Prevalensi refluks laringofaring pada bayi laringomalasia primer

2012 ◽  
Vol 42 (2) ◽  
Author(s):  
Dina Putri Nasution ◽  
Susyana Tamin ◽  
Syahrial Hutauruk ◽  
Saptawati Bardosono

Background: Primary laryngomalacia is a congenital weakness of the supraglottis structures which collapsed during inspiration causing upper airway obstruction. This condition can cause changes in gradient of intrathoraxic-abdominal pressure resulting reflux of gastric juice into the upper airway causing laryngopharyngeal reflux (LPR). Purpose: To find out the prevalence of LPR as a comorbid disease of primary laryngomalacia in infant using fiberoptic laryngoscopy examination, to know the characteristics  of samples, and the correlation between laryngomalacia with LPR. Methods: This is a cross-sectional  study to assess the prevalence of LPR in infants with primary laryngomalacia at Cipto Mangunkusumo Hospital. LPR was diagnosed based on clinical signs from flexible laryngoscopy video records. Result: The prevalence of LPR was 90% in primary laryngomalacia. There were significant differences from three of five clinical findings with LPR, such as arytenoid edema/erythema (p<0,001), ventricular fold edema (p=0,001), and vocal fold edema (p<0,001). Conclusion: Most of the samples with laryngomalacia in this study also have LPR. The presence of LPR could worsen the clinical manifestation and delay the healing of laryngomalacia. Keywords: primary laryngomalacia, fiberoptic laryngoscopy, laryngopharyngeal reflux    Abstrak :  Latar belakang: Laringomalasia primer merupakan kelainan kongenital laring berupa kelemahan pada struktur supraglotis yang terhisap saat inspirasi dan menyebabkan sumbatan jalan napas atas. Kondisi ini dapat menyebabkan perubahan selisih tekanan intra-abdominal/ intratorakal sehingga terjadi refluks cairan lambung ke saluran napas atas, yang menyebabkan refluks laringofaring (RLF). Tujuan: Mengetahui prevalensi RLF pada bayi laringomalasia primer menggunakan pemeriksaan laringoskopi serat optik lentur, mengetahui karakteristik percontoh, dan hubungan laringomalasia primer dengan RLF.  Metode: Penelitian ini adalah penelitian observasional dengan metode potong lintang untuk mengetahui prevalensi RLF sebagai penyakit penyerta pada bayi laringomalasia di Rumah Sakit Cipto Mangunkusumo. Diagnosis RLF ditegakkan berdasarkan tanda klinis dari rekaman video laringoskopi serat optik lentur. Hasil: Prevalensi RLF diperoleh sebesar 90%. Terdapat tiga dari lima tanda klinis RLF yang berbeda bermakna dengan kejadian RLF, yaitu edema/eritema aritenoid (p<0,001), edema plika ventrikularis (p=0,001), dan edema plika vokalis (p<0,001). Kesimpulan: Hampir seluruh percontoh laringomalasia primer disertai dengan RLF. Penyakit penyerta RLF akan memperberat gejala dan memperpanjang waktu penyembuhan laringomalasia.   Kata kunci: laringomalasia primer, laringoskopi serat optik lentur, refluks laringofaring 

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Ameer Kakaje ◽  
Mohammad Marwan Alhalabi ◽  
Ayham Alyousbashi ◽  
Ayham Ghareeb

AbstractAllergic rhinitis (AR) is a common medical condition worldwide. It is an inflammation in the nasal mucosa due to allergen exposure throughout the year. Laryngopharyngeal reflux (LPR) is another medical condition that can overlap with AR. LPR can be considered an extra oesophageal manifestation of gastro-oesophageal reflux disease (GORD) or a different entity. Its diagnosis imposes a real challenge as it has a wide range of unspecific symptoms. Although AR and LPR are not life-threatening, they can severely affect the quality of life for years and cause substantial distress. Moreover, having AR is associated with having asthma which is also in turn associated with GORD. This is a cross-sectional study which used surveys distributed online on Social Media and targeted people across Syria. All participants who responded to the key questions were included. Reflux symptom index (RSI) was used for LPR, and score for allergic rhinitis (SFAR) was used for AR. Demographic questions and whether the participant had asthma were also included in the survey. We found that there was an association between the symptoms of LPR and AR p < 0.0001 (OR, 2.592; 95% CI 1.846–3.639), and their scores were significantly correlated (r = 0.334). Having asthma was associated with LPR symptoms p = 0.0002 (OR 3.096; 95% CI 1.665–5.759) and AR p < 0.0001 (OR 6.772; 95% CI 2.823–16.248). We concluded that there was a significant association between having LPR, AR, and asthma. We need more studies to distinguish between their common symptoms and aetiologies.


