scholarly journals EFFICACY OF PHENYLEPHRINE OVER EPHEDRINE IN CONTROLLING FALL OF BLOOD PRESSURE: A CROSS SECTIONAL STUDY IN PATIENTS UNDERGOING LOWER SEGMENT CAESAREAN SECTION

Author(s):  
Keshav Saran Agrawal ◽  
Aruna Mahanta

Background: most of the lower segment caesarean sections are done under spinal anesthesia and in more that 80% of the cases, maternal fall in blood pressure can be observed intraoperatively. Throughout history many vasopressor drugs have been evaluated for the treatment. Aim: our research was conducted to compare the effect of phenylephrine with ephedrine given for the prophylaxis of prevention of intraoperative fall in blood pressure in females who are undergoing LSCS. Materials and Methods: a total of 100 cases were considered for our study and were randomly distributed in two groups. Group A cases were administered Phenylephrine while ephedrine was given to group B cases just after spinal anesthesia. Results: most of our study subjects were in the age group of 21-25 years who were in the range of 51-55 kgs. Spinal anesthesia was given by using bupivacaine & block level was checked at 2 & 5 mins. Phenylephrine was found to be superior in control of fall in blood pressure as more than 90% of the cases were brought back to their preoperative levels in less than 4 mins after spinal anesthesia. Whereas in group B, ephedrine took much more time of around 10 mins for control of BP. Conclusion: with proper monitoring of heart rate, phenylephrine is superior to ephedrine in controlling the fall in blood pressure. Keywords: Ephedrine, Phenylephrine, Hypotension, Bradycardia.

1970 ◽  
Vol 10 (4) ◽  
pp. 266-268
Author(s):  
MS Ahmed ◽  
H Rahman ◽  
ZG Ara ◽  
SZ Sultana ◽  
M Rahman

Aims: The morphological study was aimed to finedout the ovarian weight in dif ferent age group in Bangladeshi people to increase the knowledge regarding weight variation in our population. Subject & Methods: This cross - sectional study was carried out on Sixty two postmortem tissue contain ovary and fallopian tube along with surrounding structures were collected from 62- female cadaver of different age group by block dissection and fixed in 10% formal saline solution. Gross and fine dissections were carried out to see the morphological parameter of weight of the ovary in different age groups. In the present study, findings were compared with findings of the other researchers. Results: Maximum mean weight of the right ovary is found in this study in group C (46-80) years is 5.78gm and minimum weight is found in group A (2-13 years ) is 3.36gm .But incase left ovary Maximum in group B(14-45)years is 5.01 and minimum group a (2-13)is 2.72gm. statistatical analysis significant different between two groups was calculated by using students "T"Test. In the present study it is observed that the weight of the ovary is not equal on both side of same individual. Key words: ovary,morphology; weight DOI: http://dx.doi.org/10.3329/bjms.v10i4.9498 BJMS 2011; 10 (4): 266-268


2013 ◽  
Vol 25 (1) ◽  
pp. 28-31
Author(s):  
N Habib ◽  
M Rashid ◽  
USN Begum ◽  
N Ahter ◽  
D Akhter

This cross-sectional study was carried out to assess blood pressure parameters among adult male smokers and smokeless tobacco users. For this purpose, 105 male respondents were selected. They were divided into two groups; Group A-consisting of 30 were smokeless tobacco users and group B consisting of 75 smoker patients The participants were selected from medicine outdoor of Dhaka Medical College Hospital. In this study, the mean (±SD) of systolic blood pressure were 154.50±26.793 mm of Hg in Group A and 151.67±19.248 mm of Hg in group B respectively. Statistical analysis was done by unpaired‘t’ test, there were no statistical significant differences (P>0.05) of systolic blood pressure between Group A and Group B. The mean (±SD) of diastolic blood pressure were 96.67±10.933 mm of Hg in Group A and 86.47±14.745 mm of Hg in group B respectively. The mean (± SD) of diastolic blood pressure were significantly higher (P<0.05) in Group A than Group B. DOI: http://dx.doi.org/10.3329/medtoday.v25i1.16066 Medicine Today 2013 Vol.25(1): 28-31


