scholarly journals Raised Vaginal Fluid Fibronectin Level Indicates Premature Rupture of Membrane

2012 ◽  
Vol 2 (2) ◽  
pp. 74-79
Author(s):  
Shamima Rahman ◽  
Samsad Jahan ◽  
Samira Humaira Habib ◽  
Nasrin Sultana ◽  
Mst Nigar Sultana ◽  
...  
Keyword(s):  
Normal Pregnancy ◽  
Clinical Situation ◽  
Cross Sectional Study ◽  
Clinical Event ◽  
Vaginal Fluid ◽  
Premature Rupture ◽  
Cross Sectional ◽  
Medical College ◽  
Group I ◽  
The Common

Background: Premature rupture of membrane (PROM) is one of the common complications  of pregnancy that has major impact on fetal and neonatal outcome. It is the commonest  clinical event where a normal pregnancy becomes suddenly a high-risk one for mother and  fetus or neonate. Objective: The study was undertaken to investigate whether raised  fibronectin level in vaginal fluid may indicate premature rupture of membrane. Materials and  Methods: This cross sectional study was conducted in the department of Obstetrics and  Gynecology in Sir Salimullah Medical College & Mitford Hospital, Dhaka during the period  of January 2006 to December 2007. A total of 114 pregnant women with gestational age 28th  week up to 40th week were included. Sixty were PROM (Group I) and 54 were non-PROM  (Group II) subjects. Fibronectin in vaginal fluid was measured by an immunochemical  reaction by nephelometer. Statistical analysis was done by SPSS version 10.0. Results: The  PROM patients had significantly higher concentration of fibronectin (225.77 ± 115.18 ng/mL)  compared to that in non-PROM subjects (8.04 ± 16.17 ng/mL) (p < 0.001). Conclusion: It  can be concluded that in cases of unequivocal rupture or intactness of the membranes, the  result of the fibronectin test corresponds well with the clinical situation. So fibronectin is a  sensitive test for detection of amniotic fluid in the vagina. DOI: http://dx.doi.org/10.3329/jemc.v2i2.12841 J Enam Med Col 2012; 2(2): 74-79

scholarly journals Alpha Feto Protein in vaginal fluid as a diagnostic marker of Premature rupture of membrane

2018 ◽  
Vol 10 (1) ◽  
pp. 335-338
Author(s):  
Nasreen Sultana ◽  
Shamima Rahman ◽  
Fakhruddin Ahmed ◽  
SK Ashraf Ullah
Keyword(s):  
Gold Standard ◽  
Normal Pregnancy ◽  
Vaginal Fluid ◽  
Sensitive Test ◽  
Premature Rupture ◽  
Paper Test ◽  
Cross Sectional ◽  
Group I ◽  
Alpha Feto Protein ◽  
Group Ii

Background : Premature Rupture of Membrane (PROM) is a significant obstetric emergency where a normal pregnancy suddenly becomes a high risk one. It can cause serious complications of mother and fetus. Patient’s history, per speculum vaginal with Nitrazine paper test and Fern test considered as gold standard for diagnosis of PROM. But these multiple tests are hazardous and time consuming. Therefore Alpha-Feto Protein (AFP) test is a single sensitive test for proper diagnosis of PROM. Objective : To evaluate the accuracy of Alpha-Feto protein in vaginal fluid as a diagnostic tool of PROM. Method : It was a cross sectional study, carried out among 120 pregnant women who had the gestational age between 28th to 40th week of pregnancy. Sample was collected purposively and divided into two groups. In group-I-62 suspected PROM patients were selected who gave the history of per vaginal watery discharge and was found positive in per speculum examination (P/S). In group-II-58 non PROM pregnant patients were selected. Then in group-I, Nitrazine paper test and Fern test were done to confirme PROM patients. Both groups AFP test was done by AxSYM auto analyzer. Finally the accuracy of AFP was evaluated against the gold standard test. Result : It was found that AFP concentration was significantly higher in group-I of suspected PROM patients (30- 502ng/ml) than in group-II (0-40ng/ml). Among 62 suspected PROM patients 49 were found gold standard (Nitrogen paper test and Fern test) positive. Out of these 49 confirmed PROM patients 48 was found positive in Alpha-Feto protein test. The sensitivity of AFP test was found 98%, specificity was 84.6% and accuracy was 95.1%. Conclusion : As Alpha-Feto protein in vaginal fluid was found highly accurate (95.1%) for diagnosis of PROM. Therefore, AFP test can be used as a single sensitive test for diagnosis of PROM. Northern International Medical College Journal Vol.10(1) Jul 2018: 335-338

