scholarly journals Use of Fluorescent Probe for the Fast and Quantitative Detection of Chemicals in the Blood

2019 ◽  
Vol IV (I) ◽  
pp. 1-10
Author(s):  
Urooj Naseem ◽  
Ayesha Ayub ◽  
Fatima Iqbal ◽  
Farhan Sohail
Keyword(s):  
Detection Limit ◽  
Chemical Analysis ◽  
Fluorescent Probe ◽  
Fluorescent Probes ◽  
Incubation Time ◽  
High Selectivity ◽  
Mixing Time ◽  
Detection Limits ◽  
Quantitative Detection ◽  
Spatiotemporal Resolution

Different methods are adopted for the quantitative detection of chemicals in the blood. One of which is discussed here, i.e., the fluorescent probes that are preferred in biological systems owing to their sensitivity, high selectivity, elevated spatiotemporal resolution, and noninvasiveness. In recent years, for the identification of various chemicals, a large number of probes have been designed. For the detection as well as identification of fluorescent probes, sulfides, different chemicals such as iron, glucose, glutathione etc., in the blood are discussed. The maximum detection limits of newly synthesized fluorescent probes for different chemical analysis are studied and comparatively analyzed. Different parameters like pH, incubation time, mixing time, the detection limit of the fluorescent probes is also explored.

Colorimetric and Fluorescent Probe for Hypochlorite with High Selectivity

2013 ◽  
Vol 295-298 ◽  
pp. 475-478 ◽  
Author(s):  
Zhi Xiang Han ◽  
Ming Hui Du ◽  
Guo Xi Liang ◽  
Xiang Yang Wu
Keyword(s):  
Reactive Oxygen Species ◽  
Aqueous Solution ◽  
Detection Limit ◽  
Fluorescent Probe ◽  
Rhodamine B ◽  
High Selectivity ◽  
Reactive Oxygen ◽  
Living Cells ◽  
Oxygen Species ◽  
Turn On

Rhodamine B thiohydrazide (RBS) was firstly employed as turn-on fluorescent probe for hypochlorite in aqueous solution and living cells. It exhibits a stable response to hypochlorite from 1.0×10-6to 1.0×10-5M with a detection limit of 3.3×10-7M. The response of this probe to hypochlorite is fast and highly selective compared with other reactive oxygen species (such as.OH,1O2, H2O2) and other common anions (such as X-, ClO2-, ClO4-, NO3-, NO2-, OH-, Ac-, CO32-, SO42-).

scholarly journals A Turn-On Fluorescent Probe for Sensitive Detection of Cysteine in a Fully Aqueous Environment and in Living Cells

2018 ◽  
Vol 2018 ◽  
pp. 1-8 ◽  
Author(s):  
Xiaohua Ma ◽  
Guoguang Wu ◽  
Yuehua Zhao ◽  
Zibo Yuan ◽  
Yu Zhang ◽  
...  
Keyword(s):  
Detection Limit ◽  
Fluorescent Probe ◽  
High Selectivity ◽  
Coumarin Derivative ◽  
Living Cells ◽  
Sensitive Detection ◽  
Aqueous Environment ◽  
Test Probe ◽  
Aqueous Buffer ◽  
Turn On

We reported here a turn-on fluorescent probe (1) for the detection of cysteine (Cys) by incorporating the recognition unit of 2,4-dinitrobenzenesulfonyl ester (DNBS) to a coumarin derivative. The structure of the obtained probe was confirmed by NMR and HRMS techniques. The probe shows a remarkable fluorescence off-on response (∼52-fold) by the reaction with Cys in 100% aqueous buffer. The sensing mechanism was verified by the HPLC test. Probe 1 also displays high selectivity towards Cys. The detection limit was calculated to be 23 nM. Moreover, cellular experiments demonstrated that the probe is highly biocompatible and can be used for monitoring intracellular Cys.

Screening and application of boron difluoride complexes of curcumin as colorimetric and ratiometric fluorescent probes for bisulfite

2020 ◽  
Vol 12 (11) ◽  
pp. 1514-1521
Author(s):  
Yi Zhang ◽  
Liangping Tu ◽  
Lingling Lu ◽  
Yuxiao Li ◽  
Linjiang Song ◽  
...  
Keyword(s):  
Fluorescent Probe ◽  
Fluorescent Probes ◽  
High Selectivity ◽  
Boron Difluoride ◽  
Ratiometric Fluorescent Probe

Difluoroboron-complexed curcumin was developed as a colorimetric and ratiometric fluorescent probe for HSO3− with high selectivity and sensitivity.

A ratiometric fluorescent probe for rapid and sensitive visualization of hypochlorite in living cells

RSC Advances ◽  
2014 ◽  
Vol 4 (81) ◽  
pp. 43110-43113 ◽  
Author(s):  
Jiayu Zha ◽  
Boqiao Fu ◽  
Caiqin Qin ◽  
Lintao Zeng ◽  
Xichao Hu
Keyword(s):  
Detection Limit ◽  
Fluorescent Probe ◽  
High Selectivity ◽  
Fast Response ◽  
Living Cells ◽  
Low Detection Limit ◽  
Colorimetric Response ◽  
Ratiometric Fluorescent Probe

A novel fluorescent probe displayed a colorimetric response to ClO− with high selectivity, fast response and a low detection limit (0.08 μM).

