THE RISK OF DEVELOPING NON-CARCINOGENIC EFFECTS IN CHILDREN IN INDUSTRIAL CITY IN MULTICOMPARTMENT CONTAMINATION WITH CHEMICAL POLLUTANTS

Introduction. Environmental factors can cause a gain in prevalence of a significant number of diseases in the population. The effect of various components on the body of children and adolescents becomes especially relevant on the territory of an industrial city, due to its increased sensitivity to adverse effects in connection with the ongoing processes of both growth and development. The article presents the results of an assessment of the non-carcinogenic risk to the health of the children living in the industrial city of Orenburg. Material and methods. The results of laboratory studies of atmospheric air, water from centralized sources of water supply and food products as sources of potential health risks for children living in the city of Orenburg were evaluated. Hygienic and statistical research methods were used. Results. In the industrial city, the priority media that form a high risk of developing non-carcinogenic effects were found to be contaminated food and drinking water, which create a high and very high non-carcinogenic risk for hormonal (up to HI = 13.8), cardiovascular (up to HI = 18.3), central nervous systems (up to HI = 8.3) in children and adolescents and effects on the blood (up to HI = 19.0) and kidneys (up to HI = 8.8), as well as atmospheric air when exposed to the respiratory system (HI = 7.2), which may be one of the reasons for the deviation in their state of health at the population level. Conclusion. The complex multicomponent impact of risk factors on children living in an industrial city is a well-studied problem, the relevance of which does not decrease. Modern concepts of risk assessment make it possible to identify priority environments and their contaminants, which, of course, makes management decisions more focused both at the population and individual levels. The priority media were established to be contaminated with drinking water and contaminated food products, which form a high non-carcinogenic risk for the hormonal, cardiovascular, central nervous systems of children and adolescents and the effect on blood in the long-term dynamics, which may be one of the causes of deviations in their state health at the population level.

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The risk of developing non-carcinogenic effects in children in industrial city in multicompartment contamination with chemical pollutants

Hygiene and Sanitation ◽

10.47470/0016-9900-2020-99-3-242-245 ◽

2020 ◽

Vol 99 (3) ◽

pp. 242-245

Author(s):

Андрей Геннадьевич Сетко ◽

Ж.К. K. Мрясова ◽

Е.А. A. Терехова ◽

А.В. V. Тюрин

Keyword(s):

Drinking Water ◽

Children And Adolescents ◽

Population Level ◽

Food Products ◽

Carcinogenic Risk ◽

Atmospheric Air ◽

Industrial City ◽

Contaminated Food ◽

Central Nervous Systems ◽

Carcinogenic Effects

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Risk to Kaluga Population Health when Exposed to Air Pollutants

Safety in Technosphere ◽

10.12737/article_5d8b1e1688ea46.18681010 ◽

2019 ◽

Vol 7 (5) ◽

pp. 28-34

Author(s):

В. Иванова ◽

V. Ivanova ◽

Г. Лаврентьева ◽

G. Lavrenteva ◽

Р. Шошина ◽

...

Keyword(s):

Air Pollution ◽

Nitrogen Dioxide ◽

Population Health ◽

Air Pollutants ◽

Suspended Solids ◽

Hazard Index ◽

Carcinogenic Risk ◽

Territorial Expansion ◽

Atmospheric Air ◽

Carcinogenic Effects

Assessment of risk to Kaluga population health has been carried out taking into account both air pollution with nitrogen dioxide, carbon monoxide and suspended solids (dust), and danger coefficients related to development of non-carcinogenic effects for specific substances, and the hazard index for a group of substances with unidirectional impact. An alarming risk prevailed for the population health in the period from 2013 to 2016. The main contribution in this risk formation was made by atmospheric air pollution with nitrogen dioxide and suspended solids. The tendency for territorial expansion of city’s controlled areas with a predominance of acceptable non-carcinogenic risk to public health in 2017 has been established.

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Assessment of environmental risks from atmospheric air pollution in industrially developed regions of Ukraine

Journal of Geology Geography and Geoecology ◽

10.15421/111947 ◽

2019 ◽

Vol 28 (3) ◽

pp. 511-518 ◽

Cited By ~ 1

Author(s):

A. N. Nekos ◽

Yu. V. Medvedeva ◽

N. I. Cherkashyna

Keyword(s):

