scholarly journals Laboratory preparation and quality control of medicinal composition based on nanosilica and polymethylsiloxane

2018 ◽  
pp. 70-76
Author(s):  
S. I. Chornoknyzhnyj ◽  
O. M. Cheplyaka ◽  
I. I. Gerashchenko
Keyword(s):  
Quality Control ◽  
Ball Mill ◽  
Chemical Methods ◽  
Adsorption Activity ◽  
Step Process ◽  
Absorption Spectrophotometry ◽  
Powder Composition ◽  
Factory Production ◽  
Treatment Of Wounds ◽  
Total Adsorption

The prepared ex tempore adsorption composition which consists of nanosilica, polymethylsiloxane, metronidazole and decamethoxin serves as an effective mean for the topical treatment of wounds. The aim of the study was the development of an optimal pathway for laboratory manufacturing and quality control of this drug. We used the method of mechanochemical treatment in a ball mill, chemical methods of identification, absorption spectrophotometry in the IR, UV and visible regions, and the method of sowing on plates to determine microbiological purity. To obtain a uniform powder composition capable wettable in aqueous medium, there is provided a three-step process comprising mechanosorption of metronidazole on nanosilica and, accordingly, of decametoxin – at polymethylsiloxane. The conditions of identification tests and assay of the ingredients of the composition were сlarified and optimized. It was found that microbiological purity of the composition does not yield to known drugs which intended for topical application. Total adsorption activity of the nanocomposition is stated on the absorption of methylene blue, special protein adsorption activity – on the binding of gelatin. The obtained results may be useful for the organization of the recent pharmacy and the future factory production of proposed nanocomposition.

Advantages and Disadvantages of Nephelometric Measurement of Serum Lipids

1974 ◽  
Vol 20 (4) ◽  
pp. 502-504 ◽  
Author(s):  
Daniel M Baer
Keyword(s):  
Quality Control ◽  
Serum Lipids ◽  
Serum Triglyceride ◽  
Chemical Methods ◽  
Unstable Material ◽  
Advantages And Disadvantages ◽  
Control Procedures ◽  
Frequent Problem

Abstract Several technical difficulties diminish the usefulness of serum triglyceride estimation by the method of Stone and Thorp [Clin. Chim. Acta 14, 812 (1966)]. An artificial and somewhat unstable material is used in the standardization. Falsely elevated readings caused by scratched cuvettes are a frequent problem. Conventional quality-control procedures cannot be used because stable preparations are not available. Specimen stability is a greater problem than with conventional chemical methods. In spite of these difficulties, the method can be useful, if its limitations are recognized, in measurements made on nonfasting individuals.

scholarly journals Pengendalian Mutu Produk Semen Melalui Pendekatan Statistical Quality Control (SQC) (Studi Kasus Di PT. Semen Baturaja)

2019 ◽  
Vol 4 (1) ◽  
pp. 24
Author(s):  
Danil Saputra ◽  
Renilaili Renilaili
Keyword(s):  
Quality Control ◽  
Ball Mill ◽  
Tube Mill ◽  
Statistical Quality Control ◽  
Statistical Quality ◽  
Control Diagram

PT. Semen Baturaja (Persero) tbk merupakan perusahaan yang bergerak dibidang produksi semen di sumatera selatan. Produk yang diproduksi berupa produk semen OPC dan PCC. Suatu produk tentunya tidak terlepas dari permasalahan produk tidak sesuai standar kualitas produk. Tujuan dari penelitian ini adalah untuk mengetahui upaya pengendalian kualitas dan faktor – faktor apa saja yang menyebabkan ketidaksesuaian kualitas produk yang diproduksi oleh PT. Semen Baturaja, pengukuran produk tidak sesuai standar berdasarkan lima parameter pengukuran kualitas, yakni Blaine, Residu 45µm, SO3, FCaO dan LOI, dengan menggunakan metode Statistical Quality Control, diagram Pareto dan Diagram sebab akibat, diperoleh hasil analisis yakni, parameter Residu 45µm dan Blaine memiliki jumlah ketidaksesuaian yang paling dominan yakni 71,9% dan 23,7%, yang berarti Penyebab terbesar ketidaksesuaian produk adalah mesin Tube Mill, dimana volume ball mill <80% yang mengakibatkan proses penggilingan material menjadi tidak optimal

Quality control in urinary stone analysis: results of 44 ring trials (1980–2001)

2005 ◽  
Vol 43 (3) ◽  
Author(s):  
Albrecht Hesse ◽  
Rolf Kruse ◽  
Wolf-Jochen Geilenkeuser ◽  
Matthias Schmidt
Keyword(s):  
Quality Control ◽  
Infrared Spectroscopy ◽  
Urinary Stone ◽  
Error Rates ◽  
The Body ◽  
X Ray Diffraction ◽  
Stone Analysis ◽  
Chemical Methods ◽  
X Ray ◽  
Pure Substances

