scholarly journals Prevalence of rotavirus infection and its association with socio-demographic characteristics among under-five children admitted with acute diarrhoea in a tertiary care hospital of Bangladesh

2021 ◽  
Vol 11 (3) ◽  
pp. 186-190
Author(s):  
Farjana Binte Habib ◽  
Mohammed Mirazur Rahman ◽  
Rafaat Choudhury ◽  
Tarun Kanti Paul ◽  
Md Moynul Haque
Keyword(s):  
Tertiary Care ◽  
Acute Diarrhoea ◽  
Watery Diarrhoea ◽  
Enzyme Linked Immunosorbent Assay ◽  
High Morbidity ◽  
Care Hospital ◽  
Cross Sectional ◽  
Rotavirus Infection ◽  
Under Five ◽  
Under Five Children

Background: Rotavirus has been recognized as the most common cause of acute watery diarrhoea among under-five children worldwide. It is considered as a major cause of childhood morbidity and mortality particularly in developing countries like Bangladesh. Considering the high morbidity and significant mortality, this study was designed to evaluate the prevalence of rotaviral diarrhoea among children less than five years in Sylhet region of Bangladesh. Methods: This cross-sectional study was conducted in the Department of Microbiology, Sylhet MAG Osmani Medical College from 1st January to 31st December, 2018. Total 184 under-five children admitted in paediatrics department of the same institute with acute watery diarrhoea were enrolled in this study by convenient sampling. Stool samples were obtained and assayed for rotavirus antigen by sandwich type enzyme linked immunosorbent assay (ELISA). Results: Rotaviral antigen was found positive in 86 cases and disease prevalence was 46.74%. The rotavirus infection was found highest in age group of 7 to 12 months (50.56%) and in male (59.30%) children. Prevalence of infection was associated with age (p= 0.004), socio-economic condition (p=0.001) and exclusive breastfeeding of children (p=0.01). Conclusion: Rotavirus was a significant cause of acute watery diarrhoea and mainly affected children below 12 months age. BIRDEM Med J 2021; 11(3): 186-190

scholarly journals A Comparative Study of Rotaviral Antigen Detection by ELISA and ICT in Children below Five Years with Acute Diarrhoea in A Tertiary Care Hospital

2021 ◽  
Vol 49 (1) ◽  
pp. 14-18
Author(s):  
Farjana Binte Habib ◽  
Mohammed Mirazur Rahman ◽  
Md Moynul Haque ◽  
Shib Prasad Sinha ◽  
Suborna Dey ◽  
...  
Keyword(s):  
Rapid Detection ◽  
Tertiary Care ◽  
Significant Proportion ◽  
Antigen Detection ◽  
Watery Diarrhoea ◽  
Enzyme Linked Immunosorbent Assay ◽  
Care Hospital ◽  
Rotavirus Infection ◽  
Under Five ◽  
Stool Samples

Rotavirus is responsible for acute severe watery diarrhoea in young children. Early and rapid detection of rotavirus infection can help to reduce inappropriate administration of antibiotics and has future positive impact on prevention of drug resistance. This cross-sectional study was designed to determine the role of rotaviral antigen detection by ICT from stool sample of acute diarrhoeal children below five years admitted in Sylhet MAG Osmani Medical College Hospital, Sylhet and was carried out in the department of microbiology in collaboration with the department of paediatrics during the period from 1st January  to 31st December, 2018. Total 184 children of under five years of age with acute watery diarrhoea were enrolled in this study. Rotaviral antigen was detected by ELISA (Enzyme Linked Immunosorbent Assay) and ICT (Immunochromatographic test) from stool samples. Out of 184 stool samples, rotaviral antigen was found positive in 84 and 86 cases by ICT and ELISA methods, respectively. ICT showed sensitivity of 90.70% and specificity of 93.88% when compared with ELISA. The rotavirus infection was found highest in male children (61.90%) and in age group of 7 to 12 months (51.89%). Considering the importance of rotaviral diarrhoea, rapid detection of rotavirus infection by ICT is essentially needed and should be practiced routinely as it is relatively reliable, easy to perform and cost-effective. It is particularly important in Bangladesh, where diarrhoea is still contributing a significant proportion of mortality and morbidity in under five children. Bangladesh Med J. 2020 Jan; 49 (1): 14-18

scholarly journals Rotavirus in diarrhoeic children under-five attending a tertiary care hospital in Mumbai, India