Author(s):  
Vishal Mehrotra ◽  
Gauri Mishra ◽  
Rohan Sachdev ◽  
Kriti Garg ◽  
Sekhar Mukherjee ◽  
...  

Background: In the present era, forensic odontology has expanded as one of the most remarkable and commendable branches of Forensic Sciences. Through forensic odontology, a dentist plays a very important role in crime investigation of any type. The main objective of the present study was to evaluate the knowledge, percipience and practical perception of forensic odontology among the dental practitioners in and around Kanpur city.Methods: A cross-sectional study was conducted from Jan-Mar 2019 among 207 dental practitioners in and around Kanpur city including 143 BDS and 64 MDS through a questionnaire proforma. The proforma consisted of 20 questions prepared on the topic of forensic Odontology and role of dentist in the field of forensic Odontology.Results: In this study, nearly 70% of dental practitioners were aware of the role of dentist in forensics, and around 60% of dental practitioners maintain dental records with recording of personal data and clinical findings being the most frequently used method. In the present study most of the dental practitioners were not aware of significance of chelioscopy (63%) and rugoscopy (66%) in field of forensic Odontology. Nearly 70% of dentist accepted the fact that their level of knowledge regarding forensic dentistry is inadequate and nearly 40% of them were not confident in giving any opinion regarding the same.Conclusions: This study shows that although there is an adequate awareness of role of dentist in forensic Odontology, but there is lack of good knowledge, confidence and practical approach of the dental practitioners towards forensic Odontology which may be due to lack of training, experience, exposure in field of forensics. Thus, the need of the hour lies in updating the knowledge and also developing interest of the dental practitioners regarding forensic Odontology.


2021 ◽  
Vol 8 ◽  
Author(s):  
Barbara Padalino ◽  
Francesco Cirone ◽  
Martina Zappaterra ◽  
Daniele Tullio ◽  
Gigliola Ficco ◽  
...  

Bovine respiratory disease (BRD) is a complex, multifactorial syndrome and one of the major welfare and economical concerns for the cattle industry. This 1-year cross-sectional study was aimed at documenting the prevalence of BRD-related pathogens and clinical signs before and after a long journey and at identifying possible predisposition factors. Male Limousine beef steers (n = 169) traveling from France to Italy were health checked and sampled with Deep Nasopharyngeal Swabs (DNS) at loading (T0) and 4 days after arrival (T1). Real-time quantitative PCR was used to quantify the presence of bovine viral diarrhea virus (BVDV), bovine respiratory syncytial virus (BRSV), bovine alphaherpesvirus 1 (BoHV-1), bovine coronavirus (BCoV), bovine adenovirus (BAdV), bovine parainfluenza virus 3 (BPIV-3), Histophilus somni, Mannheimia haemolytica, Mycoplasma bovis, and Pasteurella multocida. Weather conditions at departure and arrival were recorded, and the travel conditions were taken from the travel documentation. At T0, even if no animals displayed clinical signs, some of them were already positive for one or more pathogens. At T1, the number of animals displaying clinical signs and positive for BCoV, BAdV, BRSV, H. somni, M. haemolytica, M. bovis, and P. multocida increased dramatically (p &lt; 0.001). Transport also significantly increased co-infection passing from 16.0% at T0 to 82.8% at T1 (p &lt; 0.001). An extra stop during the journey seemed to favor BRSV, M. haemolytica, and P. multocida (p &lt; 0.05). Weather conditions, in particular sudden climate changes from departure to arrival and daily temperature variance, were found to be predisposing factors for many of the pathogens. The farm of arrival also played a role for BRSV, BAdV, and H. somni (p &lt; 0.05). BCoV increased dramatically, but no associations were found confirming that it spreads easily during transport phases. Our findings increased our understanding of factors increasing the likelihood of BRD-related pathogens shedding and can be useful to minimize the incidence of BRD and to implement animal transport regulations.


