A Review on Chemical Synthesis and Density Enhancement in HAp / TiO2 Implants

2021 ◽  
Vol 9 (9) ◽  
pp. 1571-1577
Author(s):  
Puja Bhagabati
Keyword(s):  
Clinical Results ◽  
Biologically Active ◽  
Coating Materials ◽  
Bioactive Coatings ◽  
Steady Growth ◽  
Chemical Inertness ◽  
Low Toxicity ◽  
Differentiation And Proliferation ◽  
Single Size

Abstract: Owing to the excellent mechanical properties , good strength , low density and low toxicity in body fluid, most implants used are based on titanium and its alloys. They don't really, though, have high conductivity and osteo-integration. When using biocompatible and bioactive coatings, the compatibility and bioactivity of the implant material can be boosted. HAp, which is commonly evaluated for its chemical inertness and osteoinduction, is among the most used coating materials that meet the above requirements. For good clinical results, significant scientific findings, and a clear regulatory pathway, research and development of porous structures continues. Although not all applications suit a single size distribution or patterned structure, the majority of porous and textured biomaterials used in medical devices share the common feature of interlinking spaces that facilitate the transfer of nutrients and facilitate the differentiation and proliferation of cells.Safe graft interaction with the surrounding host cell decreases micromotion-induced inflammation and supports steady growth of fibrous content that facilitates healing and reduces disease. So far, many porogenous materials such as napthelene and camphor have been used to establish porosity. When exposed to high temperature, these porogenes will escape from the material that causes Inter communication pores in the material. Hydroxyapatite ( HAp) belongs to a biologically active moving charges which provides a solid link with the tissues of the surrounding body. One of this material 's drawbacks is that it has lower strength. Titanium oxide (TiO2) is a metal that belongs to the reinforcing agents material class and does not respond to the tissue surrounding it.TiO2's tensile characteristics is usually high and, as an implant unit, can be a good replacement. Efforts have been made to make a combination with better surface quality of both HAp / TiO2 biomaterial device and porosity HAp is commonly used as an implant for the reconstruction of bones, as a covering for metal substrates and as a drug-controlled release. Keywords: Hydroxyapatite, Biocompatibility, Bioactive, Bioinert, Porosity

Семенная продуктивность свеклы: влияние биологически активных препаратов

2018 ◽  
Author(s):  
L.A. Yusupova
Keyword(s):  
Biologically Active ◽  
Single Plant ◽  
Vegetative Part ◽  
Red Beet

Приведены результаты влияния биологически активных препаратов (БАП) на продуктивность семенного куста раздельноплодной (одно-двусемянной) свеклы столовой сорта Хуторянка. Обработка растений БАП повлияла на формирование надземной вегетативной части растений и на качество семян свеклы столовой, а также позволила повысить выход семян с одного растения и улучшить качество семян.The results of the influence of biologically active preparations on (BAP) the productivity of the seed bush of a single-seeded (one-seeded) red beet of Khutorianka cultivar are given. The treatment of plants of the BAP influenced the formation of the aboveground vegetative part of plants and the quality of beet seed, and also increased the yield of seeds from a single plant and improved the quality of seeds.

Productivity and technological qualities of pork when using biological drugs

2020 ◽  
pp. 12-28
Author(s):  
O. Mikheeva ◽  
V. Fedyuk ◽  
M. Slozhenkina
Keyword(s):  
Endocrine Cells ◽  
Intestinal Microflora ◽  
Biologically Active ◽  
Large White ◽  
Biological Drugs ◽  
Animal Blood ◽  
Intestinal Microbiology ◽  
White Breed ◽  
Meat Productivity

In world practice biologically active drugs are widely used at different technological stages of rearing pigs, poultry and cattle. Special attention should be paid to bio-grugs obtained not as a result of chemical synthesis, but isolated from organs and tissues of healthy animals. Restoration of normal intestinal microflora of the animal is the basis of the concept of probiotics. Currently, probiotics are considered as endogenous intestinal microflora most often belonging to the group of lactobacilli, streptococci or bifidobacteria or as specific growth factors for them. Probiotics are selected according to certain criteria based on scientific knowledge of the physiology of intestinal microbiology, as well as animal nutrition. The purpose of the work was to study the effect of biological products on resistance, reproductive, fattening and meat productivity of pigs, on the quality of whole-muscle and fine-structured pork products; to develop a method of application of duodenum extract in combination with probiotics to increase the productivity of pigs. Studies on the effect of extracts derived from endocrine cells of the intestine, in combination with probiotics on the productivity of pigs of Large White breed and the quality of pork, as well as studied the effect of duodenins and probiotics in different concentrations on the protective properties of animal blood have been carried out. New methods of application of extracts of endocrine cells of intestines and probiotics for increase of meat productivity of animals and quality of pork have been offered. The use of bio-drugs increased the livability of young animals in all experimental groups from 1st to 4st by 3,51; 6,05; 4,95 and 5,90 %, respectively. There was an advantage in the amount of revenue from the sale of products of all experimental groups over the control one.

