scholarly journals Comprehensive rehabilitation of patients with movement disorders with spastic forms of cerebral palsy

2021 ◽  
Vol 6 (6-2) ◽  
pp. 82-91
Author(s):  
O. V. Bugun ◽  
A. V. Mashanskaya ◽  
A. V. Atalyan ◽  
V. I. Mikhnovich ◽  
T. A. Belogorova ◽  
...  
Keyword(s):  
Cerebral Palsy ◽  
Motor Skills ◽  
Exercise Therapy ◽  
Movement Disorders ◽  
Intervention Group ◽  
Controlled Study ◽  
Spastic Cerebral Palsy ◽  
Control Group ◽  
Group 2 ◽  
Group 1

Until now, there is no radical method of treating children with cerebral palsy, which allows us to consider scientific research in this direction reasonable and promising.The aim of the research: to study the effect of exercises on the mini-simulator “Kinesioplatform-swing” with biofeedback on the indicators of motor skills in children with spastic cerebral palsy.Materials and methods. We conducted an open, non-randomized, prospective, comparative, controlled study in pairs (each participant in the main group corresponds to a participant in the control group). The study involved 53 patients aged 4–12 years with cerebral palsy: the intervention group (group 1: n = 27 (13 boys, 14 girls)) and the control group (group 2: n = 26 (11 boys, 15 girls)), comparable in terms of gender, age and severity of movement disorders. Characteristics of the medical intervention: group 1 – botulinum toxin type A (BTA, for exercising against the background of relative muscular normotonus) + exercise therapy + exercises on the mini-simulator “Kinesioplatform-swing” with biofeedback (BFB); group 2 – BTA + exercise therapy. Duration of the study: 2019–2020. The difference between groups in terms of motor skills on the day of hospitalization and after completion of the training program (10 sessions each) was determined. Motor skills were assessed according to the GMFM-66/88 (Gross Motor Function Measure) table using the “Scales for measuring global motor functions”.Results. The inclusion of additional exercises on the mini-simulator “Kinesioplatformswing” with biofeedback in the rehabilitation of patients with movement disorders with spastic cerebral palsy (BTA + exercise therapy) in comparison with the control group. However, the question of the long-term effects of such training remains open and requires further study.

scholarly journals Efficiency of a new complex rehabilitation method using mechano- and kinesiotherapy for balance disorders correction in patients with osteoporotic compression vertebral fractures

2020 ◽  
Vol 97 (3) ◽  
pp. 160-166
Author(s):  
E.V. Makarova ◽  
L.A. Marchenkova ◽  
M.A. Eremushkin ◽  
E.M. Styazhkina ◽  
D.V. Razvalyaeva
Keyword(s):  
Center Of Pressure ◽  
Intervention Group ◽  
Physical Rehabilitation ◽  
Controlled Study ◽  
Vertebral Compression Fractures ◽  
Control Group ◽  
Balance Function ◽  
Group 2 ◽  
The Impact ◽  
Group 1

