scholarly journals Evaluation of the Knowledge and Perceptions about Pharmacovigilance Activities among Pharmacy Students in Nigeria: A Cross-Sectional Study

2017 ◽  
Vol 20 (1) ◽  
pp. 1-13
Author(s):  
Osemene Kanayo Patrick ◽  
Afolabi Margaret Olubunmi
Keyword(s):  
Age Groups ◽  
Knowledge Score ◽  
Cross Sectional Study ◽  
Pharmacy Students ◽  
Sectional Study ◽  
Knowledge Domain ◽  
Cross Sectional ◽  
Mean Values ◽  
Significant Difference ◽  
The Mean

Studies on pharmacovigilance (PV) activities in Nigeria focused on perceptions of PV among professional healthcare workers are described here. There is paucity of information on pharmacy students’ knowledge about PV activities. Hence, this study, evaluated the knowledge and perceptions of final year pharmacy students about PV activities using descriptive and inferential statistics. A cross sectional study was undertaken in three Nigerian universities with a pretested questionnaire during the period of January and February, 2016. The questionnaire included closed-ended questions on demographic variables and questions designed to achieve the objectives of the study. Data was analyzed with IBM SPSS Statistics 20 and presented in percentages, means, standard deviations and median at 50% percentile. The mean knowledge score of pharmacovigilance and adverse drug reporting for the final year students was 4.25±0.18. There were significant differences in the mean scores of knowledge domain by age groups 21-24 years 4.8±0.70, 25-30 years 6.2 ± 0.84 and >30 years 4.6±0.72 at p=0.001; gender: male 4.1±1.20 and female 4.4±0.98 at (p=0.0001) as well as the current universities attended as follows University 1 with a scrore of 5.1±1.03, University 2 had a mean score of 6.3±0.99 at p=0.0120 and University 3 with a mean score of 4.3±1.01 at p=0.012. Furthermore, significant difference exist in the mean values of pharmacovigilance knowledge between those who had taking some courses in pharmacovigilance (7.3± 0.22) and those who did not (4.7 ± 0.13) at p=0.0001. Generally, the students had inadequate knowledge of PV activities. Therefore, emphasis on relevant PV courses in their curriculum is necessary.Bangladesh Pharmaceutical Journal 20(1): 1-13, 2017

scholarly journals Genetic homozygosity as a marker of smoking dependency

Genetika ◽  
2020 ◽  
Vol 52 (3) ◽  
pp. 1009-1019
Author(s):  
Slavko Brankovic ◽  
Dejan Nikolic ◽  
Dragoslav Marinkovic ◽  
Suzana Cvjeticanin
Keyword(s):  
Cross Sectional Study ◽  
Male Gender ◽  
Sectional Study ◽  
Cross Sectional ◽  
Male And Female ◽  
Mean Values ◽  
Individual Variations ◽  
Significant Difference ◽  
The Mean ◽  
The Individual

The aim of our study was to evaluate the morphogenetic variability as a marker of smoking dependency in adult smokers versus controls and to investigate the presence and the degree of morphogenetic variability difference between male and female smokers versus same gender controls. The cross-sectional study evaluated 241 smokers and 185 nonsmoker individuals as controls. We analyzed 17 homozygous recessive characteristics (HRC). There was a significant difference in the individual variations of 17 HRCs between the controls and smokers (??2=61.400, p<0.001; for females ??2=79.440, p<0.001; for males ??2=84.972, p<0.001). The mean values of HRCs significantly differed between smokers and controls (MV?SEM(Controls) -4.79?0.13, MV?SEM(Smokers) -5.70?0.12; p<0.001). For males, presence of 6/17 (35.29% genetic homozygosity) HRCs (OR=6.12) was to the certain degree predictor for smoking dependency. Higher degree of genetic homozygosity, changed variability and male gender, might be some among potential numerous factors that could have impact on smoking development and dependence.

scholarly journals Evaluation of Anthropometric Indices and Biochemical Markers in Iranian Prediabetics in Hoveyzeh Located in Southwest Iran: A Cross-sectional Study

