scholarly journals Iron status in women using oral contraceptives

2014 ◽  
Vol 26 (1-2) ◽  
pp. 25-29 ◽  
Author(s):  
Tahmina Yeasmin ◽  
Md. Shahidul Haque ◽  
Shahanara Yeasmin ◽  
Md. Ruhul Amin

Objectives: To assess the iron status of women using oral contraceptive pill (OCP) and compare this status with that of women of non-OCP users. Methods: This prospective cross-sectional comparative study was done in Dhaka Medical College from January 2006 to December 2006. Total 61 apparently healthy women of low socioeconomic class, age ranged 20-40 years were selected from different areas of Dhaka city. Of them 41 women were OCP users (Study group) and 20 women were non-OCP users (for comparison). OCP users again subdivided into subgroups according to duration of OCP use. Serum ferritin and haemoglobin level were taken as parameters of iron status in both groups. Statistical analysis was done by the SPSS 12.0 programme. Results: The mean (±SD) of serum ferritin level were 59.45±24.79ng/ml and 77.36±35.16 ng/ml in non-OCP & OCP users respectively. The difference of mean (±SD) of serum ferritin levels were significant (p:<0.05) between two groups. The mean (±SD) of haemoglobin levels were 11.54±0.76gm/dl and 12.04±0.79gm/dl in non-OCP user and OCP users respectively. The difference of mean (±SD) were significant (p:<0.05) between two groups. Levels of serum ferritin & haemoglobin were 19ng/ml and 10.95gm/dl respectively in women using OCP for 1 year. But their levels became 144 ng/ml and 13.95gm/dl respectively in women using OCP for 12 years. Conclusion: This study suggests that OCP use raises serum ferritin and haemoglobin levels and thus has beneficial effects on iron status of the body. http://dx.doi.org/10.3329/bjpp.v26i1-2.19963 Bangladesh J Physiol Pharmacol 2010; 26(1&2) : 25-29

2015 ◽  
Vol 10 (1) ◽  
pp. 21-25
Author(s):  
Farhana Islam ◽  
Nasim Jahan ◽  
Nayma Sultana

Background: Combined oral contraceptive pill (COCP) is the most commonly used contraceptive method in Bangladesh. This COCP may have some effects on different organs including lungs.Objective: To observe the effects of combined oral contraceptive pill (COCP) on FVC, FEV1 and FEV1/ FVC% in apparently healthy women receiving COCP.Methods: This cross sectional study was carried out in the Department of Physiology, Sir Salimullah Medical College (SSMC), Dhaka between July 2013 and June 2014. A total 30 apparently healthy young women, age ranged 20 to 30 years were included in this study who were combined oral contraceptive pill users (COCP-U) for at least 6 months. Thirty age and BMI matched combined oral contraceptive pill nonusers (COCP-NU) were taken as control. FVC, FEV1 and FEV1/FVC% of all the subjects were measured by digital spirometer. Statistical analysis was done by Independent sample ‘t’ test.Results: FVC (p<0.001), FEV1 (p<0.001) were significantly higher whereas, FEV1/FVC% (p<0.05) was significantly lower in COCP-U than those of COCP-NU. Moreover, the mean serum estrogen (p<0.001) and progesterone (p<0.05) levels were also significantly higher in COCP-U in comparison to those of COCP-NU.Conclusion: From the result of this study it can be concluded that COCP have beneficial effects on some pulmonary function parameters.Bangladesh Soc Physiol. 2015, June; 10(1): 21-25


2017 ◽  
Vol 26 (Number 1) ◽  
pp. 21-26
Author(s):  
Samsunnahar ◽  
Q S Akhter ◽  
N Akhter ◽  
K Sultana ◽  
Md. Atiquzzaman ◽  
...  

