scholarly journals Comparative efficacy of analgesic and anaesthetic drugs for high epidural analgesia in black bengal goats

1970 ◽  
Vol 6 (1) ◽  
pp. 103-106 ◽  
Author(s):  
RA Runa ◽  
MA Hashim ◽  
MA Hossain ◽  
AAM Bhuyan ◽  
MS Alam

The effects of analgesic and anaesthetic drugs on high epidural analgesia in Black Bengal goats were investigated. The animals were divided into five groups (n=8) and a replication of 8 trials was performed in each group at least one week interval. Two percent (2%) lidocaine hydrochloride, 0.5% bupivacaine hydrochloride, 2% lidocaine hydrochloride with adrenaline, ketamine hydrochloride and diazepam were administered into lumbo-sacral (high epidural) space for high epidural analgesia. Bupivacaine hydrochloride significantly (P < 0.05) decreased respiration rates, rectal temperature, however, increased heart rates during high epidural analgesia with prolonged analgesia compared to other drugs. Lidocaine hydrochloride showed a rapid onset and excellent analgesia and did not produce any side effects whereas, diazepam exhibited delay onset with short duration of analgesia. It seems that 2% lidocaine hydrochloride is effective for high epidural analgesia in goats. Key words: Analgesics, anaesthetics, high epidural analgesia, goats DOI = 10.3329/bjvm.v6i1.1347 Bangl. J. Vet. Med. (2008). 6 (1): 103-106

Author(s):  
NS Lucky ◽  
MA Hashim ◽  
JU Ahmed ◽  
K Sarker ◽  
NM Gazi ◽  
...  

The present investigation was conducted to find out the effect of different analgesic drugs in sheep. A series of 30 analgesic trials (caudal epidural analgesia) were conducted in sheep with 2% lignocaine hydrochloride (LH), 2% lignocaine hydrochloride with adrenaline (LHA) and 0.5% bupivacaine hydrochloride (BH) in Veterinary Clinic, BAU, Mymensingh during January to April 2007. Analgesic injection was administered into low epidural space in 3 groups (A, B and C), each consisting of 10 apparently healthy sheep aged between 1 and 1.5 years. Effects of analgesic drugs on heart rate, respiration rate and rectal temperature were monitored. Heart rates significantly decreased but respiration rates decreased nonsignificantly and rectal temperature non significantly increased during low epidural analgesia with 0.5% BH. Heart rates and respiration rates increased significantly when 2% LH and 2% LHA were used. LH (2%) showed rapid spreading and was also free from any side effect. Duration of analgesia was prolonged with 2% LH compared to other analgesic drugs. Peak point of analgesia was more with 2% LHA as compare to other analgesic drugs. There was no significant difference between 0.5% BH and 2% LHA in terms of their analgesic effect. Drowsiness, tympany and shivering were observed when 0.5% BH was used. It appears from the present study that 2% LH was more effective in low epidural analgesia. Key words: Analgesia, peak point, low epidural, sheep DOI = 10.3329/bjvm.v5i1.1319 Bangl. J. Vet. Med. (2007). 5 (1 & 2): 77-80


1970 ◽  
Vol 7 (1) ◽  
pp. 53-56
Author(s):  
K Sarker ◽  
MA Hashim ◽  
MA Hossain ◽  
NS Lucky

Analgesic effects were conducted with 2% lignocaine hydrochloride (LH), 2% lignocaine hydrochloride with adrenaline (LHA) and 0.5% bupivacaine hydrochloride (BH) in calves of both sexes. Analgesic drugs were injected into caudal epidural space in 30 apparently healthy calves of below one year of age. A total of 30 analgesic trials were done, where heart rate, respiration rate and rectal temperature were monitored. Heart rate and respiratory rate significantly (P<0.05) decreased from preanalgesic values, during caudal epidural analgesia period with 0.5% bupivacaine hydrochloride. Heart rate increased significantly (P<0.001) from preanalgesic values when 2% lignocaine plus adrenaline was used. Only lignocaine hydrochloride showed a short onset, rapid spreading without having any side effect. Duration of analgesia was prolonged with 0.5% bupivacaine hydrochloride compared to other analgesic agent. Drowsiness, tympany and shivering were observed when 0.5% bupivacaine hydrochloride was used. Bupivacaine seemed to be better for longer duration of analgesia compared to lignocaine. But lignocaine hydrochloride may be used for rapid onset of analgesia in calves. Keywords: Analgesia; Onset; Caudal epidural; Calves DOI: 10.3329/jbau.v7i1.4798 J. Bangladesh Agril. Univ. 7(1): 53-56, 2009