The aim of the study: Evaluate the impact of physical rehabilitation complex on balance function in patients with osteoporosis (OP) and vertebral compression fractures (VCFs). Materials and methods: A prospective controlled study of 40-80 years old men and women with OP and VCFs was conducted. Patients were divided into two groups by simple randomization. The intervention group (1) received an intensive rehabilitation course. The control group (2) received therapeutic exercise using the Gorinevska-Dreving method. Before rehabilitation all patients were tested: 1) stabilometry; 2) Tests: single leg stand, Fukuda test). Re-examination after rehabilitation and one month after the course. Results:The study enrolled 90 people (65.4±9.1 years). In group №1 after the course of rehabilitation there was a significant improvement in indicators: balance function coefficient (BFC) with open and closed eyes (84.1±8.6%, p=0.01 and 73.8±9.6%, p=0.01); frontal shifts (FS) (1.9 [0.7; 2,4], p=0,01), the area of statokinesiogram (ASKG) (131,9±210,4 mm2, p=0,04); center of pressure velocity (CPV) (12,2±10,1 mm/sec, p=0,001); in the Fukuda test the displacement in degrees has decreased (32.8±14.5, p=0.03), in the test «Single leg stand» the time for right and left leg with open eyes has improved (17.8±31.8 sec, p=0.001, 17.1±30.1 respectively). In group №2 there was an improvement in CPV (2.1 [1.9;5.2], p=0.001); FS movement rate (10.1±3.9 mm/sec, p=0.05). After a month in group №1 the positive dynamics by parameters was preserved: BFC with open and closed eyes, FS, CPV movement speed, SKG area, displacement in meters and degrees in the Fukuda test, standing time on the right and left legs with open and closed eyes. Conclusions: A physical rehabilitation complex aimed at training back muscles and coordination has improved balance function in patients who have experienced OP and VCFs. Pathological shift of CPV forward in frontal area was corrected and stability was improved. Stabilometry and coordination tests served as reliable methods to evaluate balance function in this group of patients.

scholarly journals Effect of anterior capsular polishing on the incidence of YAG capsulotomy

2016 ◽  
Vol 11 (3) ◽  
Author(s):  
Muhammad A Ahad ◽  
Mohammad Rashad Qamar ◽  
Sameh K Hindi ◽  
Martin N Kid
Keyword(s):  
Outcome Measure ◽  
Early Postoperative Period ◽  
Controlled Study ◽  
Control Group ◽  
Anterior Capsule ◽  
Main Outcome Measure ◽  
Group I ◽  
Group 2 ◽  
One Year ◽  
Group 1

Purpose: To study the effect of anterior capsule polishing during phacoemulsification on the incidence of post operative YAG laser capsulotomy. Method: A retrospective controlled study of 159 patients who underwent uncomplicated phacoemulsification with anterior capsular polishing between October 1998 and March 2000. 169 age matched patients who underwent phacoemulsification but without anterior capsule polishing served as controls. Main outcome measure: Incidence of visually significant YAG capsulotomy, which improved the Snellen acuity for more than 1 line or at least 1 line with subjective improvements in symptoms. Results: 2.51 % of patients with anterior capsular polishing (Group 1) had YAG capsulotomy compared to 7.1% of patients in control group at one year. However, after two years, 11.3% of patients in Group I had YAG capsulotomy compared to 12.4% in Group 2. Conclusion: Anterior capsular polishing during cataract surgery may delay the opacification of posterior capsule during the early postoperative period. But does not decrease the incidence of YAG capsulotomy after two years.

The effect of interactive computer play on balance and functional abilities in children with moderate cerebral palsy: a pilot randomized study

2019 ◽  
Vol 33 (4) ◽  
pp. 704-710 ◽  
Author(s):  
Tamis W Pin ◽  
Penelope B Butler
Keyword(s):  
Cerebral Palsy ◽  
Motor Function ◽  
Intervention Group ◽  
Controlled Study ◽  
Control Group ◽  
Gross Motor ◽  
Gross Motor Function ◽  
Gross Motor Function Measure ◽  
Significant Difference ◽  
Function Measure

Objectives: To investigate the feasibility and potential efficacy of a six-week interactive computer play training on balance and gross motor function in children with moderate cerebral palsy. Design: A pilot single-blinded matched randomized controlled study. Setting: Community. Participants: In total, 18 children with moderate cerebral palsy were recruited, paired according to age and severity of cerebral palsy and randomized into intervention group or control group. Intervention: The intervention group received additional trunk control training using the interactive computer play in sitting four times per week, 20 minutes per session for six weeks. All study children continued their usual physiotherapy programme. Measurements: All study children were assessed at baseline, week 3, week 6 (completion of intervention) and week 12 using the Pediatric Reach Test, Gross Motor Function Measure–66-Item Set and 2-Minute Walk Test. Results: All intervention children completed and enjoyed the training with no reported adverse event. All children were assessed at all time points. No significant difference was found between the two groups in all assessments. In both groups of children, significant improvements were found in the Gross Motor Function Measure–66-Item Set between week 3 (intervention group: mean 53.41, SD 5.34; control group: mean 52.86, SD 8.33) and week 6 (intervention group: mean 55.00, SD 6.32; control group: mean 54.20, SD 8.35). Conclusion: The intervention protocol of a six-week interactive computer play training was feasible and safe for children with moderate cerebral palsy in special school settings. Future studies with larger sample sizes or using single-subject designs are recommended.

