scholarly journals Use of diffusion tensor imaging in glioma resection

2013 ◽  
Vol 34 (4) ◽  
pp. E1 ◽  
Author(s):  
Kalil G. Abdullah ◽  
Daniel Lubelski ◽  
Paolo G. P. Nucifora ◽  
Steven Brem
Keyword(s):  
Diffusion Tensor Imaging ◽  
Diffusion Tensor ◽  
Low Grade ◽  
Future Directions ◽  
Conventional Mri ◽  
Scientific Principles ◽  
Glioma Resection ◽  
Anatomical Information ◽  
The Brain ◽  
Diffusion Tensor Imaging Dti

Diffusion tensor imaging (DTI) is increasingly used in the resection of both high- and low-grade gliomas. Whereas conventional MRI techniques provide only anatomical information, DTI offers data on CNS connectivity by enabling visualization of important white matter tracts in the brain. Importantly, DTI allows neurosurgeons to better guide their surgical approach and resection. Here, the authors review basic scientific principles of DTI, include a primer on the technology and image acquisition, and outline the modality's evolution as a frequently used tool for glioma resection. Current literature supporting its use is summarized, highlighting important clinical studies on the application of DTI in preoperative planning for glioma resection, preoperative diagnosis, and postoperative outcomes. The authors conclude with a review of future directions for this technology.

scholarly journals Magnetic resonance diffusion tensor imaging in psychiatry: a narrative review of its potential role in diagnosis

2020 ◽  
Author(s):  
Piotr Podwalski ◽  
Krzysztof Szczygieł ◽  
Ernest Tyburski ◽  
Leszek Sagan ◽  
Błażej Misiak ◽  
...  
Keyword(s):  
Diffusion Tensor Imaging ◽  
White Matter ◽  
Magnetic Resonance ◽  
Potential Role ◽  
Diffusion Tensor ◽  
Mean Diffusivity ◽  
Water Molecules ◽  
Mental Diseases ◽  
The Brain ◽  
Diffusion Tensor Imaging Dti

Abstract Diffusion tensor imaging (DTI) is an imaging technique that uses magnetic resonance. It measures the diffusion of water molecules in tissues, which can occur either without restriction (i.e., in an isotropic manner) or limited by some obstacles, such as cell membranes (i.e., in an anisotropic manner). Diffusion is most often measured in terms of, inter alia, fractional anisotropy (FA), mean diffusivity (MD), radial diffusivity (RD), and axial diffusivity (AD). DTI allows us to reconstruct, visualize, and evaluate certain qualities of white matter. To date, many studies have sought to associate various changes in the distribution of diffusion within the brain with mental diseases and disorders. A better understanding of white matter integrity disorders can help us recognize the causes of diseases, as well as help create objective methods of psychiatric diagnosis, identify biomarkers of mental illness, and improve pharmacotherapy. The aim of this work is to present the characteristics of DTI as well as current research on its use in schizophrenia, affective disorders, and other mental disorders.

Diffusion tensor imaging (DTI) of the brain in moving subjects: Application to in-utero fetal and ex-utero studies

2009 ◽  
Vol 62 (3) ◽  
pp. 645-655 ◽  
Author(s):  
Shuzhou Jiang ◽  
Hui Xue ◽  
Serena Counsell ◽  
Mustafa Anjari ◽  
Joanna Allsop ◽  
...  
Keyword(s):  
Diffusion Tensor Imaging ◽  
Diffusion Tensor ◽  
In Utero ◽  
The Brain ◽  
Diffusion Tensor Imaging Dti

Diffusion tensor imaging in schizophrenia

2008 ◽  
Vol 23 (4) ◽  
pp. 255-273 ◽  
Author(s):  
Marinos Kyriakopoulos ◽  
Theodoros Bargiotas ◽  
Gareth J. Barker ◽  
Sophia Frangou
Keyword(s):  
Diffusion Tensor Imaging ◽  
White Matter ◽  
Diffusion Tensor ◽  
Brain Regions ◽  
Basic Principles ◽  
Future Directions ◽  
White Matter Abnormalities ◽  
Non Invasive ◽  
Brain White Matter ◽  
Diffusion Tensor Imaging Dti

AbstractDiffusion tensor imaging (DTI) is a magnetic resonance imaging technique that is increasingly being used for the non-invasive evaluation of brain white matter abnormalities. In this review, we discuss the basic principles of DTI, its roots and the contribution of European centres in its development, and we review the findings from DTI studies in schizophrenia. We searched EMBASE, PubMed, PsychInfo, and Medline from February 1998 to December 2006 using as keywords ‘schizophrenia’, ‘diffusion’, ‘tensor’, and ‘DTI’. Forty studies fulfilling the inclusion criteria of this review were included and systematically reviewed. White matter abnormalities in many diverse brain regions were identified in schizophrenia. Although the findings are not completely consistent, frontal and temporal white matter seems to be more commonly affected. Limitations and future directions of this method are discussed.

scholarly journals GP.05 Intraoperative acquisition of diffusion tensor imaging in cranial neurosurgery: readout-segmented DTI versus standard single-shot DTI

