Frequency of Thrombocytopenia in Neonatal Sepsis

2021 ◽  
Vol 15 (10) ◽  
pp. 3381-3383
Author(s):  
Naheem Ahmed ◽  
Khawaja Tahir Aziz ◽  
Rashada Bibi ◽  
Munazza Nazir ◽  
Sadaf Nawaz ◽  
...  
Keyword(s):  
Neonatal Sepsis ◽  
Demographic Data ◽  
Tertiary Care ◽  
Cross Sectional Study ◽  
Care Hospital ◽  
Cross Sectional ◽  
Maternal Hypertension ◽  
Neonatal Thrombocytopenia ◽  
The Mean ◽  
And Gender

Objective: To determine the frequency of neonatal thrombocytopenia among patients presented with sepsis at tertiary care Hospital. Methodology: This cross-sectional study was conducted at the Department of pediatrics SKBZ/CMH Muzaffarabad, during six months from September 2018 to March 2019. All the diagnosed septic neonates, age < 28 days and either gender were included. Their basic demographic data like age and gender, along with their contact details were taken. The sample of blood was sent in blood culture bottles to hospital laboratory to confirm bacterial growth, that was diagnosed as sepsis. Blood sample was sent to the hospital also to diagnose thrombocytopenia. Reports were consulted by the pathologist. All the data were collected by a structured study proforma. All data were entered and analyzed with the help of SPSS version 22. Results: The mean age of patients was 8.92 ± 5.40 days with minimum and maximum age as 1 and 27 days. There were 117(47.56%) males and 129(52.44%) female cases. A total of 40(16.26%) cases had their maternal hypertension, 54(21.95%) neonates had gram + and 157(63.82%) neonates had Gram negative. A total of 63(25.61%) cases had thrombocytopenia while 183(74.39%) neonates were seen without thrombocytopenia. The frequency of thrombocytopenia was statistically insignificant according to gender and types of culture (p->0.05). Conclusion: It is concluded that frequency of thrombocytopenia in neonatal sepsis was found in a quarter of the cases. In neonatal sepsis, thrombocytopenia must be ruled out at patient’s presentation and must be treated as early as possible as thrombocytopenia is an independent risk factor for sepsis-associated mortality. Keywords: Incidence, thrombocytopenia, neonatal sepsis

scholarly journals PREVALENCE OF COMORBIDITIES AND THEIR IMPACT ON MORTALITY IN COVID-19 PATIENTS - A CROSS SECTIONAL STUDY IN A TERTIARY CARE COVID HOSPITAL.

2020 ◽  
pp. 12-14
Author(s):  
S. Durga Prasad ◽  
K. V. Seshaiah ◽  
P. Praveen Kumar ◽  
A. Sita Kanthima ◽  
K.S.S. Harshitha ◽  
...  
Keyword(s):  
Medical Records ◽  
Severe Disease ◽  
Tertiary Care ◽  
Cross Sectional Study ◽  
Rapid Progression ◽  
Care Hospital ◽  
Sectional Study ◽  
Cross Sectional ◽  
And Gender ◽  
Short Time

Background: Since the origin of novel corona virus (COVID-19) in December 2019, it engulfed more than 200 countries worldwide within short time and was declared as pandemic by WHO. Even though the overall fatality rate is low in COVID-19, presence of certain risk factors and comorbidities more likely result in severe disease and subsequent mortality. Methodology: Retrospectively we evaluated the details of total 200 COVID-19 patients from the medical records. These 200 patients include two groups. Each group consisted of 100 patients. One group consisted 100 patients who were discharged successfully after recovery from COVID-19. Second group consisted 100 patients who demised during hospital stay with COVID-19. We have studied prevalence of comorbidities and their impact on mortality in these two groups in relation to gender, severity. This was a cross sectional study of COVID-19 patients admitted from 01-04-2020 to 31-05-2020 (period of two months) in our state COVID tertiary care hospital, Vijayawada, Andhra Pradesh. Results: There was no statistically significant association between presence of comorbidities and gender in relation to mortality. There was statistically significant association between presence of comorbidities and severity of disease. The association of comorbidities and mortality was statistically significant. Conclusion: Patients with COVID-19 who have comorbidities are more likely to have severe disease course, rapid progression, increased need for admission in ICU and mortality.

scholarly journals Histopathological Study of Post-Surgical Gallbladder to Establish True Histopathology Proven Chronic Inflammation