2019 ◽  
Vol 2 ◽  
pp. 28-28
Author(s):  
Al-Rahim Habib ◽  
Raewyn Campbell ◽  
Larry Kalish ◽  
Eugene H. Wong ◽  
Jessica Grayson ◽  
...  

Author(s):  
Mehran Hesaraki

Background: This article aimed to assessment clinical signs and symptoms, paraclinical tests and histopathological results in children with acute appendicitis.Methods: A cross-sectional study conducted on 100 children with acute appendicitis in an urban hospital in southeast of Iran from January to December 2016. Participants were selected by simple random sampling method. Clinical signs and symptoms, paraclinical tests and histopathological results recorded in checklists. The data were analyzed using SPSS 22.Results: Mean age of the patients was 10.26±3.25, fourthly-eight of patients (58.5%) were males and 34 patients (41.5%) were females. The most frequent clinical signs and symptoms were acute suppurative appendicitis with peri appendicitis (45.83%) and acute suppurative appendicitis (39.58%). The most frequent results in ultrasound reports were Intestinal loop thickness greater than 6 mm without peristalsis (positive report) (46.34%) and Invisible appendix (nega Hesaraki tive report) (13.41%).Conclusions: The results of this study showed that abdominal pain and RLQ tenderness were the most common signs and symptoms and WBC left-shift was the most common laboratory finding. Since the rate of negative appendectomy in this study was consistent with surgical results and other articles, it is concluded that diagnostic accuracy of preoperative appendectomy was acceptable and most children with acute appendicitis underwent appendectomy.


2020 ◽  
Vol 7 ◽  
Author(s):  
Tasneem Imam ◽  
Justine S. Gibson ◽  
Mohammad Foysal ◽  
Shetu Bhusan Das ◽  
Suman Das Gupta ◽  
...  

Commercial poultry production is growing rapidly in Bangladesh to address the increasing demand for poultry meat and eggs. Challenges faced by producers include the occurrence of poultry diseases, which are usually treated or controlled by antimicrobials. A cross-sectional study was conducted on 57 commercial layer and 83 broiler farms in eight subdistricts of the Chattogram district, Bangladesh, to assess antimicrobial usage in relation to clinical signs observed in chicken flocks on these farms. Of the 140 commercial chicken farms, 137 (97.9%) used antimicrobials and 24 different antimicrobial agents were administered. On layer farms, the most commonly used antimicrobials were ciprofloxacin (37.0% of farms, 20/54), amoxicillin (33.3%, 18/54), and tiamulin (31.5%, 17/54), while on broiler farms, colistin (56.6%, 47/83), doxycycline (50.6%, 42/83), and neomycin (38.6%, 32/83) were most commonly administered. Only 15.3% (21/137) of farmers used antimicrobials exclusively for therapeutic purposes, while 84.7% (116/137) of farmers used them prophylactically, administering them either for prophylactic purposes only (22.6% of farmers, 31/137) or in combination with therapeutic purposes (62.1% of farmers, 85/137). About 83.3% (45/54) of layer farmers were selling eggs while antimicrobials were being administered compared to 36.1% (30/83) of the broiler farmers selling broiler chickens while administering antimicrobials. Overall, 75.2% (103/137) of farmers reported clinical signs for which they administered antimicrobials, while 24.8% (34/137) of farmers reported no clinical signs but still administered antimicrobials. Respiratory signs (71.8% of farms with clinical signs, 74/103) were most commonly reported, followed by enteric signs (32.0%, 33/103) and increased mortality (16.5%, 17/103). About 37.2% (51/137) of farmers bought antimicrobials exclusively from feed and chick traders, followed by veterinary medical stores (35.0%, 48/137). Purchasing antimicrobials from feed and chick traders was more common among broiler than layer farmers. It is recommended that commercial poultry farmers should keep records of antimicrobials used with dosage and duration of administration along with indication of use. This would allow farmers and veterinarians to review if antimicrobial usage had the desired effects and to evaluate the appropriate use of antimicrobial agents under an antimicrobial stewardship approach.