scholarly journals CYP2D6 Genotype in Relation to Liver Toxicity Due to Tetrabenazine in Iraqi Patients with Hyperkinetic Movement Disorders

2020 ◽  
Vol 29 (2) ◽  
pp. 8-16
Author(s):  
Zainab A. Abbood ◽  
Shatha H. Ali ◽  
Nawfal M. Sheaheed
Keyword(s):  
Movement Disorders ◽  
Liver Enzymes ◽  
Liver Toxicity ◽  
Neurodegenerative Disorder ◽  
Enzyme Polymorphism ◽  
Controlled Study ◽  
Control Group ◽  
Cyp2d6 Genotype ◽  
The Common ◽  
Group 2

Abstract The  common types of movement disorders are ; dystonia which is a syndrome  of  repetitive muscle contractions. While , Huntington disease is autosomal dominant progressive neurodegenerative disorder, which is characterized by involuntary movements (“chorea”). Tetrabenazine therapy has been shown to effectively control this movements compared with placebo. Design the proper dosing approach for patients treated with tetrabenazine with genotype polymorphisms and their hepatic effect on patients. A prospective case controlled study was carried on 50 patients whom    divided into 2 groups :first group involved 25 patients who had chorea, and group 2 included  patients with dystonia, whom treated with (tetrabenazine) for three months. In addition to control group involved 25 healthy subjects . Blood samples were collected at the beginning and after three months  to assess  liver function  in relation to genetic polymorphism of CYP 450 2D6 enzyme for both groups and measuring the plasma concentration of tetrabenazine , alpha and beta  dyhdrotetrabenazine. The results show a significant CYP 450 2D6 enzyme polymorphism. And elevations of liver enzymes in the patient indicate hepatotoxicity of tetrabenazine and its metabolites, Determination a genotype of the CYP 450 2D6  genes in Iraqi patients, in relation  to the safety and efficacy of tetrabenazine  .

scholarly journals Potential effects of traditional massage on spasticity and gross motor function in children with spastic cerebral palsy: A randomized controlled trial

2019 ◽  
Vol 35 (5) ◽  
Author(s):  
Qamar Mahmood ◽  
Dr. Shaista Habibullah ◽  
Prof. Dr. Muhammad Naveed Babur
Keyword(s):  
Randomized Controlled Trial ◽  
Cerebral Palsy ◽  
Motor Function ◽  
Controlled Trial ◽  
Intervention Group ◽  
Spastic Cerebral Palsy ◽  
Control Group ◽  
Gross Motor ◽  
Gross Motor Function ◽  
Randomized Controlled

