scholarly journals The early argument for prefrontal leucotomy: the collision of frontal lobe theory and psychosurgery at the 1935 International Neurological Congress in London

2017 ◽  
Vol 43 (3) ◽  
pp. E4 ◽  
Author(s):  
Lillian B. Boettcher ◽  
Sarah T. Menacho
Keyword(s):  
Mental Illness ◽  
Frontal Lobe ◽  
Special Session ◽  
Early Argument ◽  
Cortical Localization ◽  
The 19Th Century ◽  
Modern Era ◽  
The Brain ◽  
Frontal Lobectomy ◽  
Frontal Ablation

The pathophysiology of mental illness and its relationship to the frontal lobe were subjects of immense interest in the latter half of the 19th century. Numerous studies emerged during this time on cortical localization and frontal lobe theory, drawing upon various ideas from neurology and psychiatry. Reflecting the intense interest in this region of the brain, the 1935 International Neurological Congress in London hosted a special session on the frontal lobe. Among other presentations, Yale physiologists John Fulton and Carlyle Jacobsen presented a study on frontal lobectomy in primates, and neurologist Richard Brickner presented a case of frontal ablation for olfactory meningioma performed by the Johns Hopkins neurosurgeon Walter Dandy. Both occurrences are said to have influenced Portuguese neurologist Egas Moniz (1874–1955) to commence performing leucotomies on patients beginning in late 1935. Here the authors review the relevant events related to frontal lobe theory leading up to the 1935 Neurological Congress as well as the extent of this meeting’s role in the genesis of the modern era of psychosurgery.

scholarly journals You Can Observe a Lot by Watching: Hughlings Jackson’s Underappreciated and Prescient Ideas about Brain Control of Movement

2018 ◽  
Vol 24 (5) ◽  
pp. 448-455
Author(s):  
Ari Berkowitz
Keyword(s):  
Frontal Lobe ◽  
19Th Century ◽  
Brain Regions ◽  
Body Parts ◽  
Seizure Focus ◽  
Somatotopic Organization ◽  
The 19Th Century ◽  
The Brain

John Hughlings Jackson, the 19th-century British neurologist, first described what are today called Jacksonian seizures. He is generally associated with somatotopy, the idea that neighboring brain regions control neighboring body parts, as later represented pictorially in Wilder Penfield’s “homunculus,” or little man in the brain. Jackson’s own views, however, were quite different, though this is seldom appreciated. In an 1870 article, Jackson advanced the hypotheses that each region of the cerebrum controls movements of multiple body parts, but to different degrees, and that the “march” of movements that typically occurs during Jacksonian seizures is caused by the downstream connections of the overactive neurons at the seizure focus, rather than a somatotopic organization of the cerebrum. Jackson’s hypotheses, which were based almost entirely on his careful observations of movements during seizures, are well within the range of current hypotheses about how the frontal lobe is organized to control movements and thus deserve renewed attention.

Relief of facial pain after combined removal of precentral and postcentral cortex

1971 ◽  
Vol 34 (4) ◽  
pp. 537-543 ◽  
Author(s):  
Richard A. Lende ◽  
Wolff M. Kirsch ◽  
Ralph Druckman
Keyword(s):  
Facial Pain ◽  
The Other ◽  
Precentral Gyrus ◽  
Nerve Section ◽  
Content Type ◽  
Burning Pain ◽  
Cortical Localization ◽  
The Brain ◽  
Fine Print ◽  
Frontal Lobotomy

✓ Cortical removals which included precentral and postcentral facial representations resulted in relief of facial pain in two patients. Because of known failures following only postcentral (SmI) ablations, these operations were designed to eliminate also the cutaneous afferent projection to the precentral gyrus (MsI) and the second somatic sensory area (SmII). In one case burning pain developed after a stroke involving the brain stem and was not improved by total fifth nerve section; prompt relief followed corticectomy and lasted until death from heart disease 20 months later. In the other case persistent steady pain that developed after fifth rhizotomy for trigeminal neuralgia proved refractory to frontal lobotomy; relief after corticectomy was immediate and has lasted 14 months. Cortical localization was established by stimulation under local anesthesia. Each removal extended up to the border of the arm representation and down to the upper border of the insula. Such a resection necessarily included SmII, and in one case responses presumably from SmII were obtained before removal. The suggestions of Biemond (1956) and Poggio and Mountcastle (1960) that SmII might be concerned with pain sensibility may be pertinent in these cases.

scholarly journals Meynert and the basal nucleus

2013 ◽  
Vol 7 (4) ◽  
pp. 435-438 ◽  
Author(s):  
Eliasz Engelhardt
Keyword(s):  
20Th Century ◽  
19Th Century ◽  
Basal Ganglion ◽  
Basal Nucleus ◽  
Cell Composition ◽  
Substantia Innominata ◽  
The 19Th Century ◽  
Considerable Body ◽  
The Brain

