scholarly journals HYGIENIC EVALUATION OF INSECTICIDES CONTENT DYNAMICS IN PLANTS AFTER APPLICATION ON SOYA CROPS

2019 ◽  
Vol 15 (3-4) ◽  
pp. 69-75
Author(s):  
S.T. Omelchuk ◽  
A.V. Blagaya ◽  
M.V. Kondratyuk ◽  
T.V. Hyrenko

Relevance. Taking into account the widespread application of plant protection products in soybean cultivation, there is a need for research aimed at hygienic evaluation of the potential danger of soybean crop contamination after pesticide and in particular insecticides application. Objective of the study is a hygienic evaluation of insecticides content dynamics in plants after application on soya crops. Materials and methods. Materials – active ingredients of the studied insecticidal preparations, soya plants (verdurous mass, beans and seeds). Full-scale in-field hygienic experiment, high-performance liquid chromatography, gas-liquid chromatography, statistical methods were used in the study. Results. The highest concentration of active substances was determined in green plants, if processing had been performed at an early stage of plant formation (acetamipride – 0.63 mg/kg, fenproximate – 0.41 mg/kg, thiamethoxam – 0.21 mg/kg). In the case of twice repeated applications, the largest amount of pesticides was determined in beans and seeds (alpha-cypermethrin – 0.51 mg/kg, chlorpyrifos, tebufenpyrad – 0.35 mg/kg). As the culture ripened and the formation of beans and seeds took place, the content of active substances gradually decreased and after 20-25 days residues were found at or below the limit of determination for the corresponding methods. Conclusions. The redidues of alpha-cypermethrin, bifenthrin, chlorpyrifos cypermethrin, tebufenpyrad, phenpyroximate, acetamiprid, thiamethoxam in plants, beans and soybean seeds gradually decreased and did not exceed established hygienic standards by the harvesting period in field studies. It is proved that if to follow the established hygienic and agrotechnical regulations for its application, the studied insecticides dissipate or decompose in crop plants during one vegetative season and do not pose a potential risk to the health of consumers.

2021 ◽  
Vol 350 ◽  
pp. S237
Author(s):  
M. Karaca ◽  
B. Fischer ◽  
C.T. Willenbockel ◽  
P. Marx-Stoelting ◽  
D. Bloch

Author(s):  
Anna A. Romanyuk ◽  
Dmitry V. Moiseev

Objective: generalization and analysis of scientific data on the component composition, pharmacological properties and standardization of senna leaves. Materials and methods. The article provides an overview of scientific publications in the journals of the search platforms Scopus and PubMed, as well as the databases of the Russian Science Citation Index. The analysis of the range of herbal medicinal products was carried out according to the data of the State Registers of Medicines of the Republic of Belarus, the Russian Federation and the Republic of Kazakhstan using content analysis, comparison and generalization of data. Results. In addition to the laxative effect, determined by the presence of anthracene derivatives in senna leaves, the complex of their biologically active substances has antimicrobial, hypoglycemic, antioxidant, antifungal and antitumor effects. Also, the chemical composition of the plant is represented by fatty acids, triglycerides, flavonoids, macro- and microelements. The analysis of medicinal herbal preparations based on senna leaves registered in the Russian Federation, the Republic of Belarus and the Republic of Kazakhstan has been carried out. The differences in the methods of their standardization, given in the normative documentation on quality, have been revealed. The scientific experience of using the method of high performance liquid chromatography for the determination of anthracene derivatives in senna leaves is generalized. Conclusion. The complex of biologically active substances of senna leaves exhibits various pharmacological effects, which, possibly, will expand the range of combined preparations based on them. The use of a modern and selective method of high-performance liquid chromatography in the analysis of senna leaves is a very promising direction in the field of standardization of this type of medicinal plant material.


2021 ◽  
Vol 3 ◽  
Author(s):  
Rositsa Serafimova ◽  
Tamara Coja ◽  
George E. N. Kass

The safety assessment of chemicals added or found in food has traditionally made use of data from in vivo studies performed on experimental animals. The nature and amount of data required to carry out a risk assessment is generally stipulated either in the different food legislations or in sectoral guidance documents. However, there are still cases where no or only limited experimental data are available or not specified by law, for example for contaminants or for some minor metabolites from active substances in plant protection products. For such cases, the Threshold of Toxicological Concern (TTC) can be applied. This review explores the use of the TTC approach in food safety in the European Union, in relation to the different food sectors, legal requirements and future opportunities.


1977 ◽  
Vol 23 (12) ◽  
pp. 2283-2287 ◽  
Author(s):  
G W Mihaly ◽  
J A Phillips ◽  
W J Louis ◽  
F J Vajda

Abstract We describe a modified high-performance liquid-chromatographic method for the simultaneous analysis of carbamazepine andits biologically active metabolite, carbamazepine-10, 11-epoxide. Concentrations of both these compounds in the plasma of 35 epileptic patients receiving chronic carbamazepine therapy are presented. Concentrations of carbamazepine in plasma were related to those of carbamazepine-10, 11-epoxide (r - 0.495, P less than 0.05). Total daily doses of carbamazepine were better correlated with plasma concentrations of carbamazepine-10, 11-epoxide (r = 0.714, P less than 0.001) than of carbamazepine (r = 0.269, P greater than 0.05). Close correlations were found between results of the three assay procedures we used to measure plasma carbamazepine concentrations: high-performance liquid chromatography, gas-liquid chromatography, and enzyme immunoassay. Correlation coefficients exceeded 0.97 and regression slopes were near unity, indicating that all three procedures were individually specific for the quantification of plasma carbamazepine.


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