2021 ◽  
Vol In Press (In Press) ◽  
Author(s):  
Majed Meripour ◽  
Hashem Mohamadian ◽  
Morteza Abdullatif Khafaie
Keyword(s):  
Blood Pressure ◽  
Cross Sectional Study ◽  
Demographic Variables ◽  
Clinical Parameters ◽  
Sectional Study ◽  
Anthropometric Indices ◽  
Cross Sectional ◽  
Mean Values ◽  
Significant Difference ◽  
The Mean

Background: The number of prediabetic individuals is rising rapidly in Iran and other parts of the world. This complication seriously affects life quality and public health. Objectives: This study aimed to evaluate the anthropometric indices and biochemical measures among the prediabetic population. Methods: This cross-sectional study was conducted on prediabetic subjects in the Hoveyzeh population, Iran, during 2018 - 2019. A sample of 240 prediabetic individuals within the age range of 30-75 years enrolled in this study. The demographic characteristics, anthropometric measurements, and participants’ clinical parameters were checked out in this study. Moreover, this study investigated important demographic variables associated with anthropometric and clinical parameters. Results: The results showed that the mean values of fasting plasma glucose, triglyceride, and total cholesterol were 113.13 ± 6.8, 193.64 ± 115.44, and 193.64 ± 40.67 mg/dl, respectively. The mean values of systolic blood pressure and diastolic blood pressure (DBP) were 114.75 ± 15.25 and 73.25 ± 8.81 mmHg, respectively. The results showed no statistically significant difference between clinical and demographic variables except between DBP and marital status (P < 0.05). The prevalence of prediabetes in Hoveyzeh was closely associated with some demographic, anthropometric, and clinical variables. This study documented significant associations between height, hip circumference, and body mass index with both genders (P < 0.05). Furthermore, there was no statistical relationship between other demographic and anthropometric variables (P > 0.05). Conclusions: Based on the findings, abdominal obesity indicators may be related to prediabetes. Therefore, preventive strategies and suitable educational programs should be based on influential factors.

scholarly journals Relationship between age, refractive errors and motor fusion in a normal Chinese adult population: a cross-sectional study

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Man She ◽  
Tao Li ◽  
Qianqian Hu ◽  
Jie Zhu ◽  
Xiaodong Zhou
Keyword(s):  
Adult Population ◽  
Linear Regression Analysis ◽  
Age Groups ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Comfort Zone ◽  
Cross Sectional ◽  
Mean Values ◽  
Chinese Adult ◽  
The Mean

Abstract Background To investigate the relationships between motor fusion and sex, age and spherical equivalent (SE). Methods This observational study enrolled 243 healthy, nonstrabismic adults, including 94 men and 149 women aged 20 to 59 years. The subjects were divided into three groups according to SE: myopic, emmetropic and hyperopic groups. The subjects were also divided into four groups according to age: 20–29, 30–39, 40–49 and 50–59 years groups. Motor fusion was measured with a synoptophore, including subjective angle (SA), divergence, convergence and fusional vergence range (FVR). Results The mean values of divergence, convergence and FVR for the whole sample group were 9.72 ± 0.26°, 19.34 ± 0.54°, and 29.06 ± 0.62°, respectively. A higher value of divergence was found in the myopic group than in the emmetropic group (p < 0.05). SE and divergence were significantly different among age groups (all p < 0.05). In addition, linear regression analysis showed that SE was correlated with divergence (p = 0.003). Age was correlated with SE, divergence and FVR (p < 0.001, p = 0.005, p = 0.002, respectively). In addition, the proportion of SA being in the comfort zone (defined as the value of SA satisfying Percival’s criterion) in the age groups was significantly different (χ2 = 8.283, p = 0.041). Conclusions Motor fusion is associated with age and SE in the normal Chinese adult population.

scholarly journals DERMAL PAPILLAE;

2019 ◽  
Vol 26 (02) ◽  
Author(s):  
Ayesha Baqar
Keyword(s):  
Age Groups ◽  
Cross Sectional Study ◽  
P Value ◽  
Sectional Study ◽  
Cross Sectional ◽  
Significant Difference ◽  
Group A ◽  
The Mean ◽  
Group B ◽  
Dermal Papillae

