Editorial Note

The novel coronavirus (COVID-19) pandemic has continued to wreak havoc on all people in the world regardless of their gender, creed, race, or class. It has also caused massive disruptions to all social, cultural, political, and economic activities and ruined the livelihoods of many people, especially in Africa, Asia, and Latin America. Despite the availability of vaccines, many countries are contending with insufficient supplies and low acceptance rates, leaving many people vulnerable to new waves of the pandemic. Governments across the world have been forced to renew some of the previous restrictions to flatten the curve of infections. Closing learning institutions, businesses, workplaces, recreational centres and activities and confining citizens to their homes has had an unprecedented negative effect on economies, markets, and supply chains, leading to skyrocketing rates of unemployment and poverty. The COVID-19 crisis has also altered the working conditions in most institutions of higher learning forcing many researchers, academics, and students to put their fieldwork and data collection on hold and thus, to delay writing their project reports. In a nutshell, many research projects have either been disrupted or suspended or stalled due to the pandemic.

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A Partnership of Un-Equals: Global South–North Research Collaborations in Higher Education Institutions

Modern Africa Politics History and Society ◽

10.26806/modafr.v8i2.343 ◽

2020 ◽

Vol 8 (2) ◽

pp. 9

Author(s):

Keneilwe Molosi-France ◽

Sinfree Makoni

Keyword(s):

Higher Education ◽

Global South ◽

Higher Learning ◽

Research Partnerships ◽

The North ◽

Research Collaborations ◽

Institutions Of Higher Learning ◽

The World ◽

Learning Institutions ◽

Research Resources

With the realisation that institutions of higher learning may play a powerful role in transforming the world, research partnerships between institutions in the Global South and North have gained popularity. These partnerships are meant to empower and strengthen the contribution of higher learning institutions and bridge the North/South knowledge divide. Considering the limited access to research resources in the Global South, it is anticipated that these partnerships will create research opportunities for scholars. However, while it can be acknowledged that the research partnerships can be of benefit to African institutions and economy, there are practical challenges that limit the success of most research partnerships. Using the authors’s experience this article explores and describes issues that surround research collaborations between institutions of higher learning in the Global South and North.

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Disaster Management Preparedness in the Education Sector in Kenya – A Case of the COVID-19 Pandemic.

Editon Consortium Journal of Educational Management and Leadership ◽

10.51317/ecjeml.v1i1.192 ◽

2020 ◽

Vol 1 (1) ◽

pp. 86-96

Author(s):

Prof. Fr. Stephen Mbugua Ngari; Stephen W Ndung’u

Keyword(s):

Disaster Management ◽

Higher Learning ◽

Middle Level ◽

Education Sector ◽

The Novel ◽

Institutions Of Higher Learning ◽

E Learning ◽

Development Goals ◽

The One ◽

Novel Coronavirus

This study examined the disaster management preparedness in the education sector in Kenya, with a focus on the COVID-19 pandemic period. The study adopted destktop literature review for data collection. The collected data pertains e-learning in Kenya and in other countries during the time of the novel coronavirus pandemic. Notably, the education sector, like in many other countries, seeks to actualise the Millennium Development Goals (MDGs) in line with the United Nations and the Education for All (EFA) movement lead by UNESCO (MacEwen, et al., 2011). Examples of these events are; accidents such as the one evident in Kakamega Primary School where the school closed for about two weeks (Daily Nation, 2020), attack by militia groups as was the case of Garissa University in 2015, intercommunity wars that lead to displacements, famine, and fires. These disasters and events, whenever they strike, have led to the closure of affected institutions of learning to pave the way for interventions. Garissa University is a leading example since it had to close for about nine months in 2015-2016 (BBC, 2016). In Kenya, disasters and other events disrupt the progress towards achieving MDGs and EFA time to time, and that was the inspiration for this study. The study concludes that disasters like nature patterns, militia groups, electricity faults, and those instigated by learners can derail learning in education and cause loss of lives. As such, online learning comes in handy to lessen such disasters. The possibility of such learning model has been tested and proved during COVID-19 pandemic and it has been successful in many institutions of higher learning and middle level colleges.

