Efficacy of Acrylic Splint in Management of Internal Derangement of  Temperomandibular Joint

Occlusal splint plays a great role in the treatment of internal derangement of temporomandibular joint. Temporomandibular disorders affect 25 % of the population of the world. The purpose of the study was to elucidate the effectiveness of occlusal splint in reduction of pain, increase mouth opening, elimination of clicking sound. This randomized controlled clinical trial was done on 26 patients in two groups. Group A received occlusal splint and Group B received medications with supportive care. Monthly follow-up was done for a period of four months. In Group A and Group B, preoperative mean of mouth opening were 36.31 mm; and 39.77 mm. pain score 4.54 cm, clicking in 76.9% and 84.6% patients respectively. After 4 months of follow- up mouth opening 50.69 mm and 43.15 mm, pain score 0.154 cm and 0.69 cm, clicking 30.8% and 76.9% patients in both groups respectively. It may be conclude that the occlusal splint is highly efficient than medication and supportive care for managing of internal derangement of temporomandibular joint.

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Effectiveness of Pentoxifylline Therapy for Management of Oral Submucous Fibrosis

Journal of Nepalgunj Medical College ◽

10.3126/jngmc.v19i1.40228 ◽

2022 ◽

Vol 19 (1) ◽

pp. 51-54

Author(s):

Dwarika Prasad Bajgai ◽

Bela Agrawal ◽

Abadhesh Yadav

Keyword(s):

Oral Submucous Fibrosis ◽

Mouth Opening ◽

Burning Sensation ◽

Oral Disease ◽

Medical College ◽

Adjacent Structures ◽

Group A ◽

Submucous Fibrosis ◽

Group B

Introduction: Oral submucous fibrosis is a chronic oral disease characterized by progressive buildup of constricting collagen bands in the cheeks and adjacent structures of the mouth due to chewing of areca nut. This can severely restrict mouth opening and tongue movement causing pain and burning sensation in the mouth. Aims: This study evaluates the efficacy of pentoxifylline in the management of oral submucous fibrosis. Methods: A hospital-based study, conducted in the dental outpatient department of Nepalgunj Medical College from October 2019 to September 2020. Forty-nine patients who were diagnosed histopathologically with oral submucous fibrosis were included. The patients were divided into two groups. In group A, patients were given, 200 mg thrice daily for first 30 days, then dose hiked to 400 mg thrice daily for two more months. Group B patients received treatment with multi-vitamin capsules (B-complex one capsule before sleep daily) for three months. All patients were followed up for six months and were assessed for maximum inter-incisor opening, pain on opening of mouth and burning sensation. Results: There was no statistical difference in mouth opening at baseline and first follow up. The mouth opening was significantly more in group A compared to group B from second follow up which persisted till third follow up (p <0.05). Pain and burning sensation significantly reduced in group A compared to group B from 2nd follow up which persisted till 3rd follow up (p <0.05). Few patients had nausea, dyspepsia and vomiting during treatment in group A which resolved within a few days without the need for cessation of the drug. Conclusion: Pentoxifylline can bring about significant clinical improvements in the symptoms of oral submucous fibrosis like mouth opening, pain and burning sensation, thereby improving the quality of life of the affected individuals.

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THE EFFICACY OF HIGH CONDYLECTOMY IN INTERNAL DERANGMENT OF THE TEMPOROMANDIBULAR JOINT

International Journal of Medical and Biomedical Studies ◽

10.32553/ijmbs.v4i10.1457 ◽

2020 ◽

Vol 4 (10) ◽

Author(s):

Vikas Sarowa ◽

Vishnu Dayal Vyas ◽

D.K. Gupta ◽

Anjali Dave Tiwari

Keyword(s):

Temporomandibular Joint ◽

Small Sample Size ◽

Maxillofacial Surgery ◽

Mouth Opening ◽

Small Sample ◽

Internal Derangement ◽

Age Group ◽

Maxillofacial Region ◽

Anterior Disc Displacement

Background: Temporomandibular joint (TMJ) is a giglymoarthroidal Joint; it is the only mobile joint in the entire maxillofacial region and is a part of craniomandibular articulation. Methods: All the patients with internal derangement of temporomandibular joint having anterior disc displacement without reduction with complaints of pain and limited opening of mouth, of all age group reporting to the Department of Oral & Maxillofacial Surgery, GDC Jaipur were included in the study. Results: At one month follow up out of 20 patients 13 patients were not satisfied and at 6 month follow up 2 patients were not satisfied at all. Conclusion: We conclude that surgical treatment for internal derangement of the TMJ is required; this technique is effective to improve pain and mouth opening without complications. Although this study has a short follow up period and small sample size. Keywords: Mandible, Maxilla, TMJ.

