scholarly journals Descriptive Study Analyzing Medical and Surgical Methods of Terminating First Trimester Pregnancy

2018 ◽  
Vol 4 (1) ◽  
pp. 1-5
Author(s):  
Bhaktabatsal Raut ◽  
Shreedhar Acharya
Keyword(s):  
Failure Rate ◽  
First Trimester ◽  
Medical Sciences ◽  
Trimester Abortion ◽  
Surgical Methods ◽  
Education Status ◽  
First Trimester Of Pregnancy ◽  
One Year ◽  
Long Acting ◽  
Post Abortion

INTRODUCTION: This study was conducted to analyze the medical and surgical methods of first trimester of pregnancy. MATERIAL AND METHODS: A hospital based retrospective study done at Lumbini Zonal Hospital, Butwal over the period of one year, where all the women who had first trimester abortion services were analyzed. Age, parity, education status, failure rates and post abortion contraception were analyzed.RESULTS: There were total of 478 women who had abortion services, of which 244 women had medical method of abortion. Among them 4.89% were teenagers and 11.29% were primigravida and 6.9% were uneducated. The failure rate for medical method was 9% and for surgical method was 1.7%. Most women at their post abortion period asked for condoms, followed by DMPA, IUD and OCP as a method of contraception.CONCLUSION: Failure rate of medical method was high and acceptance of long acting post abortion contraception was low.Journal of Universal College of Medical Sciences (2016) Vol.04 No.01 Issue 13, page: 1-5

Expression of interleukin-6 (IL-6), signal transducer and activator of transcription-3 (STAT-3) and telomerase in choriocarcinomas

2020 ◽  
Vol 3 (1) ◽  
Author(s):  
Luciana Pietro ◽  
Fátima Bottcher-Luiz ◽  
Lício Augusto Velloso ◽  
Joseane Morari ◽  
Marcelo Nomura ◽  
...  
Keyword(s):  
Cell Transformation ◽  
First Trimester ◽  
Bewo Cell ◽  
Placental Development ◽  
Trimester Abortion ◽  
Bewo Cells ◽  
Culture Cells ◽  
Bewo Cell Line ◽  
Blastocyst Implantation ◽  
First Trimester Of Pregnancy

Abstract Blastocyst implantation and neoplastic invasion have some common properties related to tissue invasion, mediated by various cytokines. Aim To compare the expression of IL-6, STAT-3 and telomerase in material of abortions in the first trimester of pregnancy, at term placentas and in choriocarcinomas. Methods Immunohistochemical reactions were performed on formalin fixed and included in paraffin samples from 3 groups: abortions, normal at term placentas and choriocarcinomas. Western Blot and Real-Time PCR assays were performed on fresh material from BeWo cell line and in primary culture cells of normal placenta. Results Immunohistochemical reactions: IL-6 expression was moderate in the first trimester abortion samples and high in at term placentas and choriocarcinomas. STAT-3 was strongly positive in all groups. Telomerase expression was absent in normal at term placentas but was increased in BeWo cells. Conclusion IL-6 and STAT-3 are present in the invasion process of the normal placental development and they are maintained during the malignant transformation to choriocarcinoma. The intense telomerase expression observed in BeWo cells was strongly associated with the malignant phenotype, confirming it as a good marker for cell transformation and tumor progression.

scholarly journals Severe Neuroinflammatory Relapse After Extrauterine Pregnancy and Abortion: A Case Report on a Patient With Heterogenic Ms Phenotype Carrying Myelin Oligodendrocyte Glycoprotein Autoantibodies

2021 ◽  
Author(s):  
Katja Kulmala ◽  
Roosa Vaitiniemi ◽  
Helene Blad ◽  
Virginija Danylaite Karrenbauer
Keyword(s):  
Case Report ◽  
Pregnancy Termination ◽  
Dimethyl Fumarate ◽  
First Trimester ◽  
Myelin Oligodendrocyte Glycoprotein ◽  
Csf Biomarkers ◽  
Trimester Abortion ◽  
Disease Variant ◽  
Post Abortion ◽  
Surgical Abortion