Air Pollution ◽

National Level ◽

Ambient Air ◽

Carcinogenic Risk ◽

Environmental Risks ◽

Acceptable Level ◽

Monitoring And Control ◽

Atmospheric Air ◽

Carcinogenic Effects ◽

Level Of Risk

Currently, atmospheric pollution is one of the main causes of premature mortality in the world. The problem is especially relevant for economically underdeveloped countries, in particular Ukraine, the economy of which has been developing for a long time in an extensive way. The complicated socio-ecological situation in the territory of the country is due, first of all, to insufficient financing of the medical industry and environmental protection, outdated technologies in industries, etc. The purpose of the study is to assess the environmental risks of atmospheric air pollution in industrialized regions of Ukraine. Kharkiv and Dnipro regions, which are part of the Donetsk-Prydnistrovsky economic macro-district, a powerful center of metallurgy and machine-building of the national level, were selected for the study. As part of the study, the ambient air condition was assessed from the point of view of sanitary-hygienic norms in compliance with state environmental standards as well as the risks of carcinogenic and non-carcinogenic effects from atmospheric pollution.Regional monitoring data on average annual concentrations of common pollutants and heavy metals in the atmospheric air of the cities of Kharkiv and Dnipro regions were used in calculations, averaged over the period from 2014 to 2016. The results of calculations have shown that the total non-carcinogenic risk from atmospheric air pollution in all studied cities exceeds the permissible level: Dnipro – 19.8 HQ; Kamianske– 23.3 HQ; Kryviy Rig – 19.3 HQ; Kharkiv – 11.9 HQ. The pollutants: PM2.5, copper, formaldehyde, nitrogen dioxide, manganese and phenol mostly contribute to the greatest non-carcinogenic risk. The dominance of these chemicals and elements in the structure of pollution in the studied cities leads to high probability of development of harmful effects in the respiratory organs – 11.1 to 22.3 HQ; cardiovascular system – 2.9 to 12.3 HQ; immune system – 1.7 to 4.7 HQ; eyes – 0.8 to 4 HQ; central nervous system – 1,4 to 4,6 HQ. The risk of carcinogenic effects is calculated for substances with proven carcinogenic effects: formaldehyde, nickel, cadmium, lead and chromium. The obtained carcinogenic risk from atmospheric air pollution within the studied cities falls into two categories: conventionally acceptable level of risk and acceptable level of risk. The greatest carcinogenic danger is from pollution of atmospheric air by chromium. Contribution of chromium to total carcinogenic risk ranges from 53.6 to 90.6%. Taking into account the obtained results, it is expedient to include the assessment of the risks to the population’s health in the system of monitoring and control of the environment in Ukraine.

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Assessment of carcinogenic risk caused by the impact of the environmental factors on urban population health

Hygiene and Sanitation ◽

10.47470/0016-9900-2021-100-3-188-195 ◽

2021 ◽

Vol 100 (3) ◽

pp. 188-195

Author(s):

Valery N. Rakitskii ◽

Yuriy I. Stepkin ◽

Oleg V. Klepikov ◽

Semyon A. Kurolap

Keyword(s):

Public Health ◽

Drinking Water ◽

Ambient Air ◽

Carcinogenic Risk ◽

Quantitative Risk Assessment ◽

Pollutant Emissions ◽

Atmospheric Air ◽

Laboratory Control ◽

Environmental Objects ◽

The Impact

Introduction. The high level of environmental pollution in industrial cities, including carcinogens, causes an unacceptable risk to public health. In this regard, a quantitative risk assessment is required to develop preventive measures to reduce it. The aim of the study was to assess the carcinogenic risk to the health of the population of an industrialized city, caused by the probable presence of carcinogens in the ambient air, drinking water of the centralized water supply system, and the soil of the residential area. Material and research methods. The laboratory control of the content of carcinogens in environmental objects of the city of Voronezh for 2017-2020 was used as the reference data. The carcinogenic risk was assessed under the provisions of Guideline R. 2.1.10.1920-04 “Guidelines for assessing the risk to public health when exposed to chemicals that pollute the environment.” Results. Taking into account the regional peculiarities of the composition of pollutant emissions into the atmospheric air, 1,3-butadiene (source - production of synthetic rubber) should be classified as priority carcinogens requiring systematic monitoring and measures to reduce emissions and, accordingly, concentrations in the surface layer of atmospheric air and chromium6+ compounds (the main source is an aircraft plant), which contribute 69.9-75.7% and 21.7-26.9%, respectively, to the total values of the individual carcinogenic risk, which exceeds the maximum permissible level (1 • 10-4). The carcinogenic risk from exposure to drinking water pollutants (halogenated organic substances) and soil (under the scenario of accidental ingestion by preschool children) is below the maximum permissible risk (1 • 10-4). Conclusion. It is necessary to pay attention to increasing the sensitivity of the applied laboratory control methods, expanding the list of controlled carcinogenic pollutants, improving the monitoring system of carcinogens, and implementing measures to reduce the carcinogenic risk associated with atmospheric air pollution.

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MODERN APPROACHES OF ESTIMATION OF RISK FACTORS INTERMITTENT INFLUENCE

GÃªnero & Direito ◽

10.22478/ufpb.2179-7137.2019v8n6.49292 ◽

2019 ◽

Vol 8 (6) ◽

Author(s):

Svetlana A. Fadeeva ◽

Irina D. Sitdikova ◽

Elmira N. Mingazova ◽

Farit W. Khuzikhanov ◽

Veniamin A. Berezin ◽

...

Keyword(s):

Carcinogenic Risk ◽

The Body ◽

Industrial City ◽

Industrial Enterprises ◽

Environmental Objects ◽

Carcinogenic Effects ◽

Chemical Factors ◽

Hazard Indexes ◽

Expected Increase

We studied the quality of three environmental objects of the population living in a large industrial city (atmospheric air, soil and drinking water). We also determined the content and quantity of chemicals in the habitat of the population living near large industrial enterprises. We presented the results of the calculations of hazard indexes (HI), on the basis of which we derived the risk features of the development of non-carcinogenic effects of exposure to the body of chemical compounds (with combined and complex exposure). Non-carcinogenic risk is defined as an indicator of the expected increase in the incidence of the population due to the toxic properties of foreign chemicals in the studied environmental objects. The main objective of our socio-hygienic study was to identify chemical factors in the environment that are potentially hazardous to the life and health of children and adults living within a radius of 4,800 meters from an industrial enterprise in a large industrial city when received in different ways (combined) and assess the risk of violations in human health of varying severity when exposed to non-carcinogenic chemicals

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