scholarly journals Effect of Early Childhood Malnutrition on Tooth Eruption Sequence in Nepalese Children

2020 ◽  
Vol 35 (2) ◽  
pp. 22-33
Author(s):  
Nameeta Shrestha ◽  
J. Acharya
Keyword(s):  
Early Childhood ◽  
Tooth Eruption ◽  
Chronic Illnesses ◽  
Caries Experience ◽  
Healthy Children ◽  
Childhood Malnutrition ◽  
Under Nutrition ◽  
Malnourished Children ◽  
Decayed Tooth ◽  
Delayed Eruption

Child under-nutrition has effects which last a lifetime. The consequences can be both short term and long term. Malnourished children tend to be physically, emotionally and intellectually less productive and suffer more from chronic illnesses and disabilities compared to healthy children. The objective of this study was to determine prevalence of under-nutrition and investigate association between early childhood malnutrition and deciduous tooth eruption in children aged 0-59 months in Mugu district of Nepal. A structured questionnaire based on Nepal Demographic and Health Survey 2011 questionnaire was used. Weight and height of 246 children, aged 0-59 months were measured. Dental caries status and eruption sequence were noted. Among the total, 14 .1% had moderate/severe wasting of muscles, 25.2% were moderately stunted and 36.6% were severely stunted. From the total, 30 .5% were moderately underweight and 18.3% were severely underweight. A significantly higher proportion with wasting presented with delayed eruption sequence than those without wasting (p <0.05). From the total, 25.4% who presented with delayed eruption also had at least one decayed tooth (p><0.05). From this study, it was concluded that malnutrition causes delayed tooth eruption, affects the oral health of the child, and results in an increased caries experience.

Thyroid Function during Early Life and Dental Development

2017 ◽  
Vol 96 (9) ◽  
pp. 1020-1026 ◽  
Author(s):  
S. Vucic ◽  
T.I.M. Korevaar ◽  
B. Dhamo ◽  
V.W.V. Jaddoe ◽  
R.P. Peeters ◽  
...  
Keyword(s):  
Early Childhood ◽  
Cord Blood ◽  
Thyroid Function ◽  
Tooth Eruption ◽  
Open Bite ◽  
Dental Development ◽  
Healthy Children ◽  
Inverse Association ◽  
Dental Tissues ◽  
Maternal Thyroid

Children with low levels of thyroid hormones (hypothyroidism) have delayed tooth eruption, enamel hypoplasia, micrognathia, and anterior open bite, whereas children with hyperthyroidism may suffer from accelerated tooth eruption, maxillary, and mandibular osteoporosis. However, it is still unknown whether thyroid function variations within the normal or subclinical range also have an impact on hard dental tissues in healthy children. The objective of this study was, therefore, to investigate the association between thyroid function from the fetal period until early childhood and dental development at school age. This study is embedded in the Generation R Study, a population-based cohort study established in Rotterdam, the Netherlands. Maternal thyroid function (thyroid-stimulating hormone [TSH], free thyroxine [FT4], and thyroid peroxidase antibody [TPOAb] concentrations) was measured during early pregnancy, and thyroid function of the offspring (TSH and FT4) was measured in cord blood at birth and in early childhood (6 y). Dental development was assessed from panoramic radiographs of children of school-going age (9 y). In total, 2,387 to 2,706 subjects were available for the multivariable linear regression analysis, depending on the point in time of thyroid function measurement. There was an inverse association between cord blood and early childhood TSH concentrations with dental development, with a –0.06 lower standard deviation (SD) per 1 mU/L of TSH (95% confidence interval [CI], –0.11 to –0.01) and a –0.06 lower SD per 1 mU/L of TSH (95% CI, –0.11 to 0.00), respectively. There was no association between the maternal thyroid function during pregnancy and the dental development score of the child. However, TPOAb-positive mothers had children with a –0.20 SD (adjusted 95% CI, –0.35 to –0.04) lower dental development score compared with TPOAb-negative mothers. The findings of this study suggest that the thyroid hormone is involved in the maturation of teeth from the early stages of life onward.

