Study to Assess the Way the Body Absorbs, Distributes, Breaks Down and Eliminates Radioactive BMS-986256 in Healthy Male Participants

Author(s):  
Keyword(s):  
The Body ◽  
Author(s):  
Varsha Gupta ◽  
Lipika Singhal ◽  
Kritika Pal ◽  
Mani Bhushan ◽  
Rajeev Sharma ◽  
...  

Introduction: Human Salmonella infections have been classically distinguised into diseases caused by typhoidal and non-typhoidal salmonella (NTS). Typhiodal salmonella includes S. enterica serovars Typhi and Paratyphi that cause the systemic disease but are restricted to human infections, while NTS consists mainly of other serovars that predominantly cause self-limiting gastroenteritis in humans. Localisation of foci with persisting infection occurs due to dissemination of the bacteria throughout the body and can cause a variety of rare clinical syndromes at aberrant sites. Fournier’s gangrene, a rapidly progressive, often fatal, necrotizing fasciitis of the external genitalia and perineum due to Salmonella Typhimurium, is a rare manifestation and has never been reported. Case: A 22-year-old male, apparently healthy patient with no relevant past medical history presented to surgical emergency with chief complaints of swelling of bilateral scrotal area. Infective etiology was considered and a diagnosis of fournier’s gangrene was made. Pure growth of Salmonella Typhimurium was obtained after repeated subculture and was identified biochemically and on serotyping, as Salmonella enterica serotype Typhimurium using specific antisera. Conclusion: In our case report, we describe a case of fournier’s gangrene due to Salmonella Typhimurium in an otherwise healthy male to highlight the unusual presentation of Non typhoidal salmonellae at an aberrant site. We also emphasize the importance of using selective media like Selenite F broth for isolation of Salmonella Typhimurium from a pus sample.


Human Studies ◽  
2021 ◽  
Author(s):  
Jenny Slatman

AbstractThis paper aims to mobilize the way we think and write about fat bodies while drawing on Jean-Luc Nancy’s philosophy of the body. I introduce Nancy’s approach to the body as an addition to contemporary new materialism. His philosophy, so I argue, offers a form of materialism that allows for a phenomenological exploration of the body. As such, it can help us to understand the lived experiences of fat embodiment. Additionally, Nancy’s idea of the body in terms of a “corpus”—a collection of pieces without a unity—together with his idea of corpus-writing—fragmentary writing, without head and tail—can help us to mobilize fixed meanings of fat. To apply Nancy’s conceptual frame to a concrete manifestation of fat embodiment, I provide a reading of Roxane Gay’s memoir Hunger (2017). In my analysis, I identify how the materiality of fat engenders the meaning of embodiment, and how it shapes how a fat body can and cannot be a body. Moreover, I propose that Gay’s writing style—hesitating and circling – involves an example of corpus-writing. The corpus of corpulence that Gay has created gives voice to the precariousness of a fat body's materialization.


2011 ◽  
Vol 2011 ◽  
pp. 1-8 ◽  
Author(s):  
R. Francik ◽  
M. Krośniak ◽  
M. Barlik ◽  
A. Kudła ◽  
R. Gryboś ◽  
...  

The aim of this study was to investigate the clinical efficacy of vanadium complexes on triglycerides (TG), total cholesterol (Chol), uric acid (UA), urea (U), and antioxidant parameters: nonenzymatic (FRAP—ferric reducing ability of plasma, and reduced glutathione—GSH) and enzymatic (glutathione peroxidase—GPx, catalase—CAT, and GPx/CAT ratio) activity in the plasma of healthy male Wistar rats. Three vanadium complexes: [VO(bpy)2]SO4⋅2H2O, [VO(4,4′Me2bpy)2]SO4⋅2H2O, and Na[VO(O2)2(bpy)]⋅8H2O are administered by gavage during 5 weeks in two different diets such as control (C) and high fatty (F) diets. Changes of biochemical and antioxidants parameters are measured in plasma. All three vanadium complexes statistically decrease the body mass growth in comparison to the control and fatty diet. In plasma GSH was statistically increased in all vanadium complexes-treated rats from control and fatty group in comparison to only control group. Calculated GPX/CAT ratio was the highest in the control group in comparison to others.


Author(s):  
Ying San, Lim ◽  
Phing Cai ◽  
Andy Hong ◽  
Tuan Hock, Ng ◽  
Ying Zhee, Lim

The cosmetics and toiletry industry has growing up very fast. In 2016, the total global revenue cosmetics industry amounted to USD$444 billion. According to Lee, Goh, & Noor ( 2019), the skincare products dominated the cosmetics and toiletry market with a market value of approximately USD$ 120 billion. Between 2012 and 2019, the global skincare market expanded by 41.8 percent, and by 2025, it is expected to be worth $189 billion (Ledesma, 2020). The skin is the largest organ in the body, hence, many people will find ways to protect it, one of the way people are using to protect the skin is to apply any supplement on skin to keep the good condition of the skin. However, according to Cunningham (2014), the used of chemical items in the cosmetic skin care industry is extremely unregulated. For example, Parabens that cause breast cancer are found in cosmetics. The chemical used in the skin care products had rise the attention of the users to start to pay attention on the ingredient of the skin care products. One of the way people are using in order to avoid the harmful chemical in skin care products is to to choose skin care with natural ingredient (Espitia, 2020), this happend especially among the younger consumers (Boon et al., 2020; Hsu et al.,2017). The green skincare industry is growing rapidly. Green skin care, according to previous studies (Fauzi & Hashim, 2015; Hsu et al., 2017), is any skin care products which can preserve or enhance the natural environment by conserving energy or resources and decreasing or eliminating the usage of harmful agents, pollution, and waste. Studies showed there is an increasing in the consumption of green skincare products and toiletries by 45%, from a peak of RM 1.6 billion (in 1998) to RM 2.2 billion (in 2010), with sales estimated to exceed $1.1 billion in 2010 among young people (Boon et al., 2020). Keywords: Green Skin Care, Generation Z, Theory Of Planned Behaviour


