scholarly journals Prevalence of Dental Anomalies in the Patient with Cleft Lip and Palate Visiting a Tertiary Care Hospital

2020 ◽  
Vol 58 (228) ◽  
Author(s):  
Leeza Pradhan ◽  
Pramila Shakya ◽  
Swosti Thapa ◽  
Kiran Kishor Nakarmi ◽  
Anjana Maharjan ◽  
...  
Keyword(s):  
Cleft Lip ◽  
Cleft Lip And Palate ◽  
Demographic Data ◽  
Tertiary Care ◽  
Cross Sectional Study ◽  
Lateral Incisor ◽  
Care Hospital ◽  
Dental Anomalies ◽  
Cross Sectional ◽  
Institutional Review

Introduction: Dental anomaly is one of the major problems in a child born with cleft lip and palate. These anomalies have deleterious effects on the dentition leading to aesthetic problems, impairment of mastication andimproper phonation. The aim of our study was to find out the prevalence of dental anomalies in patient with cleft lip and/or palate radiographically. Methods: A descriptive cross-sectional study was conducted from the 208 radiographs, collected by the convenience samplingtechnique with cleft lip and/or palate in Department of Burns, Plastic and Reconstructive Surgery, Nepal Cleft and Burn Centre, Kirtipur Hospital from January 2017 to July 2019.Ethical clearance for the study was obtained from Institutional Review Committee. Demographic data were collected and radiographs were evaluated for possible dental anomalies. Data obtained were entered and analysed in Statistical Package for Social Sciences version 23. Results: Dental anomalies were highly prevalent among cleft lip and palate patients with at least one anomaly present in 188 (90.4%) of patients with male 120 (57.4%) presenting more anomalies than female 88 (42.6%) population. The most common anomaly was dental agenesis 161 (77.9%). The prevalence of positional anomaly, morphological anomaly and supernumerary teeth were found to be 54 (26%), 33 (15.9%) and 20 (10%) respectively. Lateral incisor showed the highest incidence of agenesis among all other missing teeth 223 (65.2%). Conclusions: The prevalence of dental anomalies among patients with cleft lip and/or palate was found to be high. Tooth agenesis was the most common anomaly observed in the study with lateral incisor having the highest incidence of agenesis.

scholarly journals Abnormal Fetal Echocardiography in Diabetic Pregnant Women at a Tertiary Care Hospital: A Descriptive Cross-sectional Study

2020 ◽  
Vol 58 (227) ◽  
Author(s):  
Jyotshna Sharma ◽  
Sanjeeb Tiwari
Keyword(s):  
Gestational Diabetes ◽  
Pregnant Women ◽  
Tertiary Care Hospital ◽  
Fetal Echocardiography ◽  
Tertiary Care ◽  
Cross Sectional Study ◽  
Care Hospital ◽  
Sectional Study ◽  
Cross Sectional ◽  
Institutional Review

Introduction: The sedentary lifestyle of women and change in their food habits has a significantrole in developing diabetes in pregnancies. This leads to an increased chance of fetal cardiacabnormality born by a mother with gestational diabetes and pre-existing diabetes. The objectiveof the study is to find out the prevalence of abnormal fetal echocardiography in gestational andpre-existing diabetic pregnant women at a tertiary care hospital. Methods: A descriptive cross-sectional study was conducted among 104 diabetic pregnantwomen in a tertiary care hospital from April 15, 2017, to April 14, 2018. Ethical approvalwas obtained from the institutional review committee. The convenient sampling method wasused. The patients who were diagnosed as gestational diabetes and diabetic before pregnancywere included in the study. Fetal echocardiography was mainly done at a gestational age of22-32 weeks depending upon the time of diagnosis of gestational diabetes and for pre-diabeticwomen, fetal echocardiography was done at 24-26 weeks of gestation. Statistical analysis wasdone using the Statistical Package of the Social Sciences version 20. Results: Among 104 patients, 16 (15.38%) patients had abnormal fetal echocardiography.Eighty-three (79.81%) were gestational diabetics, 21 (20.19%) were pre-existing diabeticwomen. Among 83 gestational diabetes, 7 (8.4%) had abnormal echo finding and among 21pre-existing diabetics, 9 (42.8%) had abnormal echo finding. Conclusions: There was an increased chance of fetal cardiac malformation in gestational diabeticand pre-existing diabetics diabetic especially in an uncontrolled glycemic state. And, if theywere diagnosed prenatally, clinical outcomes for both mother and fetus would have been better.