2018 ◽  
Vol 5 (5) ◽  
pp. 1863
Author(s):  
Nikhil Khude ◽  
Lona Dash ◽  
Sushma Save ◽  
Badhuli Samal ◽  
Jayanthi Shastri
Keyword(s):  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Acute Diarrhoea ◽  
Enzyme Linked Immunosorbent Assay ◽  
Care Hospital ◽  
Etiological Diagnosis ◽  
Under Five ◽  
Under Five Children ◽  
Stool Samples ◽  
Parasitic Pathogens

Background: Diarrhoeal diseases are a leading cause of morbidity and mortality among children requiring hospitalization in developing countries. Rotavirus is the most common cause of acute diarrhoea among under-five children. Etiological diagnosis of diarrhoea would enable appropriate management of patients while limiting the spread of drug resistant pathogens. This study was undertaken to determine presence of rotavirus and other diarrhoeal pathogens in under-five diarrhoeic children attending a tertiary care hospital, and the related clinical presentations.Methods: 120 stool samples of under-five children with acute diarrhoea, attending the OPD and indoor services of a tertiary care hospital, were studied over one year. Rotavirus antigen was detected using enzyme linked immunosorbent assay. Bacterial and parasitic pathogens were detected using standard microbiological techniques.Results: Out of 120 stool samples tested, 36 were positive for Rota virus antigen. Bacterial isolates included E. coli (25), Vibrio cholerae (12) and Aeromonas species (1). Parasites were observed in nine samples and multiple pathogens in nine.Conclusions: Rotavirus continues to be a major cause of childhood diarrhoea. As antibiotics have no role in the management of viral and parasitic diarrhoeas, etiological diagnosis is imperative for proper management of diarrhoea and prevention of indiscriminate use of antibiotics.

scholarly journals Isolation of Campylobacter Species in the Stool of Under Five Children With Acute Diarrhea in a Tertiary Care Hospital of Bangladesh

2021 ◽  
Vol 49 (3) ◽  
pp. 11-16
Author(s):  
Suborna Dey ◽  
Rajib Das ◽  
Md Moynul Haque ◽  
Premananda Das ◽  
Shantanu Das ◽  
...  
Keyword(s):  
Acute Diarrhea ◽  
Tertiary Care ◽  
Acute Diarrhoea ◽  
Socioeconomic Background ◽  
Care Hospital ◽  
Age Group ◽  
Isolation Rate ◽  
Under Five ◽  
Under Five Children ◽  
Campylobacter Species

Campylobacter species is the main etiology of gastroenteritis due to bacteria.  To determine prevalence of Campylobacter species in stool of children less than five years of age with acute diarrhoea, this observational study was conducted in the Department of Microbiology, Sylhet M A G Osmani Medical College, Sylhet from January to December, 2017. Stool samples were collected from 162 under-five children with acute diarrhoea admitted in the Department of Paediatrics. Isolation of Campylobacter species were done by stool culture. About two third of the children were male (65.4%) and more than one fourth of the affected children (26.65%) were in age group 6-12 months. Campylobacter species was isolated in 24 (15%) sample and among them, Campylobacter jejuni were 22 (91.7%) and Campylobacter coli were 2 (8.3%). Isolation rate of Campylobacter species did not differ significantly between age group of 6-12 months and  above 12 months (p=0.211) of age;  male and female children (p=0.288); among socioeconomic status (p=0.673) and between residential status (p=0.108). Isolation rate of Campylobacter species are frequent among under five children with acute diarrhea and most of the children came from low socioeconomic background and were male. However, a large multicenter study needs to be conducted to generate more evidence regarding the issue. Bangladesh Med J. 2020 Sept; 49(3) : 11-16

scholarly journals Knowledge, Attitude and Practice of Using ORS and Household Management of Childhood Diarrhoea

2019 ◽  
Vol 38 (2) ◽  
pp. 94-101
Author(s):  
Naresh Chandra Acharya ◽  
Dillip Kumar Dash ◽  
Mamata Devi Mohanty ◽  
Priyanka Agarwal ◽  
Pratik Dey
Keyword(s):  
Tertiary Care ◽  
Acute Diarrhoea ◽  
Childhood Mortality ◽  
Background Information ◽  
Treatment Modalities ◽  
Care Hospital ◽  
Under Five ◽  
Under Five Children ◽  
Attitude And Practice ◽  
Knowledge Attitude And Practice