2018 ◽  
Vol 4 (1) ◽  
pp. 8-11
Author(s):  
Rumi Farhad Ara ◽  
Jahangir Alam

Background: Clinical profiles of the teenage pregnancy are diffident from the adult pregnancy.Objective: The purpose of the present study was to compare the clinical profiles of teenage and adult pregnancy.Methodology: This comparative cross sectional study was conducted in the Department of Obstetrics and Gynecology at Dhaka Medical College & Hospital, Dhaka, Bangladesh and Sir Salimullah Medical College & Mitford Hospital, Dhaka, Bangladesh from April to July 1999 for a period of four (4) months. The teenage mothers with the age group of 11 to 19 years who were admitted in the study period were selected as group A and pregnant women with the age group of more than 19 years were selected as group B. All the clinical profiles of these two groups were recorded after admission of these pregnant women.Result: Among the primigravid patients, 50 cases with the age group 11 to 19 years were in the group A and 50 patients with the age group more than 19 years were in group B were selected. Among teens, 68 percent have no antenatal cheek-up. Moderate anaemia was more frequently found in the group A than group B which was 14(28.0%) and 9(18.0%) cases respectively. Moderate oedema was more frequently found in the group A than group B which was 16(32.0%) and 12(24.0%) cases respectively. In teenage group 32(64.0%) cases were without hypertension, whereas 44(88.0%) cases were in adult group.Conclusion: In conclusion anaemia and oedema are more commonly found in the teen pregnancy.Journal of National Institute of Neurosciences Bangladesh, 2018;4(1): 8-11


2020 ◽  
Vol 27 (06) ◽  
pp. 1275-1279
Author(s):  
Shumyala Maqbool ◽  
Mohsin Riaz Askri ◽  
Sahir Shafique ◽  
Kausar Abbas Shah

Objectives: To observe the frequency of spinal hypotension in patients undergoing Elective Lower Segment Caesarean Section receiving pre-operative preload compared with intramuscular ephedrine. Study Design: Cross Sectional study. Setting: Department of Anesthesia, Independent Medical College, Faisalabad. Period: July 1st 2018 to December 31st 2018. Material & Methods: This study included fifty-two female patients, aged 20-35 years, undergoing elective C/section under spinal anesthesia with ASA physical status I & II, pre-operatively preloaded and given prophylactic intramuscular ephedrine. Hemodynamic changes were recorded in both groups after receiving spinal anesthesia. Results: Compared with the prophylactic ephedrine group, frequency of Post spinal hypotension was higher significantly in pre-load group (p=0.019). Conclusion: It has been concluded that there is the use of prophylactic intra muscular ephedrine is associated with low incidence of post spinal hypotension.


Author(s):  
Rosalía Romero-Tena ◽  
Carmen Llorente-Cejudo ◽  
María Puig-Gutiérrez ◽  
Raquel Barragán-Sánchez

Without having a reaction time, the pandemic has caused an unprecedented transformation in universities around the world, leading to a revolution from structured models anchored in the conception of transmission of training towards a teaching approach-learning saved thanks to the incorporation of technology. This study aims to verify whether the pandemic situation has influenced the digital competence self-perception of students. Comparing two groups during the academic years 2019/2020 and 2020/2021, the instrument used is the questionnaire for digital competence “DigCompEdu Check-In” for future teachers. After the educational intervention, group A (before COVID-19) presented higher self-perceptions of competence than group B (during COVID-19); the pandemic situation caused by COVID-19 has negatively influenced students’ self-perception of their digital skills in the pretest in the different dimensions under study. Before receiving the training, the group that did not experience the pandemic enjoyed a higher self-perception of their competencies than the group that experienced the pandemic. The data obtained indicate that the difference exists, and that it is statistically significant, and may be a consequence of the clear relationship between self-perception and the way in which students face reality through their personal and subjective vision.


2021 ◽  
pp. e20210156
Author(s):  
Maria Montes de Oca1 ◽  
Maria Victorina Lopez Varela2 ◽  
Ana Maria B. Menezes3 ◽  
Fernando C. Wehrmeister3 ◽  
Larissa Ramirez4 ◽  
...  

Objective: To assess the frequency and severity of 24-hour respiratory symptoms according to COPD GOLD-ABCD classification (2017-version), the distribution of the patients with COPD into GOLD categories using mMRC (=2) or CAT (=10) scores, and agreement between these cut-off points. Methods: In this cross-sectional study (LASSYC study), 24-hour day respiratory symptoms were assessed by the Evaluating Respiratory Symptoms in COPD (E-RS) questionnaire, Nighttime Symptoms of COPD Instrument (NiSCI), Early Morning Symptoms of COPD Instrument (EMSCI), CAT and mMRC scores. Results: Among the 734 patients with COPD, 61% were male, age 69.6±8.7 years, FEV1% post-BD 49.1±17.5%, mMRC 1.8±1.0 and CAT 15.3±.8.1. By mMRC 33.7% were group-A, 29.2% group-B, 10.2% group-C and 26.9% group-D. By CAT 22.3% were group-A, 41% group-B, 4.8% group-C and 31.9% group-D. Using the mMRC the severity of E-RS, NiSCI and EMSCI scores increased from group A to D. Using the CAT, the groups B and D had the higher scores. Agreement between mMRC and CAT was 89.5% (Kappa statistics=75.7%). For mMRC score of 2, CAT score of =11 showed the maximum Youden's index (1.34). For mMRC score of 1, CAT score of =9 and =10 showed the maximum Youden's index (1.48). Conclusion: GOLD COPD classification by CAT seems to better discriminate 24-hour symptoms. Results do not support the equivalent use of CAT=10 and mMRC=2 for assessing symptoms.