A highly selective two-photon fluorescent probe for the determination of mercury ions

The Analyst ◽  
2015 ◽  
Vol 140 (9) ◽  
pp. 3285-3289 ◽  
Author(s):  
Fang Liu ◽  
Changqin Ding ◽  
Ming Jin ◽  
Yang Tian
Keyword(s):  
Detection Limit ◽  
Fluorescent Probe ◽  
High Selectivity ◽  
Fluorescent Sensor ◽  
Mercury Ions ◽  
Two Photon ◽  
Specific Recognition ◽  
Low Detection Limit ◽  
Recognition Molecule

A two-photon fluorescent sensor ATD was developed for Hg2+ determination with high selectivity and low detection limit, in which two-photon fluorophore TD was designed and synthesized with a specific recognition molecule for Hg2+ – PT.

Tb-MOF: a naked-eye and regenerable fluorescent probe for selective and quantitative detection of Fe3+and Al3+ions

RSC Advances ◽  
2016 ◽  
Vol 6 (97) ◽  
pp. 94622-94628 ◽  
Author(s):  
Mengfei Zhang ◽  
Jing Han ◽  
Haipeng Wu ◽  
Qing Wei ◽  
Gang Xie ◽  
...  
Keyword(s):  
Fluorescent Probe ◽  
High Selectivity ◽  
Quantitative Detection ◽  
Naked Eye

A unique Tb-MOF fluorescent probe has features that are visible to the naked-eye and can be regenerated; it presents high selectivity and sensitivity to the quantitative detection of Fe3+and Al3+ions.

scholarly journals A new 3-hydroxyphthalimide-based turn-on fluorescent probe for Hg2+ detection in aqueous solution

2020 ◽  
Vol 44 (5-6) ◽  
pp. 349-353
Author(s):  
Xue-Tao Pan ◽  
Qiao Li ◽  
Yuan-Yuan Xu ◽  
Sheng-Li Hu
Keyword(s):  
Aqueous Solution ◽  
Excited State ◽  
Detection Limit ◽  
Fluorescent Probe ◽  
High Selectivity ◽  
Intramolecular Proton Transfer ◽  
Recognition Mechanism ◽  
Turn On ◽  
Transfer Mechanisms ◽  
Analytical Detection

A new 3-hydroxyphthalimide-based turn-on fluorescent probe is designed and synthesized. This probe can be used to determine the presence of Hg2+ ions by fluorescence spectroscope with high selectivity over other metal ions in aqueous solution. The analytical detection limit for Hg2+ is as low as 6.5 × 10−7 M. The recognition mechanism is attributed to Hg2+-promoted carbonothioate group cleavage and a subsequent excited-state intramolecular proton transfer mechanisms.

A colorimetric and ratiometric fluorescent probe with ultralow detection limit and high selectivity for phosgene sensing

2019 ◽  
Vol 163 ◽  
pp. 489-495 ◽  
Author(s):  
Peilian Liu ◽  
Na Liu ◽  
Cuiling Liu ◽  
Yongmei Jia ◽  
Liping Huang ◽  
...  
Keyword(s):  
Detection Limit ◽  
Fluorescent Probe ◽  
High Selectivity ◽  
Ratiometric Fluorescent Probe

A colorimetric and ratiometric fluorescent probe for the rapid and sensitive detection of sulfite in sugar

2016 ◽  
Vol 8 (7) ◽  
pp. 1572-1576 ◽  
Author(s):  
Xiaoming Jiang ◽  
Junchao Xu ◽  
Youlai Zhang ◽  
Hongying Wang ◽  
Lintao Zeng ◽  
...  
Keyword(s):  
Detection Limit ◽  
Fluorescent Probe ◽  
High Selectivity ◽  
Fast Response ◽  
Sensitive Detection ◽  
Low Detection Limit ◽  
Ratiometric Fluorescent Probe

A colorimetric and ratiometric fluorescent probe shows a fast response and high selectivity towards sulfite with a low detection limit (12 nM).

Triphenylamine-decorated BODIPY fluorescent probe for trace detection of picric acid

RSC Advances ◽  
2015 ◽  
Vol 5 (106) ◽  
pp. 87157-87167 ◽  
Author(s):  
Ma Hengchang ◽  
Zhang Zhongwei ◽  
Jin Yuanyuan ◽  
Zha Lajia ◽  
Qi Chunxuan ◽  
...  
Keyword(s):  
Detection Limit ◽  
Fluorescent Probe ◽  
High Selectivity ◽  
Picric Acid ◽  
Trace Detection ◽  
Low Detection Limit ◽  
Near Ir

The near-IR photoactive material TBMA demonstrated high selectivity and sensitivity for picric acid detection with low detection limit and high quenching constant.

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