Introduction: Diarrhoea is defined as the passage of three or more loose stools per day. Diarrhoea is one of the leading causes of childhood mortality in India. The objectives of the study were to assess household Knowledge, Attitude and Practice for prevention of Diarrhoea in children through preformed questionnaires. Material and Methods: Four hundred and sixty eight under five children were selected for study by Cluster sampling method. Background information, details of acute diarrhoea and treatment modalities were obtained from mother of the under five children. This was a hospital based study conducted at a tertiary care hospital, from 1st May 2017 to 30th December 2017. Results: About 70% of the moms were between the age assemble 25-32 years and the vast majority of them were housewives (72%). A greater part (>66%) of the moms were having essential/auxiliary education. Learning with respect to different parts of the diarrhoea and ORS surprisingly extremely unacceptable. In the present examination it is seen that learning in regards to ORS in looseness of the bowels is more in educated mother than uneducated. Three sitting of Educational mediations realized huge enhancement of the middle scores of learning, state of mind and practice expanded from 9, 6, 3 to 19, 14, 8, individually, Conclusion: The household knowledge regarding method of use and preparation of ORS for management of diarrhoea was observed to be lacking in this investigation. More estimates should be taken to enhance this learning and make moms mindful about the planning and utilization of ORS.  

Clinical Profile and Characterization of Rotavirus Strains in Under-Five Children with Diarrhea: A Hospital-Based Study from Eastern Odisha, India

2022 ◽  
Author(s):  
J Bikrant Kumar Prusty ◽  
Jasashree Choudhury ◽  
Goolla Akhila ◽  
Mrutunjay Dash ◽  
Mamata Devi Mohanty ◽  
...  
Keyword(s):  
Tertiary Care ◽  
Clinical Profile ◽  
Categorical Variables ◽  
Care Hospital ◽  
Isolation And Identification ◽  
Surveillance Network ◽  
Rotavirus Infection ◽  
Under Five ◽  
Under Five Children ◽  
Prevalent Strain

Abstract Objective Diarrheal diseases are one of the most common causes of hospitalization in children under five. Rotavirus is the most common cause of acute diarrhea in younger children, and the prevalence decreases rapidly with increasing age. The objective of the study was to estimate the burden of rotavirus infection in acute gastroenteritis among under-five children admitted to a tertiary care hospital in eastern Odisha, for the clinical profile and identity of the prevalent strains. Methods This was a prospective observational study linked to the National Rotavirus Surveillance Network (NRSN), where 720 under-five children with diarrhea were enrolled. In total, 675 stool samples of eligible candidates were sent for rotavirus isolation, and identification of strains was done by identifying VP7 (G-type) and VP4 (P-type) genes by reverse transcription polymerase chain reaction. Results Categorical variables were presented as frequency and percentage, and continuous variables were expressed as mean ± standard deviation. Rotavirus was detected in 256 (37.92%) samples. Males outnumbered females. The most common affected age group was 7 to 12 months, followed by 13 to 18 months. G3P[8] was the most prevalent strain in this study. Conclusion Children between the age of 7 and 18 months were most vulnerable to rotavirus infection. The most prevalent strain varies from one region to another and continuous surveillance is needed.

scholarly journals Exclusive breast feeding reduces diarrhoeal episodes among children: results from a cross-sectional study among the mothers of under-five children in Kolkata

2019 ◽  
Vol 6 (2) ◽  
pp. 733 ◽  
Author(s):  
Nibedita Banerjee ◽  
Arup Chakraborty ◽  
Arista Lahiri ◽  
Kalidas Biswas
Keyword(s):  
Breast Feeding ◽  
Nuclear Family ◽  
Tertiary Care ◽  
Child Growth ◽  
Care Hospital ◽  
Cross Sectional ◽  
Exclusive Breast Feeding ◽  
Under Five ◽  
Under Five Children ◽  
The Mean