2021 ◽  
Vol 8 (3) ◽  
pp. 15-19
Author(s):  
Tania Khattak ◽  
Almas Khattak ◽  
Susan Kakakhel ◽  
Anwar Ul Haque
Keyword(s):  
Chronic Inflammation ◽  
Demographic Data ◽  
Descriptive Analysis ◽  
Tertiary Care ◽  
Cross Sectional Study ◽  
Chronic Cholecystitis ◽  
Histopathological Study ◽  
Care Hospital ◽  
Histopathological Changes ◽  
Cross Sectional

OBJECTIVES: The aim of this study was to establish true histopathology proven diagnosis of chronic cholecystitis. METHODOLOGY: A cross-sectional study was conducted on 51 post-surgical gallbladders was done to assess their histopathological patterns in a single centered tertiary care hospital. The specimens were studied for chronic cholecystitis, fibrosis, hypertrophy and presence of Rokitansky-Aschoff sinuses. Descriptive analysis was done and associations of the histopathological changes with demographic data of patients were analyzed through Chi-squared test. RESULTS: Fifty-one post cholecystectomy samples of gallbladder were analyzed for histopathological changes with 82.4% showing chronic cholecystitis, 84.3% fibrosis, 64.7% congestion, and more than 60% mild or moderate hypertrophy. Moreover, 49% of the specimens showed Rokitansky-Aschoff sinuses. All these changes suggest chronic inflammation. CONCLUSION: Chronic cholecystitis, fibrosis, and Rokitansky-Aschoff sinuses are the most common histopathological findings in specimens of patients undergone cholecystectomy for cholelithiasis.  

scholarly journals Prevalence of Dental Anomalies in the Patient with Cleft Lip and Palate Visiting a Tertiary Care Hospital

2020 ◽  
Vol 58 (228) ◽  
Author(s):  
Leeza Pradhan ◽  
Pramila Shakya ◽  
Swosti Thapa ◽  
Kiran Kishor Nakarmi ◽  
Anjana Maharjan ◽  
...  
Keyword(s):  
Cleft Lip ◽  
Cleft Lip And Palate ◽  
Demographic Data ◽  
Tertiary Care ◽  
Cross Sectional Study ◽  
Lateral Incisor ◽  
Care Hospital ◽  
Dental Anomalies ◽  
Cross Sectional ◽  
Institutional Review

Introduction: Dental anomaly is one of the major problems in a child born with cleft lip and palate. These anomalies have deleterious effects on the dentition leading to aesthetic problems, impairment of mastication andimproper phonation. The aim of our study was to find out the prevalence of dental anomalies in patient with cleft lip and/or palate radiographically. Methods: A descriptive cross-sectional study was conducted from the 208 radiographs, collected by the convenience samplingtechnique with cleft lip and/or palate in Department of Burns, Plastic and Reconstructive Surgery, Nepal Cleft and Burn Centre, Kirtipur Hospital from January 2017 to July 2019.Ethical clearance for the study was obtained from Institutional Review Committee. Demographic data were collected and radiographs were evaluated for possible dental anomalies. Data obtained were entered and analysed in Statistical Package for Social Sciences version 23. Results: Dental anomalies were highly prevalent among cleft lip and palate patients with at least one anomaly present in 188 (90.4%) of patients with male 120 (57.4%) presenting more anomalies than female 88 (42.6%) population. The most common anomaly was dental agenesis 161 (77.9%). The prevalence of positional anomaly, morphological anomaly and supernumerary teeth were found to be 54 (26%), 33 (15.9%) and 20 (10%) respectively. Lateral incisor showed the highest incidence of agenesis among all other missing teeth 223 (65.2%). Conclusions: The prevalence of dental anomalies among patients with cleft lip and/or palate was found to be high. Tooth agenesis was the most common anomaly observed in the study with lateral incisor having the highest incidence of agenesis.

scholarly journals Mortality among organophosphate poisoning patients presenting with low Glasgow coma scale score at A Tertiary Care Hospital.