Objective: To evaluate the effects of traditional massage (TM) on spasticity and gross motor function in children with cerebral palsy (CP). Methods: This randomized control trial (RCT) was conducted with recruitment of 86 children (Dropped out= 11; Analyzed= 75) with spastic CP (diplegia) allocated randomly through sealed envelope method to intervention and control group with ages between 2-10 years from September 2016 to August 2018. Both groups received conventional physical therapy (CPT) once daily, five times a week for a period of three months. However, intervention group received TM additionally. Modified Ashworth Scale (MAS), Gross Motor Function Measure (GMFM-88) and Gross Motor Function Classification System (GMFCS) were used to evaluate spasticity and gross motor function at the beginning, after six and 12 weeks of intervention. Data were compared and analyzed through SPSS-20. Results: Mean age in control and intervention group was 6.81±2.31 and 7.05±2.47 years respectively. No statistically significant differences in MAS, GMFM and GMFCS scores were found at base line. The children in intervention group showed statistically significant reduction in MAS scores in all four limbs after six and 12 weeks of intervention (p < 0.05) in comparison with the control group. However, GMFM scores and GMFCS levels did not change significantly in intervention group as compared to control group. Conclusion: It is concluded that TM can effectively reduce the spasticity, does not have harmful effects, so can be administered safely by mothers at home and making it suitable for the management of spastic CP. However, in order to achieve better gross motor function, it should be practiced in conjunction with CPT, functional skills and task oriented approaches. doi: https://doi.org/10.12669/pjms.35.5.478 How to cite this:Mahmood Q, Habibullah S, Babur MN. Potential effects of traditional massage on spasticity and gross motor function in children with spastic cerebral palsy: A randomized controlled trial. Pak J Med Sci. 2019;35(5):---------. doi: https://doi.org/10.12669/pjms.35.5.478 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

scholarly journals The effects of kinesio taping of lower limbs on functional mobility, spasticity, and range of motion of children with spastic cerebral palsy

2019 ◽  
Vol 55 (1) ◽  
Author(s):  
Mirjavad Tabatabaee ◽  
Moslem Cheraghifard ◽  
Alireza Shamsoddini
Keyword(s):  
Cerebral Palsy ◽  
Range Of Motion ◽  
Muscle Tone ◽  
Intervention Group ◽  
Treatment Method ◽  
Functional Mobility ◽  
Lower Limbs ◽  
Spastic Cerebral Palsy ◽  
Control Group ◽  
Kinesio Taping

Abstract Background Cerebral palsy (CP) is a non-progressive neurological disease in a growing brain. Objective The aim of this study was to explore the effects of kinesio taping (KT) of the lower limbs on functional mobility, spasticity, and range of motion (ROM) of children with cerebral palsy. Methods Thirty children with spastic cerebral palsy aged 3 to 10 years old were selected from pediatric rehabilitation clinics. Subjects were divided randomly into intervention and control groups. Each group contains 15 subjects. Both groups received kinesio taping along with occupational therapy for 2 weeks. In the intervention group, kinesio taping was applied in a treatment mode with suitable tension; however, taping was applied in the control group in a sham mode. Timed get up and go (TUG), Modified Modified Ashworth (MMA), and goniometer tests were used prior to the intervention and 2 days and 2 weeks after the intervention. Results Short-term application of kinesio taping in the intervention group did not lead to significant changes in ROM (P = 0.582), muscle tone (P = 0.317), and functional mobility (P = 0.320). However, long-term application of kinesio taping improved the range of motion, muscle tone, and functional mobility (P < 0.05). No significant change has been observed in the control group in different intervals. Conclusion The findings indicated that kinesio taping can increase ROM of the knee and reduce spasticity. It also can improve the functional mobility. Therefore, it seems that kinesio taping is efficient for rehabilitation of spastic CP as a reliable treatment method. Trial registration IRCT, IRCT2017082135822N1, Registered 19 September 2017, https://fa.irct.ir/IRCT2017082135822N1.

scholarly journals Gaelic4Girls—The Effectiveness of a 10-Week Multicomponent Community Sports-Based Physical Activity Intervention for 8 to 12-Year-Old Girls

2020 ◽  
Vol 17 (18) ◽  
pp. 6928 ◽  
Author(s):  
Orlagh Farmer ◽  
Kevin Cahill ◽  
Wesley O’Brien
Keyword(s):  
Physical Activity ◽  
Intervention Group ◽  
Psychological Wellbeing ◽  
Control Group ◽  
Psychological Correlates ◽  
Group 3 ◽  
Group 2 ◽  
Community Sports ◽  
And Control ◽  
Group 1

