scholarly journals Polypharmacy and Drug Interactions Study on Diabetic Patients of Geriatric Age Group at Rural Tertiary Care Hospital

2021 ◽  
Vol 13 (12) ◽  
pp. 39-43
Author(s):  
Shailesh Nagpure ◽  
Krishna Kela ◽  
Akshay C. Dahiwele
Author(s):  
Kuldeep Kumar Mewaram ◽  
Faraz Qurban Rajper ◽  
Khalida Unar ◽  
Mirza Tasawar Baig ◽  
Mirza Tasawar Baig ◽  
...  

Objective: The major theme of the research was to evaluate the frequency of diabetes mellitus patients with hepatitis C infection at tertiary care hospital of Sindh, Pakistan. Methodology: Descriptive cross sectional study was conducted at tertiary care hospital of Sindh, Pakistan for the period of 08 months; total 374 sample size was calculated by using Rao soft sample size calculator at the prevalence rate of 58.3% and confidence level 95% and margin of error 5%. Data was collected from patients of sero-positive HCV-RNA (Hepatitis C Virus-Ribose Nucleic Acid) visiting outpatient department or admitted at tertiary care hospital of Sindh, Pakistan and Informed consent form was also filled from all included subjects and data was analyzed by using SPSS software version 24.00. Results: From the 374 patients 209 were males and 165 females and all participants were divided in to various age groups as 15 patients were in the age group of 20-25 years, 67 patients were in 26-30 years, 48 patients included in 31-35 years and 109 patients were included in to age group of 36-40 years. Only 12 patients were included in the age group of 50 years and above. Total 164 (43.85%) were diabetic and 229 (61.22%) were diagnosed with Hepatitis C RNA (Ribose Nucleic Acid) positive. Patients had various range of HbA1c as 93 patients had range between 6-7mmol/dl. 107(28.60%) included in 7-9mmol/dl, 145(38.77%) included in 9-11mmol/dl and only 29 patients were having HbA1c (Glycated Hemoglobin) level above 11mmol/dl. Conclusion: It was concluded that there were increased number of diabetic patients with hepatitis C in worsening condition, so the proper programs should be conducted in order to reduce the complication of co-morbid disease.


Author(s):  
N. Vanitha Jyothi ◽  
Bharathi D. R. ◽  
Prakruthi G. M.

Objective: To evaluate the drug-drug interactions in General medicine, ICU and Emergency departments.Methods: It is a prospective-observational study. This study included hospital In-patients treated in General medicine, ICU and Emergency. Data were collected from the medical records of In-patients which includes patient’s demographic details, medical history, social history, treatment chart, status and drug-drug interaction is assessed by using Lexicompand Medscape and other tertiary resources and documented in a suitably designed data collection form.Results: A total of 250 subjects were enrolled in the study. The majority (23.6%) of cases were identified in the age group 51–60 y old. Higher rate of DDIs was identified in the male gender prescriptions. 70% moderate interactions, 33.6% Minor interactions, 6.4% serious interaction found in General medicine, ICU and Emergency departments.Conclusion: Polypharmacy, age and comorbid condition were took part major role in drug-drug interactions.


2017 ◽  
Vol 3 (3) ◽  
pp. 338-343
Author(s):  
Mohammad Didar Khan ◽  
Md. Ibrahim ◽  
Md. Mizanur Rahman Moghal ◽  
Dipti debnath ◽  
Asma Kabir ◽  
...  

Objective: The present epidemiological study was conducted with the objectives of providing an insight into the current use of antidiabetic medications to diabetics and hypertensive diabetics in urban areas and determining how the patient factors influence the prescribing of antidiabetic medications. Methodology: Data of patients of past two years were collected from Bangabandhu Sheikh Mujib Medical University (BSMMU) Hospital, Dhaka, Bangladesh. The details were entered in the structured patient profile form. Data were statistically analyzed using the Microsoft Excel 2007 software. Result: A total of 958 patient’s data were collected and analyzed of which 632 (65.97 %) were males and 326 (34.03 %) were females. These patients were further categorized based on their age. 330 patients (34.45 %) belonged to the age group 20 – 44 years, 504 (52.61 %) to the age group 45 – 65 years and 124 (12.94 %) to the age group 65 – 80 years. 684 (71.4%) patients out of the 958 patients studied were suffering from coexisting hypertension. Co-existing hypertension was found to be more prevalent in the age group 45 – 65 years (67.69%) and was found more in females (84.04%). Conclusion: Metformin was the oral hypoglycemic which was the highest prescribed. In hypertensive diabetics Metformin and Pioglitazone were most frequently prescribed drugs. Biguanides and Insulin were the most commonly prescribed antidiabetics. A combination of two or more drugs of different classes was prescribed to hypertensive diabetics. It is necessary to have an improved understanding of the etiology and pathophysiology of diabetes to focus on research efforts appropriately.