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Efficacy and tolerability of 0.1% tazarotene cream and 0.05% tretinoin cream in the treatment of acne vulgaris

Bangabandhu Sheikh Mujib Medical University Journal ◽

10.3329/bsmmuj.v8i1.28916 ◽

2016 ◽

Vol 8 (1) ◽

pp. 24

Author(s):

Mohammad Habibur Rahman ◽

Md. Shahidullah Sikder ◽

Lubna Khondker

Keyword(s):

Treated Patient ◽

Acne Vulgaris ◽

Chronic Inflammatory Disease ◽

Controlled Clinical Trial ◽

Base Line ◽

Excellent Response ◽

Group A ◽

Group B ◽

Medical University

Background: Acne vulgaris is a chronic inflammatory disease of the pilosebaceous follicles that is seen primarily in adolescents.Objective: To compare the efficacy of 0.1 % tazarotene cream and 0.05% tretinoin cream in the treatment of mild to moderate acne vulgaris.Methods: A randomized controlled clinical trial was done in the department of Dermatology and Venereology, Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka, Bangladesh.Results: At base line mean number of comedones in group A and group B was 12.77 ± 4.01 and 11.80 ± 3.93 respectively (p=0.350) and at final follow up 4.17 ± 4.02 and 3.47 ± 4.00(p=0.501). At base line mean number ofpapules in group A and group B was 17.30 ± 10.29 and 18.57 ± 13.88 respectively (p=0.690) and at final follow up 7.63 ± 8.08 and 7.73 ± 9.98 (p=0.966). At base line mean number of pustules in group A and group B was 0.50 ± 1.33 and 0.53 ± 1.28 respectively (p=0. 922) and at final follow up 0.07 ± 0.37 and 0.00 (p=0.326). At baseline mean of total acne score was 30.57 ± 13.62 and 30.90 ± 17.17 in group A and B(p=0.934) and at final follow up it was 11.87 ± 12.04 and 11.20 ± 13.85 respectively in group A and B(p=0.846). At 1st follow up 3.3% of both group got excellent response, at 2nd follow up 13.3% of group A and 30.0% of group B got excellent response, and at final follow up 56.7% of group A and 63.3% of group B achieved excellent response. About 73.33% oftretinoin treated patient and 60% oftazarotene treated did not experience any side effects.Conclusion: It can be concluded that 0.1 % tazarotene cream and 0.05% tretinoin cream is individually effective and tolerability of 0.1 % tazarotene is comparable to 0.05% tretinoin in the treatment of mild to moderate acne vulgaris.

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Comparison of efficacy of needling and a combination of needling and platelet rich plasma in relieving pain and improving function in patients of tennis elbow: a prospective, randomized, double blinded, placebo controlled clinical trial

International Journal of Research in Orthopaedics ◽

10.18203/issn.2455-4510.intjresorthop20210617 ◽

2021 ◽

Vol 7 (2) ◽

pp. 258

Author(s):

Vikram Sharma ◽

Vivek Chandak

Keyword(s):

Tennis Elbow ◽

Platelet Rich Plasma ◽

Controlled Trial ◽

Lateral Epicondylitis ◽

Secondary Outcome ◽

Controlled Clinical Trial ◽

Group A ◽

Group B ◽

Double Blinded

Background: Lateral epicondylitis is a common musculoskeletal disorder for which an effective treatment strategy remains unknown. Aim of the study was to examine whether a single injection of platelet-rich plasma (PRP) with needling is more effective than needling with placebo in reducing pain in adults with lateral epicondylitis. Study design used was randomized controlled trial. Methods: A total of 66 patients with chronic lateral epicondylitis were randomized (1:1) to receive either a blinded injection of PRP (group A) or saline (placebo) group B. The primary end point was a change in pain using the VAS and patient-rated tennis elbow evaluation (PRTEE) questionnaire. The secondary outcome being improvement in function (PRTEE scores).Results: The VAS score and PRTEE score improved significantly in both the groups at all 3 follow-up examinations. Group A had significantly better results than the group B.Conclusions: PRP injection are safe and effective management strategy for lateral epicondylitis

