scholarly journals Characterization of an Expectorant Herbal Basak Tea Prepared with Adhatoda vasica Leaves

1970 ◽  
Vol 44 (2) ◽  
pp. 211-214 ◽  
Author(s):  
Ashish K Sarker ◽  
Kabir Ahamed ◽  
Jasim Uddin Chowdhury ◽  
Jarifa Begum
Keyword(s):  
Petroleum Ether Extract ◽  
Analytical Data ◽  
Water Extract ◽  
Relaxation Effect ◽  
Hot Water ◽  
Herbal Tea ◽  
Adhatoda Vasica ◽  
Alcohol Extract ◽  
Toxicity Studies ◽  
Animal Toxicity

A herbal tea for an expectorant action was prepared with Adhatoda vasica leaves. Analytical, pharmacological, microbiological and animal toxicity studies were carried out to characterize the herbal tea. The analytical data indicates that the alcohol extract from herbal basak tea contains 0.67% crude alkaloids and the isolated tracheal chain experiment with this extract showed small relaxation effect compare to the standard histamine drug. The crude alkaloids and the other extracts (petroleum ether extract, alcohol extract and hot water extract) showed mild inhibition in different degrees against different microorganisms. The animal toxicity studies on rats revealed no mortality after 24 hours and also no abnormal delayed effect indicates no toxicity of prepared tea at all. Based on the above results, the prepared herbal basak tea is proposed as a good expectorant. Herbal tea prepared with Adhatoda vasica leaves collected in May to September showed better efficacy than those of other times. Key words: Herbal basak tea, Crude alkaloids, Relaxation effect. DOI: 10.3329/bjsir.v44i2.3674 Bangladesh J. Sci. Ind. Res. 44(2), 211-214, 2009

scholarly journals Acute and 13-week subchronic toxicity studies of hot-water extract of Cynanchi wilfordii Radix in Sprague-Dawley rats

2019 ◽  
Vol 36 (1) ◽  
pp. 89-98 ◽  
Author(s):  
Chung-Tack Han ◽  
Du-Yeol Kim ◽  
Chunja Nam ◽  
Seol-Hee Moon ◽  
Sun-Hee Park ◽  
...  
Keyword(s):  
Water Extract ◽  
Hot Water ◽  
Sprague Dawley ◽  
Subchronic Toxicity ◽  
Toxicity Studies ◽  
Sprague Dawley Rats ◽  
Hot Water Extract

scholarly journals Effect of Extracting Solvents on the Phyto-chemical Properties of Fermented Pawpaw (Carica papaya L.) Seed

2019 ◽  
pp. 1-10
Author(s):  
M. O. Adesola ◽  
E. A. Akande
Keyword(s):  
Petroleum Ether ◽  
Carica Papaya ◽  
Antioxidant Activities ◽  
Petroleum Ether Extract ◽  
Chemical Properties ◽  
Water Extract ◽  
Hot Water ◽  
Ether Extract ◽  
Aqueous Solvent ◽  
Phytochemical Compounds

Fruit seeds contain several phytochemical compounds which have been reported to show antiviral, anti-allergic, anti-inflammatory, anti tumor and antioxidant activities. Due to the varied chemical properties of these seeds, different solvents are used in the extraction. Therefore, this research was aimed at evaluating the effect of extracting solvents on the yield, phytochemical compounds and selected chemical properties of fermented pawpaw (Carica papaya) seed. Extracts from fermented T-solo variety of pawpaw seeds were obtained using petroleum ether, n-hexane and hot aqueous solvents using standard method. Analysis was carried out to determine some qualitative and quantitative phyto-chemical and some selected chemical composition (Peroxide Value PV and Thiobarbituric Acid Value TBA. Extracts’ yield were 26.00, 23.30 and 19.51% for petroleum ether, n-hexane and hot aqueous solvent, respectively. The result of quantitative analysis shows that all the phytochemicals were more abundant in petroleum ether extract. The PV and TBA of n-hexane, petroleum ether and hot water extract were 5.32, 4.52, 0.00 meq/kg and 0.87, 0.16, 0.09 μg/kg respectively. The PV and TBA obtained for petroleum ether extract were relatively low and         this implied that the extract will undergo little or no autoxidation or oxidative deterioration when used.

