scholarly journals Features of total and longitudinal body sizes in men with benign nevi

2021 ◽  
Vol 27 (3) ◽  
pp. 61-66
Author(s):  
Yousif Haddad Nabil Basim ◽  
О.А. Serebrennikova ◽  
I.V. Gunas ◽  
Yu.V. Kyrychenko ◽  
T.O. Rekun
Keyword(s):  
Statistical Processing ◽  
Lower Extremities ◽  
Data Bank ◽  
The Body ◽  
Healthy Men ◽  
Melanocytic Nevi ◽  
Dysplastic Nevi ◽  
Body Sizes ◽  
Indispensable Tool ◽  
Benign Nevi

The use of anthropometric markers to predict the onset or severity of the disease is key to solving the problem of preventive medicine and can be an indispensable tool in preventive examinations in schools, universities and industries. The purpose of the study was to establish total and longitudinal body sizes in men of the first mature age with benign nevi. Anthropometry (determination of total and longitudinal body sizes) was performed according to Bunak’s scheme for men (aged 22-35 years) patients with melanocytic benign simple nevi (n=34), melanocytic benign dysplastic nevi (n=27), melanocytic benign congenital nevi (n=14) and non-melanocytic benign nevi (n=17). As a control from the data bank of the research center of National Pirogov Memorial Medical University, Vinnytsya selected total and longitudinal body sizes of 82 practically healthy men of the same age group. Statistical processing of the obtained results was performed in the license package “Statistica 5.5” using non-parametric evaluation methods. It was found that the mass and surface area of the body in healthy men is lower than in patients (except for dysplastic nevi), and in patients with dysplastic nevi – lower than in patients with non-melanocytic nevi; the height of the suprathoracic, acromial and finger anthropometric points in healthy men is lower than in patients with nevi (except for the acromial point height in patients with dysplastic nevi), and the height of the pubic and acetabular anthropometric points – in healthy men is greater than in patients with simple (only pubic point) and dysplastic nevi; in addition, the height of the pubic and acetabular anthropometric points in patients with simple nevi is lower than in patients with non-melanocytic nevi and congenital nevi (only for the acetabulum height). Given the height of anthropometric points and the fact that body length between healthy and sick men has no significant or tendency differences, in sick men we observe a longer torso and shorter lower extremities (most pronounced in patients with simple and dysplastic nevi), which is a manifestation of “subpathological” constitutional types, which indicate a longer torso and shorter lower extremities.

scholarly journals Features of skinfold thickness in men with benign nevi

2021 ◽  
Vol 27 (4) ◽  
pp. 59-64
Author(s):  
Yousif Haddad Nabil Basim
Keyword(s):  
Statistical Processing ◽  
Data Bank ◽  
Skinfold Thickness ◽  
The Body ◽  
Control Group ◽  
Healthy Men ◽  
Adult Age ◽  
Dysplastic Nevi ◽  
Medical University ◽  
Benign Nevi

Nevi, although benign neoplasms of the skin, but have a certain tendency to malignancy, which is influenced by various external and internal human factors. Predicting the risk of benign nevi against this background is an important topic for experimental research. The aim of the study was to establish the features of the skinfold thickness (SFT) in men of the first adult age with benign nevi. SFT was determined according to the Bunak scheme for men (aged 22-35 years) with melanocyte benign simple nevi (n=34), melanocyte benign dysplastic nevi (n=27), melanocyte benign congenital nevi (n=14) and non-melanocyte benign (n=17). The control group – SFT of 82 practically healthy men of the same age group was selected from the data bank of the Research Center of National Pirogov Memorial Medical University, Vinnytsya. Statistical processing of the results was performed in the license package “Statistica 5.5” using non-parametric evaluation methods. It was found that in practically healthy men higher than in patients – SFT on the anterior and posterior surfaces of the shoulder and thigh (in all groups of patients); SFT on the forearm, at the lower angle of the scapula, chest and shin (only in patients with melanocyte benign dysplastic nevi). Also in healthy men are found lower than in patients – SFT on the side (in all groups of patients); SFT in the abdomen (in patients with melanocyte benign simple and non-melanocyte benign nevi). When comparing SFT between patients with benign nevi, in most cases, lower values of SFT found in patients with melanocyte benign dysplastic nevi. The obtained results indicate the initial manifestations of abdominal (android) type of fat deposition in the body in patients with benign nevi (most pronounced in patients with melanocyte benign simple nevi).

