scholarly journals Pengaruh Prone positioning Terhadap Respiratory Rate dan Saturasi Oksigen Pada Bayi Gawat Napas (Respiratory Distress Syndrome ) di Ruang NICU RSUD Gunung Jati Cirebon

2021 ◽  
Vol 3 (4) ◽  
pp. 500-506
Author(s):  
Titin Supriatin ◽  
Yani Nurhayani
Keyword(s):  
Respiratory Distress Syndrome ◽  
Respiratory Distress ◽  
Oxygen Saturation ◽  
Respiratory Rate ◽  
Heat Loss ◽  
Distress Syndrome ◽  
Control Group ◽  
Prone Positioning ◽  
Post Test ◽  
Equivalent Control

ABSTRACT: THE EFFECT OF PRONE POSITIONING ON RESPIRATORY RATE AND OXYGEN SATURATION IN INFANTS WITH RESPIRATORY DISTRESS SYNDROME IN NEONATUS INTENSIVE CARE UNIT AT GUNUNG JATI HOSPITAL CIREBON. Background: Respiratory Distress Syndrome (RDS), also known as respiratory distress syndrome, is a major threat to infants and children who are recovering from a serious illness. Currently, RDS is the leading cause of newborn death. Management of RDS includes improving oxygenation, prevention of infection, maintaining vascular pressure and cardiac output, adequate nutrition, positioning to improve functional residual capacity. The prone positioning for the baby is an energy-saving position because this position will reduce heat loss. This is because, in the prone positioning, the baby's feet are flexed, thereby reducing the body's metabolism resulting in a decrease in the amount of heat loss. Another reason is that in the prone position the baby's face touches the blanket or bed so that the baby's face is not exposed to air and allows a decrease in heat loss through the radiation process.Purpose: The purpose of this study was to determine the effect of the prone positioning on respiratory rate and oxygen saturation in respiratory distress syndrome (RDS) infants in NICU at Gunung Jati Hospital, Cirebon.Methode: The method of this research is a quasi-experimental study with a non-equivalent control group pre and post-test design. This study used a random sampling technique for 38 respondents. The analysis in this study uses paired t-test analysis.Result: The results showed that prone positioning can support the improvement of respiratory rate and oxygen saturation in infants with RDS.Conclusion: There are improvements in respiratory rate and oxygen saturation after prone positioning has been given.  Keywords: Prone, Respiratory distress syndrome, Respiratory rate, oxygen saturation. INTISARI : PENGARUH PRONE POSITIONING TERHADAP RESPIRATORY RATE DAN SATURASI OKSIGEN PADA BAYI GAWAT NAPAS (RESPIRATORY DISTRESS SYNDROME ) DI RUANG NICU RSUD GUNUNG JATI CIREBON Latar belakang : Respiratory Distress syndrome (RDS) atau dikenal dengan sindrom gawat napas, merupakan ancaman utama pada bayi dan anak yang berada pada masa pemulihan dari penyakit berat. Saat ini RDS merupakan penyebab utama kematian bayi baru lahir. Penatalaksanaan RDS diantaranya adalah memperbaiki oksigenasi, pencegahan infeksi, mempertahankan tekanan vascular dan curah jantung, nutrisi yang adekuat, pemberian posisi untuk memperbaiki kapasitas residu fungsional. Posisi prone pada bayi merupakan posisi yang sangat menghemat energi, karena posisi ini akan menurunkan kehilangan panas. Hal ini disebabkan karena pada posisi prone, kaki bayi fleksi sehingga menurunkan metabolisme tubuh akibatnya terjadi penurunan jumlah kehilangan panas. Penyebab lain juga dikarenakan pada posisi prone wajah bayi menyentuh selimut atau tempat tidur sehingga wajah bayi tidak terpapar dengan udara dan memungkinkan terjadinya penurunan kehilangan panas melalui proses radiasiTujuan : penelitian ini adalah untuk megetahui pengaruh posisi prone terhadap respiratory rate dan saturasi oksigen pada bayi respiratory distress syndrome (RDS) di ruang NICU RSUD Gunung Jati Cirebon.Metode Penulisan : Penelitian ini merupakan penelitian kuasi experimental dengan desain pre and post test non equivalent control group. Penelitian ini menggunakan tehnik random sampling terhadap 38 responden. Analisis dalam penelitian ini menggunakan analisis paired t test.Hasil : Hasil penelitian menunjukkan bahwa posisi prone dapat mendukung perbaikan respiratory rate dan saturasi oksigen pada bayi dengan RDS.Kesimpulan : terdapat peningkatan respiratory rate dan saturasi oksigen setelah dilakukan intervensi posisi prone. Kata kunci: Prone, Respiratory distress syndrome, Respiratory rate, saturasi oksigen.

