scholarly journals IMPACT OF COVID-19 ON HEMATOLOGICAL PARAMETERS-A SINGLE CENTRE STUDY, INDIA.

2020 ◽  
pp. 4-6
Author(s):  
Reshma Anegundi ◽  
Talari Rajeswari ◽  
Arathi C A ◽  
Raghavendra M S
Keyword(s):  
Complete Blood Count ◽  
Hematological Parameters ◽  
Demographic Data ◽  
Tertiary Care ◽  
Systemic Infection ◽  
Cross Sectional Study ◽  
Care Hospital ◽  
Single Centre ◽  
Cross Sectional ◽  
Distribution Width

Aims and Objectives: To analyze various hematological parameters in Covid-19 infected patients. Patients/Materials and Methods: This is a retrospective, single centre cross sectional study conducted in a tertiary care hospital, located in a tri-state region. Data was collected from patients admitted in Covid-19 ward and ICU between 28 July to 7 September 2020, confirmed positive for Covid-19 infection. Basic demographic data was collected from Laboratory Information System(LIS) of our hospital . Whole blood EDTA sample sent from Covid-19 ward and ICU were processed in LH780/DXH 500(Beckman coulter) for complete blood counts. Further patients laboratory features were analyzed . Results: Findings of 338 patients, both from ward and ICU, showed varied hematological parameters. Demographic data revealed age range from 1day to 86 years. Males constituted 205(60.65%) and females 133(39.34%).Complete blood count showed Hemoglobin(Hb) concentration ranged from 5.8 -18.5gm/dL and median value 13.6gm/dL. Red cell distribution width(RDW) ranged from 11.4-39.9% with median value of 13.6%. Leucocytosis was observed in 13.9% of patients, high absolute neutrophil count in 15.6% ,high Neutrophil to Lymphocyte ratio(NLR) in 10.05% patients and eosinophil count ranged from 0-15.3%. Conclusion: Baseline alterations in CBC parameters of 10-15% of patients in the present study along with articles reviewed from various countries indicate Covid -19 infection causes systemic infection involving multiple organs and systems.

scholarly journals A study of serum electrolytes level in viral hepatitis E patients in a tertiary care hospital of south Gujarat

2021 ◽  
Vol 8 (11) ◽  
pp. 1710
Author(s):  
Ravi Shah ◽  
Parshv Shah ◽  
Hemant Shah ◽  
Nilesh Doctor
Keyword(s):  
Viral Hepatitis ◽  
Hepatitis E Virus ◽  
Total Bilirubin ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Hepatitis E ◽  
Cross Sectional Study ◽  
Care Hospital ◽  
Single Centre ◽  
Cross Sectional

Background: the aim of the study was to find and understand the relation between electrolytes and viral hepatitis E. To study electrolyte abnormality in patients with hepatitis E virus (HEV).Methods: This study is a single centre cross sectional study on the patients with HEV infection. Consecutive cases affected with HEV-at department of medicine, SMIMER (Surat Municipal institute of medical education and research) hospital, Surat during the period of 1 year (July-2019 to June-2020) are taken up for the study.Results: Abnormal electrolytes are associated with higher mortality in patients infected with HEV.Conclusions: A higher mean serum creatinine, total bilirubin, SGOT, SGPT; lower total protein, albumin, and abnormal electrolytes in body fluid (Na+, K+, Cl-, Ca++) values are associated with higher mortality in patients infected with HEV.

scholarly journals Anti-microbial sensitivity and resistance of organisms in blood-culture samples from prolonged fever cases: evidence from a tertiary care hospital in West Bengal, India

2018 ◽  
Vol 7 (11) ◽  
pp. 2173
Author(s):  
Somanjana Ghosh ◽  
Arista Lahiri ◽  
Siddhartha Bera ◽  
Soumyajyoti Bandyopadhyay
Keyword(s):  
Blood Culture ◽  
Tertiary Care ◽  
Systemic Infection ◽  
Cross Sectional Study ◽  
Background Information ◽  
Resistance Pattern ◽  
Coagulase Negative Staphylococcus ◽  
Care Hospital ◽  
Cross Sectional ◽  
High Level

