scholarly journals Association of Hypertriglyceridemia with Ischemic Stroke, Study in a Tertiary Care Hospital in Bangladesh

2016 ◽  
Vol 17 (1) ◽  
pp. 21-26
Author(s):  
Md Enamul Karim ◽  
Shekhar Kumar Mondal ◽  
AKM Humayon Kabir ◽  
Partha Pratim Das ◽  
Sarmistha Biswas ◽  
...  

Background: Hypertriglyceridemia fosters the development of atherosclerosis via several mechanisms and lead to ischemic stroke (IS) through its contribution to thrombogenicity. The association of hypertriglyceridemia with ischemic stroke was evaluated in this study.Methods: This was a case control study conducted in the Department of Medicine, Dhaka Medical College Hospital and data was collected in a questionnaire from January to June’2013. Patients presented with ischemic stroke, confirmed by CT scan of Head/ MRI of brain from 1 day to 6 months and other than ischemic stroke patients were considered as case and control respectively.Results: The mean age was found 61.0±8.3 years in case group and 60.5±8.1 years in control group. Male were predominant in both groups which was 80 (80.0%) in case group and 84 (84.0%) in control group. More than two third (68.0%) in cases and one fourth (25.0%) in controls patients had hypertension. 12 (12.0%) in cases and 2 (2.0%) in controls patients had heart disease. Normal triglycerides was found 52 (52.0%) in cases and 72 (72.0%) in control. The mean TG was found 179.9±62.8 mg/dl in cases and 148.0±51.9 mg/dl in controls. Desirable cholesterol was found 16 (16.0%) in cases and 25 (25.0%) in controls. The mean cholesterol was found 238.0±4.0 mg/dl in cases and 213.0±42.0 in controls. Optimal LDL was found 12 (12.0%) and 18 (18.0%) in case and control group respectively. Mean LDL was found 167.0±35.2 mg/dl in cases and 141.0±36.1 mg/dl in controls. Low HDL was found 64 (64.0%) in cases and 26 (26.0%) in controls. Mean HDL was found 41.2±10.6 mg/dl in case group and 49.0±8.6 mg/dl in control group.Conclusion: Ischemic stroke is significantly associated with a higher level of TC, TG, LDL and HDL (inversely). Therefore, Hypercholesterolemia and Hypertriglyceridemia may be a risk factor for ischemic stroke.J MEDICINE January 2016; 17 (1) : 21-26

2013 ◽  
Vol 5 (2) ◽  
pp. 91-94
Author(s):  
Md Akram Hossain ◽  
Md. Eakub Ali ◽  
Ishrat Bhuiyan ◽  
Md. Shahadat Hossain ◽  
Biswas Shahin

Background: Psoriasis is multifactorial in origin. Streptococcal infection, sore throat has been claimed to be an  infectious  cause.Objective: The  purpose  of  the  present  study  was  to  observe  the  association  of Streptococcus with guttate psoriasis.Methodology: This was an observational case-control study which was conducted in the Department of Dermatology & Venereology at Bangabandhu Sheikh Mujib Medical University (BSMMU), & Shaheed Suhrawardy Medical College hospital (ShSMCH) in Dhaka city of Bangladesh during the period of February 2012  to October 2012. Patients clinically and histopathologically diagnosed as psoriasis were selected as case group and patients with skin diseases other than psoriasis were selected as control group.Results: A total of 115 patients were included in this study of which 64 patients were in case group and the rest 51 patients were designated as control group. The mean age was 30.73±14.69 years and 26.47±12.64 years in cases and control groups respectively (p>0.05). About 66.6% patients gave a positive history of sore throat. ASO titer was raised (>200 IU/ml) in 25(83.3%) patients of guttate psoriasis and 5(23.8%) in patients of their non-psoriatic controls (p<0.05). Streptococcus pyogenes was found in 9(30.0%) patients of case group and only 2(9.5%) patients were found in their control group.Conclusion: Streptococcal throat infections are associated with guttate psoriasis patients.DOI: http://dx.doi.org/10.3329/jssmc.v5i2.20763J Shaheed Suhrawardy Med Coll, 2013;5(2):91-94


2020 ◽  
Vol 6 (2) ◽  
pp. 114-117
Author(s):  
Shimul Akter ◽  
Naznin Rashid Shewly ◽  
Kashefa Khatun ◽  
Rokshana Parvin Nupur ◽  
Kamrun Nahar ◽  
...  