2020 ◽  
Vol 27 (10) ◽  
pp. 2187-2192
Author(s):  
Muhammad Ali ◽  
Vinod Kumar ◽  
Shafique Ahmed ◽  
Hina Iram ◽  
Sagheer Ahmed ◽  
...  
Keyword(s):  
Medical Center ◽  
Tertiary Care ◽  
Cross Sectional Study ◽  
Organophosphate Poisoning ◽  
Care Hospital ◽  
Cross Sectional ◽  
Practical Tool ◽  
The Subject ◽  
The Mean ◽  
Study Setting

This study is designed to assess the mortality in OPP patients with low GCS scores. Study Design: Cross Sectional study. Setting: Jinnah Postgraduate Medical Center. Period: From 1st February 2018 to 31st August 2018. Material & Methods: Included patients with low GCS, both genders and age of 18-60 years diagnosed with OPP. Their GCS was calculated and the outcome was determined in terms of mortality. Results: Out of 70 patients, the mean age was 35.2+16.5 years with the majority (62.9%) <30 years. 62.9% of these were males. Most (57.1%) of them presented after ingestion of <15mL of OP, 60% had the poisoning for >60 minutes, and the majority (74.3%) had taken it orally. When the GCS was computed, 81.40% had that of >5, while the mean came out to be 6.64 ±1.43. The mortality rate here was 17.10%. Conclusion: GCS toll can be a helpful and practical tool in assessing the mortality among the patients of OPP. However, because of the limited literature on the subject further studies are recommended to improve its validity.

scholarly journals Emergency Stay Duration of Patients in Emergency Department of A Tertiary Care Hospital in Nepal: A Descriptive Cross-sectional Study

2020 ◽  
Vol 58 (222) ◽  
Author(s):  
Prashant Simkhada ◽  
Shradha Acharya ◽  
Roshan Lama ◽  
Sujata Dahal ◽  
Nita Lohola ◽  
...  
Keyword(s):  
Emergency Department ◽  
Length Of Stay ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Cross Sectional Study ◽  
Care Hospital ◽  
Sectional Study ◽  
Cross Sectional ◽  
Duration Of Stay ◽  
The Mean

Introduction: Emergency department of a hospital is responsible for providing medical and surgical care to patients arriving at the hospital in need of immediate care. Emergency department is not staffed or equipped to provide prolonged care. Duration of stay in the Emergency department directly affects the quality of patient care. Longer length of stay is associated with Emergency department overcrowding, decline in patient care, increased mortality and decreased patients satisfaction. The main aim of this study is to find the mean stay duration of patients in the emergency department of a tertiary care hospital in Nepal.Methods: This is a descriptive cross-sectional study which was conducted in a tertiary care teaching hospital from Jan 15,2019 to Jan 30, 2019. Ethical clearance was obtained from Kathmandu Medical College- Instutional Review Committee. The calculated sample size was 587. Consecutive sampling technique was used. The data thus obtained was entered in SPSS version 20 and necessary calculations were done. Results: The mean emergency stay duration was obtained to be 3.18 hours at 95% confidence interval (C.I  and standard deviation was 2.51 hours. Female had longer mean duration of stay (3.25 hours) compared to male (3.11 hours). The maximum length of stay was 15.3 hours. Most of the patients attending the emergency department were discharged right through the emergency department 398 ( 67.8%). Mean duration of stay was longest (5.06 hours) for the referral group. Conclusions: The mean stay duration in Emergency Department of tertiary care hospital in Nepal is getting shorter compared to similar study done previously.

scholarly journals To explore the impact of following the pre-operative fasting guidelines by ASA (American society of anesthesiologists), in improving patient outcome.

2021 ◽  
Vol 28 (7) ◽  
pp. 1018-1021
Author(s):  
Maqsood Ahmed Siddiqui ◽  
◽  
Ashok Perchani ◽  
Hamid Raza ◽  
Ahmeduddin Soomro ◽  
...  
Keyword(s):  
Tertiary Care ◽  
Cross Sectional Study ◽  
Care Hospital ◽  
Start Time ◽  
Time Duration ◽  
Cross Sectional ◽  
Emergency Procedures ◽  
The Mean ◽  
The Impact ◽  
Mean Time

Objective: To analyze the occurrence and consequences of a prolonged preoperative-fasting. Study Design: Cross-sectional study. Setting: Large tertiary care hospital in Pakistan. Period: October 2018 to October 2019. Material & Methods: We collected data for all the procedures that occurred during the study period and divided the cases into emergency procedures, add-on procedures and elective cases. We excluded the first cases of the day and excluded the emergency and add-on cases. We studied the patients NPO duration and their scheduled start time of the procedure and compared with their actual start time of the procedure. Results: The study population was n= 434 cases. Of these 434 cases n= 164 cases were performed on time and n= 270 cases were delayed by 60 minutes or more from their scheduled time. The most frequent reason was a previous cases running longer than expected in 59.25% of the cases, the second most common reason was a change in sequence and order of the procedures which was the case for delay in 14.44% of the cases. The overall mean time of NPO for the patients was found to be 770.1 +/- 130.6 minutes, for the delayed cases the mean time duration of NPO was 812.3 +/- 105.3 minutes. The mean time of case delay was 155.2 +/- 102.7 minutes for overall cases and for the significantly delayed case the mean time period of delay was 190.2 +/- 92.1 cases. Conclusion: Our results showed that 60% of the cases have a prolonged NPO status due to delays in start of their surgical procedure as compared to the scheduled times.