Side Effects of Chemotherapy and Cancer Treatment in Tertiary Care Teaching Hospital

2016 ◽  
Vol 2 (1) ◽  
pp. 62-78
Author(s):  
. Hemraj ◽  
Raj Kumar ◽  
Sourabh Kosey ◽  
Amit Sharma ◽  
Nalini Negi
Keyword(s):  
Side Effects ◽  
Tertiary Care ◽  
Cross Sectional Study ◽  
Informational Needs ◽  
Cross Sectional ◽  
Clinical Pharmacists ◽  
Medical College ◽  
Related Information ◽  
The Common ◽  
Chemotherapy Patients

To determine the most common physical side effects experienced by local chemotherapy patients. Their perceptions of these side effects and informational needs from clinical pharmacists were also evaluated. This was a single center, observational cross-sectional study conducted at department of General Surgery, Guru Gobind Singh Medical College and Hospital, Faridkot, Punjab. A face to face interview was conducted. Information collected included chemotherapy related side effects after last chemotherapy experience, the most worrisome side effects, overlooked by healthcare professionals and the preferred method, amount and source of receiving related information. In this study, hundred patients were enrolled out of them 48 were male and 52 were female. When differential calculations was done, common side effects or adverse effects of chemotherapy in the patients of breast, lung cancer, Ovarian Cancer, Colon cancer, Prostate cancer, Lymphoma Cancer, Cervix cancer where there is much irregular medicine intake 57.4% may be due to common problem of joint pain reported by all the patients under study, with the consecutive problem of nausea and vomiting. The high prevalence of chemotherapy related side effects among local patients is a major concern and findings of their perceptions and informational needs may serve as a valuable guide for clinical pharmacists and physicians to help in side effect management. This study shows the common problems reported by the patients when they are suffering from cancer condition, according to their incidence perceptions as experienced by the patient, this will allow the physician and clinical pharmacist to effectively counsel and manage the common symptoms as reported prior to its occurrence in the patient, so that withdrawal can be checked.

Comparison of Heffner Criteria and Light Criteria in Differentiating Exudative and Transudative Pleural Effusion

2020 ◽  
Vol 22 (3) ◽  
pp. 141-145
Author(s):  
Krishna Chandra Devkota ◽  
S Hamal ◽  
PP Panta
Keyword(s):  
Pleural Effusion ◽  
Cross Sectional Study ◽  
Pleural Space ◽  
Sectional Study ◽  
Inclusion Criteria ◽  
Cross Sectional ◽  
Medical College ◽  
The Common ◽  
The Mean ◽  
Exudative Pleural Effusion

Pleural effusion is present when there is >15ml of fluid is accumulated in the pleural space. It can be divided into two types; exudative and transudative pleural effusion. Tuberculosis and parapneumonic effusion are the common cause of exudative pleural effusion whereas heart failure accounts for most of the cases of transudative pleural effusion. This study was a hospital based cross sectional study performed at Nepal Medical College during the period of January 2016-December 2016. A total of 50 patients who fulfilled the inclusion criteria were enrolled. Pleural effusion was confirmed by clinical examination and radiology. After confirmation of pleural effusion, pleural fluid was aspirated and was analysed for protein, LDH, cholesterol. The Heffner criteria was compared with Light criteria to classify exudative or transudative pleural effusion. Among 50 patients, 30 were male and 20 were female. The mean age of patient was 45.4±21.85 years. The sensitivity and specificity of using Light criteria to detect the two type of pleural effusion was 100% and 90.9%, whereas using Heffner criteria was 94.87%, 100% respectively(P<0.01). There are variety of causes for development of pleural effusion and no one criteria is definite to differentiate between exudative or transudative effusion. In this study Light criteria was more sensitive whereas Heffner criteria was more specific to classify exudative pleural effusion. Hence a combination of criteria might be useful in case where there is difficulty to identify the cause of pleural effusion.

scholarly journals TO STUDY THE ONSET AND PROGRESSION OF AIRWAY ABNORMALITY IN TERMS OF ALTERATION IN PFT IN ASYMPTOMATIC SMOKERS.