Effect of early childhood malnutrition on tooth eruption in Haitian adolescents

2008 ◽  
Vol 36 (2) ◽  
pp. 179-189 ◽  
Author(s):  
W. Psoter ◽  
B. Gebrian ◽  
S. Prophete ◽  
B. Reid ◽  
R. Katz
Keyword(s):  
Early Childhood ◽  
Tooth Eruption ◽  
Childhood Malnutrition ◽  
Haitian Adolescents

scholarly journals Prevalence and severity of early childhood caries in malnourished children in Mendoza, Argentina

2020 ◽  
Vol 33 (3) ◽  
pp. 209-215
Author(s):  
Claudia Fernández ◽  
María Borjas ◽  
Salvador Cambría-Ronda ◽  
Walther Zavala
Keyword(s):  
Early Childhood ◽  
Early Childhood Caries ◽  
Cross Sectional Study ◽  
Dental Status ◽  
Early Years ◽  
Caries Experience ◽  
Cross Sectional ◽  
Malnourished Children ◽  
Icdas Ii ◽  
Childhood Caries

The aim of this correlational, descriptive, cross-sectional study was to describe the pathological profile of Early Childhood Caries (ECC) in malnourished children who attended two centers for prevention and treatment of child malnutrition in Mendoza, Argentina. The study included 145 children aged 12 to 71 months, with prior parental consent, and recorded dmft and dmfs according to ICDAS II 2 to 6 and 4 to 6 active caries categories, age and severity of caries experience. Parametric and non-parametric statistics were applied with p=0.05. Caries prevalence for enamel and dentin lesions was 48.2%, declining to 35.2% when only dentin lesions were considered (dmft 4-6). The following means were found for dmft and dmfs: dmft 2-6 2.10 ± 3.31, with “d” 2.03 ± 3.24; dmfs 3.07 ± 6.1 with “d” 2.91 ± 6.1; dmft 4-6 1.21 ± 2.46 with “d” 1.14 ± 2.37; dmfs 4-6 1.98 ± 5.14 and “d” 1.86 ± 5.06. There were statistically significant differences between dmft 2-6 and dmft 4-6. Active enamel lesions (ICDAS II active categories 2 and 3) accounted for 37% of total lesions. Active lesions type 5 were the most frequent. The indicators for dental status and severity of caries experience increased with age, both with moderate positive correlations. Conclusions: Malnourished children under six years old studied in Mendoza presented comorbidity with ECC. Dental status worsened with age. The values for caries indicators demonstrated the weight of caries diagnoses in early stages and the importance of providing preventive measures and systematic monitoring during these children’s early years of life.

scholarly journals Changes in epigenetic profiles throughout early childhood and their relationship to the response to pneumococcal vaccination

2021 ◽  
Vol 13 (1) ◽  
Author(s):  
Sara Pischedda ◽  
Daniel O’Connor ◽  
Benjamin P. Fairfax ◽  
Antonio Salas ◽  
Federico Martinon-Torres ◽  
...  
Keyword(s):  
Early Childhood ◽  
Immune System ◽  
T Cell Activation ◽  
Specific Antibody ◽  
Cell Activation ◽  
Pneumococcal Vaccination ◽  
Antibody Responses ◽  
Healthy Children ◽  
Epigenetic Changes ◽  
Pneumococcal Infections

Abstract Background Pneumococcal infections are a major cause of morbidity and mortality in young children and immaturity of the immune system partly underlies poor vaccine responses seen in the young. Emerging evidence suggests a key role for epigenetics in the maturation and regulation of the immune system in health and disease. The study aimed to investigate epigenetic changes in early life and to understand the relationship between the epigenome and antigen-specific antibody responses to pneumococcal vaccination. Methods The epigenetic profiles from 24 healthy children were analyzed at 12 months prior to a booster dose of the 13-valent pneumococcal conjugate vaccine (PCV-13), and at 24 months of age, using the Illumina Methylation 450 K assay and assessed for differences over time and between high and low vaccine responders. Results Our analysis revealed 721 significantly differentially methylated positions between 12 and 24 months (FDR < 0.01), with significant enrichment in pathways involved in the regulation of cell–cell adhesion and T cell activation. Comparing high and low vaccine responders, we identified differentially methylated CpG sites (P value < 0.01) associated with HLA-DPB1 and IL6. Conclusion These data imply that epigenetic changes that occur during early childhood may be associated with antigen-specific antibody responses to pneumococcal vaccines.