AbstractUrinary stone analysis is the most important diagnostic step after stone removal from the body. The methods employed for these analyses are based on diverse analytical principles. Chemical methods are used for detecting individual ions. Infrared spectroscopy is used for examining molecular structures, and X-ray diffraction for determination of the crystalline structure of a substance. Since 1980, a twice-yearly ring trials quality control survey has been on offer to examine the quality of urinary stone analyses. A summary of the results of 44 ring trials (1980–2001) has been compiled for individual pure substances and binary (two-component) mixtures. On average, 100 laboratories have participated in these ring trials. Initially, over 80% of the participants carried out their analyses using chemical methods. In 2001, this figure decreased to a mere 13%. In contrast, a progressive increase in the use of infrared spectroscopy was observed, up to 79% of all participants employed this method. X-Ray diffraction was only employed in a small number of specialised laboratories (5–9%). The chemical methods produced a very high proportion of errors (6.5–94%) with both the pure substances and binary mixtures, whereas high error rates for infrared spectroscopy and X-ray diffraction were confined to individual substances only. Due to the poor results in the ring trials, the majority of laboratories stopped using chemical analysis, which is now considered to be obsolete. Regarding mixtures, error rates of over 10% also occurred with infrared spectroscopy and X-ray diffraction. Ring trials are indispensable for the quality management of urinary stone analysis.

scholarly journals The Research of Thermaland Chemical Treatment Methods Influence on Sorption Properties of Peat Materials

2021 ◽  
Vol 132 (1) ◽  
pp. 19-24
Author(s):  
T. S. Smirnova ◽  
◽  
V. A. Shirokov ◽  
A. A. Zaporozhskaya ◽  
◽  
...  
Keyword(s):  
Oil Spill ◽  
Chemical Treatment ◽  
Sorption Properties ◽  
Russian Regions ◽  
Chemical Methods ◽  
Processing Efficiency ◽  
Adsorption Activity ◽  
Environmental Friendly ◽  
Materials Research ◽  
Oil Spill Response

The article is about of the processing of peat material from different Russian regions as an environmental-friendly andan available sorbentsfor the oil spill response. The paper presents the results of peat materials research. Peat materialswere processed by thermal and chemical methods. Oil intensity, adsorption activity and hydrophobicity were investigatedas indicators of the processing efficiency. The dataanalysis obtained with the interpretation of the results and prospects for further work in this wayare given in the article.

Gahnite compositions compared

1984 ◽  
Vol 48 (348) ◽  
pp. 425-429 ◽  
Author(s):  
Richard A. Batchelor ◽  
Judith A. Kinnaird
Keyword(s):  
Spinel Structure ◽  
Atomic Absorption Spectrophotometry ◽  
Unit Cell Dimension ◽  
Compositional Heterogeneity ◽  
X Ray Diffraction ◽  
Chemical Methods ◽  
X Ray ◽  
Absorption Spectrophotometry ◽  
The World ◽  
Wet Chemical

Abstract Blue-coloured gem-quality spinel from Nigeria was analysed by wet chemical methods (using atomic absorption spectrophotometry) and investigated by X-ray diffraction. The results showed it to be gahnite (unit cell dimension a=8.091±0.003 Å) containing 36.7% ZnO, 3.58% FeO, and 0.12% MgO. The spinel has an RI of 1.79 and density between 4.4 and 4.59. Broadening of the n[111] XRD reflections indicates a measure of compositional heterogeneity. The gahnite analyses were compared with compositions of zinc spinels from other parts of the world. The analyses cluster into two distinct groups, Mg-rich spinels of metamorphic origin and Mg-poor spinels (including the Nigerian gahnite) with igneous affinities. Diadochy seems to operate within the zinc spinel structure between (Zn + Mn) and (Fe + Mg).

scholarly journals Impact of some pyrrolidinium ionic liquids on copper dissolution behavior in acidic environment: experimental, morphological and theoretical insights

RSC Advances ◽  
2019 ◽  
Vol 9 (36) ◽  
pp. 20760-20777 ◽  
Author(s):  
Emad E. El-Katori ◽  
Ashraf S. Abousalem
Keyword(s):  
Weight Loss ◽  
Ionic Liquids ◽  
Electrochemical Techniques ◽  
Dissolution Behavior ◽  
Acidic Environment ◽  
Chemical Methods ◽  
Adsorption Activity ◽  
Copper Dissolution

The inhibitive and adsorption activity of some pyrrolidinium ionic liquids (ILs) for the dissolution of copper in 1 M HNO3 solution was tested using chemical methods such as weight loss and electrochemical techniques.

Quality Control of Steel Using Clock and Chart Recording Photoelectric Spectrometers

1962 ◽  
Vol 16 (2) ◽  
pp. 29-32 ◽  
Author(s):  
Joseph F. Woodruff ◽  
Arba H. Thomas
Keyword(s):  
Quality Control ◽  
Production Control ◽  
Analytical Data ◽  
Instrumental Analysis ◽  
Analysis Program ◽  
Chemical Methods ◽  
Steel Corporation ◽  
Chart Recording

A check analysis program initiated over twenty-five years ago is used to evaluate the performance of emission photoelectric spectrometers in five production control laboratories of the Armco Steel Corporation. For comparison, evaluation of analyses using conventional chemical methods by these same laboratories prior to instrumental analysis is also made The paper describes the check analysis program and presents analytical data used to evaluate the accuracies of the two types of photoelectric spectrometers and the conventional chemical methods used by the production laboratories.

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