Author(s):  
Anjani Teja Ch ◽  
Ramesh babu K ◽  
Leela subramanyam S ◽  
Janani Y ◽  
Eswar Sai Kiran K ◽  
...  

The descriptive observational study was conducted over six months among inpatients of the orthopaedics department. The aim is to observe the prescribing pattern of drugs, to find out the percentage of analgesics given and most commonly prescribed analgesic, to compare the prescribed drugs whether they are in NLEM, WHO list and calculate DDD/100 Bed-days and to analyze the drugs for WHO prescribing drugs. A total of 250 patients were included in the study. Out of this, 168 were male, and 82 were female. Most of the patients were in the age group of 31-40[45 in number with 18%]. The most common condition was found to fracture [113 in number with 95.2%]. Commonly prescribed drugs were analgesics 447 with 26.76%. Among all the NSAID's, PCM was most commonly prescribed analgesic with 34.4%. The highest no, of drugs was found to be 4drugs/prescription with 24%. Monthly one analgesic was prescribed per prescription with 38.8%. Utilization of analgesics in term of DDD/100 Bed-days was 55.26; Drugs will be evaluated per prescription as per prescribing indicators of WHO was done, the average no. of drugs per prescription was found to be 0.45, percentage of drugs prescribed by generic name was found to be 13.3%, percentage of encounters with antibiotics prescribed were found to be 94.4%, In ratio percentage of drugs prescribed from the national list of essential medicine was found to be 92.6%. This study would help to facilitate better health care delivery.


2021 ◽  
Vol 19 (3) ◽  
pp. 23-29
Author(s):  
Yogita G Bavaskar ◽  

Background: Most of the countries including India have witnessed two or more waves of Covid 19 pandemic. The present study was conducted to compare the differences in clinico-demographic characteristics and outcomes of Covid 19 patients admitted in first and second wave of Covid 19 pandemic in a tertiary care hospital at Jalgaon, Maharashtra. Methods: A retrospective observational study was conducted at a tertiary care Dedicated Covid hospital for Covid 19 at Jalgaon, Maharashtra. All microbiologically proven corona positive patients were included in the study. The demographic records and clinical history was extracted from the case history sheets of the patients from first as well as second wave using standardized data collection form. Clinical outcome of the patients, i.e., development of complications, death or discharge was also recorded for each enrolled subject. Results: 3845 patients of Covid-19 admitted in the hospital during the first wave of epidemic and 2956 patients during second wave of the epidemic were included in the study. The mean age of patients admitted in the second wave was significantly lower as compared to first [48.77(15.31) years vs 50.23 (14.33) years, P<0.005]. There is increase in proportion of patients in the age group of < 15 years in second wave as compared to first wave (74/2956, 2.5% vs 52/3845, 1.3%). The number of patients requiring admission in ICU at the time of admission increased by 13% in second wave as compared to first wave. [827/2956 (28%) vs 577/3845(15%), P<0.0001]. More than half of the patients who got admitted for Covid 19 in first as well as second wave were having one or more comorbidities.But the proportion of the patients with previous co-morbities was significantly higher in second wave (1684/2956, 57% vs 1960/ 3845, 51%, P= 0.0004). The mortality was also higher in second wave (533/2956, 18.03% vs 541/3845, 14%, P=0.0004). Conclusions: The demographic, clinical characteristics and outcome of Covid 19 patients was different in first and second wave of pandemic with involvement of younger patients, increased rates of admission to ICU and more mortality in the second wave as compared to first wave of the pandemic.


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