scholarly journals Total, longitudinal and transverse body sizes in men with psoriasis of different somatotypes

2021 ◽  
Vol 27 (4) ◽  
pp. 35-40
Author(s):  
Al-Qaraleh Obadeh Bassam Abdel-Rahman ◽  
О.Ye. Maievskyi ◽  
А.А. Glushak ◽  
І.V. Olkhova ◽  
H.V. Chaika
Keyword(s):  
Lifestyle Modification ◽  
Severe Disease ◽  
Statistical Processing ◽  
Risk Groups ◽  
Data Bank ◽  
Severe Psoriasis ◽  
The Body ◽  
Body Structure ◽  
Healthy Men ◽  
Body Sizes

Using a constitutional approach to predict the onset of a disease can be key not only to solving the problem of late-stage lifestyle modification therapy but also to understanding the deep, seemingly incomprehensible links between organs and body structure. The aim of the study was to establish and analyze the differences in total, longitudinal and transverse body sizes between healthy and/or psoriatic men of different somatotypes depending on the severity of the disease. Anthropo-somatotypological examination was performed on Ukrainian men (aged 22 to 35 years) with psoriasis (n=100, including 32 with mild and 68 with severe). A clinical assessment of the severity and area of psoriatic lesions was performed using the PASI index. Anthropometric data of 82 practically healthy men of the same age group was taken from the data bank of the research center of National Pirogov Memorial Medical University, Vinnytsya. Statistical processing of the obtained results was performed in the license package “Statistica 5.5” using non-parametric evaluation methods. In patients with mild and severe psoriasis, men of mesomorphic and endo-mesomorphic somatotypes in comparison with healthy men of the corresponding somatotypes, higher values of almost all total (in the endo-mesomorphs with severe disease), transverse (except for shoulder width) and lateral body size (except endo-mesomorphs with severe disease) was found. In patients with psoriasis, men of endo-mesomorphic somatotype with a mild course of the disease found greater than in patients with a similar course men of mesomorphic somatotype, body weight, length and surface area, height of acromial and finger anthropometric points, and transverse middle thoracic diameters and anteroposterior middle thoracic diameter; and in patients with psoriasis men of endo-mesomorphic somatotype with a severe course of the disease – only greater values than in patients with a similar course of the disease men of mesomorphic somatotype, interspinous distance. When comparing the total, longitudinal and transverse dimensions of the body between men with psoriasis of the corresponding somatotypes, in representatives of the mesomorphic somatotype with a mild course of the disease found greater than with severe course, body length values and lower – posterior middle thoracic diameter. The revealed differences in total, longitudinal and transverse body sizes between healthy and/or patients with mild or severe psoriasis Ukrainian men of mesomorphic and endo-mesomorphic somatotypes provide an opportunity to increase the effectiveness of the use of body structure and size to identify risk groups psoriasis.

Girth body dimensions in men and women with seborrheic dermatitis of varying severity

2021 ◽  
Vol 27 (4) ◽  
pp. 22-27
Author(s):  
Ahmad Raed Khasawneh ◽  
I.V. Serheta ◽  
N.V. Belik ◽  
A.O. Dovhan ◽  
I.I. Zhuchenko
Keyword(s):  
Body Size ◽  
Seborrheic Dermatitis ◽  
Severe Disease ◽  
Statistical Processing ◽  
Modern Medicine ◽  
The Body ◽  
Control Group ◽  
Men And Women ◽  
Healthy Men ◽  
Body Sizes