scholarly journals Study of Parasitic Infection in Immunosuppressive Patients and its Association with the Socio-demographic Status

2021 ◽  
Author(s):  
J Lakhani Sucheta ◽  
Dhruba Hari Chandi ◽  
J Lakhani Som
Keyword(s):  
Entamoeba Histolytica ◽  
Close Contact ◽  
Demographic Data ◽  
Tertiary Care ◽  
Parasitic Infection ◽  
Cross Sectional Study ◽  
Parasitic Infections ◽  
P Value ◽  
Care Hospital ◽  
Cross Sectional

Introduction: In developing countries, immunosuppressive patients are at greater risk of parasitic infection which may cause morbidity and mortality. Socio-economic and environmental factors including lack of health hygiene in close contact with infected reservoir animal which plays an important role. Aim: To determine the prevalence of parasitic infections and their association with socio-demographic status. Materials and Methods: This was a cross-sectional study which was carried out at tertiary care hospital located in Central East India. Total 120 stool samples were collected from the immunosuppressive patients and were processed using direct wet mount preparation with saline and Lugol, formalin-ether concentration and Modified Ziehl-Neelsen stain. Different socio-demographic parameters were recorded. Statistical analysis was done using Graph Pad Prism version 8 Chi-square test. The p-value ≤0.05 was considered as statistically significant Results: Out of total 120 patients, 20 (16.7%) were found to be infected. Majority of the population were males (66.7%). Among the total positive samples, 75% (15) showed the presence of Protozoa in which 10 samples had Entamoeba histolytica. The presence of Helminths was found in 25% (5), in which three samples showed Ascaris lumbricoides and two had Taenia species (10%). Conclusion: The prevalence of parasitic infection among immunosuppressive patients in the present study was 16.7%. Entamoeba histolytica was the most commonly observed parasite. There was no significant association between prevalence of parasitic infections and socio-demographic data variables.

scholarly journals An epidemiological study of utilization of Rajiv Gandhi Jeevandayee Arogya Yojana in a municipal tertiary care hospital located in a metro city

2017 ◽  
Vol 4 (7) ◽  
pp. 2515
Author(s):  
Radhakrishnan A. ◽  
Seema S. Bansode-Gokhe
Keyword(s):  
Conservative Management ◽  
Medical Management ◽  
Tertiary Care ◽  
Cross Sectional Study ◽  
Care Hospital ◽  
Age Group ◽  
Cross Sectional ◽  
Purposeful Sampling ◽  
The Mean ◽  
Epidemiological Profile

Background: Objective of the study was to study the epidemiological profile of study subjects benefited by Rajiv Gandhi Jeevandayee Arogya Yojana (RGJAY) and study the spectrum of surgical procedures/therapies/consultations. Methods: It was a hospital record –based retrospective cross sectional study. Approximately 7200 beneficiaries were enrolled in a year. This study was analyzed with 10% beneficiaries (730) data by the convenient purposeful sampling method. Data was analyzed by using SPSS 17 software. Results: The majority of the study subjects (34.7%) belonged to the age group of 40-59 years. The mean age was 38.6.More study subjects were males (55.1%). 99.9% of study subjects had come directly without any referral. 95.2% study subjects were orange ration card holders, 4.1% were yellow ration card holders.78.8% of study subjects got approval from RGJAY society, whereas pre authorization status was cancelled in13.6%.In total surgeries majority of the study subjects utilized orthopaedics surgery (16.3%).In total therapies majority utilized paediatric medical management (18.5%). In conservative management majority utilized cardiology (94.7%) and burns (5.2%). Conclusions: The majority of the study subjects belonged to the age group of 40-59 years. More were males. Majority had come directly without any referral. This reveals the increased awareness about RGJAY among people. This scheme is more utilized by orange ration card holders than yellow card holders. In total surgeries majority utilized orthopaedics surgery. In total therapies majority utilized paediatric medical management. In conservative management majority utilized cardiology and burns. 