2000 ◽  
Vol 92 (1) ◽  
pp. 6-6 ◽  
Author(s):  
Bruce Ben-David ◽  
Roman Frankel ◽  
Tatianna Arzumonov ◽  
Yuri Marchevsky ◽  
Gershon Volpin

Background Spinal anesthesia for surgical repair of hip fracture in the elderly is associated with a high incidence of hypotension. The synergism between intrathecal opioids and local anesthetics may make it possible to achieve reliable spinal anesthesia with minimal hypotension using a minidose of local anesthetic. Methods Twenty patients aged &gt; or = 70 yr undergoing surgical repair of hip fracture were randomized into two groups of 10 patients each. Group A received a spinal anesthetic of bupivacaine 4 mg plus fentanyl 20 microg, and group B received 10 mg bupivacaine. Hypotension was defined as a systolic pressure of &lt; 90 mmHg or a 25% decrease in mean arterial pressure from baseline. Hypotension was treated with intravenous ephedrine boluses 5-10 mg up to a maximum 50 mg, and thereafter by phenylephrine boluses of 100-200 microg. Results All patients had satisfactory anesthesia. One of 10 patients in group A required ephedrine, a single dose of 5 mg. Nine of 10 patients in group B required vasopressor support of blood pressure. Group B patients required an average of 35 mg ephedrine, and two patients required phenylephrine. The lowest recorded systolic, diastolic, and mean blood pressures as fractions of the baseline pressures were, respectively, 81%, 84%, and 85% versus 64%, 69%, and 64% for group A versus group B. Conclusions A "minidose" of 4 mg bupivacaine in combination with 20 microg fentanyl provides spinal anesthesia for surgical repair of hip fracture in the elderly. The minidose combination caused dramatically less hypotension than 10 mg bupivacaine and nearly eliminated the need for vasopressor support of blood pressure.


2014 ◽  
Vol 29 (1-2) ◽  
pp. 1-7
Author(s):  
Khadiza Begum ◽  
Rokeya Begum ◽  
Qazi Shamima Akhter ◽  
Nusrat Sultana ◽  
Shamima Bari

Background: There is an association between breast feeding & maternal lipid profile. Pregnancy related hyperlipidaemia reverse quickly with lactation. Objective: To observe Serum Total cholesterol & triglyceride in lactating & nonlactating mother. Method: The present cross sectional study was conducted in the Department of Physiology, Dhaka Medical College, Dhaka, during the period of July 2010 to June 2011. A total 300 subjects were included within the age limit from 20 to 40 years of women. Among them100 were normal healthy subjects & had child above 3 years were considered as group A (control). The rest 200 women were selected as study subject (group B) having child between the age 6 weeks to 2 years. Group B is again subdivided into group B1 (100 lactating mother) & group B2 (100 nonlactating mother). The subjects were selected from pediatric ward & OPD of pediatrics, DMCH and BSMMU, Dhaka. Data were collected in data collection sheet after taking informed written consent of the subjects. The study parameters total cholesterol & Triglyceride were done in the Department of Physiology, Dhaka Medical College. The data were analyzed by computer with SPSS programs using unpaired Student ?t’ test.Results: In group B1 total cholesterol & triglyceride levels were non significantly higher than that of group A but in group B2 these values were significantly higher than that of group A. Within the study groups all these values were significantly higher in nonlactating mother than lactating mother. It was observed that high level of study parameters were more in B2 than that of group B1. Conclusion: From the results of the present study it may be concluded that lactation has effect on lowering serum total cholesterol & triglyceride which may preferably related to health education for the mother. http://dx.doi.org/10.3329/bjpp.v29i1-2.20060Bangladesh J Physiol Pharmacol 2013; 29(1&2) : 1-7


2021 ◽  
pp. 39-40
Author(s):  
Avtar Singh Dhanju ◽  
Deepshikha Singla ◽  
Pashaura Singh ◽  
Ajay Chhabra ◽  
Sukhraj Kaur

Aim: The present study was undertaken with the aim to evaluate serum Gamma Glutamyl Transferase (GGT) levels in patients of acute coronary syndrome. Methodology: This cross-sectional study was conducted on 50 cases with acute coronary syndrome (Group A) and 50 healthy control subjects (Group B) meeting inclusion and exclusion criteria. Results: There is signicant rise in serum GGT levels in patients presenting with ACS in Group A as compared to Group B. Conclusion: Higher levels of GGT in ACS patients with risk factors such as hypertension, dyslipidemia and smoking may serve as biomarker to predict the occurrence of ACS.


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