scholarly journals Histopathological Study of Post-Surgical Gallbladder to Establish True Histopathology Proven Chronic Inflammation

2021 ◽  
Vol 8 (3) ◽  
pp. 15-19
Author(s):  
Tania Khattak ◽  
Almas Khattak ◽  
Susan Kakakhel ◽  
Anwar Ul Haque
Keyword(s):  
Chronic Inflammation ◽  
Demographic Data ◽  
Descriptive Analysis ◽  
Tertiary Care ◽  
Cross Sectional Study ◽  
Chronic Cholecystitis ◽  
Histopathological Study ◽  
Care Hospital ◽  
Histopathological Changes ◽  
Cross Sectional

OBJECTIVES: The aim of this study was to establish true histopathology proven diagnosis of chronic cholecystitis. METHODOLOGY: A cross-sectional study was conducted on 51 post-surgical gallbladders was done to assess their histopathological patterns in a single centered tertiary care hospital. The specimens were studied for chronic cholecystitis, fibrosis, hypertrophy and presence of Rokitansky-Aschoff sinuses. Descriptive analysis was done and associations of the histopathological changes with demographic data of patients were analyzed through Chi-squared test. RESULTS: Fifty-one post cholecystectomy samples of gallbladder were analyzed for histopathological changes with 82.4% showing chronic cholecystitis, 84.3% fibrosis, 64.7% congestion, and more than 60% mild or moderate hypertrophy. Moreover, 49% of the specimens showed Rokitansky-Aschoff sinuses. All these changes suggest chronic inflammation. CONCLUSION: Chronic cholecystitis, fibrosis, and Rokitansky-Aschoff sinuses are the most common histopathological findings in specimens of patients undergone cholecystectomy for cholelithiasis.  

scholarly journals Prevalence of Community-Acquired Pyoderma in Dermatological Outpatient Department of A Tertiary Care Hospital

2019 ◽  
Vol 57 (217) ◽  
Author(s):  
Rupak Bishwokarma Ghimire ◽  
Khilasha Pokhrel ◽  
Sanjubabu Shrestha
Keyword(s):  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
College Teaching ◽  
Cross Sectional Study ◽  
Hair Follicles ◽  
Outpatient Department ◽  
Point Estimate ◽  
Care Hospital ◽  
Cross Sectional ◽  
Institutional Review

Introduction: Pyoderma is defined as any purulent skin disease and represents infections inepidermis and dermis or hair follicles. This study aims to find out the prevalence of communityacquired pyoderma in dermatological outpatient department of a tertiary care hospital. Methods: A descriptive cross-sectional study was carried out among patients who presented atdermatology outpatient department of Kathmandu Medical College Teaching Hospital betweenDecember 2018 and March 2019 after ethical clearance from institutional review committee.Convenience sampling method was done. Data was collected and analysis was done using SPSSsoftware, point estimate at 95% CI was calculated along with frequency and proportion for binarydata. Results: Out of 385 cases, 72 (18%) cases were of community-acquired pyoderma. Prevalence ofcommunity-acquired pyoderma is 72 (18%) at 95% CI(). Primary pyoderma was seen in 49 (12.72%)mainly folliculitis 17 (4.41%), furunculosis 16 (4.15%), impetigo 6 (1.55%), abscess 6 (1.55%) andbacterial paronychia 4 (1.03%). Staphylococcus aureus was the most common organism isolated in 42(58.3%) cases and Staphylococcus epidermidis was isolated in 3 (4.17%) cases. Staphylococcus aureuswas most sensitive to Vancomycin 42 (100%) followed by Gentamycin 40 (95.2%), Ciprofloxacin 40(95.2%) and Ceftriaxone 40 (95.2%). Highest resistance was seen to Azithromycin in 13 (30.95%),followed by Cloxacilllin in 11 (26.19%). Males were affected predominantly in 49 (68.06%) ascompared to females in 23 (31.94%). Conclusions: Prevalence of community-acquired pyoderma is high among patients visitingdermatological outpatient departments of a tertiary care hospital compared to other studies.Antibiotic resistance of commonly used antibiotics are increasing and thus proper cultureand sensitivity reports may be required to guide our treatment

scholarly journals Study of Parasitic Infection in Immunosuppressive Patients and its Association with the Socio-demographic Status