2015 ◽  
pp. 80-85
Author(s):  
Van Anh Nguyen ◽  
Van Nhan Le ◽  
Nguyen Nhu Phuong Phan

Objectives: To investigate and evaluate the therapeutic effects of Hoe hoa tan II in the treatment of internal haemorroids grade I, II and III. Ingredients of the remedy include: Hoe Hoa (Styphonolonium japonicum), Chi xac (Fructus citri Aurantii), Hau phac (Magnolia offinalis), Tran bi (Citrus deliciosa Tenore), Thuong thuat (Atractylodes lancea), O mai (Armeniaca vulgaris Lamk), Cam thao (Clycyrrhiza uralensis), Duong quy (Radix Angelicae Sinensis). Subjects and methods: Randomised controlled study (RCT) has been conducted on 60 patients which were divided into two groups, i.e. the first 30 patient group were treated with Hoe hoa tan II remedy 20 g, and the second 30 patient group were treated with Daflon 500 mg in the course of 14 days. Results: Study showed that Hoe hoa tan II has helped improve symptoms of internal haemorroids grade I, II and III such as bleeding, anal exudation, pain, reducing the size of the haemorroid tissues. The remedy has been shown to have the most significant effect on relieving constipation which is typical in haemorroids. The study also revealed no unwanted effects caused by this formula. Conclusion: Hoe hoa tan II can be therapeutically used to treat internal haemorroids grade I, II and III without causing any serious side effects. Key words: Hoe hoa tan II, internal haemorroids grade I, II, III.


2016 ◽  
pp. 25-29
Author(s):  
Van Huy Tran ◽  
Thi Huyen Thuong Nguyen

Background: Data about efficacy of Tenofovir in patients of HBV –related cirrhosis in Vietnam was still limited. This study is aimed at: - evaluating the clinical, biochemical, virological and Child-Pugh score responses 3,6,9 months after Tenofovir therapy; - assessing possible side effects of tenofovir. Patients and methods: 40 patients with HBV-related cirrhosis were enrolled. All has received Tenofovir disoproxil fumarate 300mg/day. Follow-up after 3,6 and 9 months. Results: Anorexia, oedema and ascites were significantly improved after treatment. HBV DNA became undetectable in 92.5%, 94.55 and 100% after 3,6 and 9 months, respectively. Child- Pugh score was improved after treatment (5.94±0.22 after treatment vs 7.47±0.28 before treatment). Side effects were minors (nausea, vomiting). No case of increase in serum creatinine was found. Conclusion: Tenofovir showed effective and safe in patients of HBV-related cirrhosis. Key words: Cirrhosis, tenofovir, HBV. Key words: cirrhosis, tenofovir, HBV


Author(s):  
Mu Xu ◽  
Jiajia Hu ◽  
Jianqin Yan ◽  
Hong Yan ◽  
Chengliang Zhang

Abstract Objective Paravertebral block (PVB) and thoracic epidural analgesia (TEA) are commonly used for postthoracotomy pain management. The purpose of this research is to evaluate the effects of TEA versus PVB for postthoracotomy pain relief. Methods A systematic literature search was conducted in PubMed, EMBASE, Web of Science, and the Cochrane Library (last performed on August 2020) to identify randomized controlled trials comparing PVB and TEA for thoracotomy. The rest and dynamic visual analog scale (VAS) scores, rescue analgesic consumption, the incidences of side effects were pooled. Results Sixteen trials involving 1,000 patients were included in this meta-analysis. The pooled results showed that the rest and dynamic VAS at 12, 24, and rest VAS at 48 hours were similar between PVB and TEA groups. The rescue analgesic consumption (weighted mean differences: 3.81; 95% confidence interval [CI]: 0.982–6.638, p < 0.01) and the incidence of rescue analgesia (relative risk [RR]: 1.963; 95% CI: 1.336–2.884, p < 0.01) were less in TEA group. However, the incidence of hypotension (RR: 0.228; 95% CI: 0.137–0.380, p < 0.001), urinary retention (RR: 0.392; 95% CI: 0.198–0.776, p < 0.01), and vomiting (RR: 0.665; 95% CI: 0.451–0.981, p < 0.05) was less in PVB group. Conclusion For thoracotomy, PVB may provide no superior analgesia compared with TEA but PVB can reduce side effects. Thus, individualized treatment is recommended. Further study is still necessary to determine which concentration of local anesthetics can be used for PVB and can provide equal analgesic efficiency to TEA.