scholarly journals Pharmacological effects of Pugionium cornutum (L.) Gaertn. extracts on gastrointestinal motility are partially mediated by quercetin

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Chencan Su ◽  
Haoyu Li ◽  
Bang Chen ◽  
Cong Li ◽  
Chunxiao Zhang ◽  
...  
Keyword(s):  
Smooth Muscle ◽  
Smooth Muscle Cell ◽  
Muscle Cell ◽  
Gastrointestinal Motility ◽  
Calcium Influx ◽  
Cell Model ◽  
Petroleum Ether Extract ◽  
Functional Gastrointestinal Disorders ◽  
Water Extract ◽  
Relaxation Effect

Abstract Background The majority of global population suffer from various functional gastrointestinal disorders. Pugionium cornutum (L.) Gaertn. (PCG) is used to relieve indigestive symptoms in traditional Chinese medicine. However, little is known about the effects of bioactive components from PCG extracts on gastrointestinal motility. Methods Crude ethanol extract of PCG (EEP) was prepared from Pugionium cornutum (L.) Gaertn. Different solvents were used to prepare fine extracts from EEP, including water extract of PCG (WEP), petroleum ether extract of PCG (PEEP), dichloromethane extract of PCG (DEP) and ethyl acetate extract of PCG (EAEP). Smooth muscle cell model and colonic smooth muscle stripe model were used to test the bioactive effects and mechanisms of different PCG extracts on contraction and relaxation. Diverse chromatographic methods were used to identify bioactive substances from PCG extracts. Results EEP was found to promote the relaxation of gastric smooth muscle cell and inhibit the contraction of colonic smooth muscle strip. Among the fractions of EEP, EAEP mainly mediated the relaxation effect by stimulating intracellular calcium influx. Further evidences revealed that EAEP was antagonistic to acetylcholine. In addition, COX and NO-GC-PKC pathways may be also involved in EAEP-mediated relaxation effect. Quercetin was identified as a bioactive compound from PCG extract for the relaxation effect. Conclusion Our research supports the notion that PCG extracts promote relaxation and inhibits contraction of gastrointestinal smooth muscle at least partially through the effect from quercetin.

CHEMICAL INVESTIGATION AND BIOLOGICAL ACTIVITIES OF VERBESINA ENCELIOIDES

INDIAN DRUGS ◽  
2012 ◽  
Vol 49 (01) ◽  
pp. 38-42
Author(s):  
S. C Jain ◽  
◽  
R. Jain ◽  
R. Singh ◽  
E. Menghani
Keyword(s):  
Biological Activities ◽  
Radical Scavenging Activity ◽  
Petroleum Ether Extract ◽  
Radical Scavenging ◽  
Water Extract ◽  
Chloroform Extract ◽  
Ether Extract ◽  
Alcohol Extract ◽  
Antibacterial Screening ◽  
High Degree

From the petroleum ether extract of flowers, betulin, friedelin and lupeol were isolated for the first time along with six other known compounds viz. n-triacontane, ester of beta-sitosterol, tricosyl alcohol, taraxasterol, beta-amyrin etc. During antibacterial screening, water extract of seeds showed appreciable activity (IZ 12 mm) against Pseudomonas aeruginosa. Similarly, in antifungal screening, chloroform extract of flowers (IZ 30 mm) and alcohol extract of roots (IZ 29 mm) exhibited very pronounced inhibitory activity against Tricophyton rubrum. High degree of free radical scavenging activity (RC50= 70 mcg) on DPPH assay of the pet. ether extract of roots was demonstrated among all the tested fractions.

Physiological Activities of the Hot Water Extract from Eriobotrya japonica Lindl.

2009 ◽  
Vol 38 (8) ◽  
pp. 977-982 ◽  
Author(s):  
Yoo-Seok Jeong ◽  
Hee-Kyoung Jung ◽  
Kwang-Sup Youn ◽  
Myoung-Ok Kim ◽  
Joo-Heon Hong
Keyword(s):  
Water Extract ◽  
Hot Water ◽  
Eriobotrya Japonica ◽  
Hot Water Extract
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