2021 ◽  
Author(s):  
J Lakhani Sucheta ◽  
Dhruba Hari Chandi ◽  
J Lakhani Som
Keyword(s):  
Entamoeba Histolytica ◽  
Close Contact ◽  
Demographic Data ◽  
Tertiary Care ◽  
Parasitic Infection ◽  
Cross Sectional Study ◽  
Parasitic Infections ◽  
P Value ◽  
Care Hospital ◽  
Cross Sectional

Introduction: In developing countries, immunosuppressive patients are at greater risk of parasitic infection which may cause morbidity and mortality. Socio-economic and environmental factors including lack of health hygiene in close contact with infected reservoir animal which plays an important role. Aim: To determine the prevalence of parasitic infections and their association with socio-demographic status. Materials and Methods: This was a cross-sectional study which was carried out at tertiary care hospital located in Central East India. Total 120 stool samples were collected from the immunosuppressive patients and were processed using direct wet mount preparation with saline and Lugol, formalin-ether concentration and Modified Ziehl-Neelsen stain. Different socio-demographic parameters were recorded. Statistical analysis was done using Graph Pad Prism version 8 Chi-square test. The p-value ≤0.05 was considered as statistically significant Results: Out of total 120 patients, 20 (16.7%) were found to be infected. Majority of the population were males (66.7%). Among the total positive samples, 75% (15) showed the presence of Protozoa in which 10 samples had Entamoeba histolytica. The presence of Helminths was found in 25% (5), in which three samples showed Ascaris lumbricoides and two had Taenia species (10%). Conclusion: The prevalence of parasitic infection among immunosuppressive patients in the present study was 16.7%. Entamoeba histolytica was the most commonly observed parasite. There was no significant association between prevalence of parasitic infections and socio-demographic data variables.

scholarly journals Uveitis in Patients with Ankylosing Spondylitis

2021 ◽  
Vol 19 (1) ◽  
pp. 97-100
Author(s):  
Anjal Bisht ◽  
Samrat Shrestha ◽  
Priya Bajgai ◽  
Milan Khadka ◽  
Parimal Koirala ◽  
...  
Keyword(s):  
Ankylosing Spondylitis ◽  
Tertiary Care ◽  
Close Correlation ◽  
Cross Sectional Study ◽  
Care Hospital ◽  
Cross Sectional ◽  
Prompt Treatment ◽  
Ocular Manifestations ◽  
Institutional Review ◽  
History Of

Background: There is a close correlation between ankylosing spondylitis and uveitis, other less common ocular manifestations being episcleritis and scleritis. Though the prognosis of uveitis is good, prompt treatment is required to prevent long-term complications. This study aimed to estimate the prevalence of uveitis in patients with ankylosing spondylitis who follow outpatient clinic of a tertiary care hospital.Methods: A descriptive cross-sectional study was done in medicine outpatient department of a tertiary care hospital for 6 months. Ethical clearance was obtained from the institutional review board of National Academy of Medical Sciences. Convenient sampling was done. The data collected were entered in Microsoft excel to tabulate the data and analyze the results.Results: Out of 81 participants, 26 patients had a history of uveitis (32%). Most of the patients in this study were of 18-30 years. Uveitis was most common in patients with (axial to be added) spondylarthritis and peripheral inflammatory arthritis (41%) compared to those with just the axial disease (32%). Uveitis was more common among males (32.2%) than females (31.5%).Conclusion: In patients with spondyloarthritis uveitis was present in 32% of the patient with more common in patient with both axial and peripheral arthritis. Timely diagnosis of uveitis in ankylosing spondylitis can prevent the sequelae with prompt treatment. Keywords: Ankylosing spondylitis; spondyloarthritis; uveitis