Today in modern medicine the study of human health is reoriented to the individual principle, which is based on the identification and study of constitutionally determined patterns of manifestation of certain diseases. The purpose of the study is to establish and analyze the features of the girth body sizes in men and women with generalized fatty form of seborrheic dermatitis of varying severity. The comprehensive body size of 40 men and 40 young women (25-44 years) with generalized fatty seborrheic dermatitis (mild and severe) was determined. The control group consisted of the girth sizes of practically healthy men (n=82) and women (n=154) of the same age group, which were selected from the database of the research center National Pirogov Memorial Medical University. Statistical processing of body circumference was performed in the licensed package “Statistica 6.0” using non-parametric evaluation methods. As a result of studies in patients with seborrheic dermatitis of varying severity of men, compared with practically healthy men, found only greater values of the girth of the shoulder in a relaxed state and thighs, neck (only mild), shin in the upper part and waist (in both cases only with a severe degree), as well as smaller values of the girth of the shoulder in a tense state; and in patients of varying severity of women – greater values of the girth of the shoulder in a relaxed state, thighs, lower legs, neck, waist and all girths of the chest and both thighs (only severe), as well as smaller values of the girth of the hand (only with mild). In both men and women with seborrheic dermatitis, differences in girth body sizes are more pronounced in people with severe disease. Between men or women with seborrheic dermatitis of varying severity, there are no significant or trends in differences in girth body sizes. In the analysis of the manifestations of sexual dimorphism of the circumferential body size between men and women with seborrheic dermatitis found greater values in men with mild and severe disease of the upper extremities, hands, shin, feet and neck (in most cases more pronounced in representatives with mild severity), as well as only in men with mild severity – greater values of all chest girths. For a more correct understanding of changes in girth body sizes in Ukrainian men or women with seborrheic dermatitis of varying severity, it is necessary to analyze other constitutional parameters of the body.

scholarly journals Features of longitudinal and transverse body sizes in men with various forms of eczema

2020 ◽  
Vol 26 (4) ◽  
pp. 16-21
Author(s):  
S.V. Dmytrenko ◽  
Ahmad Al-Omary Ala’a Osama ◽  
І.V. Dzevulska ◽  
R.V. Skoruk ◽  
I.V. Gunas
Keyword(s):  
Lower Extremities ◽  
Data Bank ◽  
Healthy Individuals ◽  
Healthy Men ◽  
Distal Epiphysis ◽  
Constitutional Type ◽  
Upper And Lower Extremities ◽  
Icd 10 ◽  
Body Sizes ◽  
Severe Eczema

Consideration of the aspect of adaptation, in particular morphological, is expedient with obligatory comparison of morphometric indicators in healthy and sick patients and between groups of patients with different degrees of severity of dermatosis. The aim of the study was to investigate the differences between longitudinal and transverse body sizes between healthy and/or patients with eczema men depending on the severity of the dermatosis. Patients with idiopathic (n=34) and microbial (n=38) eczema men of the first mature age underwent an anthropometric examination according to Bunak. The diagnosis of eczema was made according to the nomenclature of ICD-10. As a control from the data bank of the research center of National Pirogov Memorial Medical University, Vinnytsya anthropometric data of 82 practically healthy men of the same age group were selected. Statistical data processing was performed in the license package “Statistica 5.5” using non-parametric methods of evaluation of the obtained results. In healthy men, compared with patients, higher values were found for: the height of the pubic anthropometric point by 3.5-5.7% and the height of the acetabular anthropometric point by 4.9-7.5% compared with sick men with idiopathic mild and severe eczema and mild and severe microbial eczema and lower values for: height of the suprathoracic anthropometric point by 1.7-2.6% for idiopathic eczema of mild, severe course and microbial eczema of mild course; height of the acromial anthropometric point by 1.6-2.3% compared with men with idiopathic eczema of mild and severe course; height of the finger anthropometric point by 3.0-5.9% compared with men with idiopathic eczema of mild and severe course and microbial eczema of mild and severe course. In healthy men, compared with patients, higher values were found: mid-thoracic diameter – by 3.1-11.1%, 5.5-14.4%, transverse lower thoracic diameter – by 8.6-14.1% and anterior-posterior mid-thoracic diameter – by 10.2-16.6% and smaller values: width of shoulders by 15.3-21.1% compared with men with idiopathic eczema of mild and severe course and microbial eczema of mild and severe course. In healthy individuals, the width of the distal epiphysis of the forearm is greater by 3.14% compared with patients with idiopathic severe eczema and the width of the distal epiphysis of the crus by 3.1% compared with patients with microbial eczema of mild course; smaller - the width of the distal epiphysis of the shoulder by 3.0% compared with patients with idiopathic eczema of severe course and the width of the distal epiphysis of the thigh by 5.2-7.6% compared with patients with idiopathic eczema of mild and severe course and microbial eczema of mild course. In healthy individuals, the values of the size of the pelvis are lower: interspinous distance – by 8.3-11.6%, intercristal distance – by 8.7-12.5% and intertrochanteric distance – by 7.7-10.5% compared with sick men with idiopathic mild and severe eczema and microbial eczema of the mild and severe course. Differences in longitudinal body size in patients with different forms and severity of eczema. When comparing anthropometric indicators between sick men, the following were found: the height of pubic and acetabular anthropometric points in sick men with idiopathic eczema of mild course is higher by 1.8% and 1.7%, respectively, compared with sick men with microbial eczema of similar severity; shoulder width in patients with idiopathic eczema of mild course is 4.8% less than in patients with idiopathic eczema of severe course. Thus, men with eczema have a subpathological constitutional type, which is characterized by an elongated “cylindrical” torso, shortened lower extremities, as well as more massive distal and less massive proximal epiphyses of the upper and lower extremities.