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A Comparative Study Between Concentric Single-Needle Puncture Technique and Conventional 2-Needle Technique for Temporomandibular Joint Arthrocentesis Plus Corticosteroid Injections

Craniomaxillofacial Trauma & Reconstruction ◽

10.1177/1943387520911826 ◽

2020 ◽

Vol 13 (2) ◽

pp. 99-104

Author(s):

Amit Kumar ◽

Amit Gupta ◽

Rajarshi Ghosh ◽

Rajeev Pandey ◽

Sanjeev Kumar

Keyword(s):

Temporomandibular Joint ◽

Operating Time ◽

Mouth Opening ◽

Chief Complaint ◽

Needle Puncture ◽

Needle Technique ◽

Ringer’S Lactate ◽

Group A ◽

The Difference ◽

Group B

The purpose of the study was to compare 2 techniques of arthrocentesis, to find out the efficacy of one over the other at various parameters, and to contribute to the scarce literature of these 2 techniques. Forty patients reported with a chief complaint of pain in temporomandibular joint (TMJ), clicking in TMJ, and restricted mouth opening were included in this study. Twenty patients were divided into 2 groups, all reporting with temporomandibular disorders. Group A was treated with 2-needle technique of arthrocentesis, while group B underwent concentric needle technique of arthrocentesis under local anesthesia with Ringer’s lactate solution. The operating time was found to be less in concentric needle technique (mean: 25.36 minutes) compared to 2-needle technique (mean: 42.82 minutes), and the difference was found to be statistically significant. Concentric needle technique proved to be a better alternative for TMJ arthrocentesis as it has quite a lot of advantages over 2-needle technique.

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Platelet-Rich Plasma versus Corticosteroid Intra-Articular Injections for the Treatment of Trapeziometacarpal Arthritis: A Prospective Randomized Controlled Clinical Trial

Cartilage ◽

10.1177/1947603518805230 ◽

2018 ◽

Vol 12 (1) ◽

pp. 51-61 ◽

Cited By ~ 4

Author(s):

Michael-Alexander Malahias ◽

Leonidas Roumeliotis ◽

Vasileios S. Nikolaou ◽

Efstathios Chronopoulos ◽

Ioannis Sourlas ◽

...

Keyword(s):

Clinical Trial ◽

Platelet Rich Plasma ◽

Symptomatic Relief ◽

Controlled Clinical Trial ◽

Dash Score ◽

Ultrasound Guided ◽

Radiographic Osteoarthritis ◽

Group A ◽

Group B

Various systematic reviews have recently shown that intra-articular platelet-rich plasma (IA-PRP) can lead to symptomatic relief of knee osteoarthritis for up to 12 months. There exist limited data on its use in small joints, such as the trapeziometacarpal joint (TMJ) or carpometacarpal joint (CMCJ) of the thumb. A prospective, randomized, blind, controlled, clinical trial of 33 patients with clinical and radiographic osteoarthritis of the TMJ (grades: I-III according to the Eaton and Littler classification) was conducted. Group A patients (16 patients) received 2 ultrasound-guided IA-PRP injections, while group B patients (17 patients) received 2 ultrasound-guided intra-articular methylprednisolone and lidocaine injections at a 2-week interval. Patients were evaluated prior to and at 3 and 12 months after the second injection using the visual analogue scale (VAS) 100/100, shortened Disabilities of the Arm, Shoulder, and Hand Questionnaire (Q-DASH), and patient’s subjective satisfaction. No significant differences between the baseline clinical and demographic characteristics of the 2 groups were identified. After 12 months’ follow-up, the IA-PRP treatment has yielded significantly better results in comparison with the corticosteroids, in terms of VAS score ( P = 0.015), Q-DASH score ( P = 0.025), and patients’ satisfaction ( P = 0.002). Corticosteroids offer short-term relief of symptoms, but IA-PRP might achieve a lasting effect of up to 12 months in the treatment of early to moderate symptomatic TMJ arthritis.