Background: Vesico-vaginal fistula can occur in different women with varied socio-economic condition. Objectives: The purpose of the present study was to see the socio-demographic characteristics of vesico-vaginal fistula (VVF) patients attended at a tertiary care hospital in Bangladesh. Methodology: This cross-sectional study was carried out from July 2013 to December 2013 for a period of 6 months in the National Fistula Centre in the Department of Obstetrics & Gynaecology at Dhaka Medical College Hospital (DMCH), Dhaka, Bangladesh. All patients who underwent surgical repair for iatrogenic VVF in National Fistula Centre of the department of Obstetrics and Gynaecology of Dhaka Medical College Hospital were included in this study. Patients who got themselves admitted to Obstetrics & Gynaecology department of DMCH with the complaints of fistula. The entire selected patients were interviewed for detailed socio-demographic characteristics. Result: A total number of 51 cases of VVF were recruited for this study. The mean age was 46.02 (±SD 6.104) years. Most of the respondents were illiterate (55.0%) and one-third patients had primary level education. The number of highly educated patients was scarce (12.0%). It was evident that average age at marriage of the patients was 15.8(±4.74) years. Some females were forced to accept marriage at the age of 10 years. The mean interval between initiation of menstruation and the marriage was only 4.72 years. Mothers were on an average 17.48 years old at the time of first delivery. Conclusion: In conclusion middle age illiterate women are most commonly suffering from VVF. Journal of National Institute of Neurosciences Bangladesh, 2020;6(2): 114-117


Author(s):  
B. Khanam ◽  
M. Imran Khan ◽  
Ajay Kumar Singh ◽  
Sumit Solanki ◽  
S.M. Holkar

Background: Few studies have assessed the relation of hyperuricacidemia with the acute coronary syndrome (ACS). This study investigated the association between high uric acid levels with the presence and severity of ACS.  Methods: Three hundred and seventy patients having angiographic evidence of atherosclerosis (CAD + case group) compared to 170 patients with no luminal stenosis (n=110) or with <50% luminal stenosis (n=60) at coronary angiography (CAD – control group). Results: The mean age of the patients was 60 ± 10 years (317 men, 58.7%). Hyperuricacidemia was more likely associated with a trend toward higher vessel scores, indicating a more severe CAD (adjusted OR=1.51, 95% CI=1.09-2.09; P=0.005) in the whole population. A comparison of sex-specific values showed a significant association existed only in men. Conclusions: Asymptomatic hyperuricacidemia may be associated with the presence and severity of ACS. Keywords: Hyperuricacidemia, Severity & Acute Coronary Syndrome.


Author(s):  
Neelam Jhajharia ◽  
Madhureema Verma

Background: Pregnancy induced hypertension (PIH) is one of the most common and potential life-threatening complications of pregnancy. This study is aimed to investigate and correlate the hemoglobin, haematocrit, white blood cell count, lymphocytes and platelets in PIH patients in their third trimester.Method: Total 126 subjects were studied out of them 63 patients (case) and 63 healthy pregnant women (control) visiting the Obstetrics and Gynaecology department Jhalawar Medical College, Jhalawar were registered in the study and followed during their pregnancy. Two millilitre of blood sample was drawn aseptically using the 5ml syringe from the median ante cubital vein of all the cases and control participants into EDTA-anticoagulated tubes. Haematological parameter calculated by using Sysmex XN-9100™ Automated Haematology System.Results: The mean hemoglobin level of the case group (8.8206±2.53779) was significantly lower than that of the control group (9.7289±2.47033) (p<0.05). The mean platelet count of the case group (131.4937±62.05999) was significantly lower than that of the control group (324.9683±230.78764) (p<0.05). The mean lymphocytes level of case group (1.2510±0.56369) was significantly lower than that of the control group (1.9295±1.4150) (p<0.05). The mean WBC level of case group (36.3467±119.90635) was significantly high than control group (11.5260±4.83059) (p<0.05). The mean haematocrit level of case group (32.6851±7.29789) was significantly high than control group (30.0424±23.38116) (p<0.05).Conclusion: The mean hemoglobin, mean platelets and mean lymphocytes are lower in PIH patients. The mean WBC and haematocrit are higher in PIH patient. 


