38. Mold by the Numbers: The Strengths and Weaknesses of the Scientific Literature to Provide Mycotoxin-related IAQ Risk Assessment

2004 ◽  
Author(s):  
M. Lumpkin ◽  
D. Dahlstrom
Keyword(s):  
Risk Assessment ◽  
Scientific Literature

scholarly journals Using Heinrich’s (Bird’s) Pyramid of Adverse Events to Assess the Level of Safety in an Airline

2021 ◽  
Vol 0 (0) ◽  
Author(s):  
Juris Maklakovs ◽  
Aleksandrs Bitins ◽  
Ruta Bogdane ◽  
Vladimir Shestakov
Keyword(s):  
Risk Assessment ◽  
Adverse Events ◽  
Causal Relationship ◽  
Scientific Literature ◽  
Emergency Situation ◽  
Flight Safety ◽  
Key Concepts ◽  
Risk Matrices

Abstract One of the key concepts in matters of flight safety is that of special (abnormal) situations, with airworthiness regulation and certification of aviation equipment being based on this concept. At the same time, one is forced to admit that today there is no explicit interpretation of the standardized traits of special situations, nor are they not fully elucidated in the scientific literature. In this article we propose a pyramid-based approach to interpreting special (abnormal) in-flight situations, which allows for risk assessment not using risk matrices, but instead relying only on the probabilistic characteristics of the occurrence of events. Using the presence of a causal relationship between the layers of the pyramid, we propose an algorithm for the transition of varying degrees of danger of special situations. This algorithm can be used to develop an on-board device that informs the pilot about the dynamics of transitions from one situation to another, representing each emergency situation in a certain color.

scholarly journals Genetic testing for choroideremia

2017 ◽  
Vol 1 (s1) ◽  
pp. 26-28
Author(s):  
Andi Abeshi ◽  
Alessandra Zulian ◽  
Tommaso Beccari ◽  
Munis Dundar ◽  
Francesco Viola ◽  
...  
Keyword(s):  
Risk Assessment ◽  
Clinical Trials ◽  
Optical Coherence Tomography ◽  
Differential Diagnosis ◽  
Clinical Utility ◽  
Scientific Literature ◽  
Genetic Test ◽  
Fundus Autofluorescence ◽  
Clinical Findings ◽  
Ophthalmological Examination

Abstract We studied the scientific literature and disease guidelines in order to summarize the clinical utility of the genetic test for choroideremia (CHM). CHM is an inherited X-linked recessive disorder associated with variations in the CHM gene. The overall prevalence of CHM varies from 1 in 50 000 to 1 in 100 000. Clinical diagnosis is based on clinical findings, ophthalmological examination, visual field, fundus autofluorescence, optical coherence tomography and electroretinography. The genetic test is useful for confirming diagnosis and for differential diagnosis, couple risk assessment and access to clinical trials.

scholarly journals Genetic testing for color vision deficiency

2017 ◽  
Vol 1 (s1) ◽  
pp. 32-34
Author(s):  
Andi Abeshi ◽  
Alice Bruson ◽  
Tommaso Beccari ◽  
Munis Dundar ◽  
Leonardo Colombo ◽  
...  
Keyword(s):  
Risk Assessment ◽  
Genetic Testing ◽  
Color Vision ◽  
Clinical Utility ◽  
Autosomal Dominant ◽  
Scientific Literature ◽  
Genetic Test ◽  
Clinical Findings ◽  
Color Vision Deficiency ◽  
Dark Adaptometry

Abstract We studied the scientific literature and disease guidelines in order to summarize the clinical utility of genetic testing for color vision deficiency (CVD). Deuteranopia affects 1 in 12 males and is inherited in an X-linked recessive manner. It is associated with variations in the OPN1LW (OMIM gene: 300822; OMIM disease: 303900) and OPN1MW (OMIM gene: 300821; OMIM disease: 303800) genes. Tritanopia has a prevalence of 1 in 10 000, is inherited in an autosomal dominant manner, and is related to variations in the OPN1SW (OMIM gene: 613522; OMIM disease: 190900) gene. Blue cone monochromatism has a prevalence of 1 in 100 000, is inherited in an X-linked recessive manner and is related to mutations in the OPN1LW (OMIM gene: 300822; OMIM disease: 303700) and OPN1MW (OMIM gene: 300821; OMIM disease: 303700) genes. Clinical diagnosis is based on clinical findings, ophthalmogical examination, family history, electroretingraphy, color vision testing and dark adaptometry. The genetic test is useful for confirming diagnosis, and for differential diagnosis, couple risk assessment and access to clinical trials.

scholarly journals Genetic testing for Mendelian myopia

2017 ◽  
Vol 1 (s1) ◽  
pp. 74-76
Author(s):  
Andi Abeshi ◽  
Pamela Coppola ◽  
Tommaso Beccari ◽  
Munis Dundar ◽  
Leonardo Colombo ◽  
...  
Keyword(s):  
Risk Assessment ◽  
Genetic Testing ◽  
Clinical Utility ◽  
Autosomal Recessive ◽  
Autosomal Dominant ◽  
Scientific Literature ◽  
Genetic Test ◽  
Clinical Findings ◽  
Ophthalmological Examination ◽  
Recessive Transmission

