Differences in leukocyte profile, gene expression, and metabolite status of dairy cows with or without sole ulcers

This research communication describes the profile of gene expression related to the synthesis of yak milk as determined via quantitative reverse transcription polymerase chain reaction (RT-qPCR). Significant up-regulation during lactation were observed in genes related to fatty acid (FA) uptake from blood (LPL, CD36), intracellular FA transport (FABP3), intracellular FA activation of long- and short-chain FAs (ACSS1, ACSS2, ACSL1), de novo synthesis (ACACA), desaturation (SCD), triacyglycerol (TAG) synthesis (AGPAT6, GPAM, LPIN1), lipid droplet formation (PLIN2, BTN1A1, XDH), ketone body utilisation (BDH1, OXCT1), and transcription regulation (THRSP, PPARGC1A). In particular, intracellular de novo FA synthesis (ACSS2, ACACA, and FABP3) and TAG synthesis (GPAM, AGPAT6, and LPIN1), whose regulation might be orchestrated as part of the gene network under the control of SERBF1 in the milk fat synthesis process, were more activated compared to levels in dairy cows. However, the genes involved in lipid droplet formation (PLIN2, XDH, and BTN1A1) were expressed at lower levels compared to those in dairy cows, where these genes are mainly controlled by the PPARG regulator.

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Function and gene expression of circulating neutrophils in dairy cows : impact of micronutrient supplementation

10.32469/10355/15896 ◽

2012 ◽

Author(s):

Xavier S. Revelo

Keyword(s):

Gene Expression ◽

Dairy Cows ◽

Micronutrient Supplementation

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445 Toxy-Nil and Unike Plus modulate differences in gene expression of milk somatic cells isolated from mammary gland of lactating dairy cows fed aflatoxin B1

Journal of Animal Science ◽

10.2527/asasann.2017.445 ◽

2017 ◽

Vol 95 (suppl_4) ◽

pp. 218-219

Author(s):

R. O. Rodrigues ◽

D. R. Ledoux ◽

G. E. Rottinghaus ◽

R. Borutova ◽

...

Keyword(s):

Gene Expression ◽

Mammary Gland ◽

Dairy Cows ◽

Aflatoxin B1 ◽

Somatic Cells ◽

Lactating Dairy Cows ◽

Milk Somatic Cells

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Effect of overconditioning on the hepatic global gene expression pattern of dairy cows at the end of pregnancy

Journal of Dairy Science ◽

10.3168/jds.2020-19302 ◽

2021 ◽

Author(s):

O. Bogado Pascottini ◽

J. De Koster ◽

F. Van Nieuwerburgh ◽

M. Van Poucke ◽

L. Peelman ◽

...

Keyword(s):

Gene Expression ◽

Dairy Cows ◽

Expression Pattern ◽

Gene Expression Pattern ◽

Global Gene Expression ◽

Global Gene Expression Pattern

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Prevalence and distribution of feet lesions in dairy cows raised in the freestall

Semina Ciências Agrárias ◽

10.5433/1679-0359.2019v40n1p239 ◽

2019 ◽

Vol 40 (1) ◽

pp. 239 ◽

Cited By ~ 1

Author(s):

Rafael Costa Ebling ◽

Amanda Krummenauer ◽

Gustavo Machado ◽

Diego Zeni ◽

Luis Paulo Carazzo ◽

...

Keyword(s):

Dairy Cows ◽

Body Condition Score ◽

The Body ◽

Economic Losses ◽

Productivity Losses ◽

Foot Diseases ◽

Infectious Origin ◽

Condition Score ◽

Foot Lesions ◽

Sole Ulcers

Foot lesions are one of the main causes of productivity losses in the dairy industry. In this study, we aimed to estimate the prevalence of claudication and distribution of hoof lesions by associating them with preventive hoof trimming, as well as list the main causes of involuntary discarding and the main health problems reported in dairy farms. The study included 10 farms distributed in 7 municipalities of Rio Grande do Sul state. The body condition score (BCS) and locomotion score (LS) of the cows were assessed. Hoof examination, lesion classification, and hoof trimming of the animals were performed. Of the 492 animals, 38.4% presented lameness and 36% had foot lesions, 81.4% of which were observed in the pelvic limbs and 19.6% in the thoracic limbs. Of the lesions in the limbs, 47.1% were of infectious origin and 52.9% were noninfectious. The main lesions were sole ulcers (31.6%), digital dermatitis (30.3%), thin soles (12%), and interdigital dermatitis (11.2%). Cows aged 4 to 6 years had a higher number of lesions and a higher LS. Preventive hoof trimming reduced the chances of lameness by 55% as the locomotive system was the main sanitary problem and the first reason for involuntary disposal of the farms. The results show that dairy cows raised in a free stall system have a high prevalence of claudication and foot diseases. These data should be taken into account when altering the livestock management of these animals in order to reduce significant economic losses in the herd.

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