scholarly journals Features of the girth sizes of the body in men with various forms of eczema

2020 ◽  
pp. 51-56
Author(s):  
Al-Omary Ala’a Osama Ahmad ◽  
S. V. Dmitrenko ◽  
O. P. Drachuk ◽  
V. V. Yasko ◽  
I. V. Gunas
Keyword(s):  
Data Bank ◽  
The Body ◽  
Healthy Men ◽  
Methods Of Evaluation ◽  
Icd 10 ◽  
Chest Girth ◽  
Personalized Approach ◽  
Severe Eczema ◽  
Medical University ◽  
Microbial N

Prediction of the occurrence of eczema and the development of its severe forms is possible by identifying its morphological markers in patients with various forms and severity of dermatosis and their comparison with healthy subjects. The aim of the study was to examine the differences in body girth sizes between healthy and/or eczema patients depending on the severity of dermatosis. Patients with idiopathic (n=34) and microbial (n=38) eczema men of the first mature age underwent an anthropometric examination according to Bunak. The diagnosis of eczema was made according to the nomenclature of ICD-10. As a control from the data bank of the research center of National Pirogov Memorial Medical University, Vinnytsya anthropometric data of 82 practically healthy men of the same age group were selected. Statistical data processing was performed in the license package “Statistica 5.5” using non-parametric methods of evaluation of the obtained results. In healthy men, the following values of the following envelope sizes were found: shoulder girth in a tense state by 4.9 % compared with patients with severe eczema; unstressed shoulder girth by 7.3 % and 11.8 % compared with patients with idiopathic eczema of mild and severe course and by 10.0 % and 11.3% compared with patients with microbial eczema of mild and severe course; forearm girth in the upper part by 5.4 % compared with patients with idiopathic eczema of severe course; thigh girth by 5.1 % and 8.0 % compared with patients with idiopathic eczema of mild and severe course and by 7.1 % and 11.3 % compared with patients with microbial eczema of mild and severe course; thigh girth by 4.16 % and 4.5 % compared with patients with idiopathic severe eczema and mild microbial eczema; upper crus girth by 5.3 %, 7.5 % and 7.1 % compared with patients with idiopathic eczema of mild and severe course and microbial eczema of mild course; lower crus girth by 6.0 % compared with patients with mild microbial eczema; neck girth by 7.5 % and 6.8 % compared with patients with idiopathic severe eczema and mild microbial eczema; waist girth by 8.6 % and 15.6 % compared with patients with idiopathic eczema of mild and severe course and by 13.9 % and 16.7 % compared with patients with microbial eczema of mild and severe course; chest girth on inhalation, exhalation, at rest by 6.9 %, 9.5 % and 9.1 % compared with patients with idiopathic eczema of severe course. Only the girth of the foot in healthy men is 3.1 % higher than in sick men with mild microbial eczema. In men with idiopathic eczema, the neck girth was 5.4 % lower than in men with severe eczema. The obtained data can be used for a personalized approach in the creation of appropriate prevention and treatment and diagnostic programs.

scholarly journals Features of total, longitudinal and transverse body sizes in men of the general group of patients with mild and severe psoriasis

2020 ◽  
Vol 24 (4) ◽  
pp. 647-652
Author(s):  
S. V. Dmitrenko ◽  
Obadeh Bassam Abdel-Rahman Al-Qaraleh ◽  
І. V. Dzevulska ◽  
R. V. Skoruk ◽  
I. V. Gunas
Keyword(s):  
Body Size ◽  
Body Length ◽  
Data Bank ◽  
Severe Psoriasis ◽  
General Group ◽  
Healthy Men ◽  
Distal Epiphysis ◽  
Body Sizes ◽  
Severity Of The Disease ◽  
Medical University