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A CLINICAL STUDY ON MANAGEMENT OF POST-OPERATIVE PAIN AND QUALITY OF LIFE OF OSTEOARTHRITIS PATIENTS AFTER TOTAL KNEE ARTHROPLASTY

Asian Journal of Pharmaceutical and Clinical Research ◽

10.22159/ajpcr.2018.v11i4.23768 ◽

2018 ◽

Vol 11 (4) ◽

pp. 93

Author(s):

Tamilslevan T ◽

Kalaivani H

Keyword(s):

Quality Of Life ◽

Pain Score ◽

Post Operative Pain ◽

Group A ◽

Total Knee ◽

Inflammatory Drugs ◽

Group B ◽

Pain Symptoms

Objective: The objective of this study is to assess the effect of pregabalin in the management of post-operative pain and the quality of life (QOL) of osteoarthritis (OA) patients after total knee arthroplasty.Methods: This prospective observational study was conducted in the Department of Orthopedics. A total of 96 patients were divided into two groups. Group A consists of 50 patients with the treatment of nonsteroidal anti-inflammatory drugs (NSAIDs) and Group B consists of 46 patients with the treatment of pregabalin with NSAIDs. The study subjects were followed once in 60 days for 6 months, and they were asked to answer the visual analog scale (VAS) and knee injury and OA outcome score (KOOS) questionnaire. The effect of the treatment was assessed by comparing the baseline score with follow-up score.Results: Our study result showed that the pain score of Group B in VAS at 2nd follow-up was 2.56±0.34 and KOOS pain score was 92.73±3.45 (p<0.01). The QOL score was improved significantly to 81.56±5.29 (p<0.01) as compared to Group A.Conclusion: The study concluded that pregabalin with NSAIDs group patients showed a better improvement in pain, symptoms, and QOL within short duration as compared to NSAIDs alone used group.

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Comparison between stapler hemorrhoidectomy and open hemorrhoidectomy in the management of grade III and IV hemorrhoids: a prospective randomized study

International Surgery Journal ◽

10.18203/2349-2902.isj20181990 ◽

2018 ◽

Vol 5 (6) ◽

pp. 2069

Author(s):

Shailendra Pal Singh ◽

Somendra Pal Singh ◽

Vipin Gupta ◽

Kutubuddin Quadri ◽

Mohit Gupta

Keyword(s):

Pain Score ◽

Randomized Study ◽

Lithotomy Position ◽

Open Hemorrhoidectomy ◽

Early Results ◽

Group A ◽

The Difference ◽

Group B ◽

Grade Iii

Background: Haemorrhoids are one of the most common anorectal disorders. Haemorrhoids or piles are dilated veins of the anal canal and are more common in obesity, constipation and pregnancy. Classically they occur in the 3, 7 and 11 o'clock position with the patient in lithotomy position. Symptoms of haemorrhoids are per rectal bleeding and prolapse. Bleeding is bright red in colour and which is painless. The aim of the study was to compare the early results in 60 patients randomly allocated to undergo either stapled or open hemorrhoidectomy.Methods: Out of 60 patients, 30 (50.0%) patients underwent hemorrhoidectomy by Open Milligan-Morgan’s method were classified as Group A while rest 30 (50.0%) patients underwent hemorroidectomy by Stapler method after anal stretching, these patients were classified as Group B.Results: Pain score of majority of patients of Group A was ≥7 (76.7%), only 6.7% had pain score <3 and rest 16.7% had pain score 3 to 6. On comparing the difference of pain in passage of first stool among patients of Group A and Group B statistically was found to be highly significant. Pain in follow up at 3, 7 and 15th day was also significantly higher in group A in comparison to group B.Conclusions: Of the 60 patients in the current study, 32 are still in the follow up with the maximum follow up period of 11 months. There was no case of recurrence of haemorrhoids in this study. The factor of cost was not evaluated in the study since the hospital stay as well as stapling instrument was totally free in U.P, UMS, Saifai.