Introduction: To study and compare the changes in the height of dermal papillae in the skin of different age groups in a segment of Pakistani population. Study Design: Cross sectional study. Period: Five months, from July 2010 to November 2010. Setting: Anatomy Department, Army Medical College, Rawalpindi. Materials & Method: Sixty volunteers of both sexes, after fulfilling the inclusion criteria, participated in this cross sectional study. They all gave written informed consent. They were divided into three equal groups according to their ages, Group A ranged in age from 18 – 29 years, Group B from 30 – 49 years, and Group C > 50 years. Punch biopsies were taken from the sun protected upper arm skin, from all volunteers, after giving local anaesthesia. Samples were stained with Hematoxylin and Eosin. They were observed under light microscope. Height of dermal papillae was measured at three random sites in each sample and mean was taken.The mean of all three groups was compared with each other and data was analyzed. Results: The mean of each sample was taken and then final mean of each group was calculated. They were then compared with each other. The mean height of dermal papillae of group A was 98.667µm, that of group B was 83.333µm and the mean height of dermal papillae in group C was 47.33µm. There was significant difference between the three groups and ‘p’-value was less than 0.5. Conclusion: At the end of this study, it was concluded that, the height of dermal papillae reduces significantly with age.

scholarly journals A Sonographic Study of Kidney Dimensions Among Nepalese Children

2020 ◽  
Vol 40 (3) ◽  
pp. 164-171
Author(s):  
Dil Islam Mansur ◽  
Subindra Karki ◽  
Pragya Shrestha ◽  
Sunima Maskey
Keyword(s):  
Normal Values ◽  
Age Groups ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional ◽  
Mean Values ◽  
The Mean ◽  
Nepalese Children ◽  
Kidney Dimensions ◽  
Renal Length

Introduction: Any variations in shape or size of either one or both kidneys may indicate sign of its pathology. The study was aimed to determine normal values for renal dimensions among Nepalese children. Methods: This was a cross-sectional study of the renal dimensions among 211 children. The length, breadth and thickness of kidneys were measured by computerised in built calliper in centimetre by using ultrasound and volume of the kidney was calculated. Results: The mean values of length, breadth, thickness and volume were 7.05 ± 1.80 cm, 2.95 ± 0.48 cm, 1.35 ± 0.15 cm and 15.09 ± 5.91 cc for right kidneys respectively; and 7.36 ± 1.89 cm, 2.98 ± 1.89 cm, 1.35 ± 0.18 cm and 15.98 ± 6.44 cc for left kidneys respectively. The mean values for length, breadth, thickness and volume of right kidney was 7.57 ± 1.99 cm, 3.11 ± 0.46 cm, 1.38 ± 0.14 cm and 17.38 ± 6.20 cc among boys respectively; and 6.50 ± 1.39 cm, 2.78 ± 0.44 cm, 1.31 ± 0.17 cm and 12.69 ± 4.43 cc among girls respectively. Similarly, these values for length, breadth, thickness and volume of left kidneys were 7.91 ± 2.04 cm, 3.13 ± 0.49 cm, 1.39 ± 0.18 cm and 18.46 ± 6.89 cc among boys respectively; and 6.78 ± 1.52 cm, 2.83 ± 0.45 cm, 1.31 ± 0.17 cm and 13.38 ± 4.73 cc among girls respectively. Conclusions: It was concluded that mean values for renal length and volume was found to be higher on left side than right side in all age groups. These values for renal breadth and thickness were observed almost same on both sides in all age groups. All measurements of renal dimensions were found significantly higher among boys than girls on both sides. This study has provided the reference values for renal sizes among Nepalese children.

Effect of Medialization of the Trochlear Groove and Lateralization of the Tibial Tubercle on TT-TG Distance: A Cross-sectional Study of Dysplastic and Nondysplastic Knees

2021 ◽  
pp. 036354652098781
Author(s):  
Mathias Paiva ◽  
Lars Blønd ◽  
Per Hölmich ◽  
Kristoffer Weisskirchner Barfod
Keyword(s):  
Trochlear Dysplasia ◽  
Cross Sectional Study ◽  
Magnetic Resonance Images ◽  
Tibial Tubercle ◽  
Control Group ◽  
Trochlear Groove ◽  
Sectional Study ◽  
Cross Sectional ◽  
Mean Values ◽  
The Mean

