scholarly journals Effect of Combined Oral Contraceptive Pill on FVC, FEV1 and FEV1/FVC%

2015 ◽  
Vol 10 (1) ◽  
pp. 21-25
Author(s):  
Farhana Islam ◽  
Nasim Jahan ◽  
Nayma Sultana

Background: Combined oral contraceptive pill (COCP) is the most commonly used contraceptive method in Bangladesh. This COCP may have some effects on different organs including lungs.Objective: To observe the effects of combined oral contraceptive pill (COCP) on FVC, FEV1 and FEV1/ FVC% in apparently healthy women receiving COCP.Methods: This cross sectional study was carried out in the Department of Physiology, Sir Salimullah Medical College (SSMC), Dhaka between July 2013 and June 2014. A total 30 apparently healthy young women, age ranged 20 to 30 years were included in this study who were combined oral contraceptive pill users (COCP-U) for at least 6 months. Thirty age and BMI matched combined oral contraceptive pill nonusers (COCP-NU) were taken as control. FVC, FEV1 and FEV1/FVC% of all the subjects were measured by digital spirometer. Statistical analysis was done by Independent sample ‘t’ test.Results: FVC (p<0.001), FEV1 (p<0.001) were significantly higher whereas, FEV1/FVC% (p<0.05) was significantly lower in COCP-U than those of COCP-NU. Moreover, the mean serum estrogen (p<0.001) and progesterone (p<0.05) levels were also significantly higher in COCP-U in comparison to those of COCP-NU.Conclusion: From the result of this study it can be concluded that COCP have beneficial effects on some pulmonary function parameters.Bangladesh Soc Physiol. 2015, June; 10(1): 21-25

2017 ◽  
Vol 26 (Number 1) ◽  
pp. 21-26
Author(s):  
Samsunnahar ◽  
Q S Akhter ◽  
N Akhter ◽  
K Sultana ◽  
Md. Atiquzzaman ◽  
...  

This study was done to assess the hypercoagulability and the risk of thromboembolism in women taking oral contraceptive pill for prolonged period of time. This cross sectional study was done in the department of Physiology, Dhaka Medical College, Dhaka from Jan 2012 to Dec 2012. Ninety female subjects with the age range from 25-45 years, were taken as a study population. Among them, 60 women taking oral contraceptives for prolonged period of time ( > 1 years) were included for the study group and age matched 30 women of OCP nonusers were taken as a control. Study subjects were divided into two groups according to their duration of oral pill use: group BI ( 1 to 5 years users) were 30 women and group B2 ( >5 to 10 years users) were 30 women. Prothrombin time and activated partial thromboplastin time were estimated in all groups. Statistical analysis was done by unpaired Student's ? t' test and Pearson's Correlation Coefficient test. In this study, the mean (*SD) PT levels in group B1 & B2 were shortened than that of group A which were statistically highly significant (P < 0.001). Within the study groups, PT levels were positively correlated (r=+0.027) with the group B1 and negatively correlated (r= -0.163) with the group B2. But both the relationships were statistically non significant. The mean (+SD) AM' level in group B1 was shortened than that of group A but the result was not statistically significant. The mean (*SD) AM' level in group B2 was shortened than that of group A but the result was statistically highly significant (P<0.001). Within the study groups, APPT levels were negatively correlated with the group B1 (r= -0.268) and also group B2 (r= -0.122). But both the relationships were statistically non significant. My present study revealed that prolonged duration of OCP use ( at least for 5 years) increases the risk of hypercoagulable state and thromboembolism in women.