2021 ◽  
Vol 51 (3) ◽  
pp. 533-551
Author(s):  
Laura Levine
Keyword(s):  
The Body ◽  

Toward the end of the 1628 pamphlet A Briefe Description of the Notorious Life of Iohn Lambe, the pamphleteer describes the violence a crowd inflicts on John Lambe, a cunning man who dabbled in the dark arts. This violence, ultimately fatal, seems to be a response to Lambe's rape of an eleven-year-old child, a rape which he is convicted of but ultimately pardoned for. Earlier in his career, however, Lambe is indicted for using magic to disable the body of a gentleman as well as for invoking evil spirits. What connection exists between the charges against Lambe as a witch and magician and the charges against him as a rapist? This essay argues that long before Lambe gives those around him a basis for violence, he triggers anxieties about what he is, and that these anxieties play a role in the violence against him. The text of A Briefe Description demonstrates the way mechanisms of justice ultimately repeat—reenact and perform—versions of the crimes they seek to examine.


2017 ◽  
Vol 31 (1) ◽  
pp. 65-78
Author(s):  
Justin Nickel

Stanley Hauerwas and others argue that Luther’s understanding of justification denies the theological and ethical significance of the body. Indeed, the inner, spiritual person is the one who experiences God’s grace in the gospel, while the outer, physical (read: bodily) person continues to live under law and therefore coercion and condemnation. While not denying that Luther can be so read, I argue that there is another side of Luther, one that recognizes the body’s importance for Christian life. I make this argument through a close reading of Luther’s reflections on Adam and Eve’s Fall in his Lectures on Genesis (1545) and the sacramental theology in ‘Against the Heavenly Prophets’. For this Luther, disconnection from our bodies is not a sign of justification but rather the sin from which justification saves us. Accordingly, justification results in a return to embodied creatureliness as the way we receive and live our justification.


Divine Bodies ◽  
2019 ◽  
pp. 1-21
Author(s):  
Candida R. Moss

The resurrection of the body is a key place to think about who we are and which facets of ourselves are integral to ourselves. The introduction to this book places the resurrection of the body within the context of ancient anxieties about the self: What makes us who we are? It also reviews the history of scholarship on this question and traces the way that ideas about resurrection have been divorced from broader thinking about the self.


Author(s):  
Luis Raul Meza Mendoza ◽  
María Elena Moya Martinez ◽  
Angelica Maria Sabando Suarez

Since the beginning of humanity, an attempt has been made to explain the way in which man acquires knowledge, the way in which he assimilates, processes and executes it in order to develop the teaching-learning process that people need throughout of his life, which forces to change the learning schemes using new study methodologies, such as neuroscience, which is a discipline that studies the functioning of the brain, the relationship of neurons to the formation of synapses creating immediate responses which transmits to the body voluntarily and involuntarily, in addition to controlling the central and peripheral nervous system with their respective functions. It is necessary to change the traditional scheme and implement new strategies that allow the teacher to venture into neuroscience, in order to individually understand the different learning processes that students do. As some authors of neuroscience say, the brain performs processes of acquisition, storage and evocation of information, which form new knowledge schemes that generate changes in the attitude of the human being, for this reason teachers are responsible for taking advantage of what It is known about the multiple functions of the brain and be clear about the various ways of acquiring knowledge.


2014 ◽  
Vol 9 (18) ◽  
pp. 35
Author(s):  
Jaime Tomás Page Pliego

Suele asumirse que la noción de persona es igual entre los pueblos de tsotsiles y tesltales de los Altos de Chiapas. Sin embargo, su configuración varía sustancialmente, sin perder la base que los une. Este trabajo trata sobre las diferencias y similitudes que se presentan en el concepto denominado complejo persona en tres municipios: Oxchuc —de habla tseltal—, Chamula y Chenalhó —de habla tsotsil—, y en forma destacada sobre la importancia del cuerpo en dicho concepto. Asimismo, se abordan las variaciones que se han suscitado en torno a esa noción a partir de 1940, bajo la incidencia de la escalada proselitista cristiana. THE IMPORTANCE OF THE BODY WITHIN THE COMPLEX OF THE NOTION OF PERSONHOOD AMONG CONTEMPORARY MAYANS FROM OXCHUC, CHAMULA AND CHENALHÓ IN CHIAPAS STATE There is a tendency to assume that the Tsotsil and Tseltal communities in the Chiapas Highlands (Altos de Chiapas) share the same notion of personhood. However, the way this notion is constructed does vary substantially without losing a common foundation. This piece of research deals with the similarities and differences present in the concept of personhood complex in three different municipalities: Oxchuc —a tseltal-speaking community—, Chamula and Chenalhó —tsotsil-speaking communities—, and emphasizes the importance of the body in this concept. It also addresses the permutations that have emerged around this notion since 1940, under the escalating influence of Christian proselytism.


Sign in / Sign up

Export Citation Format

Share Document