This study was done to assess the hypercoagulability and the risk of thromboembolism in women taking oral contraceptive pill for prolonged period of time. This cross sectional study was done in the department of Physiology, Dhaka Medical College, Dhaka from Jan 2012 to Dec 2012. Ninety female subjects with the age range from 25-45 years, were taken as a study population. Among them, 60 women taking oral contraceptives for prolonged period of time ( > 1 years) were included for the study group and age matched 30 women of OCP nonusers were taken as a control. Study subjects were divided into two groups according to their duration of oral pill use: group BI ( 1 to 5 years users) were 30 women and group B2 ( >5 to 10 years users) were 30 women. Prothrombin time and activated partial thromboplastin time were estimated in all groups. Statistical analysis was done by unpaired Student's ? t' test and Pearson's Correlation Coefficient test. In this study, the mean (*SD) PT levels in group B1 & B2 were shortened than that of group A which were statistically highly significant (P < 0.001). Within the study groups, PT levels were positively correlated (r=+0.027) with the group B1 and negatively correlated (r= -0.163) with the group B2. But both the relationships were statistically non significant. The mean (+SD) AM' level in group B1 was shortened than that of group A but the result was not statistically significant. The mean (*SD) AM' level in group B2 was shortened than that of group A but the result was statistically highly significant (P<0.001). Within the study groups, APPT levels were negatively correlated with the group B1 (r= -0.268) and also group B2 (r= -0.122). But both the relationships were statistically non significant. My present study revealed that prolonged duration of OCP use ( at least for 5 years) increases the risk of hypercoagulable state and thromboembolism in women.


2020 ◽  
Vol 9 ◽  
Author(s):  
Oscar F. Herran ◽  
Jhael N. Bermúdez ◽  
María Del Pilar Zea

Abstract The present study aimed to (a) establish the frequency of consumption of red meat and eggs; (b) determine serum ferritin levels (μg/l); and (c) establish the relationship between serum ferritin and the consumption of red meat and eggs. In Colombia during 2014–2018, an analytical study was conducted in 13 243 Colombian children between the ages of 5 and 17 years, based on cross-sectional data compiled by ENSIN-2015 (Encuesta Nacional de la Situación Nutricional en Colombia-2015) on serum ferritin levels and dietary consumption based on a questionnaire of the frequency of consumption. Using simple and multiple linear regression, with the serum ferritin level as the dependent variable and the frequency of consumption as the main explanatory variable, the crude and adjusted partial regression coefficients (β) between serum ferritin levels and consumption were calculated. The frequency of habitual consumption of red meat was 0⋅49 (95 % CI 0⋅47, 0⋅51) times/d. The frequency of habitual egg consumption was 0⋅76 (95 % CI 0⋅74, 0⋅78) times per d. The mean serum ferritin level in men was 41⋅9 (95 % CI 40⋅6, 43⋅1) μg/l and in women, 35⋅7 (95 % CI 34⋅3, 37⋅7) μg/l (P < 0⋅0001). The adjusted β between the consumption of red meat and eggs and serum ferritin levels were β = 3⋅0 (95 % CI 1⋅2, 4⋅7) and β = 2⋅5 (95 % CI 1⋅0, 3⋅9) for red meat and eggs, respectively. In conclusion, red meat and eggs are determinants of serum ferritin levels in Colombia and, therefore, could be considered public policy options to reduce anaemia and Fe deficiency.


2015 ◽  
Vol 2015 ◽  
pp. 1-5 ◽  
Author(s):  
Musa A. Sani ◽  
James O. Adewuyi ◽  
Abiola S. Babatunde ◽  
Hannah O. Olawumi ◽  
Rasaki O. Shittu