Abstract Background. Pregnancy has disease-modifying effects in MS. First trimester abortion might be followed by increased MS activity. MS with myelin oligodendrocyte glycoprotein (MOG) autoantibodies is a rare and agressive disease variant. Objectives. This case illustrates severe inflammatory reactivation after surgical abortion in MS patient who carries MOG antibodies. Methods. Case-report. Patient provided written informed consent for information and images to be published. Results. MRI and CSF biomarkers indicated high inflammatory activity post-abortion. Conclusions. Pregnancy termination in combination with MOG antibody carriership and termination of dimethyl fumarate treatment just prior abortion have had contributed to extensive reactivation of MS.

scholarly journals P006: Management of first trimester bleeding in the emergency department

CJEM ◽  
2019 ◽  
Vol 21 (S1) ◽  
pp. S65
Author(s):  
R. Amiro ◽  
R. Clouston ◽  
J. French ◽  
P. Atkinson
Keyword(s):  
Emergency Department ◽  
Additional Data ◽  
Point Of Care ◽  
Live Birth Rate ◽  
First Trimester ◽  
Secondary Outcome ◽  
Point Of Care Ultrasound ◽  
Quality Markers ◽  
First Trimester Of Pregnancy ◽  
One Year

Introduction: Bleeding in the first trimester of pregnancy is a common presentation to the Emergency Department (ED) with half going on to miscarry. Currently there is no local consensus on key quality markers of care for such cases. Point of Care Ultrasound (PoCUS) is increasingly utilized in the ED to detect life threating pathology such as an ectopic pregnancy or fetal viability. PoCUS leads to improved patient satisfaction, quicker diagnosis and treatment. The purpose for this study was to examine the rates of formal ultrasound and PoCUS when compared to reported and recommended rates, and also to understand the use of other diagnostic tests. Methods: A retrospective cohort study of pregnant females presenting to the ED with first trimester bleeding over one year (June 2016 – June2017) was completed. A sample size of 108 patients was required to detect a moderate departure from baseline reported rates (67.8 – 77.6%). The primary outcome was the PoCUS rate in the ED. The main secondary outcome was the formal ultrasound rate. The literature recommends PoCUS in all early pregnancy bleeding in the ED, with a target of 100% of patients receiving PoCUS. Additional data recorded included the live birth rate, pelvic and speculum examination rate and lab tests. There is no clearly defined ideal practice for the additional data so these rates will be recorded without comparison. Results: Records of 168 patients were screened for inclusion. 65 cases were excluded because they were not pregnant or had confirmed miscarriage or other, leaving a total of 103 patients included in the analysis. The PoCUS rate was 51.5% (95% CI 42%-61%), lower than previously reported PoCUS rates of 73% (67.8 – 77.6%). The formal ultrasound rate was 67% (57%-75%). Both approaches were significantly lower than the recommended rate of 100% (95.7 – 100%). Rates for other key markers of care will also be presented. Conclusion: Fewer PoCUS exams were performed at our centre compared with reported and recommended rates for ultrasound. Further results will explore our current practice in the management of first trimester pregnancy complications. We plan to use this information to suggest improvements in the management of this patient population.

scholarly journals Post Abortion Choice and Acceptance of Contraception

2013 ◽  
Vol 8 (1) ◽  
pp. 14-17
Author(s):  
Ashis Shrestha ◽  
P Sharma
Keyword(s):  
Care Service ◽  
First Trimester ◽  
Contraceptive Device ◽  
Trimester Abortion ◽  
Health Care Centre ◽  
Cross Sectional ◽  
Oral Contraceptive Pills ◽  
Contraceptive Pills ◽  
Comprehensive Abortion Care ◽  
Post Abortion