Different Types of Auricular Keloids and Treatment by Intralesional Cryosurgery: Best Practice for Obtaining Long-Lasting Clinical Results

Dermatology ◽  
2021 ◽  
pp. 1-10
Author(s):  
Yaron Har-Shai ◽  
Lior Har-Shai ◽  
Viktor A. Zouboulis ◽  
Christos C. Zouboulis
Keyword(s):  
Quality Of Life ◽  
Body Image ◽  
Recurrence Rate ◽  
Best Practice ◽  
Clinical Results ◽  
Psychosocial Impact ◽  
Aesthetic Outcome ◽  
The Past ◽  
Different Types

<b><i>Background:</i></b> Auricular keloids belong to the most perplexing medical conditions, which have significant psychosocial impact on the patient’s body image and quality of life. <b><i>Summary:</i></b> The article is purposed to provide dermatologists and plastic surgeons with the best proven practice using intralesional cryosurgery for the treatment of the different auricular keloid types in order to obtain superior clinical results by minimizing the probability of recurrence. In the past 20 years, the authors have developed novel procedures in order to increase the effectiveness of intralesional cryosurgery on auricular keloids, including hydrodissection, warm gauze technique, and excision of dangling skin. Long-lasting clinical results with a low recurrence rate and a satisfactory aesthetic outcome are achieved with no deformation of the ear framework.

CONSUMER PROPERTIES OF PASTA WITH POWDER FROM MARIGOLD INFLORESCENCES (TAGETES L.)

2021 ◽  
Vol 40 (4) ◽  
pp. 102-112
Author(s):  
SHAPOVALOVA Nataliia ◽  
VEZHLIVTSEVA Svitlana ◽  
ANTIUSHKO Dmytro
Keyword(s):  
Raw Materials ◽  
Experimental Studies ◽  
The Body ◽  
Biologically Active Substances ◽  
Biologically Active ◽  
Organoleptic Properties ◽  
Biological Value ◽  
Plant Raw Materials ◽  
Active Substances

Background. The deficiency of essential nutrients in the human body is the root cause of reduced efficiency, general resistance of the body to various diseases. That is an urgent problem in the context of the spread of coronavirus infection. In this regard, the search for opportunities to meet the needs of the population in food products that contain biologically active substances (BAS) through the use of high-value and at the same time available plant raw materials is extremely important. Marigolds attract special attention among such raw materials. The aim of the work is to study the chemical composition and evaluate the consumer properties of Tagetes L. varieties, zoned in the Kiev region, to prove the possibility of increasing the biological value of pasta by adding to their recipe powder from marigold inflorescences. Materials and methods. The object of research is pasta of B group (noodles). Inflorescences of marigolds of different varieties gathered during the flowering period in July-September 2019–2020 in the territory of Vasylkiv and Obukhiv districts of Kyiv region, Ukraine were used as enriching plant raw materials. The quality of finished pasta was assessed by organoleptic and physicochemical indexes (moisture content and titratable acidity). The content of mineral elements in the fine powder of marigold inflorescences was determined on the EXHERT-3L device, the quantitative composition and BAS identification – by spectrophotometric analysis on the device Specord-200 Analytic Jena UV-vis. The integrated quality index of pasta products was calculated taking into account the importance factors of individual indexes. Results. Comparing the obtained results, we can state that all the studied varieties – Gold Kopfen, Orange Flame, Hawaii, Equinox are characterized by high biological value, regardless of the area of collection. As a result of calculated and experimental studies it was determined that the addition of 7 % of the supplement does not provide the required supply of vitamins and minerals. Replacing the flour in the recipe by 20 % significantly improves the mineral composition, but deteriorates the taste and aromatic properties of pasta. The most optimal and rational amount of added additive is 15 %, as it improves the organoleptic properties of pasta and enriches their BAS. Conclusion. The usage of non-traditional vegetable raw materials, in particular powder from marigold inflorescences, which is rich in biologically active substances, allows not only to expand the range, improve the quality of finished products, but also increase the biological value of the product. The optimal amount of additive –powder from marigold inflorescences, was defined. It is 15 % by weight of flour in the production of noodles. This concentration allows not only to improve the organoleptic properties, but also to increase the content of biologically active substances – vitamins, micro- and macronutrients. The usage of non-traditional natural raw materials (powder from marigold inflorescences) allows to abandon artificial colorsand give the finished pasta a pleasant colorand aroma.