2016 ◽  
Vol 11 (1) ◽  
pp. 35-38
Author(s):  
Md Abul Hasanat ◽  
Chandra Rani Sarkar ◽  
ATM Zoadur Rahim Zahid

Background: Workers in environment with cotton dust exposure are at risk of development of occupational pulmonary functional disorder.Objectives: To observe the effects of cotton dust exposure on FVC, FEV1, FEV1/FVC% in male cotton dust worker.Methods: This cross-sectional study was carried out in the department of physiology, Rangpur Medical College, Rangpur from 2014’july to 2015’July. Total 25 apparently healthy non-smoker male workers aged 20-40 years, exposed to cotton dust for at least 6 months, were selected from different fabric weaving and cotton ginning factories of Rangpur district. Twenty five age & BMI matched apparently healthy male subjects, not exposed to cotton dusts were taken as control. FVC, FEV1 and FEV1 /FVC% of all subjects were recorded by using a digital spirometer. For statistical analysis, unpaired‘t’-test was performed.Results: The mean percentage of predicted value of FVC, FEV1 were significantly lower (p<0.001) in cotton dust exposed workers (CD-EW) than those of control. The mean percentage of predicted value of FEV1 / FVC% in CD-EW is slightly decreased compared to control but it was not statistically significant.Conclusions: From the result of this study it can be concluded that cotton dust (CD) may have harmful effects on some pulmonary function.Bangladesh Soc Physiol. 2016, June; 11(1): 35-38


2019 ◽  
Vol 9 (6-s) ◽  
pp. 53-57
Author(s):  
Zeinab Atif Ahmed Osman ◽  
Sara Elsadig Babiker ◽  
Nihad Elsadig Babiker

Contraceptives are intentional prevention of conception through the use of various devices sexual practices, chemicals, drugs or surgical procedures become a contraceptive if its purpose is to prevent a woman from becoming pregnant. This is a cross sectional study conducted at ALnow Hospital Khartoum, Sudan,  the study aimed to estimate D.dimer levels among Sudanese women take contraceptive pill.    50 Women uses contraceptive pill used as a cases and 50 apparently health women were used as a control. Three   ml of venous blood samples were collected from each subject in 3.8% tri-sodium citrate (9:1 vol/vol) for D-dimer analysis.  The study revealed that was clearly significant increase in D.dimer in women take oral contraceptive pill (p.value 0.000), also the study concluded that D-dimer level was increased in users oral contraceptive Sudanese women,  that is increase the coagubility of the blood  and might be become as a risk factor.   Keywords: Contraceptive pills, D.dimer, coagubility.


Author(s):  
Yuniarty Amra ◽  
Joseph L Tumeida ◽  
Edi Hartono

Objectives: The aim of this research was to assess the relationship between total testosterone level and female sexual function based on Female Sexual Function Index (FSFI) among the acceptors of combined oral contraceptive pill. Methods: The research was conducted in BLU of Dr. Wahidin Sudirohusodo Hospital and several teaching hospitals in obstetrics and gynecology sections of Medical faculty, Hasanuddin University from October to December 2012. This study assessed sexual function among 60 women as the acceptors of combined oral contraceptive pill. Sexual function was assessed using FSFI questionnaire which had been validated in several countries. This research used cross sectional design and the sample was selected using consecutive sampling method. The data were processed using SPSS with independent t test of the significant level of 0.05. Results: The results of the research reveal that total testosterone level among the acceptors of combined oral contraceptive pill who have impaired sexual function is low. The result of the correlation test between testosterone level and FSFI score indicates a significant level (p<0.05) with a correlation coefficient of (r) = 0.737. The testosterone level of female who have impaired sexual function is significantly different (p<0.05) from women who have normal sexual function. The cut off testosterone level that could indicate the occurrence of sexual dysfunction is 12.4 ng/dl. Conclusion: The total testosterone level among the acceptors of combined oral contraceptive pill who have impaired sexual function is lower than others who have no impaired sexual function. [Indones J Obstet Gynecol 2013; 1-3: 129-33] Keywords: combined oral contraceptive pill, FSFI, sexual function, total testosterone level


2014 ◽  
Vol 26 (1-2) ◽  
pp. 25-29 ◽  
Author(s):  
Tahmina Yeasmin ◽  
Md. Shahidul Haque ◽  
Shahanara Yeasmin ◽  
Md. Ruhul Amin