Background: Tibial tubercle–trochlear groove (TT-TG) distance is often used as a measure of lateralization of the TT and is important for surgical planning. Purpose: To investigate if increased TT-TG distance measured on axial magnetic resonance images is due to lateralization of the TT or medialization of the TG. Study Design: Cross-sectional study; Level of evidence, 3. Methods: A total of 84 knees (28 normal [NK], 28 with trochlear dysplasia [TD], and 28 with patellar dislocation without TD [PD]) were examined. The medial border of the posterior cruciate ligament (PCL) was chosen as the central anatomic landmark. The distance from the TT to PCL (TT-PCL) was measured to examine the lateralization of the TT. The distance from the TG to the PCL (TG-PCL) was measured to examine the medialization of the TG. Between-group differences were investigated by use of 1-way analysis of variance. Results: The mean values for TT-TG distance were 8.7 ± 3.6 mm for NK, 12.1 ± 6.0 mm for PD, and 16.7 ± 4.3 mm in the TD group ( P < .01). The mean values for TT-PCL distance were 18.5 ± 3.6 mm for NK, 18.5 ± 4.5 mm for PD, and 21.2 ± 4.2 mm in the TD group ( P = .03). The mean values for TG-PCL distance were 9.6 ± 3.0 mm for NK, 7.1 ± 3.4 mm for PD, and 5.1 ± 3.3 mm in the dysplastic group ( P < .01). Conclusion: The present results indicate that increased TT-TG distance is due to medialization of the TG and not lateralization of the TT. Knees with TD had increased TT-TG distance compared with the knees of the control group and the knees with PD. The TT-PCL distance did not differ significantly between groups, whereas the TG-PCL distance declined with increased TT-TG.

scholarly journals Superior versus Inferior Conjunctival Limbal Autograft with Sutures in the Management of Primary Pterygium in a Tertiary Care Hospital in Dakshina Kannada - A Cross Sectional Study

2021 ◽  
Vol 8 (11) ◽  
pp. 603-607
Author(s):  
Madhuri Upadhyaya ◽  
Sheetal Savur
Keyword(s):  
Cross Sectional Study ◽  
Bulbar Conjunctiva ◽  
Care Hospital ◽  
Sectional Study ◽  
Surgical Time ◽  
Cross Sectional ◽  
Significant Difference ◽  
The Mean ◽  
Pterygium Excision ◽  
Primary Pterygium

BACKGROUND Pterygium excision with conjunctival limbal autograft (CAU) is one of the most frequently used modalities in the treatment of pterygium. The graft has traditionally been harvested from the superior bulbar conjunctiva, but this may not be possible in all patients. The purpose of this study was to compare the intraoperative difficulties and early postoperative outcomes between superior and inferior CAU in the management of primary pterygium. METHODS This hospital based cross sectional study evaluated 58 eyes of 50 patients with primary pterygium who underwent pterygium excision with conjunctival limbal autograft secured with the help of sutures over a period of 2 years from March 2018 to March 2020. In 28 eyes, the superior bulbar conjunctiva was used for grafting whereas in 30 eyes, the inferior conjunctiva was used for the same. The outcome measured was in terms of the mean surgical time, clinical symptoms and signs in the early postoperative period and recurrence rate. RESULTS The mean age of the patients was 44.14 ± 12.71 years in the superior CAU group and 45.76 ± 14.51 years in the inferior CAU group. There was no statistically significant difference between the two groups in terms of the mean surgical time (68.39 ± 31.51 in superior group, 2.60 ± 0.79 in inferior group; P value 0.712). The duration of follow-up after surgery was significantly more (P = 0.048) in the inferior CAU group (42.60 ± 11.71 days) as compared to the superior CAU group (37.39 ± 7.52 days). Postoperative symptoms were comparable, and no recurrence was observed in either of the two groups. CONCLUSIONS Pterygium excision with inferior conjunctival limbal autograft is safe and effective in the management of primary pterygia and may be considered as an alternative to superior graft in cases where harvesting the superior conjunctiva is not possible or not advisable. KEYWORDS Primary Pterygium, Conjunctival Limbal Autograft, Inferior Graft

A study of growth changes in the mandible from deciduous to permanent dentition

2004 ◽  
Vol 27 (2) ◽  
pp. 137-142 ◽  
Author(s):  
Hung-Huey Tsai
Keyword(s):  
Cross Sectional Study ◽  
Permanent Dentition ◽  
Developmental Changes ◽  
Sectional Study ◽  
Cross Sectional ◽  
Mean Values ◽  
Males And Females ◽  
The Mean ◽  
Growth Changes ◽  
Ramus Height