Annotation. The constitutional approach is a valuable tool in the hands of practicing dermatologists, which allows an individual approach to the diagnosis and treatment of patients with psoriasis. The aim of the study was to examine the differences in total, longitudinal and transverse body sizes between healthy and/or psoriatic men depending on the severity of the disease. Anthropometric examination according to Bunak was performed for 32 men of the first mature age in patients with mild and 68 men with severe psoriasis. The PASI index was used to clinically assess the severity and area of psoriatic lesions. As a control from the data bank of the research center of National Pirogov Memorial Medical University, Vinnytsya anthropometric data of 82 practically healthy men of the same age group were selected. Statistical data processing was performed in the license package “Statistica 5.5” using non-parametric methods of evaluation of the obtained results. In patients with mild and severe psoriasis compared with healthy men found: lower values – pubic height (by 3.2 % and 5.4 %) and trochanter (by 8.2 % and 7.0 %) anthropometric points, shoulder width (by 19.6 % and 19.0 %) and the width of the distal epiphysis of the shin (by 5.2 % and 4.8 %); greater values – body weight (by 20.1 % and 17.5 %), body length (by 1.7 % in mild course), body surface area (by 10.0 % and 7.8 %), height of suprasternal (by 3.0 % and 1.5 %), acromial (by 2.3 % and 1.0 %) and finger (by 6.1 % and 4.4 %) anthropometric points, width of the distal epiphysis of the shoulder (by 6.9 % and 5.7 %), forearm (by 3.3 % in mild course) and thigh (by 10.3 % and 7.1 %), mid-thoracic diameter (by 16.5 % and 16.3 %), transverse lower thoracic diameter (by 16.5 % and 15.7 %), anterior-posterior mid-thoracic diameter (by 17.7 % and 20.2 %), interspinous (by 12.2 % and 12.1 %), intercristal (by 13.4 % and 11.7 %) and intertrochanteric (by 11.3 % and 10.4 %) distances. Differences in the studied body size in patients with varying degrees of psoriasis found. Thus, in patients with mild psoriasis, compared with patients with severe psoriasis, higher values were found for: body length (by 1.6 %); heights of suprasternal (by 1.5 %), pubic (by 2.1 %) and finger (by 1.4 %) anthropometric points; width of the distal epiphysis of the forearm (by 2.3 %). Thus, pronounced differences in total, longitudinal and transverse dimensions between healthy and patients with mild and severe psoriasis were revealed by Ukrainian men of the first mature age. Between patients with varying degrees of severity of dermatosis, most differences are found only for longitudinal body size.

scholarly journals Sonographic model parameters of kidney in men and women endo-mesomorphic somatotype depending on the anthropometric indices characteristics

2018 ◽  
pp. 43-49
Author(s):  
O.S. Ustymenko
Keyword(s):  
The Body ◽  
Absolute Amount ◽  
Model Parameters ◽  
Anthropometric Parameters ◽  
Anthropometric Indices ◽  
Body Dimensions ◽  
Healthy Men ◽  
Body Sizes ◽  
Length Width ◽  
The Right

The application of the mathematical method for establishing quantitative relationshipsbetween the set of anthropometric parameters and sonographic parameters of thepatient allows in some cases to significantly improve early diagnosis of diseases, makeit not only timely, but accurate. The purpose of the work is to analyze the regressionmodels of individual sonographic sizes of the kidneys in practically healthy men andwomen of the endo-mesomorphic somatotype, depending on the peculiarities of thestructure and size of the body. Sonographic renal research conducted using ultrasonicdiagnostic system "CAPASEE" SSA-220A (Toshiba, Japan). For each kidney, the length,width (transverse size) and front and rear dimensions were determined; the area of thelongitudinal and transverse sections of the kidneys and their sinuses, as well as thevolume of the right and left kidneys. All of them had an anthropometric survey conductedby V.V. Bunak in the modification of P. P. Shapаrenko. The evaluation of thesomatotype was carried out according to the mathematical scheme of J. Carter and B.Heath. Determining the absolute amount of fat, bone and muscle components of bodyweight was calculated by the formula J. Matiegka and the muscular component - bythe formulas of the American Institute of Nutrition. For the construction of models ofindividual sonographic parameters of the kidneys, the method of stepwise regressionanalysis in the package "STATISTICA 6.1" was used. In practically healthy men andwomen of Podillia endo-mesomorphic somatotype of 16 possible 14 reliable regressionmodels of sonographic parameters of the right and left kidneys, based on anthropo-somatotypological indicators with a determination coefficient, from 0.767 to 0.966 andfrom 0.672 to 0.912 were constructed. The constructed models of sonographicparameters of both kidneys in men endo-mesomorphic somatotype most often includethe circumferential body dimensions (22.4%), cephalometric indices and the thicknessof skin and fat folds (17.1%), body diameters (14.5%), and longitudinal body dimensions(11.8%). The constructed models of sonographic parameters of both kidneys in womenendo-mesomorphic somatotype most often include circumferential body sizes (23.1%),body diameters (20.5%), cephalometric indices (19.2%) and thickness of skin and fatfolds (16.7%). In the analysis of entering into models of sonographic parameters of thekidneys anthropometric and somatotypological indicators, expressed manifestations ofasymmetry and sexual dimorphism