scholarly journals Clinical Symptoms, Pathogen Spectrum, Risk Factors and Antibiogram of Suspected Neonatal Sepsis Cases in Tertiary Care Hospital of Southern Part of Nepal: A Descriptive Cross-sectional Study

2020 ◽  
Vol 58 (232) ◽  
Author(s):  
Bijay Raj Pandit ◽  
Ashish Vyas
Keyword(s):  
Risk Factors ◽  
Mortality Rate ◽  
Neonatal Sepsis ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Cross Sectional Study ◽  
Care Hospital ◽  
Sectional Study ◽  
Neonatal Mortality Rate ◽  
Cross Sectional

Introduction: Neonatal mortality rate is highest in sub-Saharan Africa and Southern Asia region. The present study is undertaken to find out prevalence of neonatal sepsis, recognize bacterial pathogens, neonatal risk factors, major symptoms, and their antibiotic sensitivity pattern in neonates in tertiary care hospital in southern Nepal. Methods: A descriptive cross-sectional study was carried out in a tertiary care hospital from 2nd January 2017 to 20th February 2018 after approval (Ref: 125/2016-17). The sample size was calculated and convenience sampling was done. Data were collected from hospital records and microbiology laboratory and analyzed by Statistical Package for Social Sciences. Results: Out of 1200 clinically suspected cases, early-onset neonatal sepsis was seen in 290 (79.89%). A positive culture was seen in 363 (30.25%) where maximum bacterial growth was found in 254 (69.98%) males. Preterm gestational age was seen in 265 (73%), low birth weight 284 (78.23%), a vaginal delivery mode in 279 (76.90%), and delivery in hospital in 232 (63.91%). Likewise, Staphylococcus aureus in 229 (63.08%) was found maximum followed by Klebsiella pneumoniae in 48(13.22%). The major symptom observed was Respiratory distress in 245 (20.41%) while culture positive was seen in poor cry in 94 (53.10%). Mainly effective antibiotics against Gram-positive and gram-negative organisms were Linezolid in 250 (94%) and Imipenem in 46 (90.19%), whereas Penicillin-G in 254 (99.21%) and Ampicillin in 38 (94.74%) found resistance towards organisms respectively. Conclusions: The high prevalence of neonatal sepsis in our study reflects a huge challenge to reduce the neonatal mortality rate to 12 by 2030 of Sustainable Development Goals. Bacterial isolates exhibited higher resistance towards commonly used antibiotics.

scholarly journals Pattern of acne vulgaris in women, attending in a tertiary care hospital

2012 ◽  
Vol 18 (1) ◽  
pp. 18-23
Author(s):  
L Khondker ◽  
MM Rahman ◽  
MM Mahmud ◽  
MSI Khan ◽  
H Khan ◽  
...  
Keyword(s):  
Acne Vulgaris ◽  
Tertiary Care ◽  
Study Finding ◽  
Epidemiological Studies ◽  
Cross Sectional Study ◽  
Large Sample Size ◽  
Care Hospital ◽  
Cross Sectional ◽  
The Mean ◽  
Meta Analyses

A cross-sectional study was carried out for a period of one year in the outpatient department of Dermatology and Venereology, Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka, Bangladesh. Seventy female patients having acne vulgaris were selected. The study showed that the mean age of the cases was 22.43 with standard deviation 5.2 years and highest percentage of patients were in the age group 20-24 years (41.4%), highest percentage of patients was unmarried among the cases (74.3%) and proportion of secondary (35.7%) and higher secondary education (20%) were found to be high among the cases. The study showed that proportion of student (65.7%) and housewife (17.1%) were found to be high among the cases. The mean duration of disease was 62.6 months and all the patients had presented with comedones (blackheads and whiteheads). All the patients had acne in the face and it was found that 60% had moderate type acne. Considering the pattern of treatment received, 42.9% of the patients mentioned that they used topical ointment, 37.1% had received herbal medication and 25.7% had received systemic medication. To get an overall impression of the country regarding acne vulgaris, more integrated study is needed. This was a study on a limited number of cases. Future studies must include economical support, then large sample size could be ensured and study finding would be more reliable. There is a great need of epidemiological studies also, with sufficient follow-up, systematic reviews and meta-analyses on this issue. DOI: http://dx.doi.org/10.3329/jdnmch.v18i1.12234 J. Dhaka National Med. Coll. Hos. 2012; 18 (01): 18-23

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