This cross-sectional study investigated mandibular developmental changes in untreated normal Taiwanese from the deciduous to permanent dentition. Differences in the mean values for ramus height and body length between males and females were statistically significant after eruption of the permanent second molars. SNB angles significantly increased and gonial and L1-MP angles significantly decreased from deciduous to permanent dentition in both sexes. The SN-MP angle in females significantly decreased and ramus inclination in males significantly increased from the early mixed to permanent dentition.

scholarly journals Orthodontic Treatment Knowledge among General Dentists and Non-orthodontic Specialists

2019 ◽  
Vol 9 (1) ◽  
pp. 40-44
Author(s):  
Asal Acharya ◽  
Praveen Mishra ◽  
Rabindra Man Shrestha ◽  
Pooja Shah
Keyword(s):  
Orthodontic Treatment ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Multiple Choice Questions ◽  
Cross Sectional ◽  
Significant Difference ◽  
Treatment Knowledge ◽  
Treatment Concepts ◽  
The Mean ◽  
General Dentists

Introduction: General dentists and specialists other than orthodontist may encounter patient requiring orthodontic treatment. For proper counseling and referral, it is important that general dentists and non-orthodontic specialists have adequate level of orthodontic knowledge. Objective: To assess the knowledge of orthodontic treatment among general dentists and non-orthodontic specialists and to compare the knowledge between the two groups. Materials & Method: A descriptive cross sectional study using questionnaire was performed among 185 actively practicing general dentists and non-orthodontic specialists of Nepal. The questionnaire comprised of three parts. The first part included demographic details, second part contained 5 multiple choice questions regarding orthodontic counseling and third part integrated 18 questions for evaluating knowledge of orthodontic treatment. Each correct answer was given score 1 and every incorrect answer was scored zero in the third part of the questionnaire. Result: Among total participants, 60.5% think first orthodontic evaluation of a child should be carried out within 7 to 8 years of age and 44.3% think orthodontic treatment can even be started after 40 years of age. Around 66% of the participants think that orthodontic treatment cannot be performed in periodontally compromised cases. No significant difference was found between the mean scores of knowledge among general dentists and non-orthodontic specialists (p=0.891), or among dentists with different years of experience (p=0.644). Conclusion: There is a need for more education of orthodontic treatment concepts to the dentists who do not belong to orthodontic field for proper counseling and referral.

scholarly journals Comparing the Lifestyle of Veteran and Non-Veteran Families in Tehran

2020 ◽  
Author(s):  
Seyed Alireza Afshani ◽  
Seyed Mostajad Hosseini-motlagh
Keyword(s):  
Health Literacy ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Community Members ◽  
Cross Sectional ◽  
Statistical Population ◽  
Significant Difference ◽  
Lifestyle Questionnaire ◽  
The Mean ◽  
Descriptive Level

Introduction: Lifestyle of a community members  should be investiagted, especially in the devotees and their families. The present research aimed at measuring and comparing the lifestyle status of veteran and non-veteran families in Iran. Methods: In this cross-sectional study, the statistical population included the veteran and non-veteran families in Tehran City and the sample size included 360 people. The research instruments were Lali, Abedi, and Kajbaf’s Lifestyle Questionnaire (LSQ) (2012), and All Aspects of Health Literacy Scale (AAHLS, 2013). The data were analyzed by SPSS v.24. At the descriptive level, graphing was performed and at the inferential level, Pearson, t-test, Friedman, and analysis of variance tests were run. Results: A significant difference was observed between the mean scores of lifestyle in two groups of Veteran and Non-Veteran in Tehran. No significant difference was found between the lifestyle scores of men and women in the Non-Veteran group as well as between the mean scores of the single and married lifestyle in the Veteran and Non-Veteran group (P<0/05). However, a significant relationship was found between health literacy and lifestyle of the veteran and non-veteran participants (p<0/05). Conclusion: The results showed that lifestyle should be considerd as a set of observable behaviors and health literacy should be investiagted as predicting variables in promoting lifestyle in the Veteran and Non-Veteran groups.

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