2019 ◽  
Vol 46 (s1) ◽  
pp. S7
Author(s):  
CA Elliott ◽  
B Wheatley ◽  
H Danyluk ◽  
K Au ◽  
KE Aronyk ◽  
...  
Keyword(s):  
Diffusion Tensor Imaging ◽  
White Matter ◽  
Diffusion Tensor ◽  
High Grade Glioma ◽  
Low Grade ◽  
Single Shot ◽  
Planar Imaging ◽  
Susceptibility Artifact ◽  
Echo Planar ◽  
Diffusion Tensor Imaging Dti

Background: Diffusion-tensor imaging (DTI) tractography is commonly used in neurosurgical practice, but is largely limited to the preoperative setting. This is due primarily to image degradation caused by susceptibility artifact when conventional single-shot (SS) echo-planar imaging DTI is acquired for open cranial, surgical position intraoperative DTI (iDTI). A novel, artifact-resistant, readout-segmented (RS) DTI has not yet been evaluated in the intraoperative MRI (iMRI) environment. Our objective was to evaluate the performance of RS-DTI versus SS-DTI for intraoperative white matter imaging. Methods: Pre- and intraoperative 3T, T1-weighted and DTI (RS-iDTI and SS-iDTI) in 22 adults undergoing intraaxial iMRI resections (low-grade glioma: 14, 64%; high-grade glioma: 7, 32%; cortical dysplasia: 1). Regional susceptibility artifact, anatomical deviation relative to T1WI, and tractographic output were compared between iDTI sequences. Results: RS-iDTI resulted in less regional susceptibility artifact and mean anatomic deviation (RS-iDTI: 2.7±0.2 mm versus SS-iDTI 7.5±0.4 mm; p<0.0001). Tractographic failure occurred in 8/22 (36%) patients for SS-iDTI whereas RS-iDTI permitted successful reconstruction in 4 of these 8. Maximal tractographic differences between DTI sequences were substantial (mean 9.7±5.7 mm). Conclusions: Readout-segmented EPI enables higher quality and more accurate DTI for surgically relevant tractography of major white matter tracts in intraoperative, open cranium, neurosurgical applications at 3T.

A Simplified Method of Accurate Postprocessing of Diffusion Tensor Imaging for Use in Brain Tumor Resection

2015 ◽  
Vol 13 (1) ◽  
pp. 47-59 ◽  
Author(s):  
Phillip A. Bonney ◽  
Andrew K. Conner ◽  
Lillian B. Boettcher ◽  
Ahmed A. Cheema ◽  
Chad A. Glenn ◽  
...  
Keyword(s):  
Brain Tumor ◽  
Diffusion Tensor Imaging ◽  
Diffusion Tensor ◽  
Tumor Resection ◽  
Low Grade ◽  
Perceived Difficulty ◽  
Intracranial Lesions ◽  
Brain Tumor Resection ◽  
Frontal Lesions ◽  
Diffusion Tensor Imaging Dti

Abstract BACKGROUND: Use of diffusion tensor imaging (DTI) in brain tumor resection has been limited in part by a perceived difficulty in implementing the techniques into neurosurgical practice. OBJECTIVE: To demonstrate a simple DTI postprocessing method performed without a neuroscientist and to share results in preserving patient function while aggressively resecting tumors. METHODS: DTI data are obtained in all patients with tumors located within presumed eloquent cortices. Relevant white matter tracts are mapped and integrated with neuronavigation by a nonexpert in < 20 minutes. We report operative results in 43 consecutive awake craniotomy patients from January 2014 to December 2014 undergoing resection of intracranial lesions. We compare DTI-expected findings with stimulation mapping results for the corticospinal tract, superior longitudinal fasciculus, and inferior fronto-occipital fasciculus. RESULTS: Twenty-eight patients (65%) underwent surgery for high-grade gliomas and 11 patients (26%) for low-grade gliomas. Seventeen patients had posterior temporal lesions; 10 had posterior frontal lesions; 8 had parietal-temporal-occipital junction lesions; and 8 had insular lesions. With DTI-defined tracts used as a guide, a combined 65 positive maps and 60 negative maps were found via stimulation mapping. Overall sensitivity and specificity of DTI were 98% and 95%, respectively. Permanent speech worsening occurred in 1 patient (2%), and permanent weakness occurred in 3 patients (7%). Greater than 90% resection was achieved in 32 cases (74%). CONCLUSION: Accurate DTI is easily obtained, postprocessed, and implemented into neuronavigation within routine neurosurgical workflow. This information aids in resecting tumors while preserving eloquent cortices and subcortical networks.

scholarly journals What does the water inside the brain tell us? Diffusion tensor imaging

2018 ◽  
Vol 2 (4) ◽  
pp. 177-179
Author(s):  
Niyazi Acer ◽  
Mehmet Sait Dundar ◽  
Serap Bastepe-Gray
Keyword(s):  
Diffusion Tensor Imaging ◽  
White Matter ◽  
Cerebral Ischemia ◽  
Metabolic Disorders ◽  
Diffusion Tensor ◽  
Neurological Diseases ◽  
White Matter Lesions ◽  
The Brain ◽  
Diffusion Tensor Imaging Dti ◽  
Degenerating Axons

Abstract The brain consist of about 75 percent water. Diffusion tensor imaging (DTI) is an advanced magnetic resonance (MR) technique imaging that has been developed for diagnostic and research in medicine. It can be use DTI tractography to better understand degenerating axons of white matter lesions in some neurological diseases such as MS, AD, trauma, cerebral ischemia, epilepsy, brain tumors and metabolic disorders.

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