scholarly journals A Case Study depicting Management of Diabetes Mellitus with Autologous Stem Cells

2017 ◽  
Vol 1 (1) ◽  
Keyword(s):  
Diabetes Mellitus ◽  
Stem Cells ◽  
Peptide Hormone ◽  
The Body ◽  
Anabolic Hormone ◽  
Main Culprit ◽  
Fat Liver

Diabetes mellitus type 2 is a long-term disorder of the metabolism characterized by elevated levels of sugar in blood, insulin resistance, and relative lack of insulin. Insulin is the main culprit for diabetes mellitus. Beta cells of the pancreatic islets are the producers of this peptide hormone which is considered to be the main anabolic hormone of the body regulating the carbohydrates, fats and protein metabolism by promoting the absorption of, especially, glucose from the blood into fat, liver and skeletal muscle cells. From this study, it seems that stem cell therapy can be a promising approach to manage the long term condition diabetes mellitus. The patients were administered stem cells derived from their bone marrows during the procedure. The levels of blood glucose and glycated hemoglobin (HbA1c) were decreased significantly post procedure in both the patients.

scholarly journals Impact of Diabetes Mellitus on Human Erythrocytes: Atomic Force Microscopy and Spectral Investigations

2018 ◽  
Vol 15 (11) ◽  
pp. 2368 ◽  
Author(s):  
Mohamad S. AlSalhi ◽  
Sandhanasamy Devanesan ◽  
Khalid E. AlZahrani ◽  
Mashael AlShebly ◽  
Fatima Al-Qahtani ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Atomic Force Microscopy ◽  
Present Report ◽  
The Body ◽  
Diabetic Patients ◽  
Force Microscopy ◽  
Atomic Force ◽  
Sugar Levels

Diabetes mellitus (DM) is a common metabolic disease indicated by high sugar levels in the blood over a prolonged period. When left untreated, it can lead to long-term complications, such as cardiovascular disease, stroke, and diabetic retinopathy or foot ulcers. Approximately 415 million people (about 8.3% of the world’s population) had diabetes worldwide in 2015, with 90% of the cases classified as Type 2 DM, which is caused by insulin resistance that arises mostly from being overweight and from a lack of exercise. DM affects every part of the body, including the erythrocytes. The aim of the present report is to gain insight into the damage done to the erythrocytes of patients classified with pre-diabetes and diabetes (plenty are found in the Kingdom of Saudi Arabia, a country where young people encompass a large segment of the population). The study presents results on the morphological analysis of erythrocytes by atomic force microscopy (AFM) and molecular investigations by fluorescence spectroscopy (FS). Our results indicate significant differences (in the morphology, size, and hemolytic end products) between the erythrocytes of diabetic patients (HbA1C, glycated hemoglobin, levels of 8–10%) and normal controls. It is well-known that DM and smoking are two major contributory factors for cardiovascular diseases (CVDs), and our observations presented in this study suggest that diabetes plays a relatively less damaging role than smoking for CVD.

Penerapan Senam Kaki Diabetik Untuk Menurunkan Kadar Gula Darah Pada Pasien Diabetes Melitus Tipe 2

2021 ◽  
Vol 1 ◽  
pp. 1686-1690
Author(s):  
M. Zakky Febriyan ◽  
I Isytiaroh
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Blood Sugar ◽  
Diabetic Foot ◽  
Health Workers ◽  
The Body ◽  
Sugar Levels