scholarly journals Clinical efficacy of combinations of nebulised fluticasone, salbutamol and furosemide on lung function in premature calves with respiratory distress syndrome

2017 ◽  
Vol 62 (No. 10) ◽  
pp. 541-552 ◽  
Author(s):  
R. Yildiz ◽  
M. Ok
Keyword(s):  
Carbon Dioxide ◽  
Respiratory Distress Syndrome ◽  
Respiratory Distress ◽  
Oxygen Saturation ◽  
Distress Syndrome ◽  
Blood Gas Analysis ◽  
Gas Analysis ◽  
Control Group ◽  
Peripheral Oxygen Saturation ◽  
Arterial Blood

Surfactant deficiency, poor development of the lung structure and fibrosis as a result of inflammation are thought to play an important role in the development of respiratory distress syndrome in premature calves. Nebulised steroid (fluticasone), bronchodilator (salbutamol) and diuretics (furosemide) can be used in combination alongside standard treatment procedures for premature calves, and might improve viability as observed in infants, foals and horses with pulmonary disorders. Twenty-five premature calves with respiratory distress syndrome were used in this study. Oxygen and supportive treatment were administered to all groups. The first group was used as a control group (Group 1). The nebulised drug combinations were as follows: Group 2: fluticasone + salbutamol, Group 3: salbutamol + furosemide, Group 4: fluticasone + furosemide and Group 5: fluticasone + salbutamol + furosemide. During the 72-h time period of the study, fluticasone (15 µg/kg/12 h), salbutamol (0.025 mg/kg/6 h) and furosemide (1 mg/kg/12h) were applied for 5 min. Arterial blood samples were collected from the auricular artery at 0 h and at 1, 24, 48 and 72 h for blood gas analysis. Significant (P < 0.05) increases in arterial partial oxygen, oxygen saturation and peripheral oxygen saturation and decreases in arterial partial carbon dioxide, lactate and respiration rate were observed in all the nebulised treatment groups, while a statistical difference was observed only for arterial partial carbon dioxide in control group. When comparing the treated groups with the control, it may be concluded that nebulised drugs are highly effective in the therapy of premature calves with respiratory distress syndrome, while the different nebulised groups exhibited similar efficacies.

scholarly journals Infection related catheter complications in patients undergoing prone positioning for acute respiratory distress syndrome: an exposed/unexposed study

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Guillaume Louis ◽  
Thibaut Belveyre ◽  
Audrey Jacquot ◽  
Hélène Hochard ◽  
Nejla Aissa ◽  
...  
Keyword(s):  
Acute Respiratory Distress Syndrome ◽  
Respiratory Distress Syndrome ◽  
Respiratory Distress ◽  
Distress Syndrome ◽  
Standard Of Care ◽  
Infectious Complications ◽  
Exposed Group ◽  
Control Group ◽  
Prone Positioning ◽  
Catheter Complications

Abstract Background Prone positioning (PP) is a standard of care for patients with moderate–severe acute respiratory distress syndrome (ARDS). While adverse events associated with PP are well-documented in the literature, research examining the effect of PP on the risk of infectious complications of intravascular catheters is lacking. Method All consecutive ARDS patients treated with PP were recruited retrospectively over a two-year period and formed the exposed group. Intensive care unit (ICU) patients during the same period without ARDS for whom PP was not conducted but who had an equivalent disease severity were matched 1:1 to the exposed group based on age, sex, centre, length of ICU stay and SAPS II (unexposed group). Infection-related catheter complications were defined by a composite criterion, including catheter tip colonization or intravascular catheter-related infection. Results A total of 101 exposed patients were included in the study. Most had direct ARDS (pneumonia). The median [Q1–Q3] PP session number was 2 [1–4]. These patients were matched with 101 unexposed patients. The mortality rates of the exposed and unexposed groups were 31 and 30%, respectively. The incidence of the composite criterion was 14.2/1000 in the exposed group compared with 8.2/1000 days in the control group (p = 0.09). Multivariate analysis identified PP as a factor related to catheter colonization or infection (p = 0.04). Conclusion Our data suggest that PP is associated with a higher risk of CVC infectious complications.