Aims: This study was conducted to find out choice and acceptance of contraceptives in clients coming for first trimester abortion. Methods: This was a cross sectional descriptive study carried out from the records of clients who received comprehensive abortion care service in first trimester at Kasthamandap health care centre from June 2008 to June 2010. Results: Total 707 clients came for abortion who fulfilled inclusion criteria. Contraceptive acceptance was 49.5%. Most frequently used contraceptives were injectable (depot medroxyprogesterone) 22.8%, oral contraceptive pills 19.6%, condom 6.1%, intra-uterine contraceptive device 0.8% and norplant 0.3%. Conclusions: This study showed a low acceptance rate of contraception. This suggests the need for reviewing the policy of post abortion contraception. The study also highlighted that depot provera was the most accepted contraception. Nepal Journal of Obstetrics and Gynaecology / Vol 8 / No. 1 / Issue 15 / Jan- June, 2013 / 14-17 DOI: http://dx.doi.org/10.3126/njog.v8i1.8854

Placenta increta after first-trimester dilatation and curettage manifesting as an unusual uterine mass: magnetic resonance findings

2007 ◽  
Vol 48 (8) ◽  
pp. 938-940 ◽  
Author(s):  
W. Ju ◽  
S. C. Kim
Keyword(s):  
Magnetic Resonance ◽  
Placenta Accreta ◽  
First Trimester ◽  
Resonance Imaging ◽  
Placenta Increta ◽  
Mri Findings ◽  
Trimester Abortion ◽  
Dilatation And Curettage ◽  
First Trimester Of Pregnancy ◽  
Magnetic Resonance Imaging Mri

Placenta increta during the first trimester of pregnancy is extremely rare. Only a few cases of placenta accreta during the latter half of pregnancy manifesting as a uterine mass have been published. This report describes a case of placenta increta that caused prolonged bleeding after a first-trimester abortion, and was identified by magnetic resonance imaging (MRI) as a heterogeneous mass in the myometrium. This is the first report of a placenta increta detected as a uterine mass after first-trimester dilatation and curettage, and its MRI findings.

‘STUDY OF LONG ACTING REVERSIBLE CONTRACEPTION(LARC) AFTER ABORTION'

2021 ◽  
pp. 12-14
Author(s):  
Shreya P Aaglawe ◽  
Sonali Deshpande ◽  
Shrinivas Gadappa ◽  
Swati Badgire ◽  
Pooja Phadtare ◽  
...  
Keyword(s):  
Single Case ◽  
Uterine Perforation ◽  
Contraceptive Device ◽  
Minimal Risk ◽  
Complication Rates ◽  
Continuation Rate ◽  
Expulsion Rate ◽  
Trimester Abortion ◽  
Long Acting ◽  
Post Abortion

Background: The study was conducted to evaluate clinical outcome of post abortion intrauterine contraceptive device (PAIUCD) insertion in terms of acceptability, complications, expulsion and continuation rate. Methods: A prospective observational study was conducted in GMCH, Aurangabad from 2018 to 2020 after Institution Ethics committee approval. Results:Total 250 women were recruited in study. Acceptance rate of PAIUCD was 13.13%. Their age ranges from 20-36years.Majority of women who underwent PAIUCD insertion (77.3%) were from lower middle socioeconomic class of Modied Kuppuswami scale. Around 54.8% were primiparas. Complication rates of immediate PAIUCD insertion were low. Not a single case of uterine perforation was noted. The complications associated with PAIUCD were heavy menstrual bleeding (7.94%), irregular bleeding (4.2%), dysmenorrhea (6.5%) and pelvic infection (1.4%). Expulsion rate was 7.47%. It was found to be higher (5.53%) in cases of mid trimester abortion than in cases of rst trimester abortion (1.87%). Continuation rate was78.97% at the end of 6 months. Conclusion: Higher rate of continuation with lower rate of expulsion, pelvic inammatory disease and minimal risk of perforation were noted after PAIUCD insertion. PAIUCD was safe and well tolerated by women.

scholarly journals DISTURBANCE OF THE PROGESTERONE AND ITS METABOLITES SYNTHESIS IN THE DEVELOPMENT OF NEUROLOGICAL DISORDERS IN CHILDREN AFTER CYTOMEGALOVIRUS INFECTION DURING PREGNANCY