Frequency of Thrombocytopenia in Neonatal Sepsis

2021 ◽  
Vol 15 (10) ◽  
pp. 3381-3383
Author(s):  
Naheem Ahmed ◽  
Khawaja Tahir Aziz ◽  
Rashada Bibi ◽  
Munazza Nazir ◽  
Sadaf Nawaz ◽  
...  
Keyword(s):  
Neonatal Sepsis ◽  
Demographic Data ◽  
Tertiary Care ◽  
Cross Sectional Study ◽  
Care Hospital ◽  
Cross Sectional ◽  
Maternal Hypertension ◽  
Neonatal Thrombocytopenia ◽  
The Mean ◽  
And Gender

Objective: To determine the frequency of neonatal thrombocytopenia among patients presented with sepsis at tertiary care Hospital. Methodology: This cross-sectional study was conducted at the Department of pediatrics SKBZ/CMH Muzaffarabad, during six months from September 2018 to March 2019. All the diagnosed septic neonates, age < 28 days and either gender were included. Their basic demographic data like age and gender, along with their contact details were taken. The sample of blood was sent in blood culture bottles to hospital laboratory to confirm bacterial growth, that was diagnosed as sepsis. Blood sample was sent to the hospital also to diagnose thrombocytopenia. Reports were consulted by the pathologist. All the data were collected by a structured study proforma. All data were entered and analyzed with the help of SPSS version 22. Results: The mean age of patients was 8.92 ± 5.40 days with minimum and maximum age as 1 and 27 days. There were 117(47.56%) males and 129(52.44%) female cases. A total of 40(16.26%) cases had their maternal hypertension, 54(21.95%) neonates had gram + and 157(63.82%) neonates had Gram negative. A total of 63(25.61%) cases had thrombocytopenia while 183(74.39%) neonates were seen without thrombocytopenia. The frequency of thrombocytopenia was statistically insignificant according to gender and types of culture (p->0.05). Conclusion: It is concluded that frequency of thrombocytopenia in neonatal sepsis was found in a quarter of the cases. In neonatal sepsis, thrombocytopenia must be ruled out at patient’s presentation and must be treated as early as possible as thrombocytopenia is an independent risk factor for sepsis-associated mortality. Keywords: Incidence, thrombocytopenia, neonatal sepsis

scholarly journals A study of congenital anomalies in a tertiary care hospital in North East region, India

2018 ◽  
Vol 7 (7) ◽  
pp. 2899 ◽  
Author(s):  
Kangjam Radhesana Devi ◽  
R. K. Praneshwari Devi ◽  
Jyoti Priya ◽  
Ahanthembi Sanaton ◽  
Leimapokpam Roshan Singh ◽  
...  
Keyword(s):  
Congenital Anomalies ◽  
Congenital Malformations ◽  
Maternal Age ◽  
Cleft Lip ◽  
Tertiary Care ◽  
Cross Sectional Study ◽  
Care Hospital ◽  
Cross Sectional ◽  
North East ◽  
Still Births

Background: Congenital anomalies are important cause of morbidity and mortality in newborns and are defined as structural and functional abnormalities including metabolic disorders present at birth. These defects are of prenatal origin resulting from defective embryogenesis or intrinsic abnormalities in the process of development and are associated with various risk factors.Methods: Our study is a cross-sectional study done at Regional Institute of Medical Sciences, Imphal over period of one and half years from May 2016 to October 2017. Aim of study was to find out incidence of congenital anomalies and proportions of different types of congenital anomalies. Outcome was studied in relation to maternal age, religion, parity, gestational age, sex of baby, outcome and birth weight of baby.Results: Total numbers of congenital anomalies were 91 out of 13658 births. Incidence of congenital anomalies was 0.66%. Most common congenital anomaly was cleft lip (17.6%) followed by CTEV (13.2%) and was more common among male term babies. These were most common in 18-24 years of maternal age group (34.1%) followed by 30-34 years (26.4%) and among women of parity P0-P2.Conclusions: Congenital malformations are a major cause of still births and infant mortality. A level II targeted scan should be done at 18-20 weeks to find out anomalies and reduce the prevalence. There should be widespread education in the community regarding the common congenital malformations, their outcomes and possible available modes of treatment. 

scholarly journals IMPACT OF COVID-19 ON HEMATOLOGICAL PARAMETERS-A SINGLE CENTRE STUDY, INDIA.