scholarly journals Traditional Herbal Medicine: A Review of Potential of Inhibitory Hepatocellular Carcinoma in Basic Research and Clinical Trial

2013 ◽  
Vol 2013 ◽  
pp. 1-7 ◽  
Author(s):  
Zhidong Wang ◽  
Jun Li ◽  
Yuanyuan Ji ◽  
Peng An ◽  
Shu Zhang ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Herbal Medicine ◽  
Herbal Remedy ◽  
Low Cost ◽  
Basic Research ◽  
Traditional Herbal Medicine ◽  
Aggressive Cancer ◽  
Low Toxicity ◽  
Arterial Chemoembolization

Although significantly develops in hepatocellular carcinoma (HCC), features of HCC remain an aggressive cancer with a dismal outcome. Traditional Chinese medicine (TCM), specifically Chinese herbal medicine (CHM), is one of the most popular complementary and alternative medicine modalities worldwide. The use of heat-clearing and detoxicating (Chinese namedqingre jiedu) CHM has attracted great attention as an alternative antitumor including HCC considering its low toxicity and high activity. Together these reports indicate that CHM is a promising anti-HCC herbal remedy in basic research. For patients with advanced HCC, CHM including formula and single combined with transcatheter arterial chemoembolization or chemotherapy is able to decrease tumor growth and the side effect of toxicity and improve overall survival, quality of life, and immune function. Due to its abundance, low cost, and safety in consumption, CHM remains a species with tremendous potential for further investigation in HCC.

scholarly journals Improvement of the cucumber protection system in the greenhouse for production environmentally safe products

2020 ◽  
pp. 15-20
Author(s):  
Svetlana Aleksandrovna Dudnikova ◽  
Valentina Vasilievna Lapina ◽  
Nikolay Vasilievich Smolin ◽  
Dmitry Vladimirovich Bochkarev
Keyword(s):  
Biologically Active ◽  
Net Income ◽  
Biological Products ◽  
Yield And Quality ◽  
Combined Use ◽  
Environmentally Safe ◽  
Beginning Of Flowering ◽  
Growth Development ◽  
Active Substances

Production of environmentally friendly cucumber products is one of the important problems of modern vegetable growing. In the current situation, many issues of cucumber technology using the low-volume technology method require adjustment and further improvement. The purpose of the research was to study and assess the effect of combinations of zircon with biofertilizers against the background of the use of biological products on the growth, development, yield and quality of cucumber. The complex treatment of cucumber plants of the F1 Atlet hybrid with biologically active substances (BAS) contributed to an increase in biometric indicators in comparison with the control throughout the entire crop rotation. The period from germination to the beginning of flowering and fruiting decreased, the plant height increased by 7.2–13.2% and the stem diameter by 12.5–17.5%. The yield was significantly influenced by the growth of the leaf area of cucumber plants, which increased in variants with experimental technologies by 5.9–34%. Under the influence of the studied factors, the yield of standard cucumber production increased by 8.0–27.6%. The mass fraction of fruits that do not meet the requirements of the standard was 6.6–8.1%. On the control variant, the output of non-standard products increased to 10%. The highest net income and level of profitability were obtained with the combined use of Zircon with Ecofus, both against the background of the use of biological products (659.3 rubles / m2 or 38.4%) and without them (685.13 rubles / m2 or 40.1%).

scholarly journals Effectiveness of pharmacopuncture by “alloplant” biomaterial in complex therapy of knee joint osteoarthritis