scholarly journals Manifestations of asymmetry and correlations of sonographic parameters of the kidneys with constitutional parameters of the body in practically healthy men and women of different somatotypes

2018 ◽  
pp. 21-27
Author(s):  
О. S. Ustymenko
Keyword(s):  
Regression Models ◽  
Clinical Medicine ◽  
The Body ◽  
Scientific Cooperation ◽  
Modern Biology ◽  
Healthy Men ◽  
Healthy Women ◽  
Body Sizes ◽  
The Asymmetry ◽  
Genetically Determined

The problem of asymmetry is one of the fundamental in modern biology, theoretical and clinical medicine, it has deep evolutionary roots. Analysis of literature suggests that the coverage of various aspects of morpho-functional asymmetry of the kidneys to this time is not always unambiguous, and sometimes controversial. The purpose of the work is to establish manifestations of asymmetry of entering into regression models of sonographic sizes of kidneys anthropometric and somatotypological parameters of a body in practically healthy women and men of different somatotypes. Within the framework of the agreement on scientific cooperation from the database of the research center of the National Pirogov Memorial Medical University, Vinnytsya taken the primary sonographic parameters, anthropometric and somatotypological indicators of 121 practically healthy women and 97 practically healthy men of the first mature age (correspondingly, of the age from 21 to 35 and from 22 to 35 years old) who in the third generation live on the territory of Podillia region of Ukraine. For the construction of regression models of individual sonographic sizes of the kidneys, depending on the peculiarities of anthropo-somatotypological parameters of the body, the license package “Statistica 6.1” was used. To analyze the asymmetry of entering into regression models of sonographic sizes of anthropo-somatotypological indicators, all constructed reliable models, but not only models with a determination coefficient of greater than 0.6, were taken into account. Also, in the analysis, anthropometric and somatotypological indicators refer either to highly genetically determined (longitudinal body sizes, cephalometric indexes, width of distal epiphyses of long tubular limb bones, trunk diameters, pelvic sizes, ectomorphic component of somatotype, bone component of body weight) or to low genetically determined (mass, body surface area, body dimensions thickness of skin fat folds, endomorphic and mesomorphic components of the somatotype, muscle and fat components of the body mass). In men of various somatotypes, when analyzing the asymmetry of entering the models of sonographic sizes of the anthropometric and somatotypological indicators of kidneys, it has been established: in the mesomorphic somatotype representatives - 84.1% (among which 50.0% belong to highly genetically determined indices), in the representatives of the ecto-mesomorphic somatotype - 86.0% (among which 46.5% belong to highly genetically determined indicators), in the representatives of the endo-mesomorphic somatotype - 88.1% (among which 51.4% belong to a highly genetically determined indices). In women of various somatotypes, when analyzing the asymmetry of entering the models of sonographic sizes of the anthropometric and somatotypological indicators of kidneys, it was established:), in the representatives of the mesomorphic somatotype - 82.0% (among which 51.2% belong to highly genetically determined indices), in the representatives of the ectomorphic somatotype – 89.0% (among which 58.0% belong to highly genetically determined indicators), in the representatives of the endo-mesomorphic somatotype - 83.3% (among which 50.0% belong to highly genetically determined indicators), in the representatives of middle intermediate somatotype - 82.5% (among which 56.5% belong to highly genetically determined indicators).