2007 ◽  
Vol 87 (4) ◽  
pp. 455-458 ◽  
Author(s):  
Martin T Moroni ◽  
Paul Q Carter ◽  
Dean W Strickland ◽  
Franz Makeschin ◽  
Don-Roger Parkinson ◽  
...  

Clearcutting Newfoundland boreal forests significantly reduced organic layer fungal and total microbial biomass in clearcut areas with and without slash cover, compared with forested plots. However, aerobically incubated respiration rates were highest in organic layers from clearcut areas under slash, intermediate under forests, and lowest from clearcut areas without slash. Key words: Carbon, ergosterol, fumigation–extraction, fungal biomass, harvest slash, nitrogen


2017 ◽  
pp. 120-122
Author(s):  
N.V. Avramenko ◽  
◽  
I.B. Gridina ◽  

Maintenance of reproductive health and decision of problem of safe contraception women with excessive weight have the issue of the day of present time and it is confessed by important direction of modern medicine. The objective: to define influence of hormonal contraception on the mucous membrane of neck of uterus for women with surplus mass of body. Patients and methods. In 90 women with excessive weight influence of hormonal contraception is studied on the mucous membrane of neck of uterus. Results. It is set that a modern hormonal contraception does not have a negative influence on the state of mucous membrane of neck of uterus for women with surplus mass of body. Conclusion. Women with excessive weight and can effectively and safely to use a modern hormonal contraception. But it is necessary to carry out a clinical supervision for the step of that additional elucidations are possible about the features of application of hormonal contraception for patients with excessive mass of body. Key words: contraception, overweight, side effects.


2017 ◽  
pp. 9-14
Author(s):  
L. Nazarenko ◽  

The article discusses the pathogenetic basis for the use of non-steroidal anti-inflammatory drugs (NSPVP) in obstetric practice for the treatment of pain syndrome in women with threatened abortion and pathological preliminary period. Provided with modern views on the mechanisms of analgesic clinical efficacy, side effects NSPVP. Provides information about the place of NSPVP during pregnancy, the risks to the fetus, the positive aspects in the conduct of women at risk of preterm birth, the pathological preliminary period. Key words: nonsteroidal anti-inflammatory drug, pain, premature birth, preliminary period.


2020 ◽  
pp. 72-77
Author(s):  
Ha Bui Manh ◽  
Thanh Le Thai Van

Aims: To evaluate the efficacy, side effects of laser 532-nm Nd:YAG picosecond in treating solar lentigo and ephelides at HCMC hospital of dermato-venereology. Objectives and Method: Prospective - descriptive study. There were 43 patients dealing with solar lentigo and ephelides treated with laser 532-nm Nd:YAG picosecond. Each patient went through 3 treatments with one month interval, three months follow up for delayed side effects and recurrent. Evaluating the treatment by MI, VLCS, self-patient evaluation with 5 grades scale. Evaluating side effects of the treatment by 5 grade Wong-Baker scale. Collected data were analysed with SPSS.20.0. Results: Based on MI at the end of the study, the effectiveness of the treatment gained 81.4% good, 16.3% average and 2.3% bad. Self-patient evaluation revealed 76.7% good, 20.9% average and 2.3% bad. VLCS of post-treatment reduced 7.44 ± 2.14 unit compares with of pre-treatment. Recently after treatment, 100% patients had erythema and mild pain in 5 grade Wong-Baker scale, 20.9% had mild edema, 2.3% had post imflammatory hyperpigmentation (PIH). Two ephelides cases recurred 3 months after treatment (4.6%). Conclusions: Laser 523-nm Nd:YAG picosecond has high efficacy and less side effects in treating solar lentigo and ephelides. Key words: solar lentigo, ephelides, laser 532-nm Nd:YAG picosecond


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