ABSTRACT Meynert described the "loop of the peduncular foot" (Schlinge des Hirnschenkelfusses), and its ganglion (Ganglion der Hirnschenkelschlinge) and related them to Reil's Substantia innominata and Gratiolet's Ansa peduncularis, from which he apparently built up his findings. Koelliker renamed the ganglion with the eponymous designation Meynert'sches Basalganglion (Meynert's basal ganglion), a name which endures to the present day, and described its topographical spread in relation to neighboring structures. Meynert and Koelliker also described aspects of cell composition of the ganglion (or nucleus) with a better account of the latter. Both, together with Reil and Gratiolet, were the outstanding personalities of the 19th century who performed the pioneering studies on basal formations of the forebrain. After these works, a considerable body of research appeared in the 20th century, with a focus on Meynert's basal nucleus and related structures. The development of further knowledge about these structures revealed their great importance in the activity of the brain, as evidenced in both normal and pathological states.

scholarly journals Topological Data Analysis reveals robust alterations in the whole-brain and frontal lobe functional connectomes in Attention-Deficit/Hyperactivity Disorder

2019 ◽  
Author(s):  
Zeus Gracia-Tabuenca ◽  
Juan Carlos Díaz-Patiño ◽  
Isaac Arelio ◽  
Sarael Alcauter
Keyword(s):  
Attention Deficit Hyperactivity Disorder ◽  
Data Analysis ◽  
Frontal Lobe ◽  
Attention Deficit ◽  
Brain Network ◽  
Topological Data Analysis ◽  
Hyperactivity Disorder ◽  
The Brain ◽  
Connectivity Threshold ◽  
Topological Data

AbstractThe functional organization of the brain network (connectome) has been widely studied as a graph; however, methodological issues may affect the results, such as the brain parcellation scheme or the selection of a proper threshold value. Instead of exploring the brain in terms of a static connectivity threshold, this work explores its algebraic topology as a function of the filtration value (i.e., the connectivity threshold), a process termed the Rips filtration in Topological Data Analysis. Specifically, we characterized the transition from all nodes being isolated to being connected into a single component as a function of the filtration value, in a public dataset of children with attention-deficit/hyperactivity disorder (ADHD) and typically developing children. Results were highly congruent when using four different brain segmentations (atlases), and exhibited significant differences for the brain topology of children with ADHD, both at the whole brain network and at the functional sub-network levels, particularly involving the frontal lobe and the default mode network. Therefore, this approach may contribute to identify the neurophysio-pathology of ADHD, reducing the bias of connectomics-related methods.HighlightsTopological Data Analysis was implemented in functional connectomes.Betti curves were assessed based on the area under the curve, slope and kurtosis.The explored variables were robust along four different brain atlases.ADHD showed lower areas, suggesting decreased functional segregation.Frontal and default mode networks showed the greatest differences between groups.Graphical Abstract

scholarly journals Critic on Auguste Comte’s Positivism in Sociology (An Islamic Sociology Perspective)

TRANSFORMATIF ◽  
2021 ◽  
Vol 4 (2) ◽  
pp. 211-221
Author(s):  
Novita Sari ◽  
Jarman Arroisi
Keyword(s):  
Descriptive Analysis ◽  
Point Of View ◽  
The Social ◽  
Auguste Comte ◽  
Three Stages ◽  
Fundamental Value ◽  
The Many ◽  
Research Types ◽  
The 19Th Century ◽  
Modern Era

The rapid science in the modern era, provides significant changes for humans, both in the fields of economics, politics, culture, environment, society, education, and even religion. The 19th century is a century of science that is growing rapidly, this can be seen from the emergence of various scientists who provide concepts, theories based on philosophy with basic ontology, epistemology, and axiology as a contribution to the development of science. One of them, the scientist known as the father of sociology, was Auguste Comte a scientist from France. Comte is famous for its philosophy of postivism because of the many references by scientists in the contemporary era. This is based on the calculation of the success of designing the social structure of modern humans with three stages of law, but one side of the theory he produced has eliminated the fundamental value in humans, namely eliminating the metaphysical basis. In a three-stage law, more concerned with physical values than metaphysical values, this will result in a society that abandons religion and even eliminates the existence of God. The thoughts produced by Comte are thoughts originating from the west, where the basic West is relativism so if viewed from an Islamic point of view this theory will produce atheists and eliminate the sanctity of religion. In Islam religion and society are inseparable because religion is a guideline that is used as a basis in people's lives based on the values of the Qur'an and Sunnah. Therefore in this paper we will study more deeply the criticisms of Aguste Comte's thinking, using qualitative research types, with descriptive analysis methods and theological philosophical approaches. 