2019 ◽  
Vol 3 (11) ◽  
Author(s):  
Dr. Hitesh Kumar Solanki ◽  
Dr. Omnath P Yadav ◽  
Dr. Anita J Gojiya
Keyword(s):  
Lung Function ◽  
Cross Sectional Study ◽  
Cross Sectional ◽  
Medical College ◽  
Group I ◽  
Significant Difference ◽  
History Of ◽  
Young Smokers ◽  
The Mean ◽  
Group Ii

The study was conducted in department of physiology, B J Medical College, Ahmedabad from Mar. 2012 to Feb. 2013. This was a cross-sectional study to evaluate the effect of smoking on lung   function and serum lipids in asymptomatic smokers   and comparable non   smokers. The mean of the various spirometric parameters were calculated of the subjects for both the groups. The mean FVC in group I and group II was 2.60 ± 0.62 L and 4.10 ± 0.64L respectively. The mean FEV1 in group I was 1.91 ± 0.57L and     3.19 ± 0.77L in group II Group I had mean FEF25% - 75% and PEFR of 1.98 ± 0.67L/sec and 4.50 ± 1.57L/sec respectively. Group II had mean FEF25 – 75% of 4.22 ± 1.23L/sec and a mean PEFR of 7.22 ± 1.42L/sec. In young smokers and asymptomatic, still the spirometric values were significantly deranged as compared to controls. Even smokers with history of less pack years of smoking also had significant abnormalities of lung function. All he spirometric values in the two groups had statistically highly significant difference and were higher in non-smokers as compared to smokers. The spirometric values were reduced in smokers with history of smoking for as low as two pack years. Keywords: Progression, PFT, Asymptomatic & Smokers

scholarly journals A clinicopathological study of Rhinosporidiosis

2016 ◽  
Vol 21 (2) ◽  
pp. 94-96 ◽  
Author(s):  
Sharfuddin Mahmud ◽  
Rojibul Haque ◽  
Abdullah Al Mamun ◽  
Rafiul Alam ◽  
DGM Akaiduzzaman ◽  
...  
Keyword(s):  
Age Distribution ◽  
Cross Sectional Study ◽  
Anatomical Site ◽  
Upper Respiratory Tract ◽  
Cross Sectional ◽  
Male Predominance ◽  
Medical College ◽  
Site Distribution ◽  
The Common

Introduction: Rhinosporidiosis is one of the common tropical diseases in ENT practice in this subcontinent having the affinity for the mucosa of upper respiratory tract –chiefly the nose & nasopharynx. Though this chronic granulomatous disease is quite common in this subcontinent but its distribution is not even.Objectives: The aim of this study is to find out the age distribution, clinical sign-symptoms& attachment of rhinosporidiosis, that’s mean to establish the clinical profile of the patient.Method: A cross sectional study was done at the department of ENT & HNS, Sir Salimullah Medical College Mitford Hospital from January to December 2012. The study included 49 patients treated in this department and histologically proved.Rersults: Among 49 patients there was male predominance(37), female were-12. Majority of the patient presented with the feature of nasal obstruction(27), nasal mass(23) and it’s majority site of attachment was nasal septum(30). In anatomical site distribution majority cases(39) it was distributed in nose & nasopharynx.Conclusion: This study suggests total excision, wide base cauterization and regular follow up to prevent recurrence.Bangladesh J Otorhinolaryngol; October 2015; 21(2): 94-96

scholarly journals A comparative study of elective and emergency tracheostomy

1970 ◽  
Vol 14 (2) ◽  
pp. 57-62
Author(s):  
A Allam Choudhury ◽  
Tuhin Sultana ◽  
Md Abul Hasnat Joarder ◽  
Kamrul Hassan Tarafder
Keyword(s):  
Head Injury ◽  
Neck Surgery ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
College Hospital ◽  
Cross Sectional ◽  
Medical College ◽  
Emergency Tracheostomy ◽  
The Common ◽  
Elective Tracheostomy