Background: Currently there is a rise in resistance to anti-microbials which is a matter of concern in treatment of systemic infections. Blood culture is considered “gold standard” in diagnosis of suspected systemic infection. The susceptibility to antibiotics thereafter determine the future course of treatment. The current study aims to find out the sensitivity and resistance pattern of the blood culture isolates.Methods: A cross-sectional study was performed on the blood culture samples sent within 24hours of admission of the adult patients reporting fever for 7 days or more with no history of consumption of any antibiotics within last month. Total 134 blood samples were analysed. The proportion of sensitivity and resistance to anti-bacterial agents was calculated among those samples which showed growth in the culture. Background information of the patients in terms of age, sex and religion were also noted.Results: Mean age of the patients was 39.33 (±12.19) years. Overall 47.76% were female patients and remaining were male. Among the Hindu patients majority were male while among Muslims majority were female. Of the total number of blood cultures examined 46.27% showed growth of bacteria. Staphylococcus aureus was the most frequently found bacteria isolated in cultures, followed by coagulase negative Staphylococcus and Pseudomonas. Of the frequently used antibiotics, higher sensitivity was seen with vancomycin, amikacin, netilmycin, imipenem, gentamicin. High resistance was observed in use of antibiotics like cefixime, amoxicillin-clavulanic acid and azithromycin.Conclusions: High level of resistance to several commonly used advanced antibiotics warrant judicial and evidence-based use of these drugs. 

scholarly journals Histopathological Study of Post-Surgical Gallbladder to Establish True Histopathology Proven Chronic Inflammation

2021 ◽  
Vol 8 (3) ◽  
pp. 15-19
Author(s):  
Tania Khattak ◽  
Almas Khattak ◽  
Susan Kakakhel ◽  
Anwar Ul Haque
Keyword(s):  
Chronic Inflammation ◽  
Demographic Data ◽  
Descriptive Analysis ◽  
Tertiary Care ◽  
Cross Sectional Study ◽  
Chronic Cholecystitis ◽  
Histopathological Study ◽  
Care Hospital ◽  
Histopathological Changes ◽  
Cross Sectional

OBJECTIVES: The aim of this study was to establish true histopathology proven diagnosis of chronic cholecystitis. METHODOLOGY: A cross-sectional study was conducted on 51 post-surgical gallbladders was done to assess their histopathological patterns in a single centered tertiary care hospital. The specimens were studied for chronic cholecystitis, fibrosis, hypertrophy and presence of Rokitansky-Aschoff sinuses. Descriptive analysis was done and associations of the histopathological changes with demographic data of patients were analyzed through Chi-squared test. RESULTS: Fifty-one post cholecystectomy samples of gallbladder were analyzed for histopathological changes with 82.4% showing chronic cholecystitis, 84.3% fibrosis, 64.7% congestion, and more than 60% mild or moderate hypertrophy. Moreover, 49% of the specimens showed Rokitansky-Aschoff sinuses. All these changes suggest chronic inflammation. CONCLUSION: Chronic cholecystitis, fibrosis, and Rokitansky-Aschoff sinuses are the most common histopathological findings in specimens of patients undergone cholecystectomy for cholelithiasis.  

scholarly journals Prevalence of Dental Anomalies in the Patient with Cleft Lip and Palate Visiting a Tertiary Care Hospital

2020 ◽  
Vol 58 (228) ◽  
Author(s):  
Leeza Pradhan ◽  
Pramila Shakya ◽  
Swosti Thapa ◽  
Kiran Kishor Nakarmi ◽  
Anjana Maharjan ◽  
...  
Keyword(s):  
Cleft Lip ◽  
Cleft Lip And Palate ◽  
Demographic Data ◽  
Tertiary Care ◽  
Cross Sectional Study ◽  
Lateral Incisor ◽  
Care Hospital ◽  
Dental Anomalies ◽  
Cross Sectional ◽  
Institutional Review

