Physiological Activities of the Hot Water Extract from Eriobotrya japonica Lindl.

AbstractTurmeric (Curcuma longa) is a widely used spice that has various biological effects, and aqueous extracts of turmeric exhibit potent antioxidant activity and anti-inflammatory activity. Bisacurone, a component of turmeric extract, is known to have similar effects. Oxidative stress and inflammatory cytokines play an important role in ethanol-induced liver injury. This study was performed to evaluate the influence of a hot water extract of C. longa (WEC) or bisacurone on acute ethanol-induced liver injury. C57BL/6 mice were orally administered WEC (20 mg/kg body weight; BW) or bisacurone (60 µg/kg BW) at 30 min before a single dose of ethanol was given by oral administration (3·0 g/kg BW). Plasma levels of aspartate aminotransferase and alanine aminotransferase were markedly increased in ethanol-treated mice, while the increase of these enzymes was significantly suppressed by prior administration of WEC. The increase of alanine aminotransferase was also significantly suppressed by pretreatment with bisacurone. Compared with control mice, animals given WEC had higher hepatic tissue levels of superoxide dismutase and glutathione, as well as lower hepatic tissue levels of thiobarbituric acid-reactive substances, TNF-α protein and IL-6 mRNA. These results suggest that oral administration of WEC may have a protective effect against ethanol-induced liver injury by suppressing hepatic oxidation and inflammation, at least partly through the effects of bisacurone.

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RELATIONSHIPS BETWEEN MILLING ENERGY AND HOT WATER EXTRACT VALUES OF MALTS FROM SOME MODERN BARLEYS AND THEIR PARENTAL CULTIVARS

Journal of the Institute of Brewing ◽

10.1002/j.2050-0416.1986.tb04461.x ◽

1986 ◽

Vol 92 (6) ◽

pp. 604-607 ◽

Cited By ~ 32

Author(s):

M. J. Allison

Keyword(s):

Water Extract ◽

Hot Water ◽

Hot Water Extract

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Antioxidant properties of hot water extracts from carpophore and spores of mushroom Ganoderma lucidum

Zbornik Matice srpske za prirodne nauke ◽

10.2298/zmspn1120279k ◽

2011 ◽

pp. 279-288 ◽

Cited By ~ 1

Author(s):

Anita Klaus ◽

Maja Kozarski ◽

Miomir Niksic

Keyword(s):

Antioxidant Activity ◽

Ganoderma Lucidum ◽

Antioxidant Properties ◽

Water Extract ◽

Reducing Power ◽

Hot Water ◽

Ferrous Ions ◽

Medicinal Mushrooms ◽

Water Extracts ◽

Hot Water Extract

Ganoderma lucidum (Leyss.:Fr.) Karst is one of the medicinal mushrooms, which possesses enviable antioxidant properties. Objective of this investigation was to evaluate antioxidant activity, reducing power, scavenging abilities on 1.1-diphenyl-2-picrylhydrazyl (DPPH) radicals and chelating effects on ferrous ions of hot water extracts obtained from carpophore and spores of this mushroom. Hot water extract from carpophore (Gl-I) showed high antioxidant activity of 85.7 ? 0.7%, at 10 mg/ml, while antioxidant activity of hot water extract from spores (Gl-Is) was 9.2 ? 0.3% at 10 mg/ml. Reducing power of Gl-I reached a plateau of 3.4 ? 0.1 at 20 mg/ml, and 0.3 ? 0.0 at 20 mg/ml for Gl-Is. At 10 mg/ml, scavenging ability on DPPH radicals of Gl-I increased to 96.8 ? 2.5%, whereas Gl-Is scavenged DPPH radicals by 69.6 ? 2.5% at 10 mg/ml. Gl-I chelated 81.6 ? 3.6 % of ferrous ions at 20 mg/ml, while the chelating effect of Gl-Is was 73.8 ? 1.7%. The antioxidative activities of hot water extracts from carpophore and spores of the mushroom G. lucidum were concentration dependent and increased with an increase in the concentration.

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