This is a cross sectional study done in I.C.U & Dept. of otolaryngology - Head & Neck Surgery, B.S.M.M.U, Dhaka and Dhaka Medical College Hospital during the period of 1st March, 2003 to 30th August, 2003. 60 cases of tracheostomies, were included in this study, among them 30 cases of elective tracheostomies and 30 cases of emergency tracheostomies. In this study mean age of elective tracheostomy was 40.46 years & mean age of emergency tracheostomy was 50.50 years. Here Male was predominant both in elective (M:F= 6.5:1) and emergency tracheostomy (9:1). The common indications of elective tracheostomy were ICSOL (26.67%) & Head injury (26.67%) where as commonest indication of emergency tracheostomy was laryngeal carcinoma (53.33%). The frequency of complication for elective tracheostomy was 9.99% and emergency tracheostomy 33.35%. Here complications were 3.33 times more common in cases of emergency tracheostomy then elective tracheostomy. Key-words: Tracheostomy, elective and emergency.  DOI: 10.3329/bjo.v14i2.3282 Bangladesh J of Otorhinolaryngology 2008; 14(2) : 57-62

STUDY OF SERUM GHRELIN IN THYROID PATIENTS

2021 ◽  
pp. 140-142
Author(s):  
G.G. Kaushik ◽  
Kavita Sharma
Keyword(s):  
Thyroid Hormone ◽  
Healthy Subjects ◽  
Positive Association ◽  
Cross Sectional Study ◽  
Ghrelin Level ◽  
Cross Sectional ◽  
Group Iii ◽  
Medical College ◽  
Group I ◽  
Serum Ghrelin

Background: Hypothyroidism is a common endocrine disorder resulting from deciency of thyroid hormone. Hyperthyroidism is a set of disorders that involve excess synthesis and secretion of thyroid hormone by the thyroid gland. Ghrelin is octanoylated peptide containing a 28 amino acid act as an energy balance regulator & play an important role in metabolic process .The aim of the study was to establish possible relationship between them. Materials and methods: The present study is a cross sectional study, was conducted in the Department of Biochemistry, J.L.N. Medical college and associated group of Hospitals, Ajmer (Raj.). 65 hypothyroid subjects (group-II) and 65 hyperthyroid subjects (group-III) attending Medical OPD of J.L.N. Hospitals were included and 130 age-sex matched euthyroid controls (group-I) were selected. Results: In hypothyroid subjects, mean serum Ghrelin levels were found to be signicantly higher in comparison to healthy subjects (p<0.0001). In hyperthyroid subjects, mean serum Ghrelin levels were found to be signicantly lower in comparison to healthy subjects (p<0.0001). Conclusion: The overall ndings of the present study thus conrm that serum Ghrelin level is signicantly higher in Hypothyroid subjects and the level is signicantly lower in the Hyperthyroid subjects, thus we have found positive association between serum TSH level and Ghrelin level. However, further experimental and observational studies are needed to illustrate the role of Ghrelin in Hypothyroidism and Hyperthyroidism.

scholarly journals Study of Hartmann’s Pouch of the Gallbladder

2014 ◽  
Vol 2 (2) ◽  
pp. 68-70
Author(s):  
Laila Farzana Khan ◽  
Humaira Naushaba ◽  
Jahanara Begum ◽  
Md Shahjahan Chowdhury ◽  
Jubaida Gulshan Ara
Keyword(s):  
Gall Bladder ◽  
Cross Sectional Study ◽  
Common Site ◽  
Cross Sectional ◽  
Medical College ◽  
Normal Gallbladder ◽  
Right Lobe ◽  
The Common ◽  
The Right ◽  
Good Proportion

Background: The gall bladder is a hollow pear shaped sac lying within a fossa on the visceral surface of the right lobe of the liver. In the junction of neck of the gallbladder and the cystic duct, there is a pouch present called Hartman’s pouch or infundibulum of the gallbladder which is a frequent but inconstant feature of the normal gallbladder. It is the common site of lodged gallstones. Objective: To determine the proportion of presence of Hartman’s pouch in our population so that the concerned personnel might have a thought in mind that common pathologies of gall bladder may also involve this pouch. Materials and method: This cross sectional study was carried out in the department of Anatomy, Sir Salimullah Medical College & Mitford Hospital, Dhaka, Bangladesh, from July 2010 to June 2011. The number of sample was 62 postmortem human gallbladders which were collected from unclaimed dead bodies. Results: Hartmann’s pouch of the gallbladder was found in 45 (72.58%). Conclusion: Hartman’s pouch is present in a good proportion of our population. DOI: http://dx.doi.org/10.3329/dmcj.v2i2.20527 Delta Med Col J. Jul 2014; 2(2): 68-70

scholarly journals High Sensitive C-Reactive Protein (hs-CRP) and Its Correlation with Angiographic Severity of Patient with Coronary Artery Disease (CAD)