2017 ◽  
Vol 16 (1) ◽  
Author(s):  
Mohd Hafidz Ithnin ◽  
Azrin Esmady Ariffin ◽  
Khairidzan Mohd Kama

Introduction: The clinical evaluation of the three layers of tear film is still poorly described. The purpose of this study is to evaluate the value of aqueous assessment in diagnosing dry eye. Materials and method: Schirmer test with anaesthesia (STA) and tear meniscus height (TMH) measurement were conducted on non-dry eye (NDE) and dry eye (DE) subjects in this cross-sectional study. The NDE and DE subjects were classified using two types of classification; classification 1 and classification 2. Results: 321 subjects with 642 eyes were recruited in the study. STA was significantly correlated with TMH (r = 0.24, p < 0.001) in all 642 eyes. The comparison between nondry and dry eye subjects in STA and TMH were not significantly different (p > 0.05) if the Classification 1 was used to define dry eye. In Classification 2, there were significantly different between NDE (12.5 ± 8.2 mm) and DE (3.4 ± 0.8 mm) subjects in STA (p < 0.001). Similar trend was also depicted in TMH based on the definition of dry eye stated in Classification 2 (NDE = 0.45 ± 0.20 mm, DE = 0.39 ± 0.14 mm; p < 0.05). Conclusion: The value of STA and TMH were lower significantly in dry eye subjects. However, the significant outcomes were only demonstrated if the clinical signs of dryness were used in the definition of dry eye.


2014 ◽  
Vol 2014 ◽  
pp. 1-8 ◽  
Author(s):  
Aija-Maaria Hietala-Lenkkeri ◽  
Mimmi Tolvanen ◽  
Pentti Alanen ◽  
Kaisu Pienihäkkinen

Aim. To reveal the additional value of radiographic bitewings (BW) in detection of caries and in comparing the occurrence of clinically undetected severe decay between 14-year olds with and without clinically observed dentinal caries in a low-caries prevalence population.Design. The cross-sectional study used 363 pairs of radiographs read by one examiner without knowledge of the clinical findings. The yield was analyzed on a tooth surface level by cross tabulating the clinical and radiographic information and on an individual level by counting the number of yield surfaces for all subjects. Mann-WhitneyUtest was used.Results. On a tooth surface level, the contribution of BW was the greatest on the occlusal surfaces of the first molars, where established or severe dentinal decay was registered in BW in 11% of clinically sound surfaces and in 40% of established cavitated enamel lesions. On an individual level, 53% of subjects benefited from BW. The subjects clinically DMFS > 0 benefited more than the clinically DMFS = 0 subjects (P=.004), nearly 60% in relation to 47%, respectively.Conclusions. In a low-caries prevalence population a remarkable portion of both clinically DMFS = 0 and DMFS > 0 14-year olds benefit from BW examination. Most of the benefit is obtained on the occlusal surfaces of the first and the second permanent molars.


2018 ◽  
Vol 48 (4) ◽  
pp. 313-316 ◽  
Author(s):  
Tchin Darre ◽  
Bathokédeou Amana ◽  
Essobozou Pegbessou ◽  
Foma Winga ◽  
Dolou Warou ◽  
...  

Tuberculosis (TB) remains a real public health concern in Africa; thyroid localisation of the disease is a very rare form of extrapulmonary TB. We conducted a descriptive and cross-sectional study on all histologically proved cases of thyroid TB diagnosed in Togo over the last 20 years. Eleven cases of TB of the thyroid were identified, of which nine were in women, with an average age of 29.4 ± 0.2 years. The clinical signs were the presence of a nodule in seven, an abscess in three and a swelling with cutaneous fistulisation in one. Thyroid involvement alone was found in four, associated with pleuropulmonary TB in six and mammary TB in one. Human immunodeficiency virus (HIV) co-infection was present in six. All histopathology results showed inflammatory granulomata with caseous necrosis. The clinical features are often misleading and pose a real diagnostic problem, especially with differentials of simple abscess and cancer.


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