 with mean age of 52.7 ± 9.2 years. Mean VAS in group 1 at baseline was 67 and at weeks 1, 4, and 10 was 23 (p=0.001), 29 (p=0.001), and 55 (p=0.043), respectively. Mean VAS in group 2 at baseline was 65 and at weeks 1, 4, and 10 was 43 (p=0.005), 64 (p=0.534), and 69 (0.698), respectively. Conclusions. Subcutaneous periarticular injection of MPA + lidocaine at the PIP joints resulted in a small but significant improvement that gradually diminished with time across the week 10, among patients with primary OA of hands.

scholarly journals PATHOGENIC ROLE OF CYTOKINES IN PSORIASIS

2018 ◽  
Vol 21 (2) ◽  
pp. 90-93
Author(s):  
Sh. V Karapetyan ◽  
Khachik M. Khachikyan
Keyword(s):  
Inflammatory Cytokines ◽  
Proinflammatory Cytokines ◽  
Control Group ◽  
Moderate Severity ◽  
Duration Of Disease ◽  
Anti Inflammatory ◽  
Group 2 ◽  
Commercial Kits ◽  
Group 1

Aim. The aim of this study is determination of the role of certain pro-inflammatory and anti-inflammatory cytokines in the pathogenesis of psoriasis. Material and methods. The 110 patients with plaque form of psoriasis of moderate severity were examined, who were divided into 2 groups. Group 1 includes 65 patients (43 men and 22 women) from 18 to 64 years old with a duration of disease from 1 year to 39 years. The traditional treatment (detoxification, antioxidant, antihistamine, multivitamin, membrane stabilizing, local anti-inflammatory) was prescribed to the patients of group 1. Group 2 includes 45 patients from 18 to 65 years old (31 men and 14 women) with a duration of disease from 6 months to 32 years. The alternative treatment (with traditional therapy, the hepatoprotectors was also used) was prescribed to the patients of group 2. The control group makes 18 practically healthy periodic donors (9 men and 9 women) from 19 to 57 years old. The level of IFNγ, TNFα, IL-1α, IL-2, IL-10 and TGFβ was investigated in the serum of psoriatic patients by ELISA (commercial kits of Demeditec Diagnostics GmbH were used). Results. Before the treatment, the significant increase of level of circulating pro-inflammatory cytokines and significant decrease of level of anti-inflammatory cytokines were seen in both groups of patients with psoriasis compared with the control group. After the treatment, the level of proinflammatory cytokines is significantly reduced and the level of anti-inflammatory cytokines is significantly increased in group 1, approaching to the normal values. In group 2, the level of proinflammatory cytokines decreases more than in group 1 after the treatment. The level of anti-inflammatory cytokines also increases more than in group 1 (high treatment efficiency). The intensity of the rate of decrease of PASI after treatment in patients of group 2 is at least 1.2 times higher than in I group, of DLQI after treatment in patients of group 2 is at least 1.44 times higher than in group 1. Conclusions. The registered changes in the serum of patients with moderate severity of papular-plaque form of psoriasis indicate their essential role in the pathogenesis of psoriasis.

scholarly journals Efficiency of a new complex rehabilitation method using mechano- and kinesiotherapy for balance disorders correction in patients with osteoporotic compression vertebral fractures

2020 ◽  
Vol 97 (3) ◽  
pp. 160-166
Author(s):  
E.V. Makarova ◽  
L.A. Marchenkova ◽  
M.A. Eremushkin ◽  
E.M. Styazhkina ◽  
D.V. Razvalyaeva
Keyword(s):  
Center Of Pressure ◽  
Intervention Group ◽  
Physical Rehabilitation ◽  
Controlled Study ◽  
Vertebral Compression Fractures ◽  
Control Group ◽  
Balance Function ◽  
Group 2 ◽  
The Impact ◽  
Group 1

The aim of the study: Evaluate the impact of physical rehabilitation complex on balance function in patients with osteoporosis (OP) and vertebral compression fractures (VCFs). Materials and methods: A prospective controlled study of 40-80 years old men and women with OP and VCFs was conducted. Patients were divided into two groups by simple randomization. The intervention group (1) received an intensive rehabilitation course. The control group (2) received therapeutic exercise using the Gorinevska-Dreving method. Before rehabilitation all patients were tested: 1) stabilometry; 2) Tests: single leg stand, Fukuda test). Re-examination after rehabilitation and one month after the course. Results:The study enrolled 90 people (65.4±9.1 years). In group №1 after the course of rehabilitation there was a significant improvement in indicators: balance function coefficient (BFC) with open and closed eyes (84.1±8.6%, p=0.01 and 73.8±9.6%, p=0.01); frontal shifts (FS) (1.9 [0.7; 2,4], p=0,01), the area of statokinesiogram (ASKG) (131,9±210,4 mm2, p=0,04); center of pressure velocity (CPV) (12,2±10,1 mm/sec, p=0,001); in the Fukuda test the displacement in degrees has decreased (32.8±14.5, p=0.03), in the test «Single leg stand» the time for right and left leg with open eyes has improved (17.8±31.8 sec, p=0.001, 17.1±30.1 respectively). In group №2 there was an improvement in CPV (2.1 [1.9;5.2], p=0.001); FS movement rate (10.1±3.9 mm/sec, p=0.05). After a month in group №1 the positive dynamics by parameters was preserved: BFC with open and closed eyes, FS, CPV movement speed, SKG area, displacement in meters and degrees in the Fukuda test, standing time on the right and left legs with open and closed eyes. Conclusions: A physical rehabilitation complex aimed at training back muscles and coordination has improved balance function in patients who have experienced OP and VCFs. Pathological shift of CPV forward in frontal area was corrected and stability was improved. Stabilometry and coordination tests served as reliable methods to evaluate balance function in this group of patients.

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