Background: Breast feeding is of utmost importance for optimal child growth. This study aims to determine the knowledge on breast feeding among the mothers of under five children and to find out the association between the proportion of exclusive breast feeding and the incidence of diarrhoeal disease.Methods: An institution based cross sectional descriptive study was conducted among ninety (90) mothers of under five children who attended the immunization clinic of a tertiary care hospital with the help of a pre-designed, pre-tested, semi-structured schedule. Mothers were selected by systematic random sampling and interview done after obtaining written consent.Results: The mean age of the respondent mothers were 25.78 years. Among them 77.8% were staying in the nuclear family with the mean education up to 8th standard, 94.4% of home maker. The mean education of fathers was 9th standard with majority (77.8%) occupied either in service or in other occupation. Average no of children per family was 1.3. Majority of mothers’ younger children (66.7%) were male. Majority (66.7%) mothers had heard the term colostrum and 88.3% knew that colostrum has anti-infective property and nutritionally superior. Sixty (66.67%) mothers had exclusively breast fed their children. Out of not exclusively breastfed children 36.67% experienced diarrhoea.Conclusions: Though majority mothers knew about breastfeeding, yet the proportion not having proper knowledge was high. The statistical analysis showed exclusive breast feeding to be highly protective against developing diarrhoeal episodes. In order to generate better breastfeeding practices, addressing the knowledge gap is needed. 

scholarly journals Evaluation of Risk Factors Associated with Rotaviral Diarrhoea among Under Five Children in Sylhet Region of Bangladesh

2019 ◽  
Vol 48 (2) ◽  
pp. 32-37
Author(s):  
Farjana Binte Habib ◽  
Mohammed Mirazur Rahman ◽  
Md Moynul Haque ◽  
Probhat Ranjan Dey ◽  
Premananda Das ◽  
...  
Keyword(s):  
Risk Factors ◽  
Cross Sectional Study ◽  
Bottle Feeding ◽  
Watery Diarrhoea ◽  
Enzyme Linked Immunosorbent Assay ◽  
College Hospital ◽  
Cross Sectional ◽  
Under Five ◽  
Factors Associated ◽  
Under Five Children

Retrovirus is the major cause of acute severe diarrhea in under five children and contributing 10,000 to 27000 deaths each year in Bangladesh. This cross-sectional study was designed to determine the risk factors associated with Rotaviral among under five children admitted in the Department of Paediatrics, Sylhet MAG Osmani Medical College Hospital, Sylhet and was carried out in the Department of Microbiology during the period from 1st January to 31st December, 2018. Total 184 under five children with acute watery diarrhoea were enrolled in this study by convenient sampling. Stool samples were obtained and assayed for rotavirus antigens by enzyme linked immunosorbent assay (ELISA). Rotaviral antigen was found positive in 86 cases.The Rotavirus infection was found highest in age group of 7 to 12 months (50.56%) and in male (59.30%) children. It was found significantly higher in patients from lower socio-economic condition (64.00%), those who were from rural area (48.75%) and children who were not exclusively breastfed (83.87%). Bottle feeding, lower educational level of mother and overweight of children may serve as predisposing factors of rotavirus disease in these children. Bangladesh Med J. 2019 May; 48 (2): 32-37

scholarly journals Knowledge and practices of mothers of under-five children regarding Zinc supplementation in childhood diarrhea

2021 ◽  
Vol 11 (2) ◽  
pp. 301-304
Author(s):  
Meenal Kulkarni ◽  
Vedant Nayse ◽  
Jaydeep Nayse
Keyword(s):  
Analytical Study ◽  
Zinc Supplementation ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Care Hospital ◽  
Childhood Diarrhea ◽  
Cross Sectional ◽  
Under Five ◽  
Under Five Children ◽  
Socio Demographic Factors

Diarrhoea continues to plaque the developing worldresulting in morbidity of 1.7 billionand mortality of 5.25 lakhsin under- five childrenIn India diarrhea is 3 most common cause of death among under-five children with morbidity of 11.6 million and mortality of 1300 deaths and thus causing 8% of deaths per yearZinc has a major role in prevention of diarrhea. To assess the knowledge and practices of mothers of under-five children regarding zinc supplementation for prevention of childhood diarrhea, to find out the reasons for not supplementing Zinc during diarrhoeal episodes, to find out association between socio-demographic factors and awareness of zinc supplementation. : Hospital based cross sectional analytical study was conducted among 200 mothers of underfive children in outpatient department of Paediatrics of a tertiary care hospital. The data was entered in predesigned semistructured questionnaire. Data was analysed by EPI INFO 7 software. Only 18(9%) mothers were aware about use of Zn supplementation to the under-five children in childhood diarrhoea. Only 10 mothers administered zinc supplementation in childhood diarrhea. Unawareness regarding Zn supplement was common reason mentioned for not giving Zn supplementation. Association was found between religion, type of family and awareness of Zn supplementation. There is a need to increase awareness of mothers regarding zinc supplementation by conducting health education sessions.

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