Objectives. Sickle cell anaemia (SCA) is one of the commonest genetic disorders in the world. It is characterized by anaemia, periodic attacks of thrombotic pain, and chronic systemic organ damage. Recent studies have suggested that individuals with SCA especially from developing countries are more likely to be iron deficient rather than have iron overload. The study aims to determine the iron status of SCA patients in Ilorin, Nigeria.Methods. A cross-sectional study of 45 SCA patients in steady state and 45 non-SCA controls was undertaken. FBC, blood film, sFC, sTfR, and sTfR/log sFC index were done on all subjects.Results. The mean patients’ serum ferritin (589.33 ± 427.61 ng/mL) was significantly higher than the mean serum ferritin of the controls (184.53 ± 119.74 ng/mL). The mean serum transferrin receptor of the patients (4.24 ± 0.17 μg/mL) was higher than that of the controls (3.96 ± 0.17 μg/mL) (p=0.290). The mean serum transferrin receptor (sTfR)/log serum ferritin index of the patients (1.65 ± 0.27 μg/mL) was significantly lower than that of the control (1.82 ± 0.18 μg/mL) (p=0.031).Conclusion. Iron deficiency is uncommon in SCA patients and periodic monitoring of the haematological, biochemical, and clinical features for iron status in SCA patients is advised.


2020 ◽  
Vol 27 (11) ◽  
pp. 2376-2382
Author(s):  
Hamzullah Khan ◽  
Mohammad Basharat

Objectives: To determine the correlation of Vit D3 levels with serum ferritin in patients with anemia. Study Design: Cross Sectional study. Setting: Department of Pathology, Qazi Hussain Ahmed Medical Complex Nowshera. Period: 5th Jan 2019 to 31st Dec 2020. Material & Methods: Data entered in SPSS 25th version. Descriptive statistics was used for numerical variables. Pearson correlation was used for correlation of Vit D3 with gender. Normality of data was checked by Shapiro wilk test. Mann Whitney U test was used to show the difference of Vit D3 and ferritin levels in gender. Results: The total of 192 anemic patients with Hb<10g/dl as per definition of WHO1 were referred for ferritin level estimation with 142(74%) females and 50(26%) males. Out of total, 47 were also advised with Vit D3 level estimation with 29(61.7%) females and 18(38.3%) males. Mean with standard deviation for age was 30+9.6 years. Mean with standard Error of mean of Vit D3 was (Mean-15.5ng/ml, SE 2.19). Mean with standard Error of mean of serum ferritin was (Mean-48.2ng/ml, SE 5.90). We observed 35(74.5%) cases out of 47, as Vit D3 deficient with a count less than 20 ng/ml. We observed that 118 (61.5%) were iron deficient with serum ferritin less than 15ng/ml. Person correlation showed a statistically significant correlation of Vit D3 with ferritin (p= 0.022, r=0.7). Spearman ranked correlation showed a statistically significant correlation between the categories of Vit D3 and ferritin (p=0.022, r=0.7). Mann Whitney U Test showed no significant difference in gender groups for botht the variables (p= 0.86 &p=0.33 respectively) thus retain the null hypotheses. Conclusion: The frequency of deficiency Vit D3<20ng/ml in anemic patients was 74% while that of ferritin<15ng/ml in anemic patients was 61.5%. There is a strong statistically significant correlation of Vit D3 with serum ferritin in anemic patients with Hb<11g/dl.


2016 ◽  
Vol 44 (1) ◽  
pp. 8-10
Author(s):  
Hosna Ara Perven ◽  
Abu Sadat Mohammad Nurunnabi ◽  
Dilruba Siddiqua ◽  
Fatema Johora ◽  
Halima Afroz ◽  
...  