Introduction: Dental anomaly is one of the major problems in a child born with cleft lip and palate. These anomalies have deleterious effects on the dentition leading to aesthetic problems, impairment of mastication andimproper phonation. The aim of our study was to find out the prevalence of dental anomalies in patient with cleft lip and/or palate radiographically. Methods: A descriptive cross-sectional study was conducted from the 208 radiographs, collected by the convenience samplingtechnique with cleft lip and/or palate in Department of Burns, Plastic and Reconstructive Surgery, Nepal Cleft and Burn Centre, Kirtipur Hospital from January 2017 to July 2019.Ethical clearance for the study was obtained from Institutional Review Committee. Demographic data were collected and radiographs were evaluated for possible dental anomalies. Data obtained were entered and analysed in Statistical Package for Social Sciences version 23. Results: Dental anomalies were highly prevalent among cleft lip and palate patients with at least one anomaly present in 188 (90.4%) of patients with male 120 (57.4%) presenting more anomalies than female 88 (42.6%) population. The most common anomaly was dental agenesis 161 (77.9%). The prevalence of positional anomaly, morphological anomaly and supernumerary teeth were found to be 54 (26%), 33 (15.9%) and 20 (10%) respectively. Lateral incisor showed the highest incidence of agenesis among all other missing teeth 223 (65.2%). Conclusions: The prevalence of dental anomalies among patients with cleft lip and/or palate was found to be high. Tooth agenesis was the most common anomaly observed in the study with lateral incisor having the highest incidence of agenesis.

scholarly journals Study of Parasitic Infection in Immunosuppressive Patients and its Association with the Socio-demographic Status

2021 ◽  
Author(s):  
J Lakhani Sucheta ◽  
Dhruba Hari Chandi ◽  
J Lakhani Som
Keyword(s):  
Entamoeba Histolytica ◽  
Close Contact ◽  
Demographic Data ◽  
Tertiary Care ◽  
Parasitic Infection ◽  
Cross Sectional Study ◽  
Parasitic Infections ◽  
P Value ◽  
Care Hospital ◽  
Cross Sectional

Introduction: In developing countries, immunosuppressive patients are at greater risk of parasitic infection which may cause morbidity and mortality. Socio-economic and environmental factors including lack of health hygiene in close contact with infected reservoir animal which plays an important role. Aim: To determine the prevalence of parasitic infections and their association with socio-demographic status. Materials and Methods: This was a cross-sectional study which was carried out at tertiary care hospital located in Central East India. Total 120 stool samples were collected from the immunosuppressive patients and were processed using direct wet mount preparation with saline and Lugol, formalin-ether concentration and Modified Ziehl-Neelsen stain. Different socio-demographic parameters were recorded. Statistical analysis was done using Graph Pad Prism version 8 Chi-square test. The p-value ≤0.05 was considered as statistically significant Results: Out of total 120 patients, 20 (16.7%) were found to be infected. Majority of the population were males (66.7%). Among the total positive samples, 75% (15) showed the presence of Protozoa in which 10 samples had Entamoeba histolytica. The presence of Helminths was found in 25% (5), in which three samples showed Ascaris lumbricoides and two had Taenia species (10%). Conclusion: The prevalence of parasitic infection among immunosuppressive patients in the present study was 16.7%. Entamoeba histolytica was the most commonly observed parasite. There was no significant association between prevalence of parasitic infections and socio-demographic data variables.

Frequency of Thrombocytopenia in Neonatal Sepsis

2021 ◽  
Vol 15 (10) ◽  
pp. 3381-3383
Author(s):  
Naheem Ahmed ◽  
Khawaja Tahir Aziz ◽  
Rashada Bibi ◽  
Munazza Nazir ◽  
Sadaf Nawaz ◽  
...  
Keyword(s):  
Neonatal Sepsis ◽  
Demographic Data ◽  
Tertiary Care ◽  
Cross Sectional Study ◽  
Care Hospital ◽  
Cross Sectional ◽  
Maternal Hypertension ◽  
Neonatal Thrombocytopenia ◽  
The Mean ◽  
And Gender

Objective: To determine the frequency of neonatal thrombocytopenia among patients presented with sepsis at tertiary care Hospital. Methodology: This cross-sectional study was conducted at the Department of pediatrics SKBZ/CMH Muzaffarabad, during six months from September 2018 to March 2019. All the diagnosed septic neonates, age < 28 days and either gender were included. Their basic demographic data like age and gender, along with their contact details were taken. The sample of blood was sent in blood culture bottles to hospital laboratory to confirm bacterial growth, that was diagnosed as sepsis. Blood sample was sent to the hospital also to diagnose thrombocytopenia. Reports were consulted by the pathologist. All the data were collected by a structured study proforma. All data were entered and analyzed with the help of SPSS version 22. Results: The mean age of patients was 8.92 ± 5.40 days with minimum and maximum age as 1 and 27 days. There were 117(47.56%) males and 129(52.44%) female cases. A total of 40(16.26%) cases had their maternal hypertension, 54(21.95%) neonates had gram + and 157(63.82%) neonates had Gram negative. A total of 63(25.61%) cases had thrombocytopenia while 183(74.39%) neonates were seen without thrombocytopenia. The frequency of thrombocytopenia was statistically insignificant according to gender and types of culture (p->0.05). Conclusion: It is concluded that frequency of thrombocytopenia in neonatal sepsis was found in a quarter of the cases. In neonatal sepsis, thrombocytopenia must be ruled out at patient’s presentation and must be treated as early as possible as thrombocytopenia is an independent risk factor for sepsis-associated mortality. Keywords: Incidence, thrombocytopenia, neonatal sepsis

