scholarly journals PILL BURDEN, SLEEP QUALITY, ANXIETY, DEPRESSION IN PATIENTS WITH DIABETIC AND NON -DIABETIC CHRONIC KIDNEY DISEASE

Author(s):  
Shaik Khaja Shanawaz Basha

Background: Chronic kidney disease (CKD) has a significant impact upon the quality of life of patients due to multiple factors. One of major stress is due to medication effects which may affect in patients with chronic kidney disease quality of life. In patients with chronic kidney disease, anxiety disorders are often perceived to represent the symptoms of depression and sleep disturbances. Aim and objectives: Therefore the present study evaluated the role of Pill burden, sleep quality, anxiety and depression in patients with diabetic and Non -diabetic chronic kidney disease. Materials and methods: The present study was conducted in 198 pre dialysis CKD patients of 1 to 5 stages with and without Diabetes mellitus. Sleep quality was assessed by using Pittsburgh Sleep Quality Index (PSQI) which is a standard self- reported scale for assessment of sleep quality. Anxiety and depression scores were calculated by using Hospital Anxiety and Depression scale (HADS). Results: With increasing severity of disease burden, CKD patients were found to have more increase in pill burden, reduction in sleep quality, increase in anxiety and depression. This progression was found to be more significant in diabetic CKD patients when compared to non- diabetic CKD patients.  Conclusion: The present study findings conclude that patients with advanced stages of CKD experience a high symptom burden that impacts on their daily life. Diabetic CKD patients have been found to be more prone to altered sleep quality, anxiety and depression than non- diabetic CKD patients. Keywords: Chronic kidney disease, Diabetes mellitus, Pill burden, sleeps quality, anxiety and depression.

2018 ◽  
Vol 15 ◽  
pp. 42-49 ◽  
Author(s):  
Soraya Azmi ◽  
Adrian Goh ◽  
Noor Azimah Muhammad ◽  
Hizlinda Tohid ◽  
Mohd Radzniwan A. Rashid

2015 ◽  
Vol 18 ◽  
Author(s):  
Sonia Martínez-Sanchis ◽  
M. Consuelo Bernal ◽  
José V. Montagud ◽  
Anna Abad ◽  
Josep Crespo ◽  
...  

AbstractThis study evaluated health-related quality of life (HRQOL) in a Spanish sample of chronic kidney disease patients (n= 90) undergoing different renal replacement therapies, considering the influence of treatment stressors, mood, anxiety and quality of sleep. While all patients had worse physical functioning than controls (p< .01), only those undergoing haemodialysis (HD) showed worse physical well-being, occupational functioning, spiritual fulfillment and more health interference with work (p< .05). They also obtained higher depression scores than renal transplant patients (TX) (p= .005). Those TX receiving the immunosuppressor sirolimus exhibited more cardiac/renal, cognitive and physical limitations than the rest (p< .05). Dialysis vintage correlated positively with sleep disturbances and depression scores and negatively with total Quality of Life (QLI) (p< .05). HD patients experienced more psychological distress than peritoneal dialysis patients (PD) (p= .036). Regression models including sleep, anxiety and depression were estimated for subscales of HRQOL. In TX patients, low depressive scores related to an optimal QLI in almost all subscales, while in HD patients they explained part of the variability in psychological well-being, interpersonal functioning and personal fulfillment. HD condition results in a QLI more distant to the standards of controls.