2020 ◽  
Vol 19 (1) ◽  
pp. 45-49
Author(s):  
Ruslan K. Urazbakhtin ◽  
Raushaniya N. Kildebekova ◽  
Lira T. Gilmutdinova ◽  
Vadim T. Kaybyshev ◽  
Ravil Sh. Mirkhaydarov ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Drug Therapy ◽  
Knee Joint ◽  
Well Being ◽  
Biologically Active ◽  
Basic Drug ◽  
Group Iii ◽  
Group I ◽  
Immunological Mechanisms

Background. Osteoarthritis is characterized by a decrease in the quality of life, which is currently considered as the main measure of well-being of an individual and a criterion for the effectiveness of treatment and rehabilitation measures. Modern research emphasizes the need for an integrated approach to the treatment of osteoarthritis, which should include pharmacological and non-drug methods of treatment. Aim. The purpose of the study was to evaluate the effectiveness of pharmacopuncture administration of Alloplant biomaterial by patients with osteoarthritis of the knee joint from the standpoint of influencing the immunological mechanisms of the disease. Methods. The randomization methodology was divided into 3 groups, comparable in terms of clinical and functional characteristics. Group I patients (n = 39) have standard basic drug therapy according to the federal clinical guidelines Osteoarthritis approved by the Association of Rheumatologists of Russia (2013), with additions from 2016; in patients of group II (n = 39), in addition to drug therapy, dispersed Alloplant biomaterial was used according to the original method; group III patients (n = 39) against the background of basic drug therapy are additionally prescribed a combination of dispersed Alloplant biomaterial at biologically active points and magnetic therapy with a pulsed magnetic field. Results. Against the background of the treatment of patients with osteoarthritis using pharmacopuncture with Alloplant biomaterial and magnetotherapy, there was a positive dynamics in clinical data with a significant decrease in pain intensity when walking and at rest, stiffness, with the restoration of immune status parameters and an improvement in the quality of life in the field of physical and psychological health . A more pronounced and lasting positive dynamics was observed in patients of group III against the background of the combined effects of pharmacopuncture with Alloplant biomaterial and magnetotherapy. Conclusion. The Alloplant biomaterial has a positive effect in the treatment of patients with stage III osteoarthritis according to the KellgrenLawrens classification. The similarity of the mechanism of action with drugs with a structurally modifying effect on cartilage allows us to recommend pharmacopuncture with Alloplant biomaterial for widespread use in the treatment of osteoarthritis.

scholarly journals Effect of enzyme preparation Ceramics 6XMG on indicators of oat malt quality

2018 ◽  
Vol 80 (3) ◽  
pp. 128-133
Author(s):  
G. V. Agafonov ◽  
A. E. Chusova ◽  
A. V. Zelenkova ◽  
V. E. Plotnikov
Keyword(s):  
Enzyme Preparation ◽  
Colorimetric Method ◽  
Biologically Active ◽  
Complex Action ◽  
Drying Time ◽  
Pronounced Increase ◽  
Enzyme Preparations ◽  
Organoleptic Characteristics ◽  
Object Of Study

One of the effective ways to increase the malt capacity of existing plants is the use of complex enzyme preparations. The enzyme preparation of complex action, penetrating into the grain during soaking or germination, affect its powdery body, contributing to the loosening of the cell membranes and the endosperm itself, thereby accelerating the process of malting. A purpose of researches is development of technology of fermented oat malt with the use of enzyme drug Ceramics 6ХМG. This enzyme preparation with complex action, has ?-amylase, protease, ?-glucanase, pentosanase, cellulose activities. As the object of study was taken oats Kozyr’ variety. Amylolytic ability of malt was determined by colorimetric method, proteolytic-refractometric method (according to Petrov). It was established that as a result of the use of Ceremix 6XMG in an amount of 0.1–0.5 kg per ton of grain, a more pronounced increase in amylolytic and proteolytic ability compared to the control (without the use of an enzyme preparation) occurs at a dosage of 0.5 kg per ton of grain. It is impractical to introduce Ceremix 6HMG in the amount of 0.5 kg per ton of grain, because the enzymatic activity of oat malt is only 6.4–6.6% higher than that of malt treated with an enzyme preparation in the amount of 0.3 kg per ton of grain. It was found that the use of the enzyme preparation Ceremix 6HMG allows to improve the quality of oat malt by improving organoleptic characteristics, increasing the mass fraction of extractives, as well as to intensify the process by reducing the drying time by 10-12 hours, which is important for the preservation of biologically active substances and energy resources.

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