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A Comparative Study on Effectiveness of Rocabado Approach and Conventional Physiotherapy on Pain, ROM and QOL in Patients with TMJ Dysfunction

Journal of Pharmaceutical Research International ◽

10.9734/jpri/2021/v33i58b34192 ◽

2021 ◽

pp. 201-209

Author(s):

Sushma Pundkar ◽

Deepali Patil ◽

Waqar Naqvi

Keyword(s):

Comparative Study ◽

Temporomandibular Joint ◽

Mouth Opening ◽

Temporomandibular Joint Disorder ◽

Physiotherapy Treatment ◽

Joint Disorder ◽

Group A ◽

Conventional Physiotherapy ◽

Group B

Background: Temporomandibular joint disorder or dysfunction (TMD) are considered to be a subclass of the musculoskeletal disorders, so requires physiotherapy treatment. Till now very few studies have been done show the effectiveness of Rocabado approach and conventional physiotherapy, so the research aims to compare the effects of same in patients having mild to moderate Temporomandibular joint disorder. Methods: Subjects (n = 60) with TMJ dysfunction were selected for a comparative study. The participants were randomized into (1) Group A, and (2) Group B. Participants of Group A received Rocabado approach while Group B received the conventional physiotherapy along with home exercises for a period of 8 days immediately following baseline assessment. Discussion: The aim of the study was to compare the effectiveness of Rocabado approach and TENS in the patients having mild to moderate Temporomandibular joint disorder. To conclude, we can say that that the current study found evidence to justify the application of Rocabado’s technique to TMJ mobility. It helps patients with TMJ problems having mild to moderate dysfunction to improve their discomfort, mouth opening and quality of life.

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Evaluation of clinical parameters related to methotrexate therapy in lichen planus

Bangabandhu Sheikh Mujib Medical University Journal ◽

10.3329/bsmmuj.v6i2.29122 ◽

2016 ◽

Vol 6 (2) ◽

pp. 90

Author(s):

Samaresh Chandra Hazra ◽

Agha Masood Choudhury ◽

Lubna Khondker ◽

Md. Shirajul Islam Khan ◽

Muhammad Munir Rashid

Keyword(s):

Clinical Trial ◽

Lichen Planus ◽

Control Group ◽

Controlled Clinical Trial ◽

Clinical Parameters ◽

Morning Dose ◽

Group A ◽

Group B ◽

And Control

Background: For better management of lichen planus a clinical trial of oral methotrexate is necessary in ow· country. Objective: The objective of this study is to evaluate efficacy and safety ofmethotrexate therapy in the treatment of lichen planus.Methods: It was a prospective randomized controlled clinical trial conducted in the department of Dermatology and Venereology, BSMMU, Dhaka, from January 2009 to December 2010. Forty four patients of lichen planus were included in the study. Cases (group-A, n=23) were treated with methotrexate (10 mg) single morning dose and control (group-B, n=21) were treated with mini pulse betamethasone (5mg) single morning dose on 2 consecutive days during the period of 12 weeks. Results: Clinical parameters were measured by follow up clinical examination. Morphological lesion of lichen planus improved 95. 7% in group-A and only 28.6% improved in group-B. At the end of study 82.6% bad no complaints of itching in group-A and 100% had no complaints of itching in group-B. 16(69.6%) patients in group-A were completely cured clinically but 10(47.6%) in group-B. Anemia 3(14.2%) and edema 12(57.1 %) developed in group-B but none in group-A. In group-B, dyspepsia 15(71.4%), acne 10(47.6%),mooning face 8(38.1%), striae 8(38.1%) and hypertrichosis 4(19.0%) developed but none in group-A lntermittenr diarrhoea, headache, nausea and fatigue complained in both groups of patients but the percentage of complaints was higher amog group-8 compared to group-A. Menstrual abnormality developed in group-B 5(71.4%) but none in group-A.Conclusion: The overall adverse effects were less in group-A than group-B. Therefore, methotrexate can be used as an alternative safer option for the treatment of lichen planus.

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