Objectives: To assess the iron status of women using oral contraceptive pill (OCP) and compare this status with that of women of non-OCP users. Methods: This prospective cross-sectional comparative study was done in Dhaka Medical College from January 2006 to December 2006. Total 61 apparently healthy women of low socioeconomic class, age ranged 20-40 years were selected from different areas of Dhaka city. Of them 41 women were OCP users (Study group) and 20 women were non-OCP users (for comparison). OCP users again subdivided into subgroups according to duration of OCP use. Serum ferritin and haemoglobin level were taken as parameters of iron status in both groups. Statistical analysis was done by the SPSS 12.0 programme. Results: The mean (±SD) of serum ferritin level were 59.45±24.79ng/ml and 77.36±35.16 ng/ml in non-OCP & OCP users respectively. The difference of mean (±SD) of serum ferritin levels were significant (p:<0.05) between two groups. The mean (±SD) of haemoglobin levels were 11.54±0.76gm/dl and 12.04±0.79gm/dl in non-OCP user and OCP users respectively. The difference of mean (±SD) were significant (p:<0.05) between two groups. Levels of serum ferritin & haemoglobin were 19ng/ml and 10.95gm/dl respectively in women using OCP for 1 year. But their levels became 144 ng/ml and 13.95gm/dl respectively in women using OCP for 12 years. Conclusion: This study suggests that OCP use raises serum ferritin and haemoglobin levels and thus has beneficial effects on iron status of the body. http://dx.doi.org/10.3329/bjpp.v26i1-2.19963 Bangladesh J Physiol Pharmacol 2010; 26(1&2) : 25-29


2020 ◽  
Vol 22 (3) ◽  
pp. 141-145
Author(s):  
Krishna Chandra Devkota ◽  
S Hamal ◽  
PP Panta

Pleural effusion is present when there is >15ml of fluid is accumulated in the pleural space. It can be divided into two types; exudative and transudative pleural effusion. Tuberculosis and parapneumonic effusion are the common cause of exudative pleural effusion whereas heart failure accounts for most of the cases of transudative pleural effusion. This study was a hospital based cross sectional study performed at Nepal Medical College during the period of January 2016-December 2016. A total of 50 patients who fulfilled the inclusion criteria were enrolled. Pleural effusion was confirmed by clinical examination and radiology. After confirmation of pleural effusion, pleural fluid was aspirated and was analysed for protein, LDH, cholesterol. The Heffner criteria was compared with Light criteria to classify exudative or transudative pleural effusion. Among 50 patients, 30 were male and 20 were female. The mean age of patient was 45.4±21.85 years. The sensitivity and specificity of using Light criteria to detect the two type of pleural effusion was 100% and 90.9%, whereas using Heffner criteria was 94.87%, 100% respectively(P<0.01). There are variety of causes for development of pleural effusion and no one criteria is definite to differentiate between exudative or transudative effusion. In this study Light criteria was more sensitive whereas Heffner criteria was more specific to classify exudative pleural effusion. Hence a combination of criteria might be useful in case where there is difficulty to identify the cause of pleural effusion.


2021 ◽  
Vol 15 (12) ◽  
pp. 3198-3199
Author(s):  
Pervez Muhammad ◽  
Sajjad Muhammad ◽  
Muhammad Tariq ◽  
Amir Khan ◽  
Akhtar Munir ◽  
...  

Aim: Prevalence of colorectal carcinoma with respect to age and gender Study design: Observational / cross sectional study. Place and duration of study: This study was conducted at the Department of Pathology and Surgery, Post Graduate Medical Institute Lahore and Jinnah Medical College Peshawar from July, 2013 to February, 2015 Methodology: Surgical specimens of 60 histopathologically diagnosed cases of colorectal adenocarcinoma were included in this study. Age and sex were evaluated in CRC. Results: The mean±sd of age was 54.4±19.7 yrs. Out of 60 cases, 6 (10%) were between 16-29 yrs, 9 (15%) cases were between 30-49 yrs, 34 cases (56.7%) were of 50-69 yrs and 11 cases (18.33%) were of 70 yrs. Out of sixty cases, males were 33 (55%) and females were 27(45%). Conclusion: There are 34 out of 60(56.7%) patients were 50-69 years and 33 out of 60 (55%) cases were males i.e. males dominance. Keywords: Colorectal adenocarcinoma, immunohistochemistry, gender


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