2019 ◽  
Vol 36 (2) ◽  
Author(s):  
Ume Kalsoom

Objective: To investigate gender role in quality of life, anxiety, and depression in chronic kidney disease patients. The study hypothesized that men will score high on depression and, anxiety and will score low on quality of life and perceived social support as compare to women Methods: One hundred patients with chronic kidney diseases were selected using purposive sampling strategy from nephrology ward of Leady Reading Hospital, Peshawar. The participants were included both male (n=50) and female (n=50) ranging in age from 18-65 years (M=44.16, SD= 15.15) Patients were recruited on the basis of preset inclusion criteria i-e (willing to participat, could read, speak and understand urdu language, with no previous history of dialysis treatment) and exclusion criteria (Age > than 18, Previous psychiatric history, Diagnosis less than one year, Education less than high school). All participants completed Quality of Life Questionnaire, Anxiety and depression questionnaires. Results: Statistical analysis of independent sample t-test shows significant difference of men and women on QOL t(98)=2.34, p=0.021), anxiety t(98)=4.23, p=0.001), and depression t(98)=4.54, p=0.001) while no significant gender differences were reported on perceived social support t(98)= 0.98, p= 0.327. Conclusion: Male showed more depression, anxiety as compared to females while women reported poor quality of life as compared to men. doi: https://doi.org/10.12669/pjms.36.2.869 How to cite this:Um-e-Kalsoom. Gender role in anxiety, depression and quality of life in chronic kidney disease patients. Pak J Med Sci. 2020;36(2):---------. doi: https://doi.org/10.12669/pjms.36.2.869 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


2020 ◽  
Vol 22 (Supplement_2) ◽  
pp. ii181-ii181
Author(s):  
Pin-Yuan Chen ◽  
Hsiao-Yean Chiu ◽  
Pei-Ching Lin

Abstract BACKGROUND Sleep disturbances are common complaints in adult brain tumor patients and impact their quality of life profoundly. The prevalence and pattern of preoperative sleep disturbances are still unknown. MATERIAL AND METHOD There were 36 adult patients with primary brain tumors who were recruited before craniotomy. All participants completed a battery of questionnaires, including the Athens Insomnia Scale, Epworth Sleepiness Scale, Pittsburgh Sleep Quality Index, Brief Fatigue Inventory, Hospital Anxiety, and Depression Scale, Morningness-Eveningness Questionnaire, and EORTC-QLQ-BN20. Actigraphy was put on a non-dominant wrist for obtaining objective sleep parameters, such as the dichotomy index. RESULT The prevalence of preoperative insomnia, poor sleep quality, excessive daytimes sleepiness, and circadian disruption were all high but similar between benign and malignant brain tumor groups. Patients with glioma had poorer quality of life. Insomnia was the only sleep disturbance that significantly associated with quality of life in a multivariate linear regression modal. CONCLUSION Sleep disturbances are common in adult brain tumor patients. Insomnia worse the quality of life of these patients. A further longitudinal investigation of sleep disturbances and quality of life in brain tumor patients is worthful.


2016 ◽  
Vol 25 (3) ◽  
Author(s):  
Ana Carolina Ottaviani ◽  
Loren Carolina Betoni ◽  
Sofia Cristina Iost Pavarini ◽  
Karina Gramani Say ◽  
Marisa Silvana Zazzetta ◽  
...  

ABSTRACT To analyze the relationship between anxiety and depression and quality of life in chronic renal failure patients on hemodialysis. This is a correlational study with a cross-sectional, quantitative approach, conducted with 100 kidney patients under treatment at a Renal Replacement Therapy Unit in the state of São Paulo. Data were collected using a sociodemographic questionnaire, Hospital Anxiety and Depression Scale and Kidney Disease and Quality of Life Short-Form. A negative correlation was found between anxiety and depression and the quality of life domains. In addition, the average scores on the Kidney Disease and Quality of Life Short-Form were significantly lower in patients with anxiety and depressive symptoms. In conclusion, there is a negative correlation between depression and anxiety and the health-related quality of life of chronic renal failure patients on hemodialysis.


2020 ◽  
Vol 35 (Supplement_3) ◽  
Author(s):  
Fadwa Al-Ali ◽  
Rania Ibrahim ◽  
Mincy Mathew ◽  
Nadir Kheir ◽  
Ahmed Awaisu ◽  
...  