The Effect of Quarter Turn from Prone on Oxygen Saturation among Premature Babies with Respiratory Distress Syndrome

2018 ◽  
Vol 13 (1) ◽  
pp. 38
Author(s):  
Puji Lestari ◽  
Dian Susmarini ◽  
Sidik Awaludin
Keyword(s):  
Respiratory Distress Syndrome ◽  
Respiratory Distress ◽  
Oxygen Saturation ◽  
Prone Position ◽  
Distress Syndrome ◽  
Sampling Technique ◽  
Wilcoxon Test ◽  
Premature Babies ◽  
Before And After ◽  
Post Test

<p>The rate of death and illnesses on premature babies is mostly respiratory distress syndrome (RDS). Desaturated-period frequently occurs on premature babies with RDS. One intervention to prevent it is a quarter turn from prone position. The research design was pre-experimental study with one group pre- and post-test design. This study involved 20 respondents that were selected with consecutive sampling technique. The setting of the research was in Perinatology ward at Prof. Dr. Margono Soekarjo. The oxygen saturation was examined before and after 2 hours of intervention. Data was then analyzed with Wilcoxon test. The results showed that median value of SpO2 before quarter turn from prone position was 94%, and its value after two hours of intervention was 96.5%. It was found that there was a significant effect in giving quarter turn from prone position to oxygen saturation on premature babies with RDS. Quarter turn from prone position was able to increase oxygen saturation on premature babies with RDS and is possible to be implemented in perinatology room.</p>

scholarly journals Inhalationally Administered Semifluorinated Alkanes (SFAs) as Drug Carriers in an Experimental Model of Acute Respiratory Distress Syndrome

Pharmaceutics ◽  
2021 ◽  
Vol 13 (3) ◽  
pp. 431
Author(s):  
Matthias Otto ◽  
Jörg Krebs ◽  
Peter Welker ◽  
René Holm ◽  
Manfred Thiel ◽  
...  
Keyword(s):  
Acute Respiratory Distress Syndrome ◽  
Respiratory Distress Syndrome ◽  
Respiratory Distress ◽  
Distress Syndrome ◽  
Lung Mechanics ◽  
Systemic Absorption ◽  
Control Group ◽  
Pharmacokinetic Data ◽  
Tnf Α ◽  
Semifluorinated Alkanes

Aerosol therapy in patients suffering from acute respiratory distress syndrome (ARDS) has so far failed in improving patients’ outcomes. This might be because dependent lung areas cannot be reached by conventional aerosols. Due to their physicochemical properties, semifluorinated alkanes (SFAs) could address this problem. After induction of ARDS, 26 pigs were randomized into three groups: (1) control (Sham), (2) perfluorohexyloctane (F6H8), and (3) F6H8-ibuprofen. Using a nebulization catheter, (2) received 1 mL/kg F6H8 while (3) received 1 mL/kg F6H8 with 6 mg/mL ibuprofen. Ibuprofen plasma and lung tissue concentration, bronchoalveolar lavage (BAL) fluid concentration of TNF-α, IL-8, and IL-6, and lung mechanics were measured. The ibuprofen concentration was equally distributed to the dependent parts of the right lungs. Pharmacokinetic data demonstrated systemic absorption of ibuprofen proofing a transport across the alveolo-capillary membrane. A significantly lower TNF-α concentration was observed in (2) and (3) when compared to the control group (1). There were no significant differences in IL-8 and IL-6 concentrations and lung mechanics. F6H8 aerosol seemed to be a suitable carrier for pulmonary drug delivery to dependent ARDS lung regions without having negative effects on lung mechanics.