Abstract We studied the scientific literature and disease guidelines in order to summarize the clinical utility of genetic testing for Mendelian myopia (MM), a large and heterogeneous group of inherited refraction disorders. Variations in the SLC39A5, SCO2 and COL2A1 genes have an autosomal dominant transmission, whereas those in the LRPAP1, P3H2, LRP2 and SLITRK6 genes have autosomal recessive transmission. The prevalence of MM is currently unknown. Clinical diagnosis is based on clinical findings, family history, ophthalmological examination and other tests depending on complications. The genetic test is useful for confirming diagnosis, and for differential diagnosis, couple risk assessment and access to clinical trials.

scholarly journals Genetic testing for lymphedema-distichiasis syndrome

2018 ◽  
Vol 2 (s1) ◽  
pp. 13-15
Author(s):  
Yeltay Rakhmanov ◽  
Paolo Enrico Maltese ◽  
Stefano Paolacci ◽  
Carla Marinelli ◽  
Matteo Bertelli
Keyword(s):  
Risk Assessment ◽  
Clinical Trials ◽  
Differential Diagnosis ◽  
Genetic Testing ◽  
Clinical Utility ◽  
Autosomal Dominant ◽  
Scientific Literature ◽  
Genetic Test ◽  
Double Row ◽  
Primary Lymphedema

AbstractWe studied the scientific literature and disease guidelines to summarize the clinical utility of genetic testing for lymphedema distichiasis (LD) syndrome. LD is inherited in an autosomal dominant manner, and has unknown prevalence. It is caused by variations in the FOXC2 gene. Clinical diagnosis involves clinical examination, targeted at identifying primary lymphedema (chronic swelling of the extremities) and distichiasis (double row of eyelashes). The genetic test is useful for confirming diagnosis, as well as for differential diagnosis, couple risk assessment and access to clinical trials.

scholarly journals The problem of rationing escape routes in pre-trial detention centers

2021 ◽  
Vol 263 ◽  
pp. 02012
Author(s):  
Aleksandr Parfenenko ◽  
Artem Komrakov
Keyword(s):  
Risk Assessment ◽  
Fire Safety ◽  
Large Scale ◽  
Scientific Literature ◽  
Working Hours ◽  
Assessment Methodology ◽  
Detention Centers ◽  
Key Factor ◽  
Risk Assessment Methodology

The article discusses the basic requirements for buildings and structures. The review of the scientific literature on fire safety revealed the lack of accounting for the working hours of pre-trial detention centers, as well as the influence of the employees of the institution. The existing risk assessment methodology is not applicable to such buildings, since the key factor in ensuring the safety of people is the time when the evacuation of people begins. The lack of standards and methods related to the risk assessment of buildings of pre-trial detention centers creates the need for large-scale experiments on the evacuation of people.

Oil spill modeling

2017 ◽  
Vol 42 (1) ◽  
pp. 112-127 ◽  
Author(s):  
Jake R Nelson ◽  
Tony H Grubesic
Keyword(s):  
Risk Assessment ◽  
Oil Spill ◽  
Scientific Literature ◽  
Research Effort ◽  
Progress Report ◽  
Oil Spill Modeling ◽  
Significant Research ◽  
Future Work ◽  
Analytical Approaches ◽  
Community Systems

Oil spill modeling is fundamental for planning and preparing for, as well as responding to and mitigating, actual spill events. As a result, significant research effort has been directed toward developing analytical approaches for deepening our understanding of spill risk, community vulnerability, oil behavior, spill outcomes, and impacts. The purpose of this paper is to provide a synthesis of the oil spill risk assessment and impact modeling literature, with a focus on the vulnerability of local environmental, ecological, and community systems, as well as the geographic processes associated with modeling spills and transforming these data into a robust and meaningful impact assessments. The results of this progress report reveal a number of methodological and substantive commonalities across the scientific literature. Moreover, the synthesis of this literature should provide researchers with a strong foundation for pursuing future work in this domain.

scholarly journals Information on which to base assessments of risk from environments contaminated with anthrax spores

1994 ◽  
Vol 113 (3) ◽  
pp. 479-490 ◽  
Author(s):  
A. Watson ◽  
D. Keir
Keyword(s):  
Risk Assessment ◽  
Bacillus Anthracis ◽  
Causative Agent ◽  
Scientific Literature ◽  
Health Hazards ◽  
Environmental Materials ◽  
Anthrax Spores ◽  
Available Information

SUMMARYAlthough there has been a considerable amount of research conducted intoBacillus anthracis, the causative agent of anthrax, the data are widely disseminated in the scientific literature and are therefore not always easy to assimilate. In view of continuing concern about potential anthrax contamination in environmental materials and sites, this review brings together the currently available information relating to the health hazards fromB. anthracis.The relevance of the available information for risk assessment purposes is assessed.

Sign in / Sign up

Export Citation Format

Share Document