AbstractDiabetes mellitus is a condition of increasing blood sugar levels that exceed 140 mg/dl. The purpose of this case study is to describe the application of giving diabetic foot exercises to reduce blood sugar levels in the body in patients with type 2 diabetes mellitus. The design of this scientific paper uses a case study method with 2 clients suffering from type 2 diabetes mellitus with blood sugar above 140 mg. /dl in Poncol Village and in Karangsari Village, Batang Regency. The intervention carried out was giving diabetic foot exercises for 4 days and once a day. Evaluation was carried out to determine the decrease in blood glucose using a glucometer. The results of the study showed a decrease in blood sugar in both clients, for client 1 there was a decrease in blood sugar from 220mg/dl to 135mg/dl and for client 2 there was a decrease in blood sugar from 250mg/dl to 137mg/dl. The conclusion of this case study shows that diabetic foot exercises can reduce blood sugar levels in patients with type 2 diabetes mellitus. Suggestions for health workers are expected to teach diabetic foot exercises to reduce blood sugar levels in patients with type 2 diabetes mellitus.Keywords: blood sugar, diabetes mellitus, foot exercise AbstrakDiabetes mellitus merupakan kondisi kenaikan kadar gula darah yang melebihi 140mg/dl. Tujuan dari studi kasus ini adalah menggambarkan penerapan pemberian senam kaki diabetik untuk menurunkan kadar gula darah dalam tubuh pada penderita diabetes mellitus tipe 2. Rancangan karya tulis ilmiah ini menggunakan metode studi kasus dengan subjek 2 klien yang menderita diabetes mellitus tipe 2 dengan gula darah diatas 140mg/dl di Desa Poncol dan di Desa Karangsari Kabupaten Batang. Intervensi yang dilakukan adalah pemberian tindakan senam kaki diabetik selama 4 hari dan dilakukan satu kali sehari. Evaluasi dilakukan untuk mengetahui penurunan glukosa darah menggunakan alat ukur glukometer Hasil studi menunjukan adanya penurunan gula darah dalam tubuh pada kedua klien, untuk klien 1 mengalami penurunan gula darah dari 220mg/dl menjadi 135mg/dl dan untuk klien 2 mengalamai penurunan gula darah dari 250mg/dl menjadi 137mg/dl. Simpulan studi kasus ini menunjukan bahwa senam kaki diabetik mampu menurunkan kadar gula darah pada penderita diabetes mellitus tipe 2. Saran bagi tenaga kesehatan diharapkan mengajarkan senam kaki diabetik untuk menurunkan kadar gula darah pada penderita diabetes mellitus tipe 2. Kata kunci : diabetes mellitus, gula darah, senam kaki

Serum Ferritin Status of Patients with Type 2 DM Attending OPD of BIRDEM General Hospital

2020 ◽  
Vol 11 (1) ◽  
pp. 7-10
Author(s):  
Khadiza Begum ◽  
Fahmida Islam ◽  
Farjana Aktar ◽  
Murshida Aziz ◽  
Tohfa E Ayub Tahiya
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Serum Ferritin ◽  
Study Groups ◽  
Acute Phase Reactant ◽  
The Body ◽  
Iron Stores ◽  
Normal Healthy Individual ◽  
Diabetes Patients

Background: In recent times much is talked about of serum ferritin, an acute phase reactant a marker of iron stores in the body and its association with diabetes mellitus. Studies implicate that increased body iron stores and subclinical hemochromatosis has been associated with the development of glucose intolerance, type 2 diabetes and its micro as well as macrovascular complications. Material & Methods: This study was carried out to examine and to observe for any relationship between serum ferritin with Type 2 diabetes mellitus. Our study populations were included 163. Among them 81 type 2 diabetes patients as a case (M=49,F=32, mean 44.68 age in years)and 82 normal healthy individual as a control ( M=35, F=47 , mean 34.71 in years). Results: Majority were healthy outpatients who had come for regular checkup and were matched with controls. Serum ferritin and FBS were estimated and other investigations. Results showed that although Serum ferritin was in the normal range value it was increased in type 2 diabetes patients than in controls and was statistically significant, we did get a positive correlation with duration of diabetes. It can be concluded that there were positive associations between serum ferritin and FBG, age, sex among study groups. Conclusion: In conclusion our study shows that there is significant correlation between increased serum ferritin in diabetes compared to individuals with normal blood sugars in this part and hyper ferritinemia may be one of the causes for development of insulin resistance before overt diabetes. Anwer Khan Modern Medical College Journal Vol. 11, No. 1: Jan 2020, P 7-10

Long-Term Efficacy and Safety of Ertugliflozin in Patients (Pts) with Type 2 Diabetes Mellitus (T2DM) Inadequately Controlled with Metformin (MET) Monotherapy—104-Week VERTIS MET Trial

Diabetes ◽  
2018 ◽  
Vol 67 (Supplement 1) ◽  
pp. 1129-P
Author(s):  
SILVINA GALLO ◽  
BERNARD CHARBONNEL ◽  
ALLISON GOLDMAN ◽  
HARRY SHI ◽  
SUSAN HUYCK ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Efficacy And Safety ◽  
Term Efficacy
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