Effect of drugs on experimental brain edema in mice
1974 ◽
Vol 41
(2)
◽
pp. 193-199
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Keyword(s):
✓ Cold-induced hemorrhagic infarcts in mice caused a spreading decrease in tissue specific gravity around the lesion; the decrease in tissue density represents an increase in edema fluid. The maximum decrease in density in most brain areas had occurred by 6 hours. This time period was used to evaluate the effect of nine drugs on brain edema. Two agents increased edema formation: hexamethonium and meralluride. Metaraminol, cortisone, hydrocortisone, acetazolamide, and dextran did not significantly alter edema formation. Only in the phenoxybenzamine- and urea-treated mice was brain edema less than in the control mice.
2000 ◽
Vol 92
(6)
◽
pp. 1016-1022
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Keyword(s):
1971 ◽
Vol 34
(4)
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pp. 477-487
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Keyword(s):
2001 ◽
Vol 95
(4)
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pp. 680-686
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Keyword(s):
1978 ◽
Vol 49
(4)
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pp. 530-537
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Keyword(s):
1995 ◽
Vol 83
(6)
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pp. 1045-1050
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Keyword(s):
2004 ◽
Vol 100
(3)
◽
pp. 498-504
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Keyword(s):
1998 ◽
Vol 89
(6)
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pp. 991-996
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Keyword(s):
1996 ◽
Vol 85
(1)
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pp. 131-137
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Keyword(s):
1994 ◽
Vol 81
(1)
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pp. 93-102
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Keyword(s):