scholarly journals Development of a bioactive implant for repair and potential healing of cranial defects

2014 ◽  
Vol 120 (1) ◽  
pp. 273-277 ◽  
Author(s):  
Thomas Engstrand ◽  
Lars Kihlström ◽  
Erik Neovius ◽  
Ann-Charlott Docherty Skogh ◽  
T. Kalle Lundgren ◽  
...  
Keyword(s):  
Bone Healing ◽  
Bone Ingrowth ◽  
Clinical Results ◽  
Cranial Bone ◽  
Reconstruction Method ◽  
Ceramic Tiles ◽  
Cranial Defect ◽  
Cranial Implant ◽  
Soft Tissue Covering

The repair of complex craniofacial bone defects is challenging and a successful result is dependent on the size of the defect, quality of the soft tissue covering the defect, and choice of reconstruction method. The objective of this study was to develop a bioactive cranial implant that could provide a permanent reconstructive solution to the patient by stimulating bone healing of the defect. In this paper the authors report on the feasibility and clinical results of using such a newly developed device for the repair of a large traumatic and therapy-resistant cranial bone defect. The patient had undergone numerous attempts at repair, in which established methods had been tried without success. A mosaic-designed device was manufactured and implanted, comprising interconnected ceramic tiles with a defined calcium phosphate composition. The clinical outcome 30 months after surgery revealed a restored cranial vault without postoperative complications. Computed tomography demonstrated signs of bone ingrowth. Examination with combined 18F-fluoride PET and CT provided further evidence of bone healing of the cranial defect.

Different Types of Auricular Keloids and Treatment by Intralesional Cryosurgery: Best Practice for Obtaining Long-Lasting Clinical Results

Dermatology ◽  
2021 ◽  
pp. 1-10
Author(s):  
Yaron Har-Shai ◽  
Lior Har-Shai ◽  
Viktor A. Zouboulis ◽  
Christos C. Zouboulis
Keyword(s):  
Quality Of Life ◽  
Body Image ◽  
Recurrence Rate ◽  
Best Practice ◽  
Clinical Results ◽  
Psychosocial Impact ◽  
Aesthetic Outcome ◽  
The Past ◽  
Different Types

<b><i>Background:</i></b> Auricular keloids belong to the most perplexing medical conditions, which have significant psychosocial impact on the patient’s body image and quality of life. <b><i>Summary:</i></b> The article is purposed to provide dermatologists and plastic surgeons with the best proven practice using intralesional cryosurgery for the treatment of the different auricular keloid types in order to obtain superior clinical results by minimizing the probability of recurrence. In the past 20 years, the authors have developed novel procedures in order to increase the effectiveness of intralesional cryosurgery on auricular keloids, including hydrodissection, warm gauze technique, and excision of dangling skin. Long-lasting clinical results with a low recurrence rate and a satisfactory aesthetic outcome are achieved with no deformation of the ear framework.

scholarly journals Novel Reconstruction Using Roux-en-Y Plus Antral Obstruction Following Proximal Gastrectomy: Feasibility and Quality of Life Benefits

2019 ◽  
Author(s):  
Dejun Yang ◽  
Changming Wang ◽  
Hongbing Fu ◽  
Ziran Wei ◽  
Xin Zhang ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Reflux Esophagitis ◽  
Proximal Gastrectomy ◽  
Partial Gastrectomy ◽  
Incidence Rates ◽  
Reconstruction Method ◽  
Reflux Symptoms ◽  
Reconstruction Methods ◽  
Postoperative Reflux

Abstract Background and Aims Routine gastroesophagostomy has been shown to have adverse effects on the recovery of digestive functions and quality of life because patients typically experience reflux symptoms after proximal gastrectomy. This study was performed to assess the feasibility and quality of life benefits of a novel reconstruction method termed Roux-en-Y anastomosis plus antral obstruction (RYAO) following proximal partial gastrectomy. Methods A total of 73 patients who underwent proximal gastrectomy from June 2015 to June 2017 were divided into two groups according to digestive reconstruction methods [RYAO (37 patients) and conventional esophagogastric anastomosis with pyloroplasty (EGPP, 36 patients)]. Clinical data were compared between the two groups retrospectively. Results The mean operative time for digestive reconstruction was slightly longer in the RYAO group than in the EGPP group. However, the incidence of postoperative short-term complications did not differ between the RYAO and the EGPP groups. At the 6-month follow-up, the incidence rates of both reflux esophagitis and gastritis were lower in the RYAO group than in the EGPP group (P = 0.002). Additionally, body weight recovery was better in the RYAO group (P = 0.028). The scale tests indicated that compared with the patients in the EGPP group, the patients in the RYAO group had significantly reduced reflux, nausea and vomiting and reported improvements in their overall health status and quality of life (all P < 0.05). Conclusion RYAO reconstruction may be a feasible procedure to reduce postoperative reflux symptoms and the incidence of reflux esophagitis and gastritis, thus improving patient quality of life after proximal gastrectomy.