scholarly journals Pattern of Psychiatric Referral in a Tertiary Care Hospital in Bangladesh

2020 ◽  
Vol 31 (2) ◽  
pp. 76-80
Author(s):  
Sultana Algin ◽  
Sumaiya Nawsheen Ahmed ◽  
Redwana Hossain
Keyword(s):  
Demographic Data ◽  
Tertiary Care ◽  
Cross Sectional Study ◽  
Medical Illness ◽  
Care Hospital ◽  
Obsessive Compulsive ◽  
Liaison Psychiatry ◽  
Cross Sectional ◽  
Psychiatric Comorbidities ◽  
Compulsive Disorder

Introduction: Consultation-liaison Psychiatry (CLP) is the study, practice and teaching of the relationbetween medical and psychiatric disorders. Aim of the study: The aim of this study is to find out the referring department, reason for consultation,common psychiatric comorbidities and sociodemographic of the referred patients to psychiatrydepartment from the other departments of Bangabandhu Sheikh Mujib Medical University of Dhaka. Methodology: This cross-sectional study was carried out from May 2018 to February 2020. Patientsreferred from different inpatient departments every Thursday were taken as study population.Psychiatric diagnoses of the patients were assigned by the consultant psychiatrist as per DSM-5criteria. Semi structured questionnaire was used to collect socio-demographic data. Results: Among the referred patients (n= 89) 56% were female; 63% were aged between 19-59years; 65% were married; 58% were from urban background and 51% studied up to higher secondary.More than half of the patients were referred from different branches of Medicine (68%). Referral fromInternal Medicine was 14.6%, Rheumatology 13.5%, Neurology and Nephrology 10% respectively.The rest were from the branches of pediatrics, surgery and gynecology. Most common psychiatricdisorder was Major Depressive Disorder (37%) followed by Obsessive-Compulsive Disorder (17%)and Delirium (10.11%). 15% patient received no psychiatric diagnosis. Conclusion: Psychiatric comorbidities in general medical illness are very common. CLP provides anopportunity to improve health outcomes for inpatients and reduce burden on the healthcare system. Bangladesh J Medicine July 2020; 31(2) :76-80

scholarly journals Stroke patients presenting to the emergency department of a tertiary care hospital

2021 ◽  
Vol 8 (2) ◽  
pp. 85-90
Author(s):  
Suraj Rijal ◽  
Sunil Adhikari ◽  
Darlene Rose House
Keyword(s):  
Emergency Department ◽  
Demographic Data ◽  
Tertiary Care ◽  
Cross Sectional Study ◽  
Common Disease ◽  
Care Hospital ◽  
Stroke Patients ◽  
Cross Sectional ◽  
Presenting Symptoms ◽  
Ethical Approval

Introduction: Stroke is one of the most common causes of morbidity and mortality in Nepal. It is the 3rd most common cause of death worldwide. In Nepal Non-communicable diseases in Nepal(NCDs) states that stroke accounts for 42% of all deaths and is estimated to reach about 66.3% of all deaths by 2030. Method: A retrospective cross-sectional study of all stroke patients seen in Patan Hospital Emergency Department for a period of 1 y. Demographic data, presenting complaint, time of onset of symptoms, time presenting to the Emergency, patient’s risk factors for stroke, head CT findings (hemorrhagic or ischemic stroke) were analyzed descriptively. Ethical approval was taken. Result: Total 170 patients (96 males i.e.56.5% and 74 females i.e. 43.5%) were analyzed. 130(76.5%) were ischemic CVA and 40 (23.5%) were hemorrhagic CVA. The most common presenting symptoms was hemiparesis and speech changes. Conclusion: Stroke is a common disease seen in Nepal, with higher percentages of hemorrhagic stroke.