This cross sectional, descriptive study was done in the Department of Anatomy, Dhaka Medical College, Dhaka from January to December 2009, to determine the proportion of cortex and medulla of the ovary in di_erent age group of Bangladeshi women. This study was based on collection of 140 ovaries of 70 unclaimed female dead bodies from the morgue of Dhaka Medical College, Dhaka. The samples were divided into three age-groups including A (10-13 years), B (14-45 years) & C (46-52 years). Histological slides were prepared by using routine haematoxylin and eosin stain. Ten best prepared histological slides from each age group were examined to determine the thickness of the cortex and medulla & proportion of the thickness of the cortex and the medulla of the ovary were expressed in percentages. The mean proportion of the cortex and the medulla of the right ovary were found 80.83±0.58% and 19.17±0.58% in group A, 86.95±1.14% and 13.05±1.14% in group B, 70.53±1.53% and 29.47±1.53% in group C respectively. The mean proportion of the cortex and the medulla of the left ovary were found 80.63±0.58% and 19.37±0.58% in group A, 86.78±1.14% and 13.22±1.14% in group B, 70.41±1.50% and 29.59±1.50% in group C respectively. The difference in mean proportion of the cortex and the medulla was not signi_cant in between the ovaries. However, the difference in mean proportion of the cortex and the medulla of the ovary between group A & group B, group A & group C and group B & group C were statistically significant.Bangladesh Med J. 2015 Jan; 44 (1): 8-10


2014 ◽  
Vol 11 (1) ◽  
pp. 11-14
Author(s):  
AHM Mostafa Kamal ◽  
Shamim Ara ◽  
Md Mesbahul Hoque ◽  
Khadeza Khatun ◽  
Kazi Afzalur Rahman

Context : The bones of the body are the last to pass away after death, next to enamel of teeth. Hence, in establishing the personal identity with respect to sex, age and stature, medico legal experts, anatomists and anthropologists use the skeletal materials for giving their opinion. Sex-dependent differences have been noted in the pelvic bone anatomy, and so differences exist in male and female sacrum. The aim of this study was to collect data regarding morphometric measurements of maximum length and breadth of sacrum and to find out possible variations of sacral index in different individuals in relation to sex. Material and Methods: A Cross-sectional, analytical type of study was conducted in the department of Anatomy, Dhaka Medical College, on 172 (one hundred seventy two) adult human dry sacra of unknown sex. The study samples were distributed in male and female sex groups by discriminant function analysis. All the samples were studied morphologically. Sacral length and breadth were measured with the help of digital slide calipers. Result : The mean sacral index in male and female were 97.88±6.16 % and 112.69±10.17 % respectively. Female has the greater sacral index than male (P<0.001) Conclusion: Sexing of sacrum, by sacral index method is relevant and significant DOI: http://dx.doi.org/10.3329/bja.v11i1.20502 Bangladesh Journal of Anatomy, January 2013, Vol. 11 No. 1 pp 11-14


2013 ◽  
Vol 22 (1) ◽  
pp. 34-38
Author(s):  
Sabiha Mahbub ◽  
Abu Sadat Mohammad Nurunnabi ◽  
Abdul Alim ◽  
Rukshana Ahmed ◽  
Shamim Ara

Context: A cross-sectional descriptive type of study was designed to find out the difference in weight of the parathyroid glands of Bangladeshi people in relation to age and sex and to compare with the previous studies. Methods: This study was done in the Department of Anatomy, Dhaka Medical College, Dhaka, from January to December 2008. The study was performed on 207 post mortem human parathyroid glands collected from 60 unclaimed dead bodies which were in the morgue under examination in the Department of Forensic Medicine, Dhaka Medical College, Dhaka. The samples were divided into three age-groups including group A (10-30 years), group B (31-60 years) & group C (61-90 years) and the weight of the parathyroids were measured and recorded. Results: The mean weight of the right superior parathyroid glands were 13.43±13.77 mg in group A, 13.86±19.15 mg in group B and 9.25±5.12 mg in group C in males and 16.00±6.69 mg in group A and 8.57±5.97 mg in group B in females respectively. The mean weight of the right inferior parathyroids were 17.78±13.94 mg, 16.75±15.67 mg and 23.00±11.53 mg in group A, B and C respectively in males and 26.00±4.18 mg in group A and 15.20±4.32 mg in group B in females. The mean weight of the left superior parathyroid glands were 13.63±6.08 mg in group A, 10.58±7.57 mg in group B and 11.00±3.74 mg in group C in males and 16.20±7.89 mg in group A and 8.29±5.47 mg in group B in females respectively. The mean weight of the left inferior parathyroid gland was 26.11±24.29 mg, 15.81±10.28 mg and 25.25±25.28 mg in group A, B and C respectively in males and 32.25±13.82 mg in group A and 13.29±5.41 mg in group B in females. No difference was found in the weight of superior parathyroid glands at right side between sexes and age groups excepting in superior and inferior parathyroid glands at left side between group A & B (p<0.05). DOI: http://dx.doi.org/10.3329/jdmc.v22i1.15603 J Dhaka Medical College, Vol. 22, No. 1, April, 2013, Page 34-38