PECULIARITIES OF THE ELITE SPORT POLITICIZATION PROCESS: HISTORICAL AND POLITICAL ANALYSIS

2021 ◽  
Vol 16 (5) ◽  
pp. 110-119
Author(s):  
E.V. SALNIKOV ◽  
◽  
I.N. SALNIKOVA ◽  
Keyword(s):  
19Th Century ◽  
21St Century ◽  
National State ◽  
Political Analysis ◽  
Norbert Elias ◽  
Political Interests ◽  
History Of ◽  
Competitive Games ◽  
The 19Th Century ◽  
Modern Era

The main purpose of the article is to reconstruct the history of sports politicization, by which the authors, in accordance with the position of Norbert Elias and Pierre Bourdieu, understand the special practice of competitive games that arises in the states of the modern era. In this sense, the beginning of modern sports is the second half of the 19th century. The article demonstrates that throughout its development, sport goes through a complex evolution from the form of the embodiment of the power of the national state to the concept of sports outside politics, which is currently collapsing under the influence of explicit and hidden practices of the repoliticization of sports. Special attention is paid to the history of the fight against racism in sports, which in the 21st century is becoming a space for the realization of political interests, the hidden form of which is the practices of the Black Lives Matter (BLM) movement.

Home Automation by Brain-Computer Interface

2014 ◽  
pp. 502-510
Author(s):  
Eduardo G. Nieva ◽  
María F. Peralta ◽  
Diego A. Beltramone
Keyword(s):  
Frontal Lobe ◽  
Brain Computer Interface ◽  
Heating System ◽  
Threshold Value ◽  
Threshold Level ◽  
Computer Interface ◽  
Second Step ◽  
Electroencephalographic Signals ◽  
Commercial Device ◽  
The Brain

In the present work, the authors use the Brain Computer Interface technology to allow the dependent persons the utilization of the basic elements of their house, such as turning on and turning off lamps, rolling up and down a roller shutter, or switching on the heating system. For doing this, it is necessary to automate these devices and to centralize its managing in a platform, which constitutes a domotics system. In order to achieve this, the authors have used the MindWave NeuroSky ® commercial device. It is affordable, portable, and wireless, and senses and delivers the computer the electroencephalographic signals produced in the frontal lobe and the levels of attention, relaxation, and blinking to the computer. In order to determine the efficiency of the obtained signals a test software was designed, which verified the operation´s device with different persons. The authors conclude that the easiest way to control the attention levels is concentrating on a certain point, and the way to control the relaxation levels is by closing the eyes. As a second step, the authors develop a software that takes the signal from the EEG (Electro Encephalo Graphy) sensor, processes it, and sends signals via USB to an Arduino board, which is associated with electronics that complies the different tasks. The user chooses the action by managing the attention levels. When they are higher than a particular threshold value, the action is executed. In order to disable this action, the user must lower the threshold level and overcome it again. This is the simplest and fastest way to handle, but it brings several problems: if the user concentrates for any other reason and this signal exceeds the threshold, it causes the activation of an involuntary action. To solve this problem, the authors use a three variables combination that can become independent of each other thru training properly. These variables are attention, meditation, and blink. When you comply with the three simultaneous previously established conditions, the action is executed, and when they return to fulfill the conditions, the action is deactivated. The software also has the feature of personalizing its conditions, so it can be best for any user, even a novice one.

An impairment in brain function

2021 ◽  
pp. 89-102
Author(s):  
Mark Selikowitz
Keyword(s):  
Executive Function ◽  
Frontal Lobe ◽  
Brain Function ◽  
Genetic Factors ◽  
Front Part ◽  
Behavioural Difficulties ◽  
Gene Defects ◽  
The Brain ◽  
Chemical Messengers ◽  
Executive Function Deficits

ADHD is usually due to a depletion of certain chemical messengers in the front part of the brain. The major cause of this depletion relates to a number of defective genes. ADHD shares some of its causative genes with certain other conditions, so having ADHD makes also having these other conditions more likely. To help many children with learning and behavioural difficulties, we need to treat an impairment in their brain function. This chapter discusses impairment in brain function as a cause of ADHD, including executive function deficits, frontal lobe underactivity, neurotransmitter depletion, gene defects, and non-genetic factors. It also describes the mechanism of comorbidity.

A historical perspective on neurological and neuropsychiatric definitions

2020 ◽  
pp. 3-8
Author(s):  
German E Berrios ◽  
Ivana S Marková
Keyword(s):  
Central Nervous System ◽  
Historical Perspective ◽  
Biological Psychiatry ◽  
Mental Symptom ◽  
Mental Diseases ◽  
Definition Of ◽  
The Uk ◽  
The 19Th Century ◽  
The Brain ◽  
Agreed Definition

Taking a historical epistemological perspective, this chapter explores how neurology and neuropsychiatry were constructed. As a medical specialism developing in the 19th century, neurology resulted from the convergence of: (1) the term ‘neurology’; (2) a set of concepts; and (3) a list of disorders. Such a convergence was facilitated by changes in the manner in which the concepts of neuroses, central nervous system, and lesion were to be defined after 1860. Neuropsychiatry carries a less stable epistemology. Underpinned by the foundational claim that mental diseases are diseases of the brain, its meaning has changed pari passu with redefinitions of the concepts such as mind, mental symptom, cause, and meaning. In the UK, there is no agreed definition of neuropsychiatry either and hence what is currently known as ‘organic/biological psychiatry’ and the claim that psychiatry is just a subregion of neurology cannot be considered as coterminous.

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