Girls are less active than boys throughout childhood and adolescence, with limited research focusing on female community sports-based programs. This study aims to assess the effectiveness of a multi-component, community sports-based intervention for increasing girl’s physical activity (PA) levels, fundamental movement skill (FMS) proficiency, and psychological wellbeing, as relative to a second treatment group (the traditionally delivered national comparative program), and a third control group. One hundred and twenty female-only participants (mean age = 10.75 ± 1.44 years), aged 8 to 12 years old from three Ladies Gaelic Football (LGF) community sports clubs (rural and suburban) were allocated to one of three conditions: (1) Intervention Group 1 (n = 43) received a novel, specifically tailored, research-informed Gaelic4Girls (G4G) intervention; (2) Intervention Group 2 (n = 44) used the traditionally delivered, national G4G program, as run by the Ladies Gaelic Football (LGF) Association of Ireland; and (3) Control Group 3 (n = 33) received no G4G intervention (group 1 or 2) conditions and were expected to carry out their usual LGF community sports activities. Primary outcome measurements (at both pre- and 10-week follow up) examining the effectiveness of the G4G intervention included (1) PA, (2) FMS and (3) Psychological correlates (enjoyment levels, self-efficacy, peer and parental support). Following a two (pre to post) by three (intervention group 1, intervention group 2, and control group 3) mixed-model ANOVA, it was highlighted that intervention group 1 significantly increased in PA (p = 0.003), FMS proficiency (p = 0.005) and several psychological correlates of PA (p ≤ 0.005). The findings demonstrate that the 10-week, specifically tailored, research-informed G4G intervention is a feasible and efficacious program, leading to a positive effect on the physical and psychological wellbeing of pre-adolescent Irish girls, relative to the traditionally delivered national G4G comparative program and control group conditions.

scholarly journals The Effect of Periarticular Injection of Methylprednisolone Acetate in Patients with Primary Osteoarthritis of the Proximal Interphalangeal Joints: A Case Controlled Study

2018 ◽  
Vol 2018 ◽  
pp. 1-4 ◽  
Author(s):  
George Habib ◽  
Fahed Sakas ◽  
Suheil Artul ◽  
Fadi Khazin
Keyword(s):  
Matched Control ◽  
Controlled Study ◽  
Control Group ◽  
Methylprednisolone Acetate ◽  
Periarticular Injection ◽  
Primary Osteoarthritis ◽  
Group 2 ◽  
Approach Group ◽  
Control Study ◽  
Group 1

Backgrounds. Primary osteoarthritis of the proximal interphalangeal joints (PIPJ) is a common entity. It could be associated with local pain that has no effective treatment. Local subcutaneous periarticular injection of methylprednisolone acetate (MPA) was evaluated in a prospective case-control study. Methods. Patients with painful osteoarthritis of the PIPJ for more than 1 month not responding to nonsteroidal meds were prospectively recruited. Radiographic, demographic, clinical, and lab parameters were documented. Visual analogue scale (VAS) was documented regarding the level of PIPJ pain prior to the injection. Patients had local subcutaneous periarticular injection at the medial and lateral sides of each painful PIPJ of one hand, of 8 mg (0.2 ml) of MPA mixed with 0.1 ml of lidocaine 1% (group 1) at each side. Age- and sex-matched control group were given 0.3 ml of normal saline using the same approach (group 2) at each side. VAS was evaluated 1, 4, and 10 weeks following the injection and compared to baseline levels using Wilcoxon’s ranks signed test. Results. Eighteen and sixteen patients were recruited in group 1 and group 2, respectively. There were 11 females in group 1 with mean age of 52.7 ± 9.2 years. Mean VAS in group 1 at baseline was 67 and at weeks 1, 4, and 10 was 23 (p=0.001), 29 (p=0.001), and 55 (p=0.043), respectively. Mean VAS in group 2 at baseline was 65 and at weeks 1, 4, and 10 was 43 (p=0.005), 64 (p=0.534), and 69 (0.698), respectively. Conclusions. Subcutaneous periarticular injection of MPA + lidocaine at the PIP joints resulted in a small but significant improvement that gradually diminished with time across the week 10, among patients with primary OA of hands.