scholarly journals Role of platelet parameters and hematological profile in dengue positive cases

2021 ◽  
Vol 8 (1) ◽  
pp. 23
Author(s):  
Rashim Passi ◽  
B. P. Baviskar ◽  
R. R. Karle
Keyword(s):  
Platelet Count ◽  
Hematological Parameters ◽  
Dengue Infection ◽  
Tertiary Care ◽  
Care Hospital ◽  
Cross Sectional ◽  
Distribution Width ◽  
Platelet Indices ◽  
Ns1 Antigen

<p class="abstract"><strong>Background:</strong> Dengue is an endemic in tropical and sub-tropical regions of the world and also in various parts of India. Recent evidence indicates that platelet indices can be used to assess the severity and prognosis of dengue. This study aimed to assess the role of the platelet indices-mean platelet volume (MPV), platelet distribution width (PDW), platelet to large cell ratio (P-LCR), plateletcrit (Pct) and hematological parameters like hemoglobin (Hb), hematocrit (Hct) with the platelet count in dengue NS1 antigen positive cases.</p><p class="abstract"><strong>Methods:</strong> An observational cross-sectional study conducted on cases of dengue over a period of 3 months admitted with serological positivity (NS1 antigen) in a tertiary care hospital, Loni. The platelet indices like MPV, PDW, Pct, P-LCR and hematological parameters like Hb, Hct were noted using Sysmex XN-3100 Automated hematology analyzer and compared with platelet count.</p><p class="abstract"><strong>Results:</strong> Relationship between various platelet indices like MPV, PDW, P-LCR and PCT and hematological parameters like Hb, TLC and Hct were related with platelet count. Dengue positive cases were inversely related to MPV, PDW, P-LCR, Hb and Hct and directly related to Pct. In the present study Pct, P-LCR, Hb and Hct were statistically significant in correlation with platelet count.</p><p class="abstract"><strong>Conclusions:</strong> Pct, P-LCR, Hb and Hct along with platelet count can be used to assess the predictive outcomes in case of dengue infection.</p><p>.</p>

scholarly journals Acute Urticaria in Children in a Tertiary Care Hospital: A Cross-sectional Study

2021 ◽  
Author(s):  
Kannu Priya ◽  
Anupama Vinayak Mauskar
Keyword(s):  
Complete Blood Count ◽  
Tertiary Care ◽  
Cross Sectional Study ◽  
Care Hospital ◽  
Age Group ◽  
Cross Sectional ◽  
Prick Test ◽  
Acute Urticaria ◽  
Excessive Heat ◽  
History Of

Introduction: Urticaria is a highly prevalent condition resulting in a large number of medical consultancies worldwide. Urticaria is derived from the Latin word “urere” meaning “to burn”. Urticaria usually manifests as a transient, itchy, polymorphic skin eruption. It can occur in any age group. Aim: To study the prevalence and possible triggers of acute urticaria in children. Materials and Methods: All children of age group six months to 12 years visiting the Institute from June 2018 to April 2019, with the complaint of acute urticaria with or without angioedema were included in the study while those with chronic urticaria and only angioedema were excluded. Sixty five children presented with acute urticaria with or without angioedema. Patients were diagnosed based on history and clinical examination. All patients were subjected to a detailed history, general physical examination and, necessary investigations like Complete Blood Count (CBC), absolute eosinophil count, Erythrocyte Sedimentation Rate (ESR), C-reactive Protein (CRP), Skin Prick test as indicated. They received appropriate treatment and their clinical outcome was studied. Results: Prevalence of acute urticaria was found to be 0.23. It was more commonly seen in males (63.08%) and more in the age group of 1 to 5 years (56.92%). The focus of infection was found in 44.6% of children, while 21% of children had a history of consumption of some form of medications leading to urticaria. Conclusion: Urticaria can be prevented in children by preventing them from infection and avoiding the use of amoxicillin-clavulanic acid unless very necessary. Those children with a family history of acute urticaria should be prevented from exposure to excessive heat, cold, pressure, vibration, etc. Investigations are also recommended as an important diagnostic tool to find out the aetiology of acute urticaria.

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