2020 ◽  
pp. 4-6
Author(s):  
Reshma Anegundi ◽  
Talari Rajeswari ◽  
Arathi C A ◽  
Raghavendra M S
Keyword(s):  
Complete Blood Count ◽  
Hematological Parameters ◽  
Demographic Data ◽  
Tertiary Care ◽  
Systemic Infection ◽  
Cross Sectional Study ◽  
Care Hospital ◽  
Single Centre ◽  
Cross Sectional ◽  
Distribution Width

Aims and Objectives: To analyze various hematological parameters in Covid-19 infected patients. Patients/Materials and Methods: This is a retrospective, single centre cross sectional study conducted in a tertiary care hospital, located in a tri-state region. Data was collected from patients admitted in Covid-19 ward and ICU between 28 July to 7 September 2020, confirmed positive for Covid-19 infection. Basic demographic data was collected from Laboratory Information System(LIS) of our hospital . Whole blood EDTA sample sent from Covid-19 ward and ICU were processed in LH780/DXH 500(Beckman coulter) for complete blood counts. Further patients laboratory features were analyzed . Results: Findings of 338 patients, both from ward and ICU, showed varied hematological parameters. Demographic data revealed age range from 1day to 86 years. Males constituted 205(60.65%) and females 133(39.34%).Complete blood count showed Hemoglobin(Hb) concentration ranged from 5.8 -18.5gm/dL and median value 13.6gm/dL. Red cell distribution width(RDW) ranged from 11.4-39.9% with median value of 13.6%. Leucocytosis was observed in 13.9% of patients, high absolute neutrophil count in 15.6% ,high Neutrophil to Lymphocyte ratio(NLR) in 10.05% patients and eosinophil count ranged from 0-15.3%. Conclusion: Baseline alterations in CBC parameters of 10-15% of patients in the present study along with articles reviewed from various countries indicate Covid -19 infection causes systemic infection involving multiple organs and systems.

scholarly journals Pattern of Psychiatric Referral in a Tertiary Care Hospital in Bangladesh

2020 ◽  
Vol 31 (2) ◽  
pp. 76-80
Author(s):  
Sultana Algin ◽  
Sumaiya Nawsheen Ahmed ◽  
Redwana Hossain
Keyword(s):  
Demographic Data ◽  
Tertiary Care ◽  
Cross Sectional Study ◽  
Medical Illness ◽  
Care Hospital ◽  
Obsessive Compulsive ◽  
Liaison Psychiatry ◽  
Cross Sectional ◽  
Psychiatric Comorbidities ◽  
Compulsive Disorder

Introduction: Consultation-liaison Psychiatry (CLP) is the study, practice and teaching of the relationbetween medical and psychiatric disorders. Aim of the study: The aim of this study is to find out the referring department, reason for consultation,common psychiatric comorbidities and sociodemographic of the referred patients to psychiatrydepartment from the other departments of Bangabandhu Sheikh Mujib Medical University of Dhaka. Methodology: This cross-sectional study was carried out from May 2018 to February 2020. Patientsreferred from different inpatient departments every Thursday were taken as study population.Psychiatric diagnoses of the patients were assigned by the consultant psychiatrist as per DSM-5criteria. Semi structured questionnaire was used to collect socio-demographic data. Results: Among the referred patients (n= 89) 56% were female; 63% were aged between 19-59years; 65% were married; 58% were from urban background and 51% studied up to higher secondary.More than half of the patients were referred from different branches of Medicine (68%). Referral fromInternal Medicine was 14.6%, Rheumatology 13.5%, Neurology and Nephrology 10% respectively.The rest were from the branches of pediatrics, surgery and gynecology. Most common psychiatricdisorder was Major Depressive Disorder (37%) followed by Obsessive-Compulsive Disorder (17%)and Delirium (10.11%). 15% patient received no psychiatric diagnosis. Conclusion: Psychiatric comorbidities in general medical illness are very common. CLP provides anopportunity to improve health outcomes for inpatients and reduce burden on the healthcare system. Bangladesh J Medicine July 2020; 31(2) :76-80

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