2018 ◽  
Vol 3 (4) ◽  
pp. 78-84
Author(s):  
I. V. Dovzhikova ◽  
I. A. Andrievskaya ◽  
N. A. Ishutina ◽  
I. N. Gorikov ◽  
S. V. Medvedeva ◽  
...  
Keyword(s):  
Pregnant Women ◽  
Neurological Disorders ◽  
First Trimester ◽  
Neurological Dysfunction ◽  
Viral Agent ◽  
Cmv Infection ◽  
First Trimester Of Pregnancy ◽  
Latent Disease ◽  
One Year ◽  
The Impact

Cytomegalovirus (CMV) infection is one of the causes of congenital neurological disorders and the virus itself is the most common viral  agent causing an imbalance in the production of placenta  progesterone and its neuroactive metabolites – allopregnenolone and 5α-dihydroprogesterone. The aim was to evaluate the concentration  of progesterone and its metabolites – 5α-dihydroprogesterone and  allopregnenolone – in placenta during exacerbation of CMV infection  in the first trimester of pregnancy, and the impact of these  disturbances on the development of neurological disorders in children. We examined 30 pregnant women with exacerbation of  CMV infection in the first trimester of pregnancy and 30 pregnant  women with latent disease; and later their newborns. The enzyme  immunoassay was used to determine  concentration of progesterone  in placenta; the histochemical method – to determine 5α-dihydroprogesterone and allopregnenolone. Newborns underwent  neurosonography studies. Exacerbation of CMV infection in the first  trimester of pregnancy decreased progesterone in placenta by 1.3  times, 5α-dihydroprogesterone – by 1.73 times and allopregnenolone – by 2 times. Ultrasound examination of the brain  showed ventriculomegaly, periventricular ischemia, and pseudocysts  in newborns up to one year from mothers with exacerbation of CMV  during pregnancy. Later, minimal brain dysfunctions were manifested by motor disorders, increased general, vegetative excitability, and a  tendency to digestive and sleep disorders. The data obtained  indicate that the exacerbation of CMV infection in the first trimester  of pregnancy is interrelated with a decrease in the concentration of progesterone and its metabolites (5α-dihydroprogesterone, allopregnenolone) in the placenta and development of neurological dysfunction in newborns.

scholarly journals First trimester bleeding and pregnancy outcome

2017 ◽  
Vol 6 (4) ◽  
pp. 1484
Author(s):  
Pradnya Digambar Kamble ◽  
Amarjeetkaur Bava ◽  
Mansi Shukla ◽  
Y. S. Nandanvar
Keyword(s):  
Vaginal Bleeding ◽  
Tertiary Care ◽  
First Trimester ◽  
Care Hospital ◽  
Premature Rupture Of Membranes ◽  
Premature Rupture ◽  
Trimester Abortion ◽  
Uterine Growth ◽  
Fetal Complications ◽  
One Year

Background: The outcome of first trimester vaginal bleeding is a matter of debate. This study sought to determine the maternal and perinatal outcome in patients presenting with first trimester vaginal bleeding.Methods: This prospective observational study was done on 1007 women with first trimester vaginal bleeding at a tertiary care hospital in Mumbai over a period of one year. A detailed history was taken and USG was done to confirm diagnosis. All these patients were evaluated for the outcomes including  threatened abortions, spontaneous, complete or incomplete abortions, sub-chorionic hematoma, Intra-uterine Fetal Demise, missed abortions, second and third trimester bleeding, Intra-uterine Growth Restriction, premature rupture of membranes and preterm deliveries.Results: Out of the 11835 confinements 1007 patients presented with first trimester vaginal bleeding. The incidence was highest (52.3%) in the age group of 21-30 years. 63.9% primigravidas presented with first trimester bleeding as compared to 36.1% of multigravidas.  It was seen that 76.9% patients who presented before 6 weeks aborted whereas only 7% patients who presented after 10 weeks aborted. Out of the 163 patients that continued pregnancy after first trimester vaginal bleeding 1.8% had a second trimester abortion, 15.3% went into preterm labour 6.75% has premature rupture of membranes and 1.8% had antepartum hemorrhage.Conclusions: According to the results of present study, first trimester vaginal bleeding predicts auxiliary maternal and fetal complications. Also, as the clinical intermediation has an important role in continuance of pregnancy and in reducing the fetal complications precise management and planning by physician is important.

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