1970 ◽  
Vol 19 (2) ◽  
pp. 91-97 ◽  
Author(s):  
MA Hasnat ◽  
AEMM Islam ◽  
AW Chowdhury ◽  
HILR Khan ◽  
MZ Hossain
Keyword(s):  
Coronary Artery Disease ◽  
Coronary Artery ◽  
Cross Sectional Study ◽  
Cross Sectional ◽  
Medical College ◽  
Group I ◽  
Extent Score ◽  
Hs Crp ◽  
Artery Disease ◽  
Vessel Score

Background: Association between the plasma hs-CRP levels and the severity of coronary stenosis in subjects remains controversial. This cross sectional study was performed in the Department of Cardiology, Dhaka Medical College during July 2008 to December 2009, to determine whether the concentrations of hs-CRP correlate with the coronary atherosclerotic disease assessed by coronary angiography. Methods: For this purpose, a total number of 90 consecutive patients having IHD admitted in the Dhaka Medical College Hospitals were enrolled in this study. Patients were divided into three groups according to their level of hs-CRP. Out of 90 cases, 22(24.4%) patients were in group I, in group II 33(36.7%) patients and rest 35(38.9%) were in group III according to their hs-CRP level. Severity of CAD was assessed by vessel score, stenosis score and extent score. Result: Significant positive correlation (r=0.7409; p<0.001 r=0.6648; p<0.001 and r=0.6386; p<0.001) was found between hs-CRP and vessel score, stenosis score and hs-CRP and extent score suggesting increasing level of hs-CRP strongly suggestive of extensive coronary artery disease. Conclusion: High level of hs-CRP strongly suggestive of extensive coronary artery disease Key words: hs-CRP; angiogram; coronary artery disease; vessel score; stenosis score and extent score. DOI: 10.3329/jdmc.v19i2.7076J Dhaka Med Coll. 2010; 19(2) : 91-97

scholarly journals The Predictors of the Severity of Dengue Fever: A Cross-Sectional Study in a Tertiary Care Center of Bangladesh

2021 ◽  
Vol 29 (1) ◽  
pp. 77-82
Author(s):  
Mohammad Zaid Hossain ◽  
Nusrat Sultana ◽  
Afroza Akbar Sweety ◽  
Reaz Mahmud ◽  
Mohammed Masudul Hassan Khan ◽  
...  
Keyword(s):  
Platelet Count ◽  
Dengue Fever ◽  
Cross Sectional Study ◽  
Severe Dengue ◽  
P Value ◽  
Sectional Study ◽  
Cross Sectional ◽  
Medical College ◽  
Group I ◽  
Study Population

Background: Dengue is an endemic disease for Bangladesh with occasional outbreak. Little is known about the predictors of severe dengue. Methods: This cross sectional study was conducted in the medicine department of Dhaka Medical College from April 2019 to March 2020. Total 199 consecutive patients were enrolled in this study. For the purpose of the analysis, dengue fever was classified as group I and dengue hemorrhagic fever and dengue shock syndrome was classified as group II. Results: The mean (SD) age of the study population was 28.5(12.1) and 87.4% were less than 40 years of age. The male and female ratio was about 3:1. Among the total study population, 149(74.9%) patients had DF, 46 (23.1%) had DHF and only 4 (2%) had DSS on presentation. Baseline demography and clinical presentation did not significantly differ between classical dengue and severe dengue. Previous history of dengue had low association with severity (RR, 95%CI, phi, P value; 1.2, 1.04-1.40, 0.25, 0.001).Most of the laboratory parameters were similar between the groups. The number of platelet count was significantly lower in DHF and DSS [median (IQR) 43500(16500-95250], than DF [median (IQR) 65000(33000-1170000, p-value 0.01] Conclusion: Previous infection with dengue virus and decreasing platelet count are the predictors of the severe dengue. J Dhaka Medical College, Vol. 29, No.1, April, 2020, Page 77-82

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