Clinical use of electrical stimulation with the Veinplicity®device and its effect on the first attempt success rate of peripheral intravenous cannulation: A non-randomized clinical trial

2019 ◽  
Vol 20 (6) ◽  
pp. 621-629 ◽  
Author(s):  
Fredericus HJ van Loon ◽  
Freek JP Willekens ◽  
Marc P Buise ◽  
Hendrikus HM Korsten ◽  
Arthur RA Bouwman ◽  
...  
Keyword(s):  
Electrical Stimulation ◽  
Success Rate ◽  
Intervention Group ◽  
Control Group ◽  
Success Rates ◽  
Moderate Risk ◽  
Intravenous Access ◽  
Group 2 ◽  
Peripheral Intravenous Access ◽  
Group 1

Background:Peripheral intravenous cannulation is one of the most frequently performed medical procedures. Venodilation, which can be achieved with different techniques, is an important factor for first attempt success. The objective of this study was to compare the first attempt success rates upon peripheral intravenous cannulation after applying a tourniquet, with venous dilation by electrical stimulation using the Veinplicity®device, or a combination of both techniques, in participants at moderate risk of a difficult peripheral intravenous access.Methods:This non-randomized clinical trial was carried out in adult patients divided into three parallel study groups, consisting of cannulation with a tourniquet (control group), cannulation after electrical stimulation without using a tourniquet (intervention group 1), and cannulation after applying electrical stimulation followed by the application of a tourniquet on the selected upper extremity (intervention group 2). The primary outcome was the first attempt success rate of peripheral intravenous catheter placement.Results:In all, 141 participants were included in this study, with an overall success rate of 86%. Success rates of 78%, 88%, and 92% were observed in the control group, intervention group 1, and intervention group 2, respectively ( p = 0.25, χ2 = 2.771, df = 2). A higher first attempt success rate was detected in participants in intervention group 2, when compared to the control group ( p = 0.04, χ2 = 4.63, df = 1).Conclusion:Increase in first attempt success was clinically relevant when electrical stimulation with the Veinplicity®device was combined with the application of a tourniquet in participants at moderate risk of a difficult peripheral intravenous access.

scholarly journals Effect of vitamin C on the incidence and severity of postdural puncture headache in patients undergoing cesarean section with spinal anesthesia

2021 ◽  
Vol 43 (1) ◽  
pp. 55-60
Author(s):  
Sepehr Eslami ◽  
Mina Shakeri
Keyword(s):  
Vitamin C ◽  
Cesarean Section ◽  
Spinal Anesthesia ◽  
Normal Saline ◽  
Intervention Group ◽  
Control Group ◽  
Significant Difference ◽  
Group 2 ◽  
Positive Effect ◽  
Group 1

Background: Some studies have shown that vitamin C has a positive effect on reducing headaches after spinal anesthesia, but studies in this field are inadequate. The aim of this study was to determine the effect of vitamin C infusion on the decrease of headache after spinal anesthesia in cesarean section. Methods: This clinical trial study was performed on 160 patients undergoing cesarean section referred to Kowsar Hospital of Yazd in 2017. The patients were randomly divided into two groups including group 1, 2 gr of vitamin C in 500 cc normal saline, and group 2, 500 cc of normal saline was injected preoperatively. The two groups were compared for headache incidence. Results: At the time of recovery, 2 hours later, the frequency of headache in the intervention group was significantly lower than the control group (P <0.05). But there was no significant difference between the two groups regarding headache at 4, 6, 12, 24, and 48 hours postoperatively (P>0.05). Conclusion: Considering the patient's condition, and according to the anesthesiologist and surgeon, vitamin C can be used to reduce pain in patients undergoing cesarean section with spinal anesthesia.

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