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The Role of Moral Education on the Dress Code in the Higher Learning Institution

Sains Insani ◽

10.33102/sainsinsani.vol1no1.2 ◽

2016 ◽

Vol 1 (1) ◽

pp. 10-14

Author(s):

Ira Meilita Ibrahim ◽

Taufik A. Latif ◽

Afi Roshezry Abu Bakar ◽

Muthualagan Thangavelu

Keyword(s):

Moral Education ◽

Private University ◽

Public University ◽

Higher Learning ◽

Private Institutions ◽

Dress Code ◽

Institutions Of Higher Learning ◽

The World ◽

Definition Of

The advancement of European dress to the rest of the world was linked to the definition of civilization as “a stage of social development considered to be more advanced” and “polite and good-mannered”. The widespread of their fashion style in the 19th and 20th centuries influenced the way the rest of the world attire. The fashion trend and dressing style thus change the purpose of dressing through time. The dressing style in campuses especially in private institutions of higher learning is under particular scrutiny, as it is often said to be inappropriate for a learning environment. This study looked at the importance of moral education, and its role in implementing the dress code for students among university students especially between two types of university i.e. public university and private university. It looked on the dressing style of students, both male and female, and the factors that lead to their dressing pattern which is common among students. This study also advocated the students’ understanding of the content of dress codes in their learning institution and the role played by moral education in regard to dress code. The overall study highlighted students’ perception towards the implementation of the dress code and punishment in their learning institution. The methodologies used to carry out this study are questionnaires and interviews. This study will therefore ascertain the important of dress code among students at higher learning institution and the role of moral education in cultivating values in order to dress properly or decently. Key Words: moral education, dress code, higher learning institution, civilization.

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Comparative docking of SARS-CoV-2 receptors antagonists from repurposing drugs

10.26434/chemrxiv.12044538.v4 ◽

2020 ◽

Author(s):

Micael Davi Lima de Oliveira ◽

Kelson Mota Teixeira de Oliveira

Keyword(s):

World Health Organisation ◽

World Health ◽

Lung Cells ◽

The Novel ◽

High Modulation ◽

Main Protease ◽

The World ◽

Novel Coronavirus ◽

Viral Receptors ◽

Theoretical Results

According to the World Health Organisation, until 16 June, 2020, the number of confirmed and notified cases of COVID-19 has already exceeded 7.9 million with approximately 434 thousand deaths worldwide. This research aimed to find repurposing antagonists, that may inhibit the activity of the main protease (Mpro) of the SARS-CoV-2 virus, as well as partially modulate the ACE2 receptors largely found in lung cells, and reduce viral replication by inhibiting Nsp12 RNA polymerase. Docking molecular simulations were performed among a total of 60 structures, most of all, published in the literature against the novel coronavirus. The theoretical results indicated that, in comparative terms, paritaprevir, ivermectin, ledipasvir, and simeprevir, are among the most theoretical promising drugs in remission of symptoms from the disease. Furthermore, also corroborate indinavir to the high modulation in viral receptors. The second group of promising drugs includes remdesivir and azithromycin. The repurposing drugs HCQ and chloroquine were not effective in comparative terms to other drugs, as monotherapies, against SARS-CoV-2 infection.

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Association and treatment of diabetes in patients affected by Covid-19

International Journal of Research in Pharmaceutical Sciences ◽

10.26452/ijrps.v11ispl1.3591 ◽

2020 ◽

Vol 11 (SPL1) ◽

pp. 1198-1201

Author(s):

Syed Yasir Afaque

Keyword(s):

Diabetes Mellitus ◽

Prognostic Value ◽

Heart Diseases ◽

The Novel ◽

The World ◽

Treatment Of Diabetes ◽

Coronavirus Infection ◽

Composite Outcomes ◽

Novel Coronavirus ◽

The Impact

In December 2019, a unique coronavirus infection, SARS-CoV-2, was first identified in the province of Wuhan in China. Since then, it spread rapidly all over the world and has been responsible for a large number of morbidity and mortality among humans. According to a latest study, Diabetes mellitus, heart diseases, Hypertension etc. are being considered important risk factors for the development of this infection and is also associated with unfavorable outcomes in these patients. There is little evidence concerning the trail back of these patients possibly because of a small number of participants and people who experienced primary composite outcomes (such as admission in the ICU, usage of machine-driven ventilation or even fatality of these patients). Until now, there are no academic findings that have proven independent prognostic value of diabetes on death in the novel Coronavirus patients. However, there are several conjectures linking Diabetes with the impact as well as progression of COVID-19 in these patients. The aim of this review is to acknowledge about the association amongst Diabetes and the novel Coronavirus and the result of the infection in such patients.

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Synthetic and semi-synthetic drugs as promising therapeutic option for the treatment of COVID-19

Mini-Reviews in Medicinal Chemistry ◽

10.2174/1389557520666201204162103 ◽

2020 ◽

Vol 20 ◽

Author(s):

Ekta Shirbhate ◽

Preeti Patel ◽

Vijay K Patel ◽

Ravichandran Veerasamy ◽

Prabodh C Sharma ◽

...