2021 ◽  
Vol 16 (2) ◽  
pp. 190-195
Author(s):  
Carrina Nenggar Dewanti ◽  
I Ketut Alit Utamayasa ◽  
IDG Ugrasena

Background: Paediatric patients with transfusion dependent thalassemia require regular lifelong red cell transfusions. Blood transfusions increase the risk of iron overload, which can lead to cardiac hemosiderosis. Serum ferritin can be a parameter for evaluating systemic hemosiderosis. Objective: To evaluate the correlation between serum ferritin levels and impaired heart function in children with transfusion dependent thalassemia Methods: A cross sectional study was conducted with transfusion-dependent thalassemia who attended a cardiology and hemato-oncology outpatient clinic from January to December 2018 and had undergone more than 10 transfusion periods. Serum ferritin levels were taken from the mean of 3 measurements before echocardiography. Echocardiography examination was performed by a cardiologist using a 3D Doppler tool to evaluate ejection fraction (EF), tricuspid annular plane systolic excursion (TAPSE) and E / A ratio by calculating the initial diastole (E wave) and atrial contraction (wave A). Data analysis used the Spearman correlation with p <0.05. Results: There were 45 children with a median age of 10 (2-17) years and had received a median of 18 (10-51) blood transfusions. The mean serum ferritin level was 4,321 (1,168-15,233) ng / mL. Blood transfusion frequency was associated with an increase in serum ferritin (rho 0.74, P <0.005). From echocardiography examination, approximately 3/45 children had a feature of dilated cardiomyopathy. The mean value of EF 70 (SD 14.32), TAPSE 1.97 (SD 0.57) cm and an E / A ratio 1.68 (SD 0.46). Serum ferritin was negatively correlated with the ejection fraction (rho = -0.78, P <0.001), TAPSE (rho = -0.65, P <0.001) but positively correlated with the E / A ratio (rho = 0.67, P <0.001). Conclusion: Paediatric patients with TDT have decreased cardiac systolic and diastolic function, and serum ferritin correlates with the decreased cardiac function.


Author(s):  
Bhagyanath . ◽  
Jacob K. Jacob ◽  
Suma Samuel ◽  
Rakhi R. Kurup ◽  
Reshnu Ravindran

Background: Leptospirosis is a zoonotic infection with high mortality rates. The incidence of leptospirosis is more during floods. The aim of the study was to find the difference in clinical profile of leptospirosis during post flood and non-post flood periods.Methods: This was a cross sectional observational study comparing the clinical profile of leptospirosis patients admitted in Government Medical College Ernakulam, Kerala during the post flood period of 2018 with that of non-post flood period. The data with respect to clinical features and investigations were retrieved from the hospital records.Results: Out of the 42 patients studied 15 were from the post flood period and the rest 27 patients were from the non-post flood period. The mean age in the post flood group was 40 years and that in the non-post flood group 43 years. Myalgia, icterus and calf tenderness was significantly higher in the post flood group. The mean platelet count was significantly lower in the non-post flood period (p value=0.011). Mean serum urea and total bilirubin were significantly higher in the post flood group compared to non-post flood group (p value=0.001). Cardiac complications were seen only among the post flood group.Conclusions: The clinical profile and complications were different in leptospirosis patients during post flood and non-post flood periods. These findings help the treating physicians to formulate different approaches in treating patients during the post flood and non-post flood period.  


Sign in / Sign up

Export Citation Format

Share Document