BODY WATER COMPARTMENTS IN THE PREMATURE INFANT, WITH SPECIAL REFERENCE TO THE EFFECTS OF THE RESPIRATORY DISTRESS SYNDROME AND OF MATERNAL DIABETES AND TOXEMIA

PEDIATRICS ◽  
1962 ◽  
Vol 29 (6) ◽  
pp. 883-889
Author(s):  
Wesley M. Clapp ◽  
L. Joseph Butterfield ◽  
Donough O'Brien
Keyword(s):  
Respiratory Distress Syndrome ◽  
Respiratory Distress ◽  
Total Body Water ◽  
Distress Syndrome ◽  
Body Water ◽  
Control Group ◽  
Extracellular Water ◽  
Water Compartments ◽  
Significant Difference ◽  
Total Body

Normal values for both total body water and extracellular water have been determined in 86 premature infants aged 1 to 90 days and weighing 940 to 2,435 gm, with use of the techniques of deuterium oxide and bromide dilution. Nine full-term infants aged 1 to 6 days and weighing 2,590 to 4,985 gm were similarly studied. Nine infants with the respiratory distress syndrome and eight infants of toxemic mothers studied in the first 24 hours of life showed no significant difference in their body water compartments in comparison to a control group of normal infants matched for age and weight. Seven infants of diabetic mothers studied in the first 24 hours of life showed a significant decrease in total body water, expressed as percentage of body weight, with a normal intracellular to extracellular water ratio. These data indirectly support other evidence that there is an increase in body fat in these infants at birth. See Table in the PDF file

Corticosteroids as Primary Therapeutic Agents in Respiratory Distress Syndrome (RDS)

PEDIATRICS ◽  
1973 ◽  
Vol 51 (5) ◽  
pp. 952-954
Author(s):  
Philip M. Farrell ◽  
Richard D. Zachman
Keyword(s):  
Respiratory Distress Syndrome ◽  
Respiratory Distress ◽  
Distress Syndrome ◽  
Therapeutic Agents ◽  
Control Group ◽  
Prophylactic Therapy ◽  
Supportive Management ◽  
First Time

The long awaited article by Liggins and Howie1 was received with great enthusiasm. Although one must remain cautiously optimistic, it would appear that for the first time an agent is available which transcends the previous methods of supportive management and provides at least a primary approach to prophylactic therapy for RDS. Their data for steroid-treated infants of 26 to 32 weeks' gestation are impressive statistically and the incidence of RDS in the control group (69.6%) is a credible figure based on current estimates.2

An Evidence-Based Protocol for Manual Prone Positioning of Patients With ARDS

2021 ◽  
Vol 41 (6) ◽  
pp. 55-60
Author(s):  
Patrick Ryan ◽  
Cynthia Fine ◽  
Christine DeForge
Keyword(s):  
Mechanical Ventilation ◽  
Acute Respiratory Distress Syndrome ◽  
Respiratory Distress Syndrome ◽  
Respiratory Distress ◽  
Distress Syndrome ◽  
Medical Center ◽  
Academic Medical Center ◽  
Prone Positioning ◽  
Hypoxemic Respiratory Failure ◽  
Unplanned Extubations

Background Manual prone positioning has been shown to reduce mortality among patients with moderate to severe acute respiratory distress syndrome, but it is associated with a high incidence of pressure injuries and unplanned extubations. This study investigated the feasibility of safely implementing a manual prone positioning protocol that uses a dedicated device. Review of Evidence A search of CINAHL and Medline identified multiple randomized controlled trials and meta-analyses that demonstrated both the reduction of mortality when prone positioning is used for more than 12 hours per day in patients with acute respiratory distress syndrome and the most common complications of this treatment. Implementation An existing safe patient-handling device was modified to enable staff to safely perform manual prone positioning with few complications for patients receiving mechanical ventilation. All staff received training on the protocol and use of the device before implementation. Evaluation This study included 36 consecutive patients who were admitted to the medical intensive care unit at a large academic medical center because of hypoxemic respiratory failure/acute respiratory distress syndrome and received mechanical ventilation and prone positioning. Data were collected on clinical presentation, interventions, and complications. Sustainability Using the robust protocol and the low-cost device, staff can safely perform a low-volume, high-risk maneuver. This method provides cost savings compared with other prone positioning methods. Conclusions Implementing a prone positioning protocol with a dedicated device is feasible, with fewer complications and lower costs than anticipated.

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