scholarly journals Experimental study of cooling tower performance using ceramic tile packing

2013 ◽  
Vol 7 (1) ◽  
pp. 21-27 ◽  
Author(s):  
Ramkumar Ramkrishnan ◽  
Ragupathy Arumugam
Keyword(s):  
Experimental Study ◽  
Cooling Tower ◽  
Packing Material ◽  
Transfer Coefficients ◽  
Ceramic Tiles ◽  
Burnt Clay ◽  
Different Types ◽  
Roofing Material ◽  
Forced Draft

Deterioration of the packing material is a major problem in cooling towers. In this experimental study ceramic tiles were used as a packing material. The packing material is a long life burnt clay, which is normally used as a roofing material. It prevents a common problem of the cooling tower resulting from corrosion and water quality of the tower. In this study, we investigate the use of three different types of ceramic packings and evaluate their heat and mass transfer coefficients. A simple comparison of packing behaviour is performed with all three types of packing materials. The experimental study was conducted in a forced draft cooling tower. The variations in many variables, which affect the tower efficiency, are described.

A Review on Chemical Synthesis and Density Enhancement in HAp / TiO2 Implants

2021 ◽  
Vol 9 (9) ◽  
pp. 1571-1577
Author(s):  
Puja Bhagabati
Keyword(s):  
Clinical Results ◽  
Biologically Active ◽  
Coating Materials ◽  
Bioactive Coatings ◽  
Steady Growth ◽  
Chemical Inertness ◽  
Low Toxicity ◽  
Differentiation And Proliferation ◽  
Single Size

Abstract: Owing to the excellent mechanical properties , good strength , low density and low toxicity in body fluid, most implants used are based on titanium and its alloys. They don't really, though, have high conductivity and osteo-integration. When using biocompatible and bioactive coatings, the compatibility and bioactivity of the implant material can be boosted. HAp, which is commonly evaluated for its chemical inertness and osteoinduction, is among the most used coating materials that meet the above requirements. For good clinical results, significant scientific findings, and a clear regulatory pathway, research and development of porous structures continues. Although not all applications suit a single size distribution or patterned structure, the majority of porous and textured biomaterials used in medical devices share the common feature of interlinking spaces that facilitate the transfer of nutrients and facilitate the differentiation and proliferation of cells.Safe graft interaction with the surrounding host cell decreases micromotion-induced inflammation and supports steady growth of fibrous content that facilitates healing and reduces disease. So far, many porogenous materials such as napthelene and camphor have been used to establish porosity. When exposed to high temperature, these porogenes will escape from the material that causes Inter communication pores in the material. Hydroxyapatite ( HAp) belongs to a biologically active moving charges which provides a solid link with the tissues of the surrounding body. One of this material 's drawbacks is that it has lower strength. Titanium oxide (TiO2) is a metal that belongs to the reinforcing agents material class and does not respond to the tissue surrounding it.TiO2's tensile characteristics is usually high and, as an implant unit, can be a good replacement. Efforts have been made to make a combination with better surface quality of both HAp / TiO2 biomaterial device and porosity HAp is commonly used as an implant for the reconstruction of bones, as a covering for metal substrates and as a drug-controlled release. Keywords: Hydroxyapatite, Biocompatibility, Bioactive, Bioinert, Porosity

Well-being of North Eastern Migrant Workers in Bangalore

2020 ◽  
Vol 14 (1) ◽  
pp. 99-114
Author(s):  
Divya Pradeep ◽  
K. C. Adaina ◽  
Sonia Kahmei
Keyword(s):  
Quality Of Life ◽  
Migrant Workers ◽  
Positive Emotions ◽  
Negative Emotions ◽  
Well Being ◽  
Reconstruction Method ◽  
Subjective Well Being ◽  
North East ◽  
Material Conditions

This paper explores the quality of life and subjective well-being of north-east migrant workers engaged in various formal and informal jobs in Bangalore. The composite well-being index reveals moderate well-being for the majority of workers. The disaggregated analysis, however, shows poor material conditions of life. Using the Day Reconstruction Method, we also find positive emotions associated with activities such as socialising but negative emotions for work and commuting. With respect to interacting partners, the negative emotions were highest while dealing with clients and customers. We also found positive correlations between life satisfaction and quality of life indicators, most strongly, with job quality. Lower quality of jobs, reported by women in comparison to men, suggests that organisations should aim to create more equal and enabling work spaces for all genders.