Keyword(s):

Therapeutic Option ◽

Antiviral Treatment ◽

The Novel ◽

Clinical Experiences ◽

Synthetic Compounds ◽

Synthetic Drugs ◽

Global Pandemic ◽

The World ◽

Novel Coronavirus

: The novel coronavirus disease-19 (COVID-19), a global pandemic that emerged from Wuhan, China has today travelled all around the world, so far 216 countries or territories with 21,732,472 people infected and 770,866 deaths globally (as per WHO COVID-19 update dated August 18, 2020). Continuous efforts are being made to repurpose the existing drugs and develop vaccines for combating this infection. Despite, to date, no certified antiviral treatment or vaccine prevails. Although, few candidates have displayed their efficacy in in vitro studies and are being repurposed for COVID-19 treatment. This article summarizes synthetic and semi-synthetic compounds displaying potent activity in their clinical experiences or studies against COVID-19 and also focuses on mode of action of drugs being repositioned against COVID-19.

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Native Approaches to Decolonising Education in Institutions of Higher Learning

The Australian Journal of Indigenous Education ◽

10.1017/s1326011100001629 ◽

2000 ◽

Vol 28 (2) ◽

pp. 28-34 ◽

Cited By ~ 8

Author(s):

Polly Walke

Keyword(s):

Higher Education ◽

Indigenous Peoples ◽

Higher Learning ◽

Native Peoples ◽

Institutions Of Higher Learning ◽

The World

A growing number of Native scholars are involved in decolonising higher education through a range of processes designed to create space for Indigenous realities and Indigenous ways of managing knowledge. Basing their educational approaches on Indigenous ontologies and epistemologies, they are developing Indigenist approaches within higher education. Ward Churchill (1996:509), Cherokee scholar, explains that an Indigenist scholar is one who:Takes the rights of indigenous peoples as the highest priority …who draws on the traditions – the bodies of knowledge and corresponding codes of value – evolved over many thousands of years by native peoples the world over.

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An outline of SARS-CoV-2 pathogenesis and the complement cascade of immune system

Bulletin of the National Research Centre ◽

10.1186/s42269-021-00582-2 ◽

2021 ◽

Vol 45 (1) ◽

Author(s):

Padmalochan Hembram

Keyword(s):

Immune System ◽

Dark Side ◽

Main Body ◽

The Novel ◽

Transmission Chain ◽

The World ◽

Therapeutic Molecules ◽

Rapid Transmission ◽

Novel Coronavirus ◽

Near Future

Abstract Background Coronavirus disease 19 is a viral infection caused by a novel coronavirus, SARS-CoV-2. It was first notified in Wuhan, China, is now spread into numerous part of the world. Thus, the world needs urgent support and encouragement to develop a vaccine or antiviral treatments to combat the atrocious outbreak. Main body of the abstract The origin of this virus is yet unknown; however, rapid transmission from human-to-human “Anthroponosis” has widely confirmed. The world is witnessing a continuous hike in SARS-CoV-2 infection. In light of the outbreak of coronavirus disease 19, we have aimed to highlight the basic and vital information about the novel coronavirus. We provide an overview of SARS-CoV-2 transmission, timeline and its pathophysiological properties which would be an aid for the development of therapeutic molecules and antiviral drugs. Immune system plays a crucial role in virus infection in order to control but may have dark side when becomes uncontrollable. The host and SARS-CoV-2 interaction describe how the virus exploits host machinery and how overactive host immune response can cause disease severity also addressed in this review. Short conclusion Safe and effective vaccines may be the game-changing tools, but in the near future wearing mask, washing hands at regular intervals, avoiding crowed, maintaining physical distancing and hygienic surrounding, must be good practices to reduce and break the transmission chain. Still, research is ongoing not only on how vaccines protect against disease, but also against infection and transmission.

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COVID-19 Vaccination: From Interesting Agent to the Patient

Vaccines ◽

10.3390/vaccines9020120 ◽

2021 ◽

Vol 9 (2) ◽

pp. 120

Author(s):

Anis Daou

Keyword(s):

Central Nervous System ◽

Nervous System ◽

Gastrointestinal Tract ◽

Circulatory System ◽

The Novel ◽

Lead Compound ◽

Fda Approval ◽

The World ◽

The Central Nervous System ◽

Novel Coronavirus

The vaccination for the novel Coronavirus (COVID-19) is undergoing its final stages of analysis and testing. It is an impressive feat under the circumstances that we are on the verge of a potential breakthrough vaccination. This will help reduce the stress for millions of people around the globe, helping to restore worldwide normalcy. In this review, the analysis looks into how the new branch of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) came into the forefront of the world like a pandemic. This review will break down the details of what COVID-19 is, the viral family it belongs to and its background of how this family of viruses alters bodily functions by attacking vital human respiratory organs, the circulatory system, the central nervous system and the gastrointestinal tract. This review also looks at the process a new drug analogue undergoes, from (i) being a promising lead compound to (ii) being released into the market, from the drug development and discovery stage right through to FDA approval and aftermarket research. This review also addresses viable reasoning as to why the SARS-CoV-2 vaccine may have taken much less time than normal in order for it to be released for use.

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