Dental Caries Severity and Nutritional Status of Nigerian Preschool Children

2021 ◽  
pp. 238008442110021
Author(s):  
O.O. Olatosi ◽  
A.A. Alade ◽  
T. Naicker ◽  
T. Busch ◽  
A. Oyapero ◽  
...  
Keyword(s):  
Early Childhood ◽  
Dental Caries ◽  
Nutritional Status ◽  
Early Childhood Caries ◽  
Z Score ◽  
Cross Sectional ◽  
Risk Of Death ◽  
Malnourished Children ◽  
Z Scores ◽  
Childhood Caries

Introduction: Malnutrition in children is one of the most prevalent global health challenges, and malnourished children have a higher risk of death from childhood diseases. Early childhood caries (ECC) is the most common chronic disease of childhood. Complications from ECC such as pain, loss of tooth/teeth, and infection can undermine a child’s nutrition and growth. Aim: This study aims to evaluate the severity of decay, missing, and filled tooth (dmft) by nutritional status using the z scores of the anthropometric measurements: height for age (HFA), weight for age (WFA), weight for height (WFH), and body mass index for age (BMIA) among children with ECC in Nigeria. Study Design: This is a cross-sectional study conducted in 5 local government areas (LGAs) in Lagos State, Nigeria. A multistage sampling technique was used. Results: A total of 273 cases of ECC were included in the analyses (mean age 4.19 ± 0.96 y). Overall, the mean dmft was 3.04 ± 2.28, and most (96%) were accounted for by untreated decay. The distribution of dmft within the different z score categories of BMIA (<–3 = severely wasted, –2 to –3 = wasted, –2 to +2 = normal, +2 to +3 = overweight and >+3 = obese) showed the highest dmft scores among the combined severely wasted and wasted groups, lowest among children with normal z scores, and intermediate in the overweight and obese groups. There was a significant negative correlation between BMIA z score, WFH z score, and dmft ( r = −0.181, P < 0.05 and r = −0.143, P < 0.05, respectively). However, the correlations between HFA z score, WFA z score, and dmft were positive but not significant ( r = 0.048, P = 0.44 and r = 0.022, P = 0.77, respectively). Conclusion: Our study showed an increased severity of dental caries among severely wasted or wasted children with ECC compared to those of normal or overweight. Knowledge Transfer Statement: The results from this study will raise awareness among clinicians and policy makers on the need for a primary prevention program for early childhood caries in countries with high burden of malnutrition and limited resources. Also, it will help draw the attention of clinicians to the caries status of malnourished children that can be managed to improve the nutritional outcomes.

Streptococcus Mutans Strains in Mother-Child Pairs of Children with Early Childhood Caries

2019 ◽  
Vol 43 (4) ◽  
pp. 252-256 ◽  
Author(s):  
Priya Subramaniam ◽  
Revathy Suresh
Keyword(s):  
Early Childhood ◽  
Dental Caries ◽  
Streptococcus Mutans ◽  
Early Childhood Caries ◽  
Mutans Streptococci ◽  
Similar Distribution ◽  
Healthy Children ◽  
Only Children ◽  
Polymerase Chain ◽  
Childhood Caries

Objective: Dental caries is both an infectious and transmissible disease. Maternal transfer of Mutans Streptococci occurs at an early age and is important in the initiation of dental caries in children. The aim of this study was to identify certain strains of Streptococcus mutans in mother-child pairs, of children with early childhood caries. Study design: Sixty mother-child pairs of healthy children aged 18–36 months were selected. Mothers with high levels of Streptococcus mutans in their saliva and only children with ECC were included. Dental plaque samples were collected from mother-child pairs. The plaque samples were stored, transferred to the laboratory and analyzed for Streptococcus mutans strains c, f, e and k, present in mother-child pairs using Real time Polymerase Chain Reaction (PCR) technique. Data obtained was subjected to statistical analysis for level of similarity in Streptococcus mutans strains present in mother-child pairs. Results: A similar distribution of Streptococcus mutans strains c, f and k was identified in 28 mother-child pairs. Streptococcus mutans strain e was seen in 18 pairs. Conclusion: Less than 50% of mother-child pairs showed similarity in distribution of Streptococcus mutans strains.

scholarly journals Association of Feeding Methods and Streptococcus mutans Count with Early Childhood Caries: A Cross-sectional Study