Erythrocyte and reticulocyte parameters during biological monitoring of lead exposure to the body

2020 ◽  
Vol 60 (11) ◽  
pp. 873-876
Author(s):  
Anastasiya G. Khotuleva ◽  
Mariya S. Kozyreva
Keyword(s):  
Biological Monitoring ◽  
Hematological Parameters ◽  
Lead Level ◽  
Statistical Processing ◽  
Absorption Spectrometry ◽  
The Body ◽  
Control Group ◽  
Processing Plant ◽  
Hematological Disorders ◽  
Globin Synthesis

Introduction. The most susceptible to lead is the hematopoietic system of hematopoietic organs due to lead inhibition of heme and globin synthesis and cytotoxic effect on the membrane of Mature red blood cells. The aim of study was to evaluate the informative value of the study of erythrocyte and reticulocyte parameters determined on modern hematological analyzers in patients working in contact with lead during medical and biological monitoring. Materials and methods. 45 employees of the lead battery processing plant and 30 persons of control group were examined. The level of lead in the blood was determined by atomic absorption spectrometry, δ-ALA in the urine-by the reaction of pyrol formation with acetylacetone in terms of gram of creatinine, the study of hematological parameters was performed on a Sysmex HT-2000i analyzer. Statistical processing of the results was performed using the program STATISTICA 10.0. Results. Significant changes in erythrocytic (RDW) and reticulocytic (RET, IRF, LFR, MFR, HFR, RET-He) parameters, erythropoietin in workers in contact with lead compared to the control group, changes in MCV, MCH, RDW, RET indicators in the group working in dynamics after 2 years were revealed. Associations of hematological parameters with biomarkers of exposure and effect (lead level in blood and ALA in urine) were revealed. Conclusions. Assessment of erythrocyte (MCV, MCH, RDW) and reticulocyte parameters (RET% and their distribution by maturity) in dynamics during periodic medical examinations of workers in contact with lead allows us to detect the development of hematological disorders at early stages.

scholarly journals The Association of Obesity and Liver Enzyme Activities in a Student Population at Increased Risk for Cardiovascular Disease / Veza Između Gojaznosti I Aktivnosti Jetrenih Enzima U Studentskoj Populaciji Sa Povećanim Rizikom Za Nastanak Kardiovaskularnih Bolesti

2013 ◽  
Vol 32 (1) ◽  
pp. 26-31 ◽  
Author(s):  
Emina Čolak ◽  
Dragana Pap ◽  
Nada Majkić-Singh ◽  
Ivana Obradović
Keyword(s):  
Body Mass Index ◽  
Waist Circumference ◽  
Liver Enzyme ◽  
Body Mass ◽  
Statistical Processing ◽  
The Body ◽  
Control Group ◽  
Anthropometric Parameters ◽  
Nonalcoholic Fatty Liver ◽  
Increased Risk

Summary Background: It has been reported that obesity is associated with metabolic syndrome, insulin resistance, cardiovascular risk but also with nonalcoholic fatty liver disease (NAFLD). The prevalence of obesity in children and adolescents is increasing rapidly all over the world. The aim of this study was to analyze the value of liver enzymes: AST, ALT and γGT in a group of obese students in order to establish their correlation to anthropometric parameters such as: BMI (body mass index), WC (waist circumference), HC (hip circumference), and WHR (waist-to-hip ratio) compared to non-obese students who comprised the control group (CG). Methods: In this study, 238 students from the University of Novi Sad of both sexes (126 men and 112 women) with a mean age of 22.32 ± 1.85 years were included. According to the body mass index (BMI) lower and higher than 25 kg/m2 and waist circumference (WC) lower and higher than 94 cm (80 cm for females) the whole group of 238 students was divided into 2 subgroups: the obese group at increased risk for CVD (Group 1) and the group at lower risk for CVD (Group 2). AST, ALT and γGT activities were determined in fasting blood samples. Results: Statistical processing data revealed significantly higher values of AST, ALT and γGT in the group of students with BMI>25 kg/m2, WC>94 cm for males and WC>80 cm for females, HC>108 cm for males and HC>111 cm for females, and WHR>0.90 for males and WHR>0.80 for females (P<0.001). Significant association was established between anthropometric parameters and liver enzyme levels (P<0.0001). Conclusions: Obese students with higher BMI, WC, HC and WHR values have higher liver enzyme activites and a higher chance to develop NAFLD in the future.

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