Abstract Background and Aims Diabetes mellitus (DM) is the leading cause of chronic kidney disease (CKD) and on of its top comorbidities. Its management places significant burden on patients and results in impairment of their health-related quality of life (HR-QOL). Little is known about diabetes mellitus treatment-related burden in patients with CKD. This study aimed to investigate the impact of diabetes mellitus on treatment-related burden and HR-QOL among CKD patients in Qatar. Method This was a mixed-method, sequential explanatory study conducted at Fahad Bin Jassim Kidney Center in Qatar on hemodialysis and pre-dialysis (GFR&lt;20 but not on dialysis yet) patients. Treatment-related burden and HR-QOL were assessed quantitatively using the Treatment Burden Questionnaire (TBQ) and the Kidney Disease Quality of Life (KDQOL™) questionnaire, respectively. To gain a deeper insight, qualitative one-to-one semi-structured interviews were conducted among the CKD patients. Quantitative data were analyzed descriptively and inferentially using SPSS version 24. Thematic content analysis was performed for the qualitative data. Results Two hundred-eighty CKD patients (hemodialysis = 223 and pre-dialysis (GFR &lt;20) = 57) were included. 157 has DM and 66 were non-DM (in hemodialysis) while 32 patients had DM vs 25 non-DM (in pre-dialysis). In general, 35% of patients reported moderate to high burden. Hemodialysis patients experienced significantly higher treatment burden compared to pre-dialysis patients with median (IQR) of 45 (36) versus 25 (33), respectively (p&lt;0.001). DM patients expressed significantly higher TBQ score compared to non-DM (47(40) vs. 36(27) p&lt;0.001). Retinopathy was associated with worsened treatment burden (TBQ 46.5(29) vs. 40(38) p=0.019). Medication burden and lifestyle change burden were the highest perceived treatment-related burden, followed by administrative, social, and financial burden. The presence of antidiabetic medications correlated with worse TBQ score (0.207 p&lt;0.001). There was a strong, negative correlation between TBQ score and KDQOL-36™ score [rs (251) = -0.616, p &lt;0.001]. Presence of DM was associated with worse KDQOL (2110(1055) vs. 2685(1170) p&lt;0.001). Thematic content analysis identified religion and faith in God as well as quality of the care provided as factors that reduce perceived treatment burden and improve patients’ HR-QOL. Conversely, medication burden, lifestyle changes, challenges with international travelling, financial burden, and empathy were factors that worsen perceived treatment-related burden and HR-RQOL. Conclusion This study suggests that diabetes mellitus and its treatment negatively impacts treatment-related burden and quality of life in CKD patients. This result should be considered in management strategies when designing healthcare interventions directed to CKD patients with diabetes mellitus.


2021 ◽  
Vol 2 (2) ◽  
pp. 038-041
Author(s):  
Pertiwi Perwiraningtyas ◽  
Ani Sutriningsih ◽  
Wahyu Dini Metrikayanto

Patients of chronic kidney disease require long-term hemodialysis therapy. However, this therapy has various complications, one of which is pruritus. Pruritus can interfere with individual activities, cause sleep disturbances, lesions and hyperpigmentation on the skin, to impact the patient's quality of life. So that non-pharmacological management is needed to treat pruritus. The design was cross sectional. The population in this community service was chronic kidney failure patients undergoing hemodialysis therapy in the hemodialysis room. The sample was patients who experience pruritus and undergo hemodialysis therapy at least 1x / week as many as 45 people. The variables were health education related to non-pharmacological management and pruritus. The instruments used leaflets and counseling program units for health education, while for pruritus used the Numeric Rating Scale. The average patient experienced pruritus on a scale of 5, which was a moderate category where itching was felt by frequent scratching. After health education, patients understand how to deal with pruritus with non-pharmacological methods so that the patient's quality of life becomes better.


2021 ◽  
Vol 2021 ◽  
pp. 1-7
Author(s):  
Jianfu Zhang ◽  
Shurong Shao ◽  
Chaohui Ye ◽  
Bengui Jiang

In this prospective study, we randomly divided 100 patients with perimenopausal syndrome equally into the control group (n = 50) receiving conventional treatment and the study group (n = 50) receiving estradiol valerate. The indicators observed were endometrial thickness, uterine volume, and the levels of LH (luteinizing hormone), FSH (follicle-stimulating hormone), and E2 (estradiol) of the patients before and after treatment. The Pittsburgh Sleep Quality Index (PSQI), Hamilton Anxiety/Depression Scale (HAMA/HAMD), Kupperman symptom score, and menopause-specific quality of life (MENQOL) were also applied to assess the sleep quality, negative emotions, severity of the condition, and quality of life of all patients, respectively. Our findings were that estradiol valerate is beneficial in improving serum sex hormone levels, sleep disturbances, negative mood, and quality of life in patients with perimenopausal syndrome and that its safety profile is high enough to warrant clinical promotion.


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