Quality of life and clinical results after endovascular sclerotherapy: A comparison between intra- and extramuscular low-flow venous malformations

2020 ◽  
pp. 026835552096292
Author(s):  
Annamaria Weitz-Tuoretmaa ◽  
Leo Keski-Nisula ◽  
Riitta Rautio ◽  
Jussi Laranne
Keyword(s):  
Quality Of Life ◽  
Clinical Results ◽  
Post Treatment ◽  
Low Flow ◽  
Subjective Symptoms ◽  
Venous Malformations ◽  
University Hospitals ◽  
Mri Findings ◽  
Mri Scans

Background Based on clinical observations we hypothesized that patients with intramuscular venous malformations (VMs) did worse or needed more sclerotherapy sessions than patients with extramuscular VMs. Purpose To evaluate the difference in treatment and quality of life (QOL) results after Polidocanol sclerotherapy of intra- and extramuscular low-flow VMs. Material and methods Forty-one patients with a VM were treated with Polidocanol in two university hospitals. The results were retrospectively analyzed. Pre- and post-treatment magnetic resonance imaging (MRI) scans were compared. All patients completed a self-evaluating form on symptoms as well as a QOL questionnaire. The results were compared between two groups: intra- and extramuscular VM’s. Results No statistically significant differences between intra- and extramuscular groups concerning QOL and specific dimensions pain, functional problems or cosmetic appearance were found. Radiological changes in MRI examinations did not correlate with any of the subjective symptoms. 56% of the patients benefitted from the treatment according to patient self-evaluation. Conclusion In this material intramuscular VM’s responded to the treatment comparably to extramuscular malformations. Post-treatment MRI findings do not correlate with subjective symptoms or QOL results and thus, a routine post-treatment examination seems to be unwarranted. Subjective symptoms and QOL results are the most important parameters in evaluating the effectiveness of sclerotherapy.

scholarly journals Compressive Stockings After Hindfoot and Ankle Surgery

2018 ◽  
Vol 3 (3) ◽  
pp. 2473011418S0023
Author(s):  
Florian Grubhofer ◽  
Stephan Wirth
Keyword(s):  
Quality Of Life ◽  
Clinical Results ◽  
Control Group ◽  
End Points ◽  
High Compliance ◽  
Group I ◽  
Sf 36 ◽  
Ankle Surgery ◽  
Group Ii

Category: Hindfoot Introduction/Purpose: Swelling and pain are common after foot and ankle procedures. We hypothesized that compressive stockings (CS) treatment after hindfoot surgery would positively influence patient outcomes. Methods: We undertook this randomized controlled trial in 87 consecutive patients to analyze the clinical effect of CS after hindfoot and ankle surgery and evaluate CS-wearing compliance using sensors that were implanted into CS. Ankle swelling, pain status, quality of life (SF-36 score), and the American Orthopaedic Foot & Ankle Score (AOFAS) were set as the primary end points. The CS wearing time in hours and percentage were investigated as the secondary end points. All participants with CS (group I) were informed about the implanted sensor after the CS were taken off. A subgroup analysis of group I was performed to detect differences between patients with high vs low compliance. Results: At 12 weeks, the results of ankle swelling (mean 234 mm in group I and 232 mm in group II), pain in the visual analog scale (1.7 group I vs 1.9 in group II), the SF-36 score (38 points in group I vs 30 points in group II), and the AOFAS score (a mean of 76 points in both groups) showed no statistical differences between the 2 groups. The mean wearing time was 136 (range, 0-470) hours, which corresponds to a compliance rate of 65%. Sixteen participants had high compliance (>80%, >170 hours), and 21 patients had low or noncompliance. The clinical results of patients with high wearing compliance were not significantly better compared to the results of patients with low compliance. Conclusion: CS therapy after ankle and hindfoot surgery was associated with a low wearing compliance and did not influence ankle swelling, function, pain, and the quality of life compared to the control group. Furthermore, the clinical results of patients with high compliance were not better compared to the results of patients with low or noncompliance wearing behavior.

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