2017 ◽  
Vol 10 (2) ◽  
pp. 119-125 ◽  
Author(s):  
Manjunath P Puranik ◽  
Deepa Bullappa ◽  
KR Sowmya ◽  
T Nagarathnamma
Keyword(s):  
Early Childhood ◽  
Streptococcus Mutans ◽  
Early Childhood Caries ◽  
Cross Sectional Study ◽  
Caries Experience ◽  
Sectional Study ◽  
Cross Sectional ◽  
Mothers And Children ◽  
Feeding Methods ◽  
Childhood Caries

ABSTRACT Introduction Early childhood caries (ECC) is a virulent form of dental caries that can destroy the primary dentition of toddlers and preschool children. The aim was to determine the relationship of feeding methods and oral Streptococcus mutans count in 3- to 5-year-old children with ECC. Materials and methods A cross-sectional study was conducted in children aged 3 to 5 years. Participating mothers were interviewed regarding child's demographic profile, educational level and socioeconomic status of parents, past medical and dental history of the mother and child, child's feeding habits, and dietary habits and oral hygiene practices of mother and child. Clinical examination for dental caries was done using the World Health Organization criteria (1997). Salivary samples of mother–child pair were collected to determine the pH, flow rate, and S. mutans count. Statistical tests, such as Student's t-test, analysis of variance, and Pearson's correlation were applied. Results Out of 150 mother–child pair, statistically significant difference in the caries experience was found between mothers and children with high and low S. mutans count. Moderate but statistically significant negative correlation was found between mean decayed, missing, and filled teeth of mothers and mean decayed, extracted and filled teeth (deft) of children with high S. mutans count. Regarding deft, there was no statistically significant difference between children who were exclusively breast fed (7.85 ± 2.94), exclusively bottle-fed (8.67 ± 3.98), and both breast and bottle-fed (7.77 ± 2.91). Conclusion The mean caries experience of mothers and children was 2.66 ± 2.01 and 7.82 ± 2.94 respectively, with decayed component being maximum. Moderate and significant correlation (r = 0.5) was found between S. mutans of mothers and children in saliva. Significant negative correlation was found between mothers and children with high S. mutans count (r = –0.0284; p = 0.046). How to cite this article Bullappa D, Puranik MP, Sowmya KR, Nagarathnamma T. Association of Feeding Methods and Streptococcus mutans Count with Early Childhood Caries: A Cross-sectional Study. Int J Clin Pediatr Dent 2017;10(2):119-125.

scholarly journals Prevalence of Dental Caries Among Costa Rican Male Students Aged 12-22 Years Using ICDAS-II

2021 ◽  
pp. 378-392
Author(s):  
Sylvia Gudiño-Fernández ◽  
Adrián Gómez-Fernández ◽  
Katherine Molina-Chaves ◽  
Juan Barahona-Cubillo ◽  
Romain Fantin ◽  
...  
Keyword(s):  
Public Health ◽  
Dental Caries ◽  
Young People ◽  
Costa Rican ◽  
Assessment System ◽  
Male Students ◽  
Caries Experience ◽  
Dental Decay ◽  
Icdas Ii ◽  
Decayed Tooth

Objective: Dental decay is a public health challenge in Low- and Middle-Income Countries, particularly for young people, often confronted to healthcare access barriers. The aim of this study was to determine the prevalence and severity of dental caries among young male students in Costa Rica. Study design: A cross-sectional study was performed in 428 Costa Rican male students aged 12-22 years, who attended a nonprofit social welfare boarding school in 2019. A clinical examination was ran by three calibrated examiners following the International Caries Detection and Assessment System (ICDAS-II). Results: Caries prevalence was estimated at 83%, 15% have lost a tooth due to dental decay, 61% have at least one filled tooth, 36% have at least one filled and decayed tooth. The most frequent caries lesions were codes 2-Inactive (46.7%), and code 1-Inactive (23.8%). DMFT indicated a mean index using ICDAS-II 1-6>0 codes of 7.89. Using ICDAS-II 3-6>0 as threshold, the index decreases to 3.94. Finally, the lower and upper first permanent molars were found to be the most affected teeth. Conclusions: Dental caries experience represents a significant public health burden in young people, requiring better access to public dental healthcare.

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