2016 ◽  
Vol 45 (1) ◽  
pp. 20-24
Author(s):  
Md Ferdous Mian ◽  
Mohammad Jobayer ◽  
Zeenat Afroz ◽  
Ahmed Hossain Chowdhury ◽  
Rajib Nayan Chowdhury ◽  
...  

There are about 2 million epilepsy patients in Bangladesh. The aim of this study was to correlate the demographic parameter of epilepsy patients with their knowledge about the disease and also with the compliance of antiepileptic drugs. This retrospective study was carried out in the Department of Neurology at Dhaka Medical College Hospital, Bangladesh from July 2010 to June 2012. A total of 100 epilepsy patients of any age and sex attending the epilepsy clinic were enrolled of which 50 patients who had experienced one or more seizures over last six months were designated as uncontrolled epileptic patients were in case group and 50 patients who were seizure-free for six months were designated as controlled epileptic patients were in control group. Mean age of case and control groups were 21.84 ±8.70 and 23.94 ±10.28 years respectively. Most of the epilepsy patients were between the age of 11 to 30 years that was 88% in case group and 76% in control group. Male was predominant than female in both group. Among study population 70% and 58% had educational status below Primary level in case and control group respectively. Seventy percent of uncontrolled epilepsy patients were from low income group and 62% of them were unemployed. Maximum (68% in case and 44% in control group) patients were from rural area. Almost all controlled epilepsy patients took drugs regularly, whereas 52% patients with uncontrolled epilepsy did not took drugs regularly and 64% of them had history of missing anti-epileptic drugs. Knowledge about the disease, treatment and prognosis of epilepsy was better in control group than in case group of epilepsy patients. It may be concluded that lower socioeconomical condition, less education and lack of awareness about epilepsy and non-affordability, limited availability of drugs, lack of counseling have contributed to the non-compliance of antiepileptic drugs.Bangladesh Med J. 2016 Jan; 45 (1): 20-24


2018 ◽  
Vol 16 (1) ◽  
pp. 7-10
Author(s):  
Tanveer Ahmed Khan

Introduction: Headaches are the most prevalent neurological disorders and among the most frequent symptoms seen in general practice among which migraine only accounts up to 30%. Certain factors are found to play role in the triggering of migraine headache. Avoidance of such factors is part of migraine management. Psychiatric co morbidities are common in migraine. Recognizing these co morbidities could therefore result in improved patient management. Methods: This study was done at Nepalgunj medical college hospital, Nepalgunj. Duration of study was six months i.e. from 1st July 2017 to 31st December 2017. All the new cases fulfilling diagnostic criteria of migraine headache visiting to psychiatric outpatient department were included in this study. The diagnosis of migraine was made based on criteria mentioned by the international classification of headache disorders (ICHD-II). Result: A total of 50 patients were enrolled in this study. The mean age of participants was 28.60 ± 10.388 years. There was significant predominance of female participants. Family history of migraine was found in 20 (40%) of participants. The mean age of onset was 22.76± 7.899 years. The commonest type of migraine was migraine without aura in 2/3rd number of cases. Psychiatric co-morbidity was found in 26 (52%) subjects among which the most common co-morbidity was anxiety disorder in 16 (32%) followed by depression in 8 (16%). Presence of provoking factors was found in 38 (76%) subjects. Light, smoke, smell, noise and lack of adequate sleep were the common provoking factors. Conclusion: Migraine predominantly affects females with common age of onset in second and third decade. Psychiatric co-morbidities are common in migraine patients. Anxiety disorder and depression are the commonest co-morbidities. The common provoking factors are light, smoke, smell, noise and lack of adequate sleep found in migraine. Avoidance of provoking factors and early detection and management of psychiatric co morbidities can result in better outcome.


Author(s):  
Rubina Yasmin ◽  
Rahnuma Parveen ◽  
Nazim Al Azad ◽  
Sudip Ranjan Deb ◽  
Nandita Paul ◽  
...  

Background: Health care workers (HCWs) are at high risk of acquiring infections during this ongoing COVID-19 outbreak. This study was aimed at determining the prevalence of SARS-CoV-2 infection, the socio demographic and clinical profile and the possible risk factors for infection among the HCWs at Mugda Medical College Hospital (MuMCH). Method: This retrospective observational study was done among the HCWs of MuMCH from 19 April, 2020 to 15 May, 2020. The SARS-CoV-2 positive 37 HCWs were interviewed over telephone by a structured questionnaire and the obtained data were analyzed by using descriptive statistics. Result: Out of total 343 HCWs, total 37(10.79%) cases were detected COVID-19 positive. Out of them, 13(35.14%) were male and 24 (64.86%) were female. The median age was 36 years. Among the infected HCWs, 26 (70.27%) did not have any pre-existing comorbidities. Bronchial asthma (13.51%) and HTN (13.51%) were the most prevalent comorbidities. Around 43.24% (16) had no definite symptoms for COVID- 19. Among the 21(56.76%) symptomatic cases, 15(40.54%) had mild and 6(16.22%) had moderate symptoms. The most common symptoms were cough (16, 43.24%), fever (11, 29.73%), sore throat (7, 18.92%) and fatigue/malaise (7, 18.92%). All had completely recovered uneventfully although 22(59.46%) got admitted to hospital. Only 12(32.43%) were involved in aerosol generating procedure. Total 26 cases (70.27%) used appropriate PPE during their duty. Although only 4(10.81%) got adequate training on PPE use, 33(89.19%) of them had adequate knowledge on that. About 15(40.54%) were reusing PPEs. Most of them (33, 89.20%) were not taking any chemoprophylaxis; all were following traditional preventive measures. Among the HCWs, 26(70.27%) were not satisfied with the infection prevention and control (IPC) measures taken by the hospital authority. All of them presumed that, their occupational exposure was the possible source of COVID-19 infection. Conclusion: More than 1 in 10 HCWs at MuMCH was infected with SARS-CoV-2 while working at the hospital. They represented the younger age group, had fewer comorbidities. Nurses were the most affected category. All experienced uneventful recovery and most of them were not satisfied with the IPC measures taken by the hospital authority. Further studies are required to identify the level of risk of infection, possible risk factors and outcomes and to improve the IPC measures of the hospital. J Bangladesh Coll Phys Surg 2020; 38(0): 43-49


2016 ◽  
Vol 5 (2) ◽  
pp. 29-32
Author(s):  
Masuda Khatun ◽  
Mollah Md Abu Sayed ◽  
MD Shah Alam ◽  
Farida Yeasmin ◽  
Lubna Khondker

Various forms of skin disease like psoriasis have been found to show disturbances in systemic calcium metabolism in some cases. Calcium is the major regulator of keratinocytes differentiation. The main objective of this study was to find out the serum calcium level of patients with psoriasis in comparison with control subjects without psoriasis. The present study was a case control study from July 2015 to June 2016. Consecutive type of sampling method was followed in this study. The case group was consisting of 30 psoriatic patients and the control group was consisting of 30 non psoriatic patients attended in Skin and VD department of Dhaka Medical College Hospital (DMCH) and Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka. The mean age of the psoriatic group was 35.57±7.75 years (minimum 22 years and maximum 50 years), while it was 35.17±7.32 years (minimum 23 years and maximum 48 years) in the control group. The mean serum calcium level in psoriatic patients was 8.84±0.95 mg/dl (minimum 7.2mg/dl and maximum 10.2 mg/dl) while in controls it was 9.49±0.90 mg/dl (minimum 7.7 mg/dl and maximum 10.9 mg/dl). Statistical difference was observed between case and control participants with p-value <0.05. Hypocalcemia was observed in 33.33% psoriatic patients as compared 10% in controls (P value <0.05). In conclusion, serum calcium levels were lower in psoriatic patients than in control subjects. It is better to include dairy foods as calcium resource in daily diet of patients suffering from psoriasis. CBMJ 2016 July: Vol. 05 No. 02 P: 29-32


Esculapio ◽  
2020 ◽  
Vol 16 (03, july 2020-Septmber 2020) ◽  
Author(s):  
Shamila Ijaz Munir ◽  
Falak Naseer ◽  
Amna Ahsan ◽  
Mahnaz Gondal, ◽  
Nazia Khalil ◽  
...  

Objective: To determine the relationship between periodontitis and preterm labour in pregnant women presenting to a tertiary care hospital in Lahore. Methods: This case control study was conducted at Obstetrics & Gynecology Unit 4 of Sir Ganga Ram Hospital, Lahore for six months. The delivering women, who consented to participate, were divided into two case and control groups. For each case one control was enrolled who met the inclusion criteria, so total sample size was 380 women. Women delivered before 37 weeks of gestation were case group and those delivered after 37 weeks were control group. A patient was considered having periodontitis if she had probing pocket depth of ≥3mm in at least 3 sites. Data was collected and analyzed on SPSS version 21. Results: In this study the mean age of the case group patients was 28.52±6.45 years while of the control group was 28.67±6.35 years. The mean value of probing depth pocket in the case group was 3.872±1.37 while the mean value probing depth pocket of the control group was 3.58±1.52. Out of 380 patients the periodontitis was found in 275 patients. The odds of having periodontitis in case group was 1.85 times higher than control group i.e. OR=1.85[1.17-2.92]. Conclusion: Periodontitis is a preventable risk factor of preterm labour in women presenting at a tertiary care hospital. Keywords: Preterm Labour, Periodontitis, dental hygiene, preterm delivery


2018 ◽  
Vol 5 (4) ◽  
pp. 1447
Author(s):  
Sundar K. C. ◽  
Devi Meenakshi K. ◽  
Aruna B. Patil

Background: Retinopathy of prematurity (ROP) affects developing retinal vasculature in premature infants. The risk factors for ROP are prematurity, low birth weight, oxygenation, respiratory distress, infection and frequent blood transfusion. Identification of risk factors leading to ROP may help in planning preventive strategies.Methods: A retrospective analysis of records of preterm babies less than 34 weeks of gestation or birth weight less than 1750 grams and between 34 -36 weeks gestation or 1750-2000 grams birth weight associated with risk factors for ROP admitted to NICU of Kilpauk Medical college hospital from August 2015 to July 2016 were evaluated.Results: Out of a total of 166 babies who were screened for ROP, 37 babies were detected to have ROP (22.3 %). Of these 20 (54%) were female and 17 (46%) were male. The mean birth weight of babies with ROP identified in our study was 1480 grams. The mean gestational age of babies with ROP was 32 weeks. By logistic regression analysis for mode of oxygen therapy as a risk factor for ROP it was found that prongs alone showed the strong risk factor towards ROP which was statistically significant. Sepsis, transfusion and shock requiring inotropes individually and statistical significantly contributed to the risk of ROP.Conclusions: ROP was more common in babies <34 weeks. Sepsis, transfusion and shock requiring inotropes significantly contributed to the risk of ROP. Analysis of the mode